Daxx represses expression of a subset of antiapoptotic genes regulated by nuclear factor-kappaB.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Cancer Research

• Publication date

  2006-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/0008-5472.CAN-06-1047PMID 16982744
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Active Repression of Antiapoptotic Gene Expression by RelA(p65) NF-κB

  2004cited by this paper
• PML nuclear bodies and apoptosis

  2004cited by this paper
• Physical and Functional Interactions between Daxx and DNA Methyltransferase 1-Associated Protein, DMAP11

  2004cited by this paper
• Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

  2004cited by this paper
• Promyelocytic Leukemia Protein (PML) Functions as a Glucocorticoid Receptor Co-activator by Sequestering Daxx to the PML Oncogenic Domains (PODs) to Enhance Its Transactivation Potential*

  2003cited by this paper
• The role of Rel/NF-κB transcription factors in B lymphocyte survival

  2003cited by this paper
• Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways

  2003cited by this paper
• Genetic analysis of NF‐κB/Rel transcription factors defines functional specificities

  2003cited by this paper
• RNAi reveals anti-apoptotic and transcriptionally repressive activities of DAXX

  2003cited by this paper
• IκB-ζ, a new anti-inflammatory nuclear protein induced by lipopolysaccharide, is a negative regulator for nuclear factor-κB

  2003cited by this paper
• The role of Rel/NF-kappaB transcription factors in B lymphocyte survival.

  2003cited by this paper
• Daxx enhances Fas‐mediated apoptosis in a murine pro‐B cell line, BAF3

  2003cited by this paper
• The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

  2003cited by this paper
• IkappaB-zeta, a new anti-inflammatory nuclear protein induced by lipopolysaccharide, is a negative regulator for nuclear factor-kappaB.

  2003cited by this paper
• ZIP Kinase Triggers Apoptosis from Nuclear PML Oncogenic Domains

  2003cited by this paper
• Determination of Minimum Herpes Simplex Virus Type 1 Components Necessary To Localize Transcriptionally Active DNA to ND10

  2003cited by this paper
• Homeodomain-Interacting Protein Kinase 1 Modulates Daxx Localization, Phosphorylation, and Transcriptional Activity

  2003cited by this paper
• Differences in DNA binding properties between E2F1 and E2F4 specify repression of the Mcl-1 promoter

  2002cited by this paper
• The Insulin-sensitive Glucose Transporter, GLUT4, Interacts Physically with Daxx

  2002cited by this paper
• RelB-p50 NF-kappa B complexes are selectively induced by cytomegalovirus immediate-early protein 1: differential regulation of Bcl-x(L) promoter activity by NF-kappa B family members.

  2002cited by this paper
• Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek.

  2002cited by this paper
• RelB-p50 NF-κB Complexes Are Selectively Induced by Cytomegalovirus Immediate-Early Protein 1: Differential Regulation of Bcl-xL Promoter Activity by NF-κB Family Members

  2002cited by this paper
• The Interaction of Pax5 (BSAP) with Daxx Can Result in Transcriptional Activation in B Cells*

  2002cited by this paper
• Direct repression of the Mcl-1 promoter by E2F1

  2002cited by this paper
• Missing pieces in the NF-kappaB puzzle.

  2002cited by this paper
• TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

  2001cited by this paper
• NF-κB Signals Induce the Expression of c-FLIP

  2001cited by this paper
• MAIL, a novel nuclear IκB protein that potentiates LPS‐induced IL‐6 production

  2000cited by this paper
• Involvement of Two NF-κB Binding Elements in Tumor Necrosis Factor α-, CD40-, and Epstein-Barr Virus Latent Membrane Protein 1-mediated Induction of the Cellular Inhibitor of Apoptosis Protein 2 Gene*

  2000cited by this paper
• The Daxx enigma

  2000cited by this paper
• Promyelocytic Leukemia Protein (Pml) and Daxx Participate in a Novel Nuclear Pathway for Apoptosis

  2000cited by this paper
• The NF-κB Cascade Is Important in Bcl-xL Expression and for the Anti-Apoptotic Effects of the CD28 Receptor in Primary Human CD4+ Lymphocytes1

  2000cited by this paper
• EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes

  2000cited by this paper
• Review: properties and assembly mechanisms of ND10, PML bodies, or PODs.

  2000cited by this paper
• MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production.

  2000cited by this paper
• Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development.

  1999cited by this paper
• Apoptosis: Silencing the death receptors

  1999cited by this paper
• Human Daxx regulates Fas‐induced apoptosis from nuclear PML oncogenic domains (PODs)

  1999cited by this paper
• Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx.

  1998cited by this paper
• Diva, a Bcl-2 Homologue that Binds Directly to Apaf-1 and Induces BH3-independent Cell Death*

  1998cited by this paper
• Daxx, a novel Fas-binding protein that activates JNK and apoptosis.

  1997cited by this paper
• Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members.

  1997cited by this paper
• Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family.

  1995cited by this paper
• Immunohistochemical analysis of in vivo patterns of Bcl-X expression.

  1994cited by this paper

• DAXX in Metabolic, Aging, and Immune Regulation: Recent Insights

  2026cites this paper
• ATRX/DAXX: Guarding the Genome against the Hazards of ALT

  2023cites this paper
• The Physiological and Pathophysiological Role of IL-6/STAT3-Mediated Signal Transduction and STAT3 Binding Partners in Therapeutic Applications.

  2023cites this paper
• A Tale of Usurpation and Subversion: SUMO-Dependent Integrity of Promyelocytic Leukemia Nuclear Bodies at the Crossroad of Infection and Immunity

  2021cites this paper
• PML-Dependent Memory of Type I Interferon Treatment Results in a Restricted Form of HSV Latency

  2021cites this paper
• PML‐NB‐dependent type I interferon memory results in a restricted form of HSV latency

  2021cites this paper
• Expanding the Known Functional Repertoire of the Human Cytomegalovirus pp71 Protein

  2020cites this paper
• DAXX in cancer: phenomena, processes, mechanisms and regulation

  2019cites this paper
• Biological characteristics of transcription factor RelB in different immune cell types: implications for the treatment of multiple sclerosis

  2019cites this paper
• Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells

  2019cites this paper
• Noncanonical NF-κB in Cancer

  2018cites this paper
• Dissecting the role of PML-II in gene transcription and in IFN alpha-mediated apoptosis

  2018cites this paper
• Manipulation of Non-canonical NF-κB Signaling by Non-oncogenic Viruses

  2018cites this paper
• Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis

  2016cites this paper
• Role of the nucleus in apoptosis: signaling and execution

  2015cites this paper
• Multifunctional adaptor protein Daxx interacts with chromatin-remodelling ATPase Brg1

  2015cites this paper
• Daxx from Pacific white shrimp Litopenaeus vannamei is involved in activation of NF-κB pathway.

  2015cites this paper
• The DAXX co-repressor is directly recruited to active regulatory elements genome-wide to regulate autophagy programs in a model of human prostate cancer

  2015cites this paper
• Signal transducer and activator of transcription 3 regulation by novel binding partners.

  2015cites this paper
• Arsenic trioxide and interferon alpha circumvent tyrosine kinase inhibitors resistance in chronic myeloid leukemia models

  2015cites this paper
• Dengue virus disrupts Daxx and NF-κB interaction to induce CD137-mediated apoptosis.

  2014cites this paper
• PML-mediated signaling and its role in cancer stem cells

  2014cites this paper
• SUMOylation Attenuates the Transcriptional Activity of the NF‐κB Subunit RelB

  2014cites this paper
• Berberine represses DAXX gene transcription and induces cancer cell apoptosis

  2013cites this paper
• Daxx Upregulation within the Cytoplasm of Reovirus-Infected Cells Is Mediated by Interferon and Contributes to Apoptosis

  2013cites this paper
• Methylation of RASSF1A gene promoter is regulated by p53 and DAXX

  2013cites this paper
• SUMO and Parkinson’s Disease

  2013cites this paper
• Phosphorylation Drives an Apoptotic Protein to Activate Antiapoptotic Genes

  2013influential citation
• SUMOylation in cell death: SUMO E3 ligase PIAS1 plays a critical role in determining cell survival following UV stress

  2012cites this paper
• The role of PML ubiquitination in human malignancies

  2012cites this paper
• Single-cell analysis of Daxx and ATRX-dependent transcriptional repression

  2012cites this paper
• The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci

  2012influential citation
• XWH-081-0209 TITLE : A Mechanistic Study of Proapoptotic Daxx-Par 4 Axis in Prostate Cancer

  2011cites this paper
• NEW INSIGHTS ON PML TUMOR SUPPRESSOR DEGRADATION IN CANCER

  2011cites this paper
• Structural and functional roles of Daxx SIM phosphorylation in SUMO paralog-selective binding and apoptosis modulation.

  2011cites this paper
• DAXX (death-associated protein 6)

  2011cites this paper
• Chemical Agonists of the PML/Daxx Pathway for Prostate Cancer Therapy

  2011cites this paper
• A High-Content Screening (HCS) Assay for the Identification of Chemical Inducers of PML Oncogenic Domains (PODs)

  2011cites this paper
• Molekulare Grundlagen der Spezies-Spezifität bei Zytomegalieviren

  2010cites this paper
• Classical NF-κB Activation Negatively Regulates Noncanonical NF-κB-dependent CXCL12 Expression*

  2010cites this paper
• Signalling to drug resistance in CLL.

  2010cites this paper
• Genome-Wide Localization And Novel Deposition Pathways Of Histone Variant H3.3 In Embryonic Stem And Neuronal Precursor Cells

  2010influential citation
• Functional involvement of Daxx in gp130‐mediated cell growth and survival in BaF3 cells

  2010cites this paper
• PML nuclear bodies as sites of epigenetic regulation.

  2009cites this paper
• Identification of two independent SUMO-interacting motifs in Daxx: Evolutionary conservation from Drosophila to humans and their biochemical functions

  2009cites this paper
• Sirt1 contributes critically to the redox-dependent fate of neural progenitors

  2008cites this paper
• Identification of lysine residues critical for the transcriptional activity and polyubiquitination of the NF-kappaB family member RelB.

  2008cites this paper
• FAD24, a regulator of adipogenesis and DNA replication, inhibits H-RAS-mediated transformation by repressing NF-kappaB activity.

  2008cites this paper
• Daxx : from nuclear structure to protein function

  2008cites this paper
• In vitro selection of optimal RelB/p52 DNA-binding motifs.

  2008cites this paper
• Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation.

  2008cites this paper
• Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus

  2008cites this paper
• PML NBs (ND10) and Daxx: from nuclear structure to protein function.

  2008cites this paper
• Regulation of apoptosis by PML and the PML-NBs

  2008cites this paper
• Daxx and Rassf1 define a novel mitotic stress checkpoint that is critical for cellular Taxol response

  2008cites this paper
• Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

  2007cites this paper
• Inhibition of NF-kappaB acetylation and its transcriptional activity by Daxx.

  2007cites this paper
• Inhibition of NF-κB Acetylation and its Transcriptional Activity by Daxx

  2007cites this paper
• Daxx mediates SUMO-dependent transcriptional control and subnuclear compartmentalization.

  2007cites this paper