Comprehensive relationships between gut microbiome and faecal metabolome in individuals with type 2 diabetes and its complications

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Endocrine

• Publication date

  2019-10-07

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s12020-019-02103-8PMID 31591683
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease.

  2018cited by this paper
• Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1.

  2018cited by this paper
• Aberrant intestinal microbiota in individuals with prediabetes

  2018cited by this paper
• Implication of gut microbiota metabolites in cardiovascular and metabolic diseases

  2018cited by this paper
• Antidepressant-Like Effects of Cistanche tubulosa Extract on Chronic Unpredictable Stress Rats Through Restoration of Gut Microbiota Homeostasis

  2018cited by this paper
• Gut microbiota dysbiosis contributes to the development of hypertension

  2017cited by this paper
• Alterations of Urinary Microbiota in Type 2 Diabetes Mellitus with Hypertension and/or Hyperlipidemia

  2017cited by this paper
• HMDB 4.0: the human metabolome database for 2018

  2017cited by this paper
• Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese mice

  2017cited by this paper
• Role of Gut Microbiota on Cardio-Metabolic Parameters and Immunity in Coronary Artery Disease Patients with and without Type-2 Diabetes Mellitus

  2017cited by this paper
• Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

  2017cited by this paper
• Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

  2017cited by this paper
• A Non-Targeted Liquid Chromatographic-Mass Spectrometric Metabolomics Approach for Association with Coronary Artery Disease: An Identification of Biomarkers for Depiction of Underlying Biological Mechanisms

  2017cited by this paper
• Increased Trimethylamine N-Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus.

  2017cited by this paper
• Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug

  2017cited by this paper
• A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

  2017cited by this paper
• Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease.

  2017cited by this paper
• The gut microbiome in atherosclerotic cardiovascular disease

  2017cited by this paper
• Interplay between gut microbiota, its metabolites and human metabolism: Dissecting cause from consequence

  2016cited by this paper
• Human gut microbes impact host serum metabolome and insulin sensitivity

  2016cited by this paper
• Disentangling the effects of type 2 diabetes and metformin on the human gut microbiota

  2016cited by this paper
• Looking for a Signal in the Noise: Revisiting Obesity and the Microbiome

  2016cited by this paper
• The Human Gut Microbiota.

  2016cited by this paper
• Insulin resistance is associated with specific gut microbiota in appendix samples from morbidly obese patients.

  2016cited by this paper
• Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism.

  2016cited by this paper
• The Human Intestinal Microbiome in Health and Disease.

  2016cited by this paper
• Protective effect of polysaccharides fractions from Sijunzi decoction in reserpine-induced spleen deficiency rats

  2016cited by this paper
• Farnesoid X Receptor Inhibits Glucagon-Like Peptide-1 Production by Enteroendocrine L-cells

  2015cited by this paper
• Disentangling the effects of type 2 diabetes and metformin on the human gut microbiota

  2015cited by this paper
• Serum metabolite signatures of type 2 diabetes mellitus complications.

  2015cited by this paper
• Short-chain fatty acids in control of body weight and insulin sensitivity

  2015cited by this paper
• Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

  2015cited by this paper
• STAMP: statistical analysis of taxonomic and functional profiles

  2014cited by this paper
• Adiposity, gut microbiota and faecal short chain fatty acids are linked in adult humans

  2014cited by this paper
• Insights Into the Role of the Microbiome in Obesity and Type 2 Diabetes

  2014cited by this paper
• Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

  2014cited by this paper
• The gut microbiota of Colombians differs from that of Americans, Europeans and Asians

  2014cited by this paper
• Genomics: A gut prediction

  2013cited by this paper
• Standards of Medical Care in Diabetes—2014

  2013cited by this paper
• Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.

  2013cited by this paper
• Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

  2013cited by this paper
• Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

  2013cited by this paper
• Gut metagenome in European women with normal, impaired and diabetic glucose control

  2013cited by this paper
• A metagenome-wide association study of gut microbiota in type 2 diabetes

  2012cited by this paper
• Fecal metabolome profiling of liver cirrhosis and hepatocellular carcinoma patients by ultra performance liquid chromatography-mass spectrometry.

  2011cited by this paper
• Standards of Medical Care in Diabetes—2011

  2011cited by this paper
• An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

  2011cited by this paper
• Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

  2011cited by this paper
• QIIME allows analysis of high-throughput community sequencing data

  2010cited by this paper
• Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss

  2010cited by this paper
• TGR5-mediated bile acid sensing controls glucose homeostasis.

  2009cited by this paper
• Structuring and extracting knowledge for the support of hypothesis generation in molecular biology

  2009influential reference
• Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model

  2008cited by this paper
• Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R

  2008cited by this paper
• WGCNA: an R package for weighted correlation network analysis

  2008cited by this paper
• LMSD: LIPID MAPS structure database

  2006cited by this paper
• UniFrac: a New Phylogenetic Method for Comparing Microbial Communities

  2005cited by this paper
• METLIN: A Metabolite Mass Spectral Database

  2005cited by this paper
• Fecal acetate is inversely related to acetate absorption from the human rectum and distal colon.

  2003cited by this paper

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