Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Neurochemistry

• Publication date

  2010-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1471-4159.2010.06750.xPMID 20403082
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Plasma and brain concentrations of oral therapeutic doses of methylphenidate and their impact on brain monoamine content in mice.

  2009influential reference
• Role of prefrontal dopaminergic neurotransmission in glucocorticoid receptor‐mediated modulation of methamphetamine‐induced hyperactivity

  2009cited by this paper
• Behavioural and neurochemical abnormalities in mice lacking functional tachykinin-1 (NK1) receptors: a model of attention deficit hyperactivity disorder.

  2009cited by this paper
• Reinforcing and subjective effects of methylphenidate in adults with and without attention deficit hyperactivity disorder (ADHD)

  2009cited by this paper
• Chronic treatment with a dopamine uptake blocker changes dopamine and acetylcholine but not glutamate and GABA concentrations in prefrontal cortex, striatum and nucleus accumbens of the awake rat.

  2008cited by this paper
• Comparative benefits and harms of competing medications for adults with attention-deficit hyperactivity disorder: a systematic review and indirect comparison meta-analysis

  2008cited by this paper
• Ritanserin reverses repeated methamphetamine‐induced behavioral and neurochemical sensitization in mice

  2007influential reference
• Differential effects of adjunctive methylphenidate and citalopram on extracellular levels of serotonin, noradrenaline and dopamine in the rat brain.

  2007cited by this paper
• Effects of amphetamine isomers, methylphenidate and atomoxetine on synaptosomal and synaptic vesicle accumulation and release of dopamine and noradrenaline in vitro in the rat brain.

  2007cited by this paper
• Animal models concerning the role of dopamine in attention-deficit hyperactivity disorder.

  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• Methylphenidate preferentially increases catecholamine neurotransmission within the prefrontal cortex at low doses that enhance cognitive function.

  2006cited by this paper
• Attenuation by the 5-HT1A receptor agonist osemozotan of the behavioral effects of single and repeated methamphetamine in mice.

  2006influential reference
• Sensory-evoked potentials recordings from the ventral tegmental area, nucleus accumbens, prefrontal cortex, and caudate nucleus and locomotor activity are modulated in dose-response characteristics by methylphenidate.

  2006cited by this paper
• Subchronic milnacipran treatment increases basal extracellular noradrenaline concentrations in the medial prefrontal cortex of rats.

  2005cited by this paper
• Quantification and pharmacological characterization of dialysate levels of noradrenaline in the striatum of freely-moving rats: release from adrenergic terminals and modulation by α2-autoreceptors

  2004cited by this paper
• Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions.

  2004cited by this paper
• Quantification and pharmacological characterization of dialysate levels of noradrenaline in the striatum of freely-moving rats: release from adrenergic terminals and modulation by alpha2-autoreceptors.

  2004cited by this paper
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  2004influential reference
• Does stimulant therapy of attention‐deficit/hyperactivity disorder beget later substance abuse?

  2003cited by this paper
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  2003cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
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  2003cited by this paper
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  2002influential reference
• Mutation of the α2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine

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• Long-Term Effects of Stimulant Medications on the Brain: Possible Relevance to the Treatment of Attention Deficit Hyperactivity Disorder

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• Reboxetine modulates the firing pattern of dopamine cells in the ventral tegmental area and selectively increases dopamine availability in the prefrontal cortex.

  2001cited by this paper
• Hyperactivity and impaired response habituation in hyperdopaminergic mice.

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• Studies on the acute and chronic effects of reboxetine on extracellular noradrenaline and other monoamines in the rat brain

  1999cited by this paper
• Effect of alterations in extracellular norepinephrine on adrenoceptors: a microdialysis study in freely moving rats.

  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
• Comparative evaluation of [3H]WIN 35428 and [3H]GBR 12935 as markers of dopamine innervation density in brain

  1997cited by this paper
• Effects of Methylphenidate on Extracellular Dopamine, Serotonin, and Norepinephrine: Comparison with Amphetamine

  1997cited by this paper
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  1997cited by this paper
• Pharmacological profile of antidepressants and related compounds at human monoamine transporters.

  1997cited by this paper
• Chronic desipramine and fluoxetine differentially affect extracellular dopamine in the rat prefrontal cortex

  1996influential reference
• Novel halogenated analogs of tomoxetine that are potent and selective inhibitors of norepinephrine uptake in brain.

  1995cited by this paper
• Comparison of (R)‐[3H] Tomoxetine and (R/S)‐[3H] Nisoxetine Binding in Rat Brain

  1995cited by this paper
• Time course of bromocriptine induced excitation in the rat: behavioural and biochemical studies

  1995cited by this paper
• Localization of rat brain binding sites for [3H]tomoxetine, an enantiomerically pure ligand for norepinephrine reuptake sites.

  1993cited by this paper
• Prazosin modulates the firing pattern of dopamine neurons in rat ventral tegmental area.

  1993cited by this paper
• Blockade of the Noradrenaline Carrier Increases Extracellular Dopamine Concentrations in the Prefrontal Cortex: Evidence that Dopamine Is Taken up In Vivo by Noradrenergic Terminals

  1990cited by this paper
• Studies on the Acute and Chronic Effects of Sandostatin® in Acromegaly

  1988cited by this paper

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