SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Nature Biotechnology

• Publication date

  2011-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nbt.2005PMID 22020386PMCID PMC4949030
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Modelling the long QT syndrome with induced pluripotent stem cells

  2011cited by this paper
• An Engineered Cardiac Reporter Cell Line Identifies Human Embryonic Stem Cell-Derived Myocardial Precursors

  2011cited by this paper
• NKX2-5eGFP/w hESCs for isolation of human cardiac progenitors and cardiomyocytes

  2011cited by this paper
• Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells

  2011cited by this paper
• Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines.

  2011cited by this paper
• Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis.

  2011cited by this paper
• Patient-specific induced pluripotent stem cell derived models of LEOPARD syndrome

  2010cited by this paper
• Nongenetic method for purifying stem cell–derived cardiomyocytes

  2010cited by this paper
• Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells

  2009cited by this paper
• CD90 Expression on human primary cells and elimination of contaminating fibroblasts from cell cultures

  2009cited by this paper
• Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway.

  2009cited by this paper
• Prevascularization of cardiac patch on the omentum improves its therapeutic outcome

  2009cited by this paper
• Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue

  2009cited by this paper
• Transplantation of a Tissue-Engineered Human Vascularized Cardiac Muscle

  2009cited by this paper
• Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery.

  2009cited by this paper
• Reprogramming of human somatic cells to pluripotency with defined factors

  2008cited by this paper
• Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

  2008cited by this paper
• Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development.

  2008cited by this paper
• A method for genetic modification of human embryonic stem cells using electroporation

  2007cited by this paper
• Transgenic enrichment of cardiomyocytes from human embryonic stem cells.

  2007cited by this paper
• Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures.

  2007cited by this paper
• Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts

  2007cited by this paper
• Species- and cell type-specific interactions between CD47 and human SIRPalpha.

  2006cited by this paper
• Negative Regulation of Phagocytosis in Macrophages by the CD47-SHPS-1 System1

  2005cited by this paper
• Role of SHPS-1 in the regulation of insulin-like growth factor I-stimulated Shc and mitogen-activated protein kinase activation in vascular smooth muscle cells.

  2005cited by this paper
• Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells.

  2001cited by this paper
• SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages.

  1999cited by this paper
• Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47.

  1999cited by this paper
• The pathogenesis of atherosclerosis: a perspective for the 1990s

  1993cited by this paper
• The FASEB Journal • Research Communication Identification and selection of cardiomyocytes during human embryonic stem cell differentiation

  year unknowncited by this paper

• Cardiac regeneration: The present state and future direction of human pluripotent stem cell therapy.

  2026cites this paper
• AI-guided laser purification of human iPSC-derived cardiomyocytes for next-generation cardiac cell manufacturing

  2025cites this paper
• Hypoimmunogenic hPSC-derived cardiac organoids for immune evasion and heart repair

  2025cites this paper
• Identification and Purification of Specific Cell Populations via ADAR Editing-Driven Synthetic Genetic Circuits.

  2025cites this paper
• Billion‐Scale Expansion of Functional hiPSC‐Derived Cardiomyocytes in Bioreactors Through Oxygen Control and Continuous Wnt Activation

  2025cites this paper
• High‐Resolution Imaging and Assessment of Vascular Network in Tri‐Lineage hiPSC‐Derived Cardiac Microtissues

  2025cites this paper
• Integrating synthetic biology to understand and engineer the heart, lung, blood, and sleep systems.

  2025cites this paper
• Cell Barcoding Reveals Lineage-dependent Outcomes in hiPSC Cardiac Differentiation

  2025influential citation
• Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timing

  2025cites this paper
• Purification technologies for induced pluripotent stem cell therapies

  2024cites this paper
• Proteomics applications in next generation induced pluripotent stem cell models

  2024cites this paper
• Improving human cardiac organoid design using transcriptomics

  2024cites this paper
• miR-24-3p secreted as extracellular vesicle cargo by cardiomyocytes inhibits fibrosis in human cardiac microtissues

  2024cites this paper
• FAST-STEM: A Human pluripotent stem cell engineering toolkit for rapid design-build-test-learn development of human cell-based therapeutic devices

  2024cites this paper
• 基于诱导多能干细胞治疗急性心肌梗死的临床前研究进展

  2024cites this paper
• Single-cell transcriptome analysis reveals CD34 as a marker of human sinoatrial node pacemaker cardiomyocytes

  2024cites this paper
• CD151 expression marks atrial- and ventricular- differentiation from human induced pluripotent stem cells

  2024cites this paper
• Gene correction and overexpression of TNNI3 improve impaired relaxation in engineered heart tissue model of pediatric restrictive cardiomyopathy

  2024cites this paper
• GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis

  2024cites this paper
• Transient Notch Activation Converts Pluripotent Stem Cell-Derived Cardiomyocytes Towards a Purkinje Fiber Fate

  2024cites this paper
• Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease

  2024cites this paper
• In Vitro Models of Cardiovascular Disease: Embryoid Bodies, Organoids and Everything in Between

  2024cites this paper
• Enriching Cardiomyocytes Derived from hiPSCs by Magnetic-Activated Cell Sorting (MACS).

  2024cites this paper
• Toward the latest advancements in cardiac regeneration using induced pluripotent stem cells (iPSCs) technology: approaches and challenges

  2024cites this paper
• Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors

  2023influential citation
• Verification of Therapeutic Effect through Accelerator Mass Spectrometry‐Based Single Cell Level Quantification of hESC‐Endothelial Cells Distributed into an Ischemic Model

  2023cites this paper
• Intracellular Molecules Induced Extracellular Peptide Self-Assembly for Efficient and Effective In Situ Cell Purification.

  2023cites this paper
• SIRPα: A key player in innate immunity

  2023cites this paper
• Recent advances in pluripotent stem cell-derived cardiac organoids and heart-on-chip applications for studying anti-cancer drug-induced cardiotoxicity

  2023influential citation
• Induced pluripotent stem cells for cardiovascular therapeutics: Progress and perspectives

  2023cites this paper
• Extracellular Vesicle–Encapsulated Adeno-Associated Viruses for Therapeutic Gene Delivery to the Heart

  2023cites this paper
• Engineering the maturation of stem cell-derived cardiomyocytes

  2023cites this paper
• Animal Disease Models and Patient-iPS-Cell-Derived In Vitro Disease Models for Cardiovascular Biology—How Close to Disease?

  2023cites this paper
• APLNR marks a cardiac progenitor derived with human induced pluripotent stem cells

  2023cites this paper
• Surfaceome mapping of primary human heart cells with CellSurfer uncovers cardiomyocyte surface protein LSMEM2 and proteome dynamics in failing hearts

  2023influential citation
• Engineered cardiac tissue model of restrictive cardiomyopathy for drug discovery

  2023cites this paper
• Cardiac Regenerative Therapy Using Human Pluripotent Stem Cells for Heart Failure: A State-of-the-Art Review.

  2023cites this paper
• Functional Activity of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes on a Mouse Renal Subcapsular Xenograft Model

  2023cites this paper
• Unlocking the Pragmatic Potential of Regenerative Therapies in Heart Failure with Next-Generation Treatments

  2023cites this paper
• Sensing context: Inhibitory receptors on non‐hematopoietic cells

  2023cites this paper
• How can we use stem cell-derived cardiomyocytes to understand the involvement of energetic metabolism in alterations of cardiac function?

  2023cites this paper
• A Pan-RNase Inhibitor Enabling CRISPR-mRNA Platforms for Engineering of Primary Human Monocytes

  2022cites this paper
• CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data

  2022cites this paper
• Cellular Heterogeneity of Pluripotent Stem Cell Derived Cardiomyocyte Grafts is Mechanistically Linked to Treatable Arrhythmias

  2022cites this paper
• The negative regulation of gene expression by microRNAs as key driver of inducers and repressors of cardiomyocyte differentiation

  2022cites this paper
• Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin

  2022cites this paper
• Xeno-Free Integrated Platform for Robust Production of Cardiomyocyte Sheets from hiPSCs

  2022cites this paper
• Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease.

  2022cites this paper
• Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances

  2022cites this paper
• Cardiovascular Regeneration via Stem Cells and Direct Reprogramming: A Review

  2022cites this paper
• Advances in Manufacturing Cardiomyocytes from Human Pluripotent Stem Cells.

  2022cites this paper
• Synthetic RNA-based post-transcriptional expression control methods and genetic circuits.

  2022cites this paper
• Functional Characterization of Endothelial Cells Differentiated from Porcine Epiblast Stem Cells

  2022cites this paper
• Stem Cell Studies in Cardiovascular Biology and Medicine: A Possible Key Role of Macrophages

  2022cites this paper
• Effect and application of cryopreserved three‐dimensional microcardiac spheroids in myocardial infarction therapy

  2022cites this paper
• High cardiomyocyte diversity in human early prenatal heart development

  2022cites this paper
• Cardiac Cell Therapy with Pluripotent Stem Cell-Derived Cardiomyocytes: What Has Been Done and What Remains to Do?

  2022cites this paper
• The Growth Hormone Releasing Hormone Signaling Pathway Governs Cardiomyocyte differentiation in human iPS cells

  2022cites this paper
• Purification of human iPSC-derived cells at large scale using microRNA switch and magnetic-activated cell sorting

  2022cites this paper
• Induced pluripotent stem cells for modeling Noonan, Noonan Syndrome with Multiple Lentigines, and Costello Syndromes

  2022cites this paper
• Signaling pathways regulate cardiovascular lineage commitment of hPSCs

  2022cites this paper
• PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem-cell-derived cardiomyocytes.

  2022cites this paper
• Engineering stem cell therapeutics for cardiac repair.

  2022cites this paper
• Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases

  2021influential citation
• Myosin light chain 2 marks differentiating ventricular cardiomyocytes derived from human embryonic stem cells

  2021cites this paper
• A dual cardiomyocyte reporter model derived from human pluripotent stem cells

  2021cites this paper
• Differentiation and Application of Human Pluripotent Stem Cells Derived Cardiovascular Cells for Treatment of Heart Diseases: Promises and Challenges

  2021influential citation
• iPSC modeling shows uncompensated mitochondrial mediated oxidative stress underlies early heart failure in hypoplastic left heart syndrome

  2021cites this paper
• Myocardial hypoxic stress mediates functional cardiac extracellular vesicle release.

  2021cites this paper
• In vitro model of ischemic heart failure using human induced pluripotent stem cell–derived cardiomyocytes

  2021cites this paper
• Cell surface markers for immunophenotyping human pluripotent stem cell-derived cardiomyocytes

  2021cites this paper
• Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics

  2021cites this paper
• PECAM-1 preserves cardiac function in pressure overload-induced biomechanical stress

  2021cites this paper
• Adhesion GPCR Latrophilin-2 Specifies Cardiac Lineage Commitment through CDK5, Src, and P38MAPK

  2021influential citation
• Therapeutic and Diagnostic Translation of Extracellular Vesicles in Cardiovascular Diseases

  2021cites this paper
• Induced pluripotent stem cell-derived cardiomyocytes

  2021cites this paper
• Oxygen Is an Ambivalent Factor for the Differentiation of Human Pluripotent Stem Cells in Cardiac 2D Monolayer and 3D Cardiac Spheroids

  2021cites this paper
• Messages from the heart.

  2021cites this paper
• Cardiac Differentiation of Human Pluripotent Stem Cells Using Defined Extracellular Matrix Proteins Reveals Essential Role of Fibronectin

  2021cites this paper
• DNA methylation in heart failure

  2021cites this paper
• Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac phenotype.

  2021cites this paper
• Most myopathic lamin variants aggregate: a functional genomics approach for assessing variants of uncertain significance

  2021cites this paper
• The Present State and Future Perspectives of Cardiac Regenerative Therapy Using Human Pluripotent Stem Cells

  2021cites this paper
• Production of functional cardiomyocytes and cardiac tissue from human induced pluripotent stem cells for regenerative therapy.

  2021cites this paper
• Transplantation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Mouse Myocardial Infarction Model.

  2021cites this paper
• Characterization of Ventricular and Atrial Cardiomyocyte Subtypes from Human-Induced Pluripotent Stem Cells.

  2021cites this paper
• Isolation of Cardiomyocytes Derived from Human Pluripotent Stem Cells Using miRNA Switches.

  2021cites this paper
• Downstream bioprocessing of human pluripotent stem cell‐derived therapeutics

  2021cites this paper
• Recent progress of iPSC technology in cardiac diseases

  2021cites this paper
• Cell Sources of Cardiomyocytes for Heart Repair

  2021cites this paper
• Application of FluoVolt Membrane Potential Dye for Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Differentiated via Embryoid Bodies.

  2021cites this paper
• RNA-Sequencing Analysis of Differentially Expressed Genes in Human iPSC-Derived Cardiomyocytes.

  2021cites this paper
• Application of Patient-Specific iPSCs for Modelling and Treatment of X-Linked Cardiomyopathies

  2021cites this paper
• Most myopathic lamin variants aggregate: a functional genomics approach for assessing variants of uncertain significance

  2021cites this paper
• ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes

  2021cites this paper
• Control of cardiomyocyte differentiation timing by intercellular signaling pathways.

  2021cites this paper
• PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

  2021cites this paper
• Cell type determination for cardiac differentiation occurs soon after seeding of human-induced pluripotent stem cells

  2021influential citation
• Identification and characterization of hPSC-derived FOXA2+ progenitor cells with ventricular cardiac differentiation potential

  2021cites this paper
• Modelling adverse drug reactions using induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs)

  2021cites this paper