Modeling schizophrenia using induced pluripotent stem cell-derived and fibroblast-induced neurons.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Schizophrenia bulletin

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1093/schbul/sbs127PMID 23172000PMCID PMC3523925
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

  2012cited by this paper
• Direct conversion of fibroblasts into stably expandable neural stem cells.

  2012cited by this paper
• Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor.

  2012cited by this paper
• Induction of pluripotent stem cell cells from germ cells

  2012cited by this paper
• Altered Oxygen Metabolism Associated to Neurogenesis of Induced Pluripotent Stem Cells Derived from a Schizophrenic Patient

  2012cited by this paper
• Direct conversion of dermal fibroblasts into neural progenitor cells by a novel cocktail of defined factors.

  2012cited by this paper
• Modeling human cortical development in vitro using induced pluripotent stem cells

  2012cited by this paper
• Zic3 induces conversion of human fibroblasts to stable neural progenitor-like cells.

  2012cited by this paper
• Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses

  2012cited by this paper
• Floor plate-derived dopamine neurons from hESCs efficiently engraft in animal models of PD

  2011cited by this paper
• Functional integration of dopaminergic neurons directly converted from mouse fibroblasts.

  2011cited by this paper
• Direct generation of functional dopaminergic neurons from mouse and human fibroblasts

  2011cited by this paper
• Modelling schizophrenia using human induced pluripotent stem cells

  2011cited by this paper
• Modelling schizophrenia using human induced pluripotent stem cells

  2011cited by this paper
• Induction of human neuronal cells by defined transcription factors

  2011cited by this paper
• MicroRNA-mediated conversion of human fibroblasts to neurons

  2011cited by this paper
• Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions.

  2011cited by this paper
• Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

  2011cited by this paper
• Integration-free induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation

  2011cited by this paper
• Neuregulin 1 Promotes Excitatory Synapse Development and Function in GABAergic Interneurons

  2011cited by this paper
• A more efficient method to generate integration-free human iPS cells

  2011cited by this paper
• Direct conversion of fibroblasts to functional neurons by defined factors

  2010cited by this paper
• Development of Defective and Persistent Sendai Virus Vector

  2010cited by this paper
• Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

  2010cited by this paper
• A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells.

  2010cited by this paper
• Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

  2009cited by this paper
• Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons

  2009cited by this paper
• Induced pluripotent stem cells generated without viral integration

  2009cited by this paper
• Dopamine D2 receptor levels in striatum, thalamus, substantia nigra, limbic regions, and cortex in schizophrenic subjects.

  2009cited by this paper
• Induced Pluripotent Stem Cells Generated Without Viral Integration

  2008cited by this paper
• Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

  2008cited by this paper
• Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

  2008cited by this paper
• A high-efficiency system for the generation and study of human induced pluripotent stem cells.

  2008cited by this paper
• Disease-specific induced pluripotent stem cells.

  2008cited by this paper
• Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

  2007cited by this paper
• Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

  2007cited by this paper
• Induction of pluripotent stem cells from fibroblast cultures

  2007cited by this paper
• Generation of germline-competent induced pluripotent stem cells

  2007cited by this paper
• Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

  2007cited by this paper
• Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

  2006cited by this paper
• Specification of motoneurons from human embryonic stem cells

  2005cited by this paper
• Directed differentiation of telencephalic precursors from embryonic stem cells

  2005cited by this paper
• Directed differentiation of telencephalic precursors from embryonic stem cells

  2005cited by this paper
• Derivation of midbrain dopamine neurons from human embryonic stem cells.

  2004cited by this paper
• Directed differentiation of embryonic stem cells into motor neurons.

  2002cited by this paper
• Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.

  2000cited by this paper
• Neurotechnique Induction of Midbrain Dopaminergic Neurons from ES Cells by Stromal Cell-Derived Inducing Activity

  2000cited by this paper
• Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.

  1994cited by this paper
• Implications of normal brain development for the pathogenesis of schizophrenia.

  1988cited by this paper
• Implications of normal brain development for the pathogenesis of schizophrenia.

  1987cited by this paper

• Exploring the roots of schizophrenia: Current research and future directions (Review).

  2026influential citation
• Impaired migration of autologous induced neural stem cells from patients with schizophrenia and implications for genetic risk for psychosis.

  2022cites this paper
• Enhanced efficiency of nonviral direct neuronal reprogramming on topographical patterns.

  2021cites this paper
• Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia.

  2021cites this paper
• Cellular Models in Schizophrenia Research

  2021cites this paper
• Schizophrenia; Recent Cognitive and Treatment Approaches Using Induced Pluripotent Stem Cells

  2020cites this paper
• Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: potential attenuating effects on recruitment of regulatory T cells.

  2020cites this paper
• A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia

  2020cites this paper
• Engineering three-dimensional microenvironments towards in vitro disease models of the central nervous system

  2019cites this paper
• A tale of two families: neural precursor cells from idiopathic autism patients exhibit proliferation phenotypes

  2018cites this paper
• Induced Pluripotent Stem Cells: Global Research Trends

  2017cites this paper
• Functional Consequences of CHRNA7 Copy-Number Alterations in Induced Pluripotent Stem Cells and Neural Progenitor Cells.

  2017cites this paper
• Investigation of Gene Splicing Variants Contributing Risk to Psychiatric Disorders

  2017cites this paper
• Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds

  2016cites this paper
• Are reprogrammed cells a useful tool for studying dopamine dysfunction in psychotic disorders? A review of the current evidence

  2016cites this paper
• Characterization of Genetic Networks Associated with Alzheimer's Disease.

  2016cites this paper
• Metabolic stress and antipsychotic treatment induced gene expression alterations in human cell cultures

  2016influential citation
• Induced Pluripotent Stem Cells as a Novel Tool in Psychiatric Research

  2015cites this paper
• Engineered in vitro disease models.

  2015cites this paper
• GABA(A) receptor trafficking and localization in schizophrenia

  2015cites this paper
• A Dishful of a Troubled Mind: Induced Pluripotent Stem Cells in Psychiatric Research

  2015influential citation
• Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18–24 Months

  2015cites this paper
• RNA Sequencing in Schizophrenia

  2015cites this paper
• Stem Cells on the Brain: Modeling Neurodevelopmental and Neurodegenerative Diseases Using Human Induced Pluripotent Stem Cells

  2014cites this paper
• Biomarkers for combat-related PTSD: focus on molecular networks from high-dimensional data

  2014cites this paper
• Unlocking the treasure trove: from genes to schizophrenia biology.

  2014cites this paper
• The human side of microglia.

  2014cites this paper
• Engineered synthetic microenvironments for human pluripotent stem cells: applications for neuronal regeneration

  2013cites this paper
• Will brain cells derived from induced pluripotent stem cells or directly converted from somatic cells (iNs) be useful for schizophrenia research?

  2013cites this paper