Changes in Sperm Characteristics and Induction of Oxidative Stress in the Testis and Epididymis of Experimental Rats by a Herbicide, Atrazine

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Archives of Environmental Contamination and Toxicology

• Publication date

  2010-04-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s00244-009-9371-2PMID 19672647
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Methods of Enzymatic Analysis

  2019cited by this paper
• Tetracycline-induced reproductive toxicity in male rats: effects of vitamin C and N-acetylcysteine.

  2008cited by this paper
• Curcumin and kolaviron ameliorate di-n-butylphthalate-induced testicular damage in rats.

  2007cited by this paper
• Chemoprotective effect of melatonin against cisplatin‐induced testicular toxicity in rats

  2006cited by this paper
• Urinary pesticide concentrations among children, mothers and fathers living in farm and non-farm households in iowa.

  2006cited by this paper
• The effect of ascorbic acid supplementation on sperm quality, lipid peroxidation and testosterone levels of male Wistar rats.

  2005cited by this paper
• Lipoic acid ameliorates adriamycin-induced testicular mitochondriopathy.

  2005cited by this paper
• Atrazine and the hypothalamo-pituitary-gonadal axis in sexually maturing precocial birds: studies in male Japanese quail.

  2005cited by this paper
• Reference values of oxidative stress parameters (MDA, SOD, CAT) in dogs and cats

  2005cited by this paper
• Oxidative stress and endocrine endpoints in white sucker (Catostomus commersoni) from a river impacted by agricultural chemicals

  2005cited by this paper
• Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome.

  2004cited by this paper
• Diffuse atrazine pollution in German aquifers

  2004cited by this paper
• Remedial effect of DL-α-lipoic acid against adriamycin induced testicular lipid peroxidation

  2004cited by this paper
• There Is No Denying This: Defusing the Confusion about Atrazine

  2004cited by this paper
• Testicular and spermatotoxic effects of quinalphos in rats

  2003cited by this paper
• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress in the epididymis and epididymal sperm of adult rats

  2003cited by this paper
• Man and the workplace:: Assessing his reproductive health

  2003cited by this paper
• Semen quality in relation to biomarkers of pesticide exposure.

  2003cited by this paper
• Effect of methoxychlor on the antioxidant system in mitochondrial and microsome-rich fractions of rat testis.

  2002cited by this paper
• Effect of nonylphenol on the antioxidant system in epididymal sperm of rats

  2002cited by this paper
• The effects of atrazine metabolites on puberty and thyroid function in the male Wistar rat.

  2002cited by this paper
• Endocrine disrupting compounds and farm animals: their properties, actions and routes of exposure.

  2002cited by this paper
• Effects of molybdenum on fertility of male rats

  2002cited by this paper
• Atrazine inhibition of testosterone production in rat males following peripubertal exposure.

  2002cited by this paper
• Atrazine-induced hermaphroditism at 0.1 ppb in American leopard frogs (Rana pipiens): laboratory and field evidence.

  2002cited by this paper
• Response of the amphibian tadpole (Xenopus laevis) to atrazine during sexual differentiation of the testis

  2002cited by this paper
• Induction of oxidative stress in the rat testis after short-term exposure to the organochlorine pesticide methoxychlor

  2002cited by this paper
• Effect of lindane on antioxidant enzymes in epididymis and epididymal sperm of adult rats.

  2001cited by this paper
• Atrazine effects on testosterone levels and androgen-dependent reproductive organs in peripubertal male rats.

  2001cited by this paper
• Pathogenesis of Male Reproductive Toxicity

  2001cited by this paper
• Diphenyl diselenide and ascorbic acid changes deposition of selenium and ascorbic acid in liver and brain of mice.

  2001cited by this paper
• Urinalysis of atrazine exposure in farm pesticide applicators

  2000cited by this paper
• Atrazine disrupts the hypothalamic control of pituitary-ovarian function.

  2000cited by this paper
• Chemoprevention of 2-acetylaminofluorene-induced hepatotoxicity and lipid peroxidation in rats by kolaviron--a Garcinia kola seed extract.

  2000cited by this paper
• Effect of atrazine on implantation and early pregnancy in 4 strains of rats.

  2000cited by this paper
• Disorders of male rat reproductive tract under the influence of atrazine

  2000influential reference
• The effect of atrazine on puberty in male wistar rats: an evaluation in the protocol for the assessment of pubertal development and thyroid function.

  2000cited by this paper
• Nutritional influences on the hormonal control of reproduction in female pigs

  2000cited by this paper
• HPLC-accelerator MS measurement of atrazine metabolites in human urine after dermal exposure.

  1999cited by this paper
• Reactive oxygen species: oxidative damage and pathogenesis

  1999cited by this paper
• Neuroendocrine and reproductive effects of contemporary-use pesticides

  1999cited by this paper
• A risk characterization for atrazine: oncogenicity profile.

  1999cited by this paper
• Maternal exposure to atrazine during lactation suppresses suckling-induced prolactin release and results in prostatitis in the adult offspring.

  1999cited by this paper
• Effects of environmental toxicants on the efferent ducts, epididymis and fertility.

  1998cited by this paper
• Sperm motion predicts fertility in male hamsters treated with alpha-chlorohydrin.

  1997cited by this paper
• Effect of s‐triazine compounds on testosterone metabolism in the rat prostate

  1995cited by this paper
• In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides.

  1995cited by this paper
• [18] Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides

  1994cited by this paper
• Effects of atrazine on reproductive performance in the rat

  1994cited by this paper
• Identification and localization of copper-zinc superoxide dismutase gene expression in rat testicular development.

  1993cited by this paper
• Evidence for decreasing quality of semen during past 50 years.

  1992cited by this paper
• Pesticide contamination of ground water in the United States--a review.

  1990cited by this paper
• Testosterone metabolism in neuroendocrine organs in male rats under atrazine and deethylatrazine influence.

  1989cited by this paper
• Teratological evaluations of atrazine technical, a triazine herbicide, in rats and rabbits.

  1988cited by this paper
• [30] γ-Glutamyl transpeptidase

  1981cited by this paper
• Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction.

  1979cited by this paper
• Daily sperm production and epididymal sperm reserves of pubertal and adult rats.

  1978influential reference
• The Induction of Sperm-shape Abnormalities in Mice and Humans.

  1978cited by this paper
• Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

  1974cited by this paper
• The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase.

  1972cited by this paper
• Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent.

  1968cited by this paper
• FATE OF SPERMATOZOA IN CASES OF OBSTRUCTIVE AZOOSPERMIA AND AFTER LIGATION OF VAS DEFERENS IN MAN.

  1964cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• A Review on the Effects of Atrazine on Male Rat Reproductive System Cytoarchitecture, Steroidogenesis and Oxidative Pathway

  2026influential citation
• Evaluation of the immunotoxicity of atrazine and its chloro-metabolites: relevance for human cancer.

  2026cites this paper
• Environmental contamination and male reproductive health: (ir) reversible effects in child- and adulthood.

  2025cites this paper
• Atrazine’s effects on mammalian physiology

  2025cites this paper
• Impact of Sub-Chronic Exposure to Kalach on male reproductive system and sperm function: In Silico Modelling and In Vivo Study in Rats.

  2025cites this paper
• Protective effects of ascorbic acid on busulfan-induced oxidative damage and testicular function in Wistar rats

  2025cites this paper
• Impact of Embryonic Exposure of Atrazine on the Physiological and Behavioral Parameters in Drosophila melanogaster

  2025cites this paper
• Atrazine alters nitric oxide secretion and cytokines production in LPS-stimulated BalB/c mice, RAW264.7 macrophage and THP-1 cell lines.

  2025cites this paper
• Atrazine Induces Reproductive Toxicity in an In Vitro Spermatogenesis (IVS) Model

  2025cites this paper
• From toxicogenomics data to cumulative assessment groups: a framework for chemical grouping

  2025cites this paper
• Endocrine Disrupting Agents: Toxicological Aspects on Male Reproduction

  2025cites this paper
• Potential risk of premature ovarian insufficiency from atrazine exposure: insights into molecular pathways and regulatory implications

  2025cites this paper
• Endocrine toxicity of atrazine and its underlying mechanisms.

  2024cites this paper
• EMAMECTIN BENZOATE EXPOSURE IMPAIRED GERM CELL MATURATION IN THE TESTES OF ADULT ALBINO RATS

  2024cites this paper
• Influence of triazines and lipopolysaccharide coexposure on inflammatory response and histopathological changes in the testis and liver of BalB/c mice

  2024cites this paper
• Effects of atrazine and curcumin exposure on TCMK-1 cells: Oxidative damage, pyroptosis and cell cycle arrest.

  2024cites this paper
• Effect of quercetin administration on electron microscopic changes in testicular interstitial endocrinocytes during long-term central blockade of luteinising hormone in rats

  2024cites this paper
• Ascorbic acid attenuates gasoline-induced testicular toxicity, sperm quality deterioration, and testosterone imbalance in rats

  2024cites this paper
• Testicular weight deficits, altered variables of antioxidant defense system, spermatogenesis impairment, and inflammation induced by busulfan injection are ameliorated by gallic acid administration in rats

  2024cites this paper
• Bisphenol H exposure disrupts Leydig cell function in adult rats via oxidative stress-mediated m6A modifications: Implications for reproductive toxicity.

  2024cites this paper
• Acute effects of atrazine on the immunoexpressions of Sertoli and germ cells molecular markers, cytokines, chemokines, and sex hormones levels in mice testes and epididymides.

  2024cites this paper
• Assessing the Risks of Pesticide Exposure: Implications for Endocrine Disruption and Male Fertility

  2024cites this paper
• Exposure to toxicologically relevant atrazine concentrations impair the glycolytic function of mouse Sertoli cells through the downregulation of lactate dehydrogenase.

  2024cites this paper
• Testosterone Prevents atrazine-Induced Oxidative Damage, Inflammation and Histologic Changes in the Testes of Young Mature Rats

  2023influential citation
• The ROS/SIRT1/STAR axis as a target for melatonin ameliorating atrazine-induced mitochondrial dysfunction and steroid disorders in granulosa cells.

  2023cites this paper
• Atrazine exposure caused oxidative stress in male rats and inhibited brain‐pituitary‐testicular functions

  2023cites this paper
• AOP Report: Glutathione Conjugation Leading to Reproductive Dysfunction via Oxidative Stress

  2023cites this paper
• Testosterone restores TM3 and TM4 cell viability, reduces reactive oxygen species generation, and protects against atrazine‐induced stereological changes in rat testes

  2023cites this paper
• Atrazine: cytotoxicity, oxidative stress, apoptosis, testicular effects and chemopreventive Interventions

  2023cites this paper
• Testosterone modulates atrazine-induced cytotoxicity in testicular cell lines

  2023cites this paper
• Differentiation Disorders of Chara vulgaris Spermatids following Treatment with Propyzamide

  2023cites this paper
• Investigation of the Effect of Olanzapine and L-Carnitine on Rat Testis Tissue

  2023cites this paper
• Implications of atrazine concentrations in drinking water from Ijebu-North, Southwest Nigeria on the hypothalamic-pituitary-adrenal axis

  2023cites this paper
• Impact of Chronic Multi-Generational Exposure to an Environmentally Relevant Atrazine Concentration on Testicular Development and Function in Mice

  2023cites this paper
• Spermatogenic and antiradical activities of the hydro-ethanolic extract of Strychnos camptoneura (longaniaceae) trunk barks in Wistar rats

  2023cites this paper
• Role of N-acetyl cysteine in mitigates testicular abnormalities in male rats induced by Atrazine

  2022cites this paper
• An In Vitro Method to Study Male Reproductive Toxicology: A Review on the Bio-AlteR® Technology Allowing a “Physio-Toxicology” Approach

  2022cites this paper
• Palliative Effect of Resveratrol against Nanosized Iron Oxide-Induced Oxidative Stress and Steroidogenesis-Related Genes Dysregulation in Testicular Tissue of Adult Male Rats

  2022influential citation
• Histopathological, immunohistochemical, and molecular investigation of atrazine toxic effect on some organs of adult male albino rats with a screening of Acacia nilotica as a protective trial

  2022cites this paper
• Curcumin improves the protective effects of quercetin against atrazine‐induced testicular injury in adult Wistar rats

  2022influential citation
• Biochemical Effects of Treatments with Herbicide Atrazine in Male Albino Rats

  2022influential citation
• A Common Feature of Pesticides: Oxidative Stress—The Role of Oxidative Stress in Pesticide-Induced Toxicity

  2022cites this paper
• Environmental relevant herbicide prometryn induces developmental toxicity in the early life stages of marine medaka (Oryzias melastigma) and its potential mechanism.

  2022cites this paper
• Histopathological, Immunohistochemical, And Molecular Alterations In Brain Tissue And Submandibular Salivary Gland Of Atrazine-Induced Toxicity In Male Rats

  2022cites this paper
• Bisphenol A exposure induces testicular oxidative damage via FTO/m6A/Nrf2 axis during postnatal development in mice

  2022cites this paper
• Oocyte Development and Quality in Young and Old Mice following Exposure to Atrazine

  2022cites this paper
• Atrazine-induced oxidative damage via modulating xenobiotic-sensing nuclear receptors and cytochrome P450 systems in cerebrum and antagonism of lycopene.

  2022cites this paper
• Dietary myricetin assuages atrazine-mediated hypothalamic-pituitary–testicular axis dysfunction in rats

  2022cites this paper
• First report on atrazine monitoring in drinking water from Ijebu-North, South-West Nigeria: Human health risk evaluation and reproductive toxicity studies

  2022influential citation
• Reduced oocyte quality and exacerbation of the maternal age effect are enduring consequences of low-level atrazine exposure in mouse

  2022cites this paper
• Meta-analysis and experimental validation identified atrazine as a toxicant in the male reproductive system

  2021cites this paper
• Sustainable Agriculture Reviews 48: Pesticide Occurrence, Analysis and Remediation Vol. 2 Analysis

  2021cites this paper
• New evidence for deleterious effects of environmental contaminants on the male gamete.

  2021cites this paper
• Atrazine neural and reproductive toxicity

  2021cites this paper
• Pesticides in Drinking Water and Removal Techniques

  2021cites this paper
• Chronic stress affects tyrosine phosphorylated protein expression and secretion of male rat epididymis

  2021cites this paper
• Atrazine impairs testicular function in BalB/c mice by affecting Leydig cells.

  2021cites this paper
• Gallic acid ameliorates busulfan-induced testicular toxicity and damage in mature rats

  2021cites this paper
• Effects of a mixture of low doses of atrazine and benzo[a]pyrene on the rat seminiferous epithelium either during or after the establishment of the blood-testis barrier in the rat seminiferous tubule culture model.

  2020cites this paper
• Long-term maternal exposure to atrazine in the drinking water reduces penis length in the tammar wallaby Macropus eugenii

  2020cites this paper
• Chronic Atrazine Exposure Beginning Prenatally Impacts Liver Function and Sperm Concentration With Multi-Generational Consequences in Mice

  2020cites this paper
• Pesticides Usage, Uptake and Mode of Action in Plants with Special Emphasis on Photosynthetic Characteristics

  2020cites this paper
• The protective effect of fluted pumpkin seeds against atrazine-induced testicular injury

  2020cites this paper
• Effect of Anthocleista djalonensis A. Chev Root Extract on Testis of Matured Rats

  2020cites this paper
• Mutagenic, genotoxic and morphotoxic potential of different pesticides in the erythrocytes of Podocnemis expansa neonates.

  2020cites this paper
• Modeling and Prioritizing Interventions Using Pollution Hotspots for Reducing Nutrients, Atrazine and E. coli Concentrations in a Watershed

  2020cites this paper
• Occurrence and Removal of Pesticides in Drinking Water

  2020cites this paper
• Effect of environmental contamination on female and male gametes – A lesson from bovines

  2020cites this paper
• The MEK/ERK/CREB signaling pathway is involved in atrazine induced hippocampal neurotoxicity in Sprague Dawley rats.

  2019cites this paper
• Effect of γ-oryzanol on testicular degeneration induced by scrotal insulation in rams.

  2019cites this paper
• Atrazine exposure in gestation and breastfeeding affects Calomys laucha sperm cells

  2019cites this paper
• Atrazine-induced toxicity in goat spermatozoa is alleviated to some extent by polyphenol-enriched feed.

  2019cites this paper
• Food Hazards: Physical, Chemical, and Biological

  2019cites this paper
• Dietary fluted pumpkin seeds induce reversible oligospermia and androgen insufficiency in adult rats

  2019cites this paper
• Effets de l’extrait aqueux des écorces de tronc de pausinystalia yohimbe sur la qualité de la semence et les performances de reproduction chez le rat mâle wistar

  2019cites this paper
• Exposure to atrazine during puberty reduces sperm viability, increases weight gain and alters the expression of key metabolic genes in the liver of male mice.

  2019cites this paper
• Atrazine Triggers Mitochondrial Dysfunction and Oxidative Stress in Quail ( Coturnix C. coturnix) Cerebrum via Activating Xenobiotic-Sensing Nuclear Receptors and Modulating Cytochrome P450 Systems.

  2018cites this paper
• Celecoxib, a cyclooxygenase-2 inhibitor, offers chemoprevention against reproductive and neurobehavioural abnormalities induced by atrazine in male Wistar rats.

  2018cites this paper
• The herbicide atrazine affects sperm quality and the expression of antioxidant and spermatogenesis genes in zebrafish testes.

  2018cites this paper
• Changes in hepatic phase I and phase II biotransformation enzyme expression and glutathione levels following atrazine exposure in female rats

  2018cites this paper
• Dose- dependent ameliorative effects of quercetin and l-Carnitine against atrazine- induced reproductive toxicity in adult male Albino rats.

  2018cites this paper
• Telfairia occidentalis‐supplemented diet induces changes in sperm parameters and testosterone level in rats

  2018cites this paper
• Oxidative stress in triazine pesticide toxicity: a review of the main biomarker findings

  2018cites this paper
• Developmental Exposure to Atrazine Impairs Spatial Memory and Downregulates the Hippocampal D1 Dopamine Receptor and cAMP-Dependent Signaling Pathway in Rats

  2018cites this paper
• LC3-II may mediate ATR-induced mitophagy in dopaminergic neurons through SQSTM1/p62 pathway

  2018cites this paper
• Endocrine disruption and chronic effects of plant protection products in bees: Can we better protect our pollinators?

  2018cites this paper
• Ameliorative potential of Betulinic Acid against Atrazine-induced Hepatic and Testicular Damage in Wistar rats

  2018cites this paper
• Early exposure to atrazine in zebrafish: intergenerational effects and animal personality

  2018cites this paper
• Green Tea Protects Testes against Atrazine-induced Toxicity in Rat

  2017cites this paper
• Embryonic exposure to the widely-used herbicide atrazine disrupts meiosis and normal follicle formation in female mice

  2017cites this paper
• Oxidative stress affects sperm performance and ejaculate redox status in subordinate house sparrows

  2017cites this paper
• Rutin, an antioxidant flavonoid, induces glutathione and glutathione peroxidase activities to protect against ethanol effects in cadmium‐induced oxidative stress in the testis of adult rats

  2017cites this paper
• Use of job-exposure matrices to estimate occupational exposure to pesticides: A review

  2017cites this paper
• Hepatotoxic and nephrotoxic effects of atrazine on adult male xenopus laevis frogs: a laboratory study

  2017cites this paper
• Co-Administration of Vitamin E and Testosterone Attenuates The Atrazine-Induced Toxic Effects on Sperm Quality and Testes in Rats

  2017cites this paper
• Low atrazine dosages reduce sperm quality of Calomys laucha mice

  2017influential citation
• Effects of co-exposure to atrazine and ethanol on the oxidative damage of kidney and liver in Wistar rats

  2017cites this paper
• Effect of the herbicide atrazine and its metabolite DACT on bovine sperm quality.

  2017cites this paper
• THIOBENCARB DECREASES TESTICULAR GERM CELL PROLIFERATION, INHIBITS SPERMATOGENESIS AND INCREASES APOPTOSIS: HISTOLOGICAL AND IMMUNOHISTOCHEMICAL ASSESSMENTS

  2017cites this paper
• Effect of Fenugreek Seed Extract on Some Haematological and Biochemical Parameters in Atrazine Treated Male Rats

  2017cites this paper