Structure, function and evolution of seryl-tRNA synthetases: Implications for the evolution of aminoacyl-tRNA synthetases and the genetic code

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Journal of Molecular Evolution

• Publication date

  1995-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF00166620PMID 7540217
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progressive sequence alignment as a prerequisitetto correct phylogenetic trees

  2007cited by this paper
• The origin of polynucleotide-directed protein synthesis

  2007cited by this paper
• Metabolic complexity in the RNA world and implications for the origin of protein synthesis

  2005cited by this paper
• 2 Prospects for Understanding the Origin of the RNA World

  1999cited by this paper
• The structural basis for seryl-adenylate and Ap4A synthesis by seryl-tRNA synthetase.

  1995cited by this paper
• Aminoacyl-RNA synthesis catalyzed by an RNA

  1995cited by this paper
• The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli.

  1995cited by this paper
• Coexpression of eukaryotic tRNASer and yeast seryl-tRNA synthetase leads to functional amber suppression in Escherichia coli

  1994cited by this paper
• The 2.9 A crystal structure of T. thermophilus seryl-tRNA synthetase complexed with tRNA(Ser).

  1994cited by this paper
• Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.

  1994cited by this paper
• The transfer RNA identity problem: a search for rules.

  1994cited by this paper
• The exchange of the discriminator base A73 for G is alone sufficient to convert human tRNA(Leu) into a serine‐acceptor in vitro.

  1994cited by this paper
• The active site of yeast aspartyl‐tRNA synthetase: structural and functional aspects of the aminoacylation reaction.

  1994cited by this paper
• Fitting the structurally diverse animal mitochondrial tRNAs(Ser) to common three-dimensional constraints.

  1994cited by this paper
• An RNA pocket for an aliphatic hydrophobe

  1994cited by this paper
• Seryl-tRNA synthetase from Escherichia coli: implication of its N-terminal domain in aminoacylation activity and specificity.

  1994cited by this paper
• The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.

  1994cited by this paper
• Crystal structure of a prokaryotic aspartyl tRNA‐synthetase.

  1994cited by this paper
• Escherichia coli seryl-tRNA synthetase recognizes tRNA(Ser) by its characteristic tertiary structure.

  1994cited by this paper
• A tale of two synthetases

  1994cited by this paper
• Solution structure of selenocysteine-inserting tRNA(Sec) from Escherichia coli. Comparison with canonical tRNA(Ser).

  1993cited by this paper
• Yeast tRNAAsp recognition by its cognate class II aminoacyl-tRNA synthetase

  1993cited by this paper
• An RNA motif that binds ATP

  1993cited by this paper
• Identity determinants of human tRNA(Ser): sequence elements necessary for serylation and maturation of a tRNA with a long extra arm.

  1993cited by this paper
• Yeast seryl-tRNA synthetase expressed in Escherichia coli recognizes bacterial serine-specific tRNAs in vivo.

  1993cited by this paper
• Phenylalanyl-tRNA synthetase from Thermus thermophilus has four antiparallel folds of which only two are catalytically functional.

  1993influential reference
• Recognition nucleotides of Escherichia coli tRNA(Leu) and its elements facilitating discrimination from tRNASer and tRNA(Tyr).

  1993cited by this paper
• Contributions of discrete tRNA(Ser) domains to aminoacylation by E.coli seryl-tRNA synthetase: a kinetic analysis using model RNA substrates.

  1993cited by this paper
• Sequence, structure and evolutionary relationships between class 2 aminoacyl-tRNA synthetases: an update.

  1993cited by this paper
• The long extra arms of human tRNA((Ser)Sec) and tRNA(Ser) function as major identify elements for serylation in an orientation-dependent, but not sequence-specific manner.

  1993cited by this paper
• OB(oligonucleotide/oligosaccharide binding)‐fold: common structural and functional solution for non‐homologous sequences.

  1993cited by this paper
• Refined crystal structure of the seryl-tRNA synthetase from Thermus thermophilus at 2.5 A resolution.

  1993cited by this paper
• The aminoacyl‐tRNA synthetase family: Modules at work

  1993cited by this paper
• Crystallization of the seryl‐tRNA synthetase: tRNAser complex of Escherichia coli

  1993cited by this paper
• An operational RNA code for amino acids and possible relationship to genetic code.

  1993cited by this paper
• THE AMINOACYL-tRNA SYNTHETASE FAMILY: AN EVOLUTIONARY VIEW OF THEIR STRUCTURAL ORGANIZATION

  1993cited by this paper
• 1 Prospects for Understanding the Origin of the RNA World

  1993cited by this paper
• 2 Reading the Palimpsest: Contemporary Biochemical Data and the RNA World

  1993cited by this paper
• Single pass sequencing and physical and genetic mapping of human brain cDNAs

  1992cited by this paper
• Aminoacyl esterase activity of the Tetrahymena ribozyme.

  1992cited by this paper
• Serine tRNA complementary to the nonuniversal serine codon CUG in Candida cylindracea: evolutionary implications.

  1992cited by this paper
• Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.

  1992cited by this paper
• A Recognition Model of tRNASer by Seryl-tRNA Synthetase in E. coli.

  1992cited by this paper
• The T-loop region of animal mitochondrial tRNA(Ser)(AGY) is a main recognition site for homologous seryl-tRNA synthetase.

  1992cited by this paper
• A seryl-tRNA synthetase gene is coamplified with the adenylate deaminase 2 gene in coformycin resistant Chinese hamster fibroblasts.

  1992cited by this paper
• Eight base changes are sufficient to convert a leucine-inserting tRNA into a serine-inserting tRNA.

  1992cited by this paper
• Unusual resistance of peptidyl transferase to protein extraction procedures.

  1992cited by this paper
• Sequence, structural and evolutionary relationships between class 2 aminoacyl-tRNA synthetases

  1991cited by this paper
• Selenocysteine: the 21st amino acid

  1991cited by this paper
• The length of the aminoacyl-acceptor stem of the selenocysteine-specific tRNA(Sec) of Escherichia coli is the determinant for binding to elongation factors SELB or Tu.

  1991cited by this paper
• Recognition of tRNAs by aminoacyl-tRNA synthetases.

  1991cited by this paper
• Class II aminoacyl transfer RNA synthetases: crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp)

  1991cited by this paper
• Mammalian seryl-tRNA synthetase associates with mRNA in vivo and has homology to elongation factor 1 alpha.

  1991cited by this paper
• Immuno‐chemical non‐cross‐reactivity between eukaryotic and prokaryotic seryl‐tRNA synthetases

  1991cited by this paper
• Unilateral aminoacylation specificity between bovine mitochondria and eubacteria.

  1991cited by this paper
• Conversion of aminoacylation specificity from tRNA(Tyr) to tRNA(Ser) in vitro.

  1990cited by this paper
• A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 Å

  1990cited by this paper
• Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs

  1990cited by this paper
• The contacts of yeast tRNA(Ser) with seryl-tRNA synthetase studied by footprinting experiments.

  1990cited by this paper
• Specificity of arginine binding by the Tetrahymena intron.

  1989cited by this paper
• Solution structure of a tRNA with a large variable region: yeast tRNASer.

  1989cited by this paper
• Modern metabolism as a palimpsest of the RNA world.

  1989cited by this paper
• The codon CUG is read as serine in an asporogenic yeast Candida cylindracea

  1989cited by this paper
• Genetic code development by stop codon takeover.

  1988cited by this paper
• RNA world

  1987cited by this paper
• Cloning and characterization of the gene for Escherichia coli seryl-tRNA synthetase.

  1987cited by this paper
• Cloning and characterization of the gene coding for cytoplasmic seryl-tRNA synthetase from Saccharomyces cerevisiae.

  1987cited by this paper
• Origin of life: The RNA world

  1986cited by this paper
• Changing the identity of a transfer RNA

  1986cited by this paper
• Origin of the genetic code: a testable hypothesis based on tRNA structure, sequence, and kinetic proofreading.

  1978cited by this paper
• Speculations on the evolution of the genetic code II

  1978cited by this paper
• Aminoacyl-tRNA synthetase families and their significance to the origin of the genetic code

  1978cited by this paper
• Speculations on the evolution of the genetic code

  1975cited by this paper
• Nucleotide sequences of rat liver serine-tRNA. 1. Products of digestion with pancreatic ribonuclease.

  1971cited by this paper
• Evolving Genes and Proteins.

  1965cited by this paper
• See Blockindiscussions, Blockinstats, Blockinand Blockinauthor Blockinprofiles Blockinfor Blockinthis Blockinpublication Clustal: Blockina Blockinpackage Blockinfor Blockinperforming Multiple Blockinsequence Blockinalignment Blockinon Blockina Minicomputer Article Blockin Blockinin Blockin

  year unknowncited by this paper

• The Role of SARS1 in Head and Neck Squamous Cell Carcinoma and its Potential as a Diagnostic and Prognostic Biomarker

  2025influential citation
• Recognition and catalytic mechanism of tRNA m3C methyltransferase METTL6

  2025cites this paper
• Three Biopolymers and Origin of Life Scenarios

  2024cites this paper
• Protein–Protein Interactions of Seryl-tRNA Synthetases with Emphasis on Human Counterparts and Their Connection to Health and Disease

  2024cites this paper
• Motor skill learning modulates striatal extracellular vesicles’ content in a mouse model of Huntington’s disease

  2024cites this paper
• Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase

  2023cites this paper
• Amino Acid Specificity of Ancestral Aminoacyl-tRNA Synthetase Prior to the Last Universal Common Ancestor Commonote commonote

  2022influential citation
• Amino Acid Specificity of Ancestral Aminoacyl-tRNA Synthetase Prior to the Last Universal Common Ancestor Commonote commonote

  2022cites this paper
• An Evolutionary Perspective on the Origin, Conservation and Binding Partner Acquisition of Tankyrases

  2022cites this paper
• Seryl-tRNA synthetase specificity for tRNASec in Bacterial Sec biosynthesis.

  2020cites this paper
• Characterization of Amino Acid Recognition in Aminoacyl-tRNA Synthetases

  2019cites this paper
• The structural basis of the genetic code: amino acid recognition by aminoacyl-tRNA synthetases

  2019cites this paper
• Structural evolution of Glycyl-tRNA synthetases alpha subunit and its implication in the initial organization of the decoding system.

  2019cites this paper
• The unique tRNASec and its role in selenocysteine biosynthesis

  2018cites this paper
• Coding of Class I and II Aminoacyl-tRNA Synthetases.

  2017cites this paper
• Investigating β-N-Methylamino-l-alanine Misincorporation in Human Cell Cultures: A Comparative Study with Known Amino Acid Analogues

  2017cites this paper
• Protein Reviews

  2017cites this paper
• Exclusive cytosolic localization and broad tRNASer specificity of Arabidopsis thaliana seryl-tRNA synthetase

  2016cites this paper
• What RNA World? Why a Peptide/RNA Partnership Merits Renewed Experimental Attention

  2015cites this paper
• Ancestral Reconstruction of a Pre-LUCA Aminoacyl-tRNA Synthetase Ancestor Supports the Late Addition of Trp to the Genetic Code

  2015cites this paper
• Functional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same Gene*

  2015cites this paper
• Towards Sense Codon Reassignment in Escherichia Coli

  2015cites this paper
• The N‐terminal fragment of Acanthamoeba polyphaga mimivirus tyrosyl‐tRNA synthetase (TyrRSapm) is a monomer in solution

  2013cites this paper
• Aminoacylating Urzymes Challenge the RNA World Hypothesis*♦

  2013cites this paper
• Structural Investigation Of Atp-Utilizing Enzymes: Structures Involved In H+ Homeostasis And The Proliferation Of Hormone-Dependent Cancers

  2010cites this paper
• Insights into the function of short interspersed degenerated retroposons in the protozoan parasite Leishmania

  2008cites this paper
• Signature of a Primitive Genetic Code in Ancient Protein Lineages

  2007cites this paper
• Shuffling of discrete tRNASer regions reveals differently utilized identity elements in yeast and methanogenic archaea.

  2006cites this paper
• The unusual methanogenic seryl-tRNA synthetase recognizes tRNASer species from all three kingdoms of life.

  2004cites this paper
• On the 28-gon symmetry inherent in the genetic code intertwined with aminoacyl-tRNA synthetases—The Lucas series

  2004cites this paper
• On the Classes of Aminoacyl-tRNA Synthetases, Amino Acids and the Genetic Code

  2004cites this paper
• Maize seryl-tRNA synthetase: specificity of substrate recognition by the organellar enzyme.

  2002cites this paper
• Characterization and tRNA Recognition of Mammalian Mitochondrial Seryl-tRNA Synthetase*

  2000cites this paper
• Correlating amino acid conservation with function in tyrosyl-tRNA synthetase.

  2000cites this paper
• Archaeabacterial Seryl-tRNA Synthetases: Adaptation to Extreme Environments and Evolutionary Analysis

  1999cites this paper
• Unique recognition style of tRNA(Leu) by Haloferax volcanii leucyl-tRNA synthetase.

  1999cites this paper
• tRNA recognition and evolution of determinants in seryl-tRNA synthesis.

  1999cites this paper
• tRNA(Pro) anticodon recognition by Thermus thermophilus prolyl-tRNA synthetase.

  1998cites this paper
• Maize mitochondrial seryl-tRNA synthetase recognizes Escherichia coli tRNASer in vivo and in vitro

  1998cites this paper
• ATP binding site of P2X channel proteins: structural similarities with class II aminoacyl‐tRNA synthetases

  1998cites this paper
• The Path from the RNA World

  1998cites this paper
• Cross-species aminoacylation of tRNA with a long variable arm between Escherichia coli and Saccharomyces cerevisiae.

  1998cites this paper
• C‐terminal truncation of yeast SerRS is toxic for Saccharomyces cerevisiae due to altered mechanism of substrate recognition

  1998cites this paper
• Evolutionary anomalies among the aminoacyl-tRNA synthetases.

  1998cites this paper
• Aminoacyl-tRNA synthetases in biology and disease: new evidence for structural and functional diversity in an ancient family of enzymes.

  1997cites this paper
• Detection of Noncovalent tRNA·Aminoacyl-tRNA Synthetase Complexes by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry*

  1997cites this paper
• Defining the Active Site of Yeast Seryl-tRNA Synthetase

  1997cites this paper
• Only one nucleotide insertion to the long variable arm confers an efficient serine acceptor activity upon Saccharomyces cerevisiae tRNA(Leu) in vitro.

  1997cites this paper
• The crystal structure of the ternary complex of T.thermophilus seryl‐tRNA synthetase with tRNA(Ser) and a seryl‐adenylate analogue reveals a conformational switch in the active site.

  1996cites this paper
• Translocation events in the evolution of aminoacyl-tRNA synthetases.

  1996cites this paper
• Partition of aminoacyl-tRNA synthetases in two different structural classes dating back to early metabolism: Implications for the origin of the genetic code and the nature of protein sequences

  1995cites this paper