Sequence, structural and evolutionary relationships between class 2 aminoacyl-tRNA synthetases

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Nucleic Acids Res.

• Publication date

  1991-07-11

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1093/nar/19.13.3489PMID 1852601PMCID PMC328370
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structure and evolution of a group of related aminoacyl-tRNA synthetases.

  1991cited by this paper
• Tyr‐426 of the Escherichia coli asparaginyl‐tRNA synthetase, an amino acid in a C‐terminal concerved motif, is involved in ATP binding

  1991cited by this paper
• Cysteinyl-tRNA synthetase: determination of the last E. coli aminoacyl-tRNA synthetase primary structure.

  1991cited by this paper
• Homology of lysS and lysU, the two Escherichia coli genes encoding distinct lysyl-tRNA synthetase species.

  1990cited by this paper
• Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs

  1990cited by this paper
• Crystallographic study at 2.5 A resolution of the interaction of methionyl-tRNA synthetase from Escherichia coli with ATP.

  1990cited by this paper
• Independent genes for two threonyl-tRNA synthetases in Bacillus subtilis

  1990cited by this paper
• Escherichia coli threonyl-tRNA synthetase and tRNA(Thr) modulate the binding of the ribosome to the translational initiation site of the thrS mRNA.

  1990cited by this paper
• Primary structure of alanyl-tRNA synthetase and the regulation of its mRNA levels in Bombyx mori.

  1990cited by this paper
• Understanding structural relationships proteins of unsolved three‐dimensional structure

  1990cited by this paper
• A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 Å

  1990cited by this paper
• Aspartyl-tRNA synthetase from Escherichia coli: cloning and characterisation of the gene, homologies of its translated amino acid sequence with asparaginyl- and lysyl-tRNA synthetases.

  1990cited by this paper
• Identification of a novel translation factor necessary for the incorporation of selenocysteine into protein

  1989cited by this paper
• Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8 A resolution.

  1989cited by this paper
• cDNA sequence, predicted primary structure, and evolving amphiphilic helix of human aspartyl-tRNA synthetase.

  1989cited by this paper
• Homology of aspartyl- and lysyl-tRNA synthetases.

  1989cited by this paper
• Asparaginyl-tRNA synthetase from Escherichia coli has significant sequence homologies with yeast aspartyl-tRNA synthetase.

  1989cited by this paper
• Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.

  1989cited by this paper
• tRNA‐like structures and gene regulation at the translational level: a case of molecular mimicry in Escherichia coli.

  1989cited by this paper
• Gene for a novel tRNA species that accepts L-serine and cotranslationally inserts selenocysteine

  1988cited by this paper
• Cloning and characterization of a potentially protective antigen in lymphatic filariasis.

  1988cited by this paper
• Messenger RNA structure and gene regulation at the translational level in Escherichia coli: the case of threonine:tRNAThr ligase.

  1988cited by this paper
• The yeast lysyl-tRNA synthetase gene. Evidence for general amino acid control of its expression and domain structure of the encoded protein.

  1988cited by this paper
• Structure and expression of the genes encoding the alpha and beta subunits of yeast phenylalanyl-tRNA synthetase.

  1988cited by this paper
• Isolation and characterization of the yeast gene coding for the alpha subunit of mitochondrial phenylalanyl-tRNA synthetase.

  1987cited by this paper
• FEBS Letters

  1987cited by this paper
• Isolation, structure and expression of mammalian genes for histidyl-tRNA synthetase.

  1987cited by this paper
• tRNA-like structures tag the 3' ends of genomic RNA molecules for replication: implications for the origin of protein synthesis.

  1987cited by this paper
• Cloning and characterization of the gene coding for cytoplasmic seryl-tRNA synthetase from Saccharomyces cerevisiae.

  1987cited by this paper
• Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis.

  1987cited by this paper
• Proteins

  1987cited by this paper
• Cloning and characterization of the gene for Escherichia coli seryl-tRNA synthetase.

  1987cited by this paper
• Nucleotide sequence of the gene coding for yeast cytoplasmic aspartyl-tRNA synthetase (APS); mapping of the 5' and 3' termini of AspRS mRNA.

  1986cited by this paper
• Sequence similarities among the family of aminoacyl-tRNA synthetases.

  1986cited by this paper
• The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae.

  1986cited by this paper
• Primary structure of histidine-tRNA synthetase and characterization of hisS transcripts.

  1985cited by this paper
• Cloning and characterization of the gene for the yeast cytoplasmic threonyl-tRNA synthetase.

  1985cited by this paper
• Sequence of the Escherichia coli pheST operon and identification of the himA gene

  1985cited by this paper
• Characterization of a yeast nuclear gene (MST1) coding for the mitochondrial threonyl-tRNA1 synthetase.

  1985cited by this paper
• Primary structures of both subunits of Escherichia coli glycyl-tRNA synthetase.

  1983cited by this paper
• Structural and transcriptional evidence for related thrS and infC expression.

  1983cited by this paper
• Establishing homologies in protein sequences.

  1983cited by this paper
• Purification and properties of alanine tRNA synthetase from Escherichia coli A tetramer of identical subunits.

  1981cited by this paper
• A co-evolution theory of the genetic code.

  1975cited by this paper
• Amino acids are not all initially attached to the same position on transfer RNA molecules.

  1975cited by this paper
• Site of aminoacylation of tRNAs from Escherichia coli with respect to the 2'- or 3'-hydroxyl group of the terminal adenosine.

  1975cited by this paper
• The Enzymes

  1961cited by this paper

• Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase

  2025cites this paper
• Architecture of Pseudomonas aeruginosa glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases

  2025cites this paper
• AARS1 and AARS2: From Protein Synthesis to Lactylation-Driven Oncogenesis

  2025cites this paper
• Protein–Protein Interactions of Seryl-tRNA Synthetases with Emphasis on Human Counterparts and Their Connection to Health and Disease

  2024cites this paper
• Structural basis for aminoacylation of cellular modified tRNALys3 by human lysyl-tRNA synthetase

  2024cites this paper
• Mechanism of tRNA recognition by heterotetrameric glycyl-tRNA synthetase from lactic acid bacteria

  2023cites this paper
• Exploration of seryl tRNA synthetase to identify potent inhibitors against leishmanial parasites.

  2023cites this paper
• Sequential magnesium binding facilitates lysyl-tRNA synthetase to recognize ATP

  2023cites this paper
• Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation

  2023cites this paper
• Coding From Binding? Molecular Interactions at the Heart of Translation.

  2022cites this paper
• Structural Computational Analysis of the Natural History of Class I aminoacyl-tRNA Synthetases Suggests their Role in Establishing the Genetic Code

  2021cites this paper
• Proteomic profiling of salmonella under berberine stress

  2020cites this paper
• An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli.

  2020cites this paper
• Trans-editing by aminoacyl-tRNA synthetase-like editing domains.

  2020cites this paper
• Structures and functions of multi-tRNA synthetase complexes.

  2020cites this paper
• Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer

  2019cites this paper
• Conformational changes in glutaminyl-tRNA synthetases upon binding of the substrates and analogs using molecular docking and molecular dynamics approaches

  2019cites this paper
• Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Complex Via Interactions between Glutathione Transferase-Homology Domains and Aspartyl-tRNA Synthetase.

  2019cites this paper
• Truncated Non-Nuclear Transposable Elements in Grapevine: A Mini Review

  2019cites this paper
• Coding triplets in the transfer RNA arm and their role in present and past tRNA recognition

  2019cites this paper
• Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase

  2019cites this paper
• Structural and functional analysis of Glutaminyl-tRNA synthetase (TtGlnRS) from Thermus thermophilus HB8 and its complexes.

  2018cites this paper
• Backbone Brackets and Arginine Tweezers delineate Class I and Class II aminoacyl tRNA synthetases

  2018cites this paper
• Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.

  2018cites this paper
• Identification of Chemical Compounds That Inhibit the Function of Histidyl-tRNA Synthetase from Pseudomonas aeruginosa

  2018cites this paper
• Acceptor Stem Differences Contribute to Species-Specific Use of Yeast and Human tRNASer

  2018influential citation
• Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach.

  2017cites this paper
• Coding of Class I and II Aminoacyl-tRNA Synthetases.

  2017influential citation
• Clone and functional analysis of Seryl-tRNA synthetase and Tyrosyl-tRNA synthetase from silkworm, Bombyx mori

  2017cites this paper
• Protein Reviews

  2017cites this paper
• Enzymatic Post-Transfer Editing Mechanism of E. coli Threonyl-tRNA Synthetase (ThrRS): A Molecular Dynamics (MD) and Quantum Mechanics/Molecular Mechanics (QM/MM) Investigation

  2017cites this paper
• Natural products and their derivatives as tRNA synthetase inhibitors and antimicrobial agents

  2016cites this paper
• From the RNA world to the RNA/protein world: contribution of some riboswitch-binding species?

  2015cites this paper
• Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase

  2015cites this paper
• In silico based virtual screening and mixed mode QM/MM calculation identifies caffeine scaffold for designing potential inhibitors for tyrosyl tRNA synthetase of Mycobacterium tuberculosis

  2015cites this paper
• The phenotypic expression of mitochondrial tRNA-mutations can be modulated by either mitochondrial leucyl-tRNA synthetase or the C-terminal domain thereof

  2015cites this paper
• Assembly and function of macromolecular complexes for accurate tRNA aminoacylation in Helicobacter pylori

  2014cites this paper
• Structural and functional characterization of proteins of unknown function (Hp0495, Hp0100, and Hp1259) in Helicobacter pylori

  2014cites this paper
• The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells

  2014cites this paper
• Comparison of the Intrinsic Dynamics of Aminoacyl-tRNA Synthetases

  2014influential citation
• Guanidine Hydrochloride Mediated Denaturation of E. coli Alanyl-tRNA Synthetase: Identification of an Inactive Dimeric Intermediate

  2014cites this paper
• Protein-protein interactions and multi-component complexes of aminoacyl-tRNA synthetases.

  2014cites this paper
• Recognition of tRNAs with a long variable arm by aminoacyl-tRNA synthetases

  2013cites this paper
• Interdomain communication modulates the tRNA-dependent pre-transfer editing of leucyl-tRNA synthetase.

  2013cites this paper
• Structural Phylogenomics Retrodicts the Origin of the Genetic Code and Uncovers the Evolutionary Impact of Protein Flexibility

  2013cites this paper
• Crystal structure of human Seryl-tRNA synthetase and Ser-SA complex reveals a molecular lever specific to higher eukaryotes.

  2013cites this paper
• Role of Alarmones in The Protection of Escherichia coli Against Stress

  2012cites this paper
• Identificação e caracterização do papel da glutamil-tRNA sintetase na localização de proteínas cloroplásticas

  2012cites this paper
• Aminoacyl-tRNA synthetase inhibitors as antimicrobial agents: a patent review from 2006 till present

  2012cites this paper
• Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.

  2012cites this paper
• Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing

  2012cites this paper
• Unusual domain architecture of aminoacyl tRNA synthetases and their paralogs from Leishmania major

  2012cites this paper
• Performance of nondenaturing micro 2‐DE followed by third‐dimension SDS‐PAGE in the analysis of Escherichia coli soluble proteins

  2011cites this paper
• Rôle de la lysyl-ARNt synthétase mitochondriale humaine dans la réplication du VIH-1

  2011cites this paper
• LeuRS synthetase: a first-principles investigation of the water-mediated editing reaction.

  2011cites this paper
• Identificação e caracterização do papel da glutamil-tRNA sintetase na localização de proteínas cloroplásticas

  2011cites this paper
• Flexibility and communication within the structure of the Mycobacterium smegmatis methionyl‐tRNA synthetase

  2010cites this paper
• Generació d'un model de malaltia mitocondrial humana en "Drosophila melanogaster"

  2010cites this paper
• Molecular Docking Study of Aminoacyl-tRNA Synthetases with Ligand Molecules from Four Different Scaffolds

  2010cites this paper
• Cartographie structurale et fonctionnelle de la liaison entre la peptidyl-ARNt hydrolase et son substrat

  2010cites this paper
• Crystallization and preliminary X-ray diffraction analysis of human cytosolic seryl-tRNA synthetase.

  2010cites this paper
• Template-based structure prediction and molecular dynamics simulation study of two mammalian Aspartyl-tRNA synthetases.

  2010cites this paper
• Crystallization of Mycobacterium smegmatis methionyl-tRNA synthetase in the presence of methionine and adenosine.

  2009cites this paper
• Nucleotide Triplet Based Molecular Phylogeny of Class I and Class II Aminoacyl t-RNA Synthetase in Three Domain of Life Process: Bacteria, Archaea, and Eukarya

  2008cites this paper
• Inhibition of Methionyl-tRNA Synthetase by REP8839 and Effects of Resistance Mutations on Enzyme Activity

  2008cites this paper
• Aminoacyl-tRNA synthetase classes and groups in prokaryotes.

  2008cites this paper
• Geometry of nonbonded interactions involving planar groups in proteins.

  2007cites this paper
• The nuclear-encoded inteins of fungi.

  2007cites this paper
• In silico detection of tRNA sequence features characteristic to aminoacyl-tRNA synthetase class membership

  2007cites this paper
• Structure of the unusual seryl‐tRNA synthetase reveals a distinct zinc‐dependent mode of substrate recognition

  2006cites this paper
• Functional Divergence of a Unique C-terminal Domain of Leucyl-tRNA Synthetase to Accommodate Its Splicing and Aminoacylation Roles*

  2006cites this paper
• An asymmetric underlying rule in the assignment of codons: possible clue to a quick early evolution of the genetic code via successive binary choices.

  2006cites this paper
• Emergence of the universal genetic code imprinted in an RNA record

  2006cites this paper
• Loss of a Universal tRNA Feature

  2006cites this paper
• Evolutionary conservation of a functionally important backbone phosphate group critical for aminoacylation of histidine tRNAs.

  2006cites this paper
• The duality of LysU, a catalyst for both Ap4A and Ap3A formation

  2006cites this paper
• Loss of Editing Activity during the Evolution of Mitochondrial Phenylalanyl-tRNA Synthetase*

  2005cites this paper
• Evolution of the tRNA(Tyr)/TyrRS aminoacylation systems.

  2005cites this paper
• Autoantibodies to aminoacyl-tRNA synthetases.

  2005cites this paper
• Stationary‐phase expression and aminoacylation of a transfer‐RNA‐like small RNA

  2005cites this paper
• Ability of Wild-Type and Mutant Lysyl-tRNA Synthetase To Facilitate tRNALys Incorporation into Human Immunodeficiency Virus Type 1

  2004cites this paper
• The selective packaging and annealing of primer tRNALys3 in HIV-1.

  2004cites this paper
• Regulation of Serine, Glycine, and One-Carbon Biosynthesis

  2004cites this paper
• Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.

  2004cites this paper
• Relationship of two human tRNA synthetases used in cell signaling.

  2004cites this paper
• The tRNALys packaging complex in HIV-1.

  2004cites this paper
• Aminoacyl-tRNA synthetase complexes: beyond translation

  2004cites this paper
• A structural study for the optimisation of functional motifs encoded in protein sequences

  2004cites this paper
• On the Evolution of Structure in Aminoacyl-tRNA Synthetases

  2003cites this paper
• Molecular network and functional implications of macromolecular tRNA synthetase complex.

  2003cites this paper
• Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.

  2003cites this paper
• GRS1, a Yeast tRNA Synthetase with a Role in mRNA 3′ End Formation*

  2003cites this paper
• Aminoacyl tRNA Synthetases

  2002cites this paper
• Structure and function of the C-terminal domain of methionyl-tRNA synthetase.

  2002cites this paper
• Leucyl-tRNA Synthetase Consisting of Two Subunits from Hyperthermophilic Bacteria Aquifex aeolicus *

  2002cites this paper
• Seryl‐tRNA synthetase is not responsible for the evolution of CUG codon reassignment in Candida albicans

  2001cites this paper
• On the Relative Content of G,C Bases in Codons of Amino Acids Corresponding to Class I and II Aminoacyl-tRNA Synthetases

  2001cites this paper
• A 6940 bp DNA Fragment from Desulfovibrio gigas Contains Genes Coding for Lipoproteins, Universal Stress Response and Transcriptional Regulator Protein Homologues

  2001cites this paper
• Aminoacyl-tRNA synthétases et tRNA : études fonctionnelles, structurales et génétiques d'une famille de molécules essentielles pour l'expression du code génétique.

  2001cites this paper
• Regulation of translation initiation by amino acids in eukaryotic cells.

  2001cites this paper