Daxx : from nuclear structure to protein function

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  2008

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• Regulation of c-met expression by transcription repressor Daxx

  2008cited by this paper
• Physical Interactions and Functional Coupling between Daxx and Sodium Hydrogen Exchanger 1 in Ischemic Cell Death*

  2008cited by this paper
• Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death‐associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by α‐lipoic acid

  2007cited by this paper
• Daxx Shortens Mitotic Arrest Caused by Paclitaxel

  2007cited by this paper
• Daxx mediates SUMO-dependent transcriptional control and subnuclear compartmentalization.

  2007cited by this paper
• Inhibition of NF-kappaB acetylation and its transcriptional activity by Daxx.

  2007cited by this paper
• Subcellular localization of Daxx determines its opposing functions in ischemic cell death

  2007cited by this paper
• Daxx cooperates with the Axin/HIPK2/p53 complex to induce cell death.

  2007influential reference
• Anti-apoptotic Effects of Probucol are Associated with Downregulation of Daxx Expression in THP-1 Macrophage

  2007cited by this paper
• Role of SUMO-interacting motif in Daxx SUMO modification, subnuclear localization, and repression of sumoylated transcription factors.

  2006influential reference
• Critical role for Daxx in regulating Mdm2

  2006cited by this paper
• Dimerization-induced corepressor binding and relaxed DNA-binding specificity are critical for PML/RARA-induced immortalization.

  2006cited by this paper
• Physiological and Functional Interactions between Tcf4 and Daxx in Colon Cancer Cells*

  2006cited by this paper
• Physical and functional interactions between Daxx and STAT3

  2006cited by this paper
• Daxx: death or survival protein?

  2006cited by this paper
• Daxx represses expression of a subset of antiapoptotic genes regulated by nuclear factor-kappaB.

  2006cited by this paper
• SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx.

  2005influential reference
• Daxx Mediates the Small Ubiquitin-like Modifier-dependent Transcriptional Repression of Smad4*

  2005cited by this paper
• Daxx is required for stress-induced cell death and JNK activation

  2005cited by this paper
• Leukaemia: Fusion cooking

  2005cited by this paper
• 1 INVOLVEMENT OF GLUTAREDOXIN-1 AND THIOREDOXIN-1 IN BETA AMYLOID TOXICITY AND ALZHEIMER ’ S DISEASE

  2005cited by this paper
• Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death.

  2005cited by this paper
• SUMO modified proteins localize to the XY body of pachytene spermatocytes

  2004cited by this paper
• DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity

  2004cited by this paper
• Gene Expression Profiling in Fetal, Aged, and Alzheimer Hippocampus: A Continuum of Stress-Related Signaling

  2004cited by this paper
• A Novel Transcription Regulatory Complex Containing Death Domain-associated Protein and the ATR-X Syndrome Protein*

  2004cited by this paper
• Physical and Functional Interactions between Daxx and DNA Methyltransferase 1-Associated Protein, DMAP11

  2004cited by this paper
• Cloning and functional characterization of a rat Daxx that functions as a corepressor for the androgen receptor

  2004cited by this paper
• Tryptophan 621 and Serine 667 Residues of Daxx Regulate Its Nuclear Export during Glucose Deprivation*

  2004cited by this paper
• Heterochromatin and ND10 are cell-cycle regulated and phosphorylation-dependent alternate nuclear sites of the transcription repressor Daxx and SWI/SNF protein ATRX

  2004cited by this paper
• Cloning and functional characterization of a rat Daxx that functions as a corepressor for the androgen receptor

  2004cited by this paper
• Negative Regulation of p53 Functions by Daxx and the Involvement of MDM2*

  2004cited by this paper
• The Transcriptional Repressor hDaxx Potentiates p53-dependent Apoptosis*

  2004cited by this paper
• Physical and functional interactions between Daxx and TSG101.

  2004cited by this paper
• Negative Modulation of Androgen Receptor Transcriptional Activity by Daxx

  2004cited by this paper
• Promyelocytic Leukemia Protein (PML) Functions as a Glucocorticoid Receptor Co-activator by Sequestering Daxx to the PML Oncogenic Domains (PODs) to Enhance Its Transactivation Potential*

  2003cited by this paper
• Heat shock and Cd2+ exposure regulate PML and Daxx release from ND10 by independent mechanisms that modify the induction of heat-shock proteins 70 and 25 differently

  2003cited by this paper
• Role of the ASK1-SEK1-JNK1-HIPK1 Signal in Daxx Trafficking and ASK1 Oligomerization*

  2003cited by this paper
• Inhibition of Stress-Inducible Kinase Pathways by Tumorigenic Mutant p53

  2003cited by this paper
• Human Hepatoma Cells-Terminal Kinase Activation and Apoptosis in 2 c-Jun NH-Induced β HIPK 2 Regulates Transforming Growth Factor-Updated

  2003cited by this paper
• The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

  2003cited by this paper
• ZIP Kinase Triggers Apoptosis from Nuclear PML Oncogenic Domains

  2003cited by this paper
• Epigenetic targets in hematopoietic malignancies

  2003cited by this paper
• Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways

  2003cited by this paper
• Homeodomain-Interacting Protein Kinase 1 Modulates Daxx Localization, Phosphorylation, and Transcriptional Activity

  2003influential reference
• Catalase, but not MnSOD, inhibits glucose deprivation‐activated ASK1‐MEK‐MAPK signal transduction pathway and prevents relocalization of Daxx: Hydrogen peroxide as a major second messenger of metabolic oxidative stress

  2003cited by this paper
• Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML.

  2003cited by this paper
• A cell cycle-regulated GATA factor promotes centromeric localization of CENP-A in fission yeast.

  2003cited by this paper
• Essential Role of the 58-kDa Microspherule Protein in the Modulation of Daxx-dependent Transcriptional Repression as Revealed by Nucleolar Sequestration*

  2002cited by this paper
• Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek.

  2002influential reference
• The Interaction of Pax5 (BSAP) with Daxx Can Result in Transcriptional Activation in B Cells*

  2002influential reference
• The Insulin-sensitive Glucose Transporter, GLUT4, Interacts Physically with Daxx

  2002cited by this paper
• Regulation of Pax3 transcriptional activity by SUMO-1-modified PML

  2001cited by this paper
• Pathways of retinoic acid- or arsenic trioxide-induced PML/RARα catabolism, role of oncogene degradation in disease remission

  2001cited by this paper
• Apoptosis Signal-regulating Kinase 1 Controls the Proapoptotic Function of Death-associated Protein (Daxx) in the Cytoplasm*

  2001cited by this paper
• Identification of differentially expressed genes by serial analysis of gene expression in human prostate cancer.

  2001cited by this paper
• The Interaction of HSP27 with Daxx Identifies a Potential Regulatory Role of HSP27 in Fas‐Induced Apoptosis

  2000cited by this paper
• Inhibition of Daxx-Mediated Apoptosis by Heat Shock Protein 27

  2000cited by this paper
• Promyelocytic Leukemia Protein (Pml) and Daxx Participate in a Novel Nuclear Pathway for Apoptosis

  2000cited by this paper
• EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes

  2000cited by this paper
• The transcriptional role of PML and the nuclear body

  2000cited by this paper
• Sequestration and Inhibition of Daxx-Mediated Transcriptional Repression by PML

  2000influential reference
• Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development.

  1999cited by this paper
• The Pax3–FKHR oncoprotein is unresponsive to the Pax3‐associated repressor hDaxx

  1999influential reference
• Human Daxx regulates Fas‐induced apoptosis from nuclear PML oncogenic domains (PODs)

  1999cited by this paper
• Pml Is Critical for Nd10 Formation and Recruits the Pml-Interacting Protein Daxx to This Nuclear Structure When Modified by Sumo-1

  1999cited by this paper
• A dynamic connection between centromeres and ND10 proteins.

  1999cited by this paper
• Role of PML in cell growth and the retinoic acid pathway.

  1998cited by this paper
• Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death.

  1998influential reference
• Daxx, a novel Fas-binding protein that activates JNK and apoptosis.

  1997influential reference
• Cloning and Expression of Primate Daxx cDNAs and Mapping of the Human Gene to Chromosome 6p21.3 in the MHC Region

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• A Crowdsourced nucleus: understanding nuclear organization in terms of dynamically networked protein function.

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