The Role of Particle Geometry and Mechanics in the Biological Domain

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Advanced Healthcare Materials

• Publication date

  2012-01-11

• Fields of study

  Biology, Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1002/adhm.201100012PMID 23184686
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution.

  2012cited by this paper
• Synthesis and assembly of anisotropic nanoparticles

  2011cited by this paper
• Release Properties of Pressurized Microgel Templated Capsules

  2011cited by this paper
• Engineered hydrogen-bonded polymer multilayers: from assembly to biomedical applications.

  2011cited by this paper
• Extravasation of polymeric nanomedicines across tumor vasculature.

  2011cited by this paper
• Toward therapeutic delivery with layer-by-layer engineered particles.

  2011cited by this paper
• Redox-active polymer microcapsules for the delivery of a survivin-specific siRNA in prostate cancer cells.

  2011cited by this paper
• Cellular uptake of elastic nanoparticles.

  2011cited by this paper
• Comparison between measurements of elasticity and free amino group content of ovalbumin microcapsule membranes: discrimination of the cross-linking degree.

  2011cited by this paper
• Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

  2011cited by this paper
• Gold Nanoparticle Synthesis, Morphology Control, and Stabilization Facilitated by Functional Polymers

  2011cited by this paper
• Preclinical and clinical studies of NK012, an SN-38-incorporating polymeric micelles, which is designed based on EPR effect.

  2011cited by this paper
• Multifunctional mesoporous silica nanocomposite nanoparticles for theranostic applications.

  2011cited by this paper
• Size and shape effects in the biodistribution of intravascularly injected particles.

  2010cited by this paper
• Computer simulation of the translocation of nanoparticles with different shapes across a lipid bilayer.

  2010cited by this paper
• Strategies in the design of nanoparticles for therapeutic applications

  2010cited by this paper
• Rheology of Soft Materials

  2010cited by this paper
• Supporting information for Synthesis and Directed Self-Assembly of Patterned Anisometric Polymeric Particles

  2010cited by this paper
• Layer-by-layer-assembled capsules and films for therapeutic delivery.

  2010cited by this paper
• The rheology of suspensions of solid particles

  2010cited by this paper
• Mechanobiology: correlation between mechanical stability of microcapsules studied by AFM and impact of cell-induced stresses.

  2010cited by this paper
• Macrophages Recognize Size and Shape of Their Targets

  2010cited by this paper
• Triggering release of encapsulated cargo.

  2010cited by this paper
• Particle shape: a new design parameter for passive targeting in splenotropic drug delivery.

  2010cited by this paper
• Highly ordered hexagonal arrays of hybridized micelles from bimodal self-assemblies of diblock copolymer micelles.

  2010cited by this paper
• Endocytosis and Intracellular Distribution of PLGA Particles in Endothelial Cells: Effect of Particle Geometry.

  2010cited by this paper
• Targeting of cancer cells using click-functionalized polymer capsules.

  2010cited by this paper
• Characterization of adhesion phenomena and contact of surfaces by soft colloidal probe AFM

  2010cited by this paper
• Quantification of release from microcapsules upon mechanical deformation with AFM

  2010cited by this paper
• Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods.

  2010cited by this paper
• Uptake and intracellular fate of disulfide-bonded polymer hydrogel capsules for Doxorubicin delivery to colorectal cancer cells.

  2010cited by this paper
• Fabrication of asymmetric "Janus" particles via plasma polymerization.

  2010cited by this paper
• Probing elasticity at the nanoscale: Terahertz acoustic vibration of small metal nanoparticles.

  2010cited by this paper
• Synthesis and catalytic properties of metal nanoparticles: Size, shape, support, composition, and oxidation state effects

  2010cited by this paper
• Fabrication of stable anisotropic microcapsules

  2009cited by this paper
• Computationally guided photothermal tumor therapy using long-circulating gold nanorod antennas.

  2009cited by this paper
• Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigens.

  2009cited by this paper
• Shape‐Controlled Synthesis of Pd Nanocrystals in Aqueous Solutions

  2009cited by this paper
• pH-responsive reversibly swellable nanotube arrays.

  2009cited by this paper
• Effect of mechanical properties of hydrogel nanoparticles on macrophage cell uptake

  2009cited by this paper
• Red blood cell-mimicking synthetic biomaterial particles

  2009cited by this paper
• Poly(Lactic-co-Glycolic) Acid as a Carrier for Imaging Contrast Agents

  2009cited by this paper
• Tuning the formation and degradation of layer-by-layer assembled polymer hydrogel microcapsules.

  2009cited by this paper
• Designer Biomaterials for Nanomedicine

  2009cited by this paper
• The microcontainer shape in electropolymerization on bubbles

  2009cited by this paper
• Squishy non-spherical hydrogel microparticles.

  2009cited by this paper
• On the mechanical stability of polymeric microcontainers functionalized with nanoparticles

  2009cited by this paper
• A Continuous Flow Synthesis of Micrometer‐Sized Actuators from Liquid Crystalline Elastomers

  2009cited by this paper
• A review of stimuli-responsive nanocarriers for drug and gene delivery.

  2008cited by this paper
• Polymersomes: a new multi-functional tool for cancer diagnosis and therapy.

  2008cited by this paper
• The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows.

  2008cited by this paper
• The effect of particle design on cellular internalization pathways

  2008cited by this paper
• Loading PEG-Catalase into Filamentous and Spherical Polymer Nanocarriers

  2008cited by this paper
• Nanotechnology and cancer.

  2008cited by this paper
• Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles.

  2008cited by this paper
• The receptor-mediated endocytosis of nonspherical particles.

  2008cited by this paper
• Shape Induced Inhibition of Phagocytosis of Polymer Particles

  2008cited by this paper
• Young's moduli of surface-bound liposomes by atomic force microscopy force measurements.

  2008cited by this paper
• Microfabricated Particles for Engineered Drug Therapies: Elucidation into the Mechanisms of Cellular Internalization of PRINT Particles

  2008cited by this paper
• Intravascular Delivery of Particulate Systems: Does Geometry Really Matter?

  2008cited by this paper
• Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers.

  2008cited by this paper
• Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications

  2007cited by this paper
• Soft biological materials and their impact on cell function.

  2007cited by this paper
• Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers.

  2007cited by this paper
• Shape effects of filaments versus spherical particles in flow and drug delivery.

  2007cited by this paper
• Polymeric nanovehicles for anticancer drugs with triggering release mechanisms

  2007cited by this paper
• Renal clearance of quantum dots

  2007cited by this paper
• Synthesis and self-assembly of amphiphilic polymeric microparticles.

  2007cited by this paper
• Hollow polyelectrolyte multilayer tubes: mechanical properties and shape changes.

  2007cited by this paper
• Activity of immobilized trypsin in the layer structure of polyelectrolyte microcapsules (PEMC).

  2007cited by this paper
• Nanomechanical analysis of cells from cancer patients.

  2007cited by this paper
• Nanomedicine: elastic clues in cancer detection.

  2007cited by this paper
• Making polymeric micro- and nanoparticles of complex shapes

  2007cited by this paper
• Mechanical properties of micro-and nanocapsules : Single-capsule measurements

  2007cited by this paper
• Layer-by-layer engineered capsules and their applications

  2006cited by this paper
• Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers.

  2006cited by this paper
• Extended DLVO interactions between spherical particles and rough surfaces.

  2006cited by this paper
• Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles.

  2006cited by this paper
• The inflammatory role of platelets in cystic fibrosis.

  2006cited by this paper
• Complete shape retention in the transformation of silica to polymer micro-objects

  2006cited by this paper
• Stiffness of normal and pathological erythrocytes studied by means of atomic force microscopy.

  2006cited by this paper
• Carbon nanotubes as nanomedicines: from toxicology to pharmacology.

  2006cited by this paper
• Role of target geometry in phagocytosis.

  2006cited by this paper
• Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells.

  2006cited by this paper
• Continuous-flow lithography for high-throughput microparticle synthesis

  2006cited by this paper
• Intracellularly Degradable Polyelectrolyte Microcapsules

  2006cited by this paper
• Polyelectrolyte Functionalization of Electrospun Fibers

  2006cited by this paper
• pH-Triggered softening of crosslinked hydrogen-bonded capsules.

  2006cited by this paper
• Red blood cell templated polyelectrolyte capsules: A novel vehicle for the stable encapsulation of DNA and proteins

  2006cited by this paper
• MECHANICAL BEHAVIOR AND CHARACTERIZATION OF MICROCAPSULES

  2006cited by this paper
• Non-viral gene delivery regulated by stiffness of cell adhesion substrates

  2005cited by this paper
• Highly efficient molecular delivery into mammalian cells using carbon nanotube spearing

  2005cited by this paper
• Carbon nanotubes as intracellular protein transporters: generality and biological functionality.

  2005cited by this paper
• Nanostructure-mediated drug delivery.

  2005cited by this paper
• Gold nanorods: Synthesis, characterization and applications

  2005cited by this paper
• Polyelectrolyte-Coated Gold Nanorods: Synthesis, Characterization and Immobilization

  2005cited by this paper
• Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model.

  2005cited by this paper
• Mechanics of receptor-mediated endocytosis.

  2005cited by this paper
• Controlled synthesis of nonspherical microparticles using microfluidics.

  2005cited by this paper
• Micromachined devices: the impact of controlled geometry from cell-targeting to bioavailability.

  2005cited by this paper

• A catalase-powered self-oxygen-generating soft nanomotor for photodynamic therapy of osteosarcoma

  2025cites this paper
• Progress in the mechanical properties of nanoparticles for tumor-targeting delivery.

  2025cites this paper
• GDGen: A gradient descent-based methodology for the generation of optimized spatial configurations of customized clusters in computational simulations

  2025cites this paper
• From Single Ligand–Receptor Bond Strength to Collective Avidity: Mechanics-Guided Superselective Nanoparticle Adhesion to Biological Membranes

  2025cites this paper
• A Review on Investigating the Interactions between Nanoparticles and the Pulmonary Surfactant Monolayer with Coarse-Grained Molecular Dynamics Method.

  2024cites this paper
• Regulation of Cell–Nanoparticle Interactions through Mechanobiology

  2024cites this paper
• Polymeric Nanoparticles for Drug Delivery

  2024cites this paper
• Recent Advances in Targeted Drug Delivery Strategy for Enhancing Oncotherapy

  2023cites this paper
• YAP Signaling Regulates the Cellular Uptake and Therapeutic Effect of Nanoparticles

  2023cites this paper
• Co‐Polymer Carrier with Dual Advantages of Cartilage‐Penetrating and Targeting Improves Delivery and Efficacy of MicroRNA Treatment of Osteoarthritis

  2022cites this paper
• Polymeric Nanoparticles for Inhaled Vaccines

  2022cites this paper
• Effect of the stiffness of one-layer protein-based microcapsules on dendritic cell uptake and endocytic mechanism.

  2021cites this paper
• Polymeric Particulates of Controlled Rigidity for Biomedical Applications

  2021cites this paper
• Biomimetic micro/nano structures for biomedical applications

  2020cites this paper
• Physiologically Relevant Mechanics of Biodegradable Polyester Nanoparticles.

  2020cites this paper
• Effect of elasticity on the phagocytosis of micro/nanoparticles.

  2020cites this paper
• Mechanism of Coupling Nanoparticle Stiffness with Shape for Endocytosis: From Rodlike Penetration to Wormlike Wriggling.

  2020cites this paper
• Integration of hyper-compliant microparticles into a 3D melanoma tumor model.

  2019cites this paper
• Thermodynamic analysis of multivalent binding of functionalized nanoparticles to membrane surface reveals the importance of membrane entropy and nanoparticle entropy in adhesion of flexible nanoparticles.

  2019cites this paper
• The Hemocompatibility of Nanoparticles: A Review of Cell–Nanoparticle Interactions and Hemostasis

  2019cites this paper
• Rigidity-Dependent Placental Cells Uptake of Silk-Based Microcapsules.

  2019cites this paper
• Chain-Length- and Saturation-Tuned Mechanics of Fluid Nanovesicles Direct Tumor Delivery.

  2019cites this paper
• Fabrication and flow characteristics of monodisperse bullet-shaped microparticles with controllable structures

  2019cites this paper
• Shape-Dependent Biodistribution of Biocompatible Silk Microcapsules.

  2019cites this paper
• The role of nanoparticle shape in translocation across the pulmonary surfactant layer revealed by molecular dynamics simulations

  2018cites this paper
• Construction of biconcave hemoglobin-based microcapsules and electrochemical evaluation for its ability of oxygen carry

  2018cites this paper
• Understanding the Effects of Nanocapsular Mechanical Property on Passive and Active Tumor Targeting.

  2018cites this paper
• In Vivo Study of Spiky Fe3O4@Au Nanoparticles with Different Branch Lengths: Biodistribution, Clearance, and Biocompatibility in Mice.

  2018cites this paper
• Manipulation and Imaging of Interactions Between Layer-by-layer Capsules and Live Cells Using Nanopipettes and SICM

  2018cites this paper
• Cellular internalization of polypeptide-based nanoparticles: effects of size, shape and surface morphology.

  2018cites this paper
• Facile production of nanocomposites of carbon nanotubes and polycaprolactone with high aspect ratios with potential applications in drug delivery

  2018cites this paper
• Recent and prominent examples of nano- and microarchitectures as hemoglobin-based oxygen carriers.

  2018cites this paper
• Chapter 2 Improved Targeting of Cancers with Nanotherapeutics

  2018cites this paper
• Shear rate dependent margination of sphere-like, oblate-like and prolate-like micro-particles within blood flow.

  2018cites this paper
• DESIGN AND ANALYSIS OF CURCUMIN CONJUGATED POLY(BETA-AMINO ESTER) NETWORKS FOR CONTROLLED RELEASE IN OXIDATIVE STRESS ENVIRONMENTS

  2018cites this paper
• Study on the formation and properties of red blood cell-like Fe3O4/TbLa3(Bim)12/PLGA composite particles

  2018cites this paper
• Improved Targeting of Cancers with Nanotherapeutics.

  2017cites this paper
• Effect of internal architecture on microgel deformation in microfluidic constrictions.

  2017cites this paper
• Impact of particle elasticity on particle‐based drug delivery systems☆

  2017cites this paper
• Nanoparticles and innate immunity: new perspectives on host defence.

  2017cites this paper
• In vivo high-efficiency targeted photodynamic therapy of ultra-small Fe3O4@polymer-NPO/PEG-Glc@Ce6 nanoprobes based on small size effect

  2017cites this paper
• Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery.

  2017cites this paper
• In-vitro anti-cancer activity of shape controlled silver nanoparticles (AgNPs) in various organ specific cell lines

  2017cites this paper
• Layer‐by‐Layer Technique: From Capsule Assembly to Application in Biological Domains

  2017cites this paper
• CALCIUM CARBONATE-BASED PARTICLES AND CAPSULES FOR THERAPEUTIC ENZYMES

  2017cites this paper
• Template-Assisted Approaches for Preparation of Nano-sized Polymer Structures

  2016cites this paper
• Biomimetic Concealing of PLGA Microspheres in a 3D Scaffold to Prevent Macrophage Uptake.

  2016cites this paper
• Towards the Fabrication of Polyelectrolyte-Based Nanocapsules for Bio-Medical Applications

  2016cites this paper
• Interactions between inhaled nanomaterials and biomolecules in the lung -a study of the risks of systemic effects, Report 14/16

  2016cites this paper
• Shape-Adaptable Polymeric Particles for Controlled Delivery

  2016cites this paper
• Role of particle size, shape, and stiffness in design of intravascular drug delivery systems: insights from computations, experiments, and nature.

  2016cites this paper
• Superparamagnetic anisotropic nano-assemblies with longer blood circulation in vivo: a highly efficient drug delivery carrier for leukemia therapy.

  2016cites this paper
• Role of particle size, shape, and stiffness in design of intravascular drug delivery systems: insights from computations, experiments, and nature.

  2016cites this paper
• Copper-Mediated Living Radical Polymerization (Atom Transfer Radical Polymerization and Copper(0) Mediated Polymerization): From Fundamentals to Bioapplications.

  2016cites this paper
• Passive tumour targeting and extravasation of cylindrical polymer brushes in mouse xenografts.

  2016cites this paper
• Non-special particle generation from 4D optofluidic fabrication

  2016cites this paper
• Towards the Fabrication of Polyelectrolyte-Based Nanocapsules for Bio-Medical Applications

  2016cites this paper
• Stable non-covalent labeling of layered silicate nanoparticles for biological imaging.

  2016cites this paper
• Flexible Octopus-Shaped Hydrogel Particles for Specific Cell Capture.

  2016cites this paper
• The Role of Carrier Geometry in Overcoming Biological Barriers to Drug Delivery.

  2016cites this paper
• Nanometric emulsions encapsulating solid particles as alternative carriers for intracellular delivery.

  2016cites this paper
• Near-Surface Motion and Dynamic Adhesion during Silica Microparticle Capture on a Polymer (Solvated PEG) Brush via Hydrogen Bonding

  2016cites this paper
• Probing cell internalisation mechanics with polymer capsules.

  2016cites this paper
• Synthesis of Nonspherical Microcapsules through Controlled Polyelectrolyte Coating of Hydrogel Templates.

  2015cites this paper
• Modular Vaccine Design Using Carrier-Free Capsules Assembled from Polyionic Immune Signals

  2015cites this paper
• In the Best of Health

  2015cites this paper
• Structure Governs the Deformability of Polymer Particles in a Microfluidic Blood Capillary Model.

  2015cites this paper
• The role of capsule stiffness on cellular processing

  2015cites this paper
• Spontaneous nematic alignment of a lipid nanotube in aqueous solutions.

  2015cites this paper
• NOVEL STRATEGY TO PRODUCE NON-SPHERICAL POLYMERIC MICROPARTICLES FOR DRUG DELIVERY AND TISSUE ENGINEERING RELATORE

  2015cites this paper
• Shape affects the interactions of nanoparticles with pulmonary surfactant

  2015cites this paper
• Analysis of Particle Transport and Deposition of Micron-Sized Particles in a 90° Bend Using a Two-Fluid Eulerian–Eulerian Approach

  2015influential citation
• Inverse Opal Scaffolds with an Embossed Surface Pattern Prepared from Sticky Golf‐Ball‐Shaped Microparticle Assemblies

  2015cites this paper
• A method to tune the shape of protein-encapsulated polymeric microspheres

  2015cites this paper
• Engineering and evaluating drug delivery particles in microfluidic devices.

  2014cites this paper
• pH-responsive hydrogel cubes for release of doxorubicin in cancer cells.

  2014cites this paper
• Emulsion click microspheres: morphology/shape control by surface cross-linking and a porogen

  2014cites this paper
• Stop flow lithography synthesis of non-spherical metal oxide particles

  2014cites this paper
• Emerging methods for the fabrication of polymer capsules.

  2014cites this paper
• Stop flow lithography synthesis and characterization of structured microparticles

  2014cites this paper
• Shape and orientation matter for the cellular uptake of nonspherical particles.

  2014cites this paper
• Shape memory particles capable of controlled geometric and chemical asymmetry made from aliphatic polyesters.

  2014cites this paper
• Enhanced cell adhesion to the dimpled surfaces of golf-ball-shaped microparticles.

  2014cites this paper
• Fabrication of biconcave discoidal silica capsules and their uptake behavior by smooth muscle cells.

  2014cites this paper
• Cryptic epitopes of albumin determine mononuclear phagocyte system clearance of nanomaterials.

  2014cites this paper
• Capillary micromechanics for core-shell particles.

  2014cites this paper
• Synthesis of Protein‐Based, Rod‐Shaped Particles from Spherical Templates using Layer‐by‐Layer Assembly

  2013cites this paper
• Multiscale modeling and uncertainty quantification in nanoparticle-mediated drug/gene delivery

  2013cites this paper
• Multifunctional graphene quantum dots-conjugated titanate nanoflowers for fluorescence-trackable targeted drug delivery

  2013cites this paper
• Mechanics of pH-responsive hydrogel capsules.

  2013cites this paper
• Biocompatible shaped particles from dried multilayer polymer capsules.

  2013cites this paper
• Near‐Incompressible Faceted Polymer Microcapsules from Metal‐Organic Framework Templates

  2013cites this paper
• Microparticulate biomolecules by mild CaCO3 templating.

  2013cites this paper
• Fabrication of Red‐Blood‐Cell‐Like Polyelectrolyte Microcapsules and Their Deformation and Recovery Behavior Through a Microcapillary

  2013cites this paper
• Wrapping of ellipsoidal nano-particles by fluid membranes

  2013cites this paper
• Effect of pH and Temperature on PMPC–PDPA Copolymer Self-Assembly

  2013cites this paper
• Variation of the effect of calcium phosphate enhancement of implanted silk fibroin ligament bone integration.

  2013cites this paper
• Hippocrates, Healing, and Healthcare Materials

  2013cites this paper
• The ‘nanobig rod’ class of gold nanorods: optimized dimensions for improved in vivo therapeutic and imaging efficacy

  2013cites this paper
• Multivalente gerichtete Organisation von kolloidalen Partikeln

  2013cites this paper