Crystal structure analysis and molecular model of human C3a anaphylatoxin.

No abstract is available for this paper.

• Publication year

  1980

• Venue

  Hoppe-Seyler´s Zeitschrift für physiologische Chemie

• Publication date

  1980-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1515/BCHM2.1980.361.2.1389PMID 7439885
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Purification and crystallization of human anaphylatoxin, C3a.

  1980cited by this paper
• Novel cleavage products of the third component of human complement.

  1980cited by this paper
• Activation of the complement system by antibody-antigen complexes: the classical pathway.

  1979cited by this paper
• Third component of human complement: structural analysis of the polypeptide chains of C3 and C3b.

  1979cited by this paper
• C3e: an acidic fragment of human C3 with leukocytosis-inducing activity.

  1979cited by this paper
• The isolation and characterization of bovine C4a, an activation fragment of the fourth component of complement.

  1979cited by this paper
• Purification, characterization, and amino acid sequence of rat anaphylatoxin (C3a).

  1978cited by this paper
• A graphics model building and refinement system for macromolecules

  1978cited by this paper
• Crystallization, crystal structure analysis and atomic model of the complex formed by a human Fc fragment and fragment B of protein A from Staphylococcus aureus.

  1978cited by this paper
• Chemical aspects of the serum anaphylatoxins.

  1978cited by this paper
• The crystal structure of wheat germ agglutinin at 2-2 A resolution.

  1977cited by this paper
• Mechanism of action of the C3b inactivator: requirement for a high molecular weight cofactor (C3b-C4bINA cofactor) and production of a new C3b derivative (C3b').

  1977cited by this paper
• Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution

  1977cited by this paper
• Crystallographic structure studies of an IgG molecule and an Fc fragment

  1976cited by this paper
• Crystallographic structural studies of a human Fc fragment. II. A complete model based on a Fourier map at 3.5 A resolution.

  1976cited by this paper
• Circular dichroism of C3a anaphylatoxin. Effects of pH, heat, guanidinium chloride, and mercaptoethanol on conformation and function.

  1975cited by this paper
• Physico-chemical and antigenic properties of human C3.

  1975cited by this paper
• Third component of complement (C3): structural properties in relation to functions.

  1975cited by this paper
• Refinement of setting angles in screenless film methods

  1975cited by this paper
• Complement.

  1975cited by this paper
• ISOLATION OF A FRAGMENT (C3a) OF THE THIRD COMPONENT OF HUMAN COMPLEMENT CONTAINING ANAPHYLATOXIN AND CHEMOTACTIC ACTIVITY AND DESCRIPTION OF AN ANAPHYLATOXIN INACTIVATOR OF HUMAN SERUM

  1969cited by this paper

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  2020cites this paper
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  2020cites this paper
• Structure and activity of Clr and Cls

  2016cites this paper
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• C4a: An Anaphylatoxin in Name Only

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• Cobra Venom Factor: The Unique Component of Cobra Venom That Activates the Complement System

  2015cites this paper
• Evolution of the complement system C3 gene in Antarctic teleosts.

  2015cites this paper
• Efficient chemical synthesis of human complement protein C3a.

  2013cites this paper
• Macrophages and Related Cells

  2013cites this paper
• Human C3a and C3a desArg anaphylatoxins have conserved structures, in contrast to C5a and C5a desArg

  2013cites this paper
• Downsizing a human inflammatory protein to a small molecule with equal potency and functionality

  2013cites this paper
• Interplay between invertebrate C3a with vertebrate macrophages: functional characterization of immune activities of amphioxus C3a.

  2013cites this paper
• The Effects of Selenium on Polyunsaturated Fatty Acids of Diasporangium jonesianum

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• Putting the structure into complement.

  2012cites this paper
• De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation.

  2012cites this paper
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• Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer

  2011cites this paper
• Structure of human desArg-C5a.

  2010cites this paper
• Update 1 of: Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure.

  2010cites this paper
• Molecular mechanisms of complement evasion: learning from staphylococci and meningococci

  2010cites this paper
• [The efficiency of the bactericidal action of serum raised by complement and lysozyme against bacteria which avoid the immunological response of higher organisms].

  2009cites this paper
• Cyclic disulfide analogues of the complement component C3a. Synthesis and conformational investigations.

  2009cites this paper
• Overcoming the Key Challenges in De Novo Protein Design: Enhancing Computational Efficiency and Incorporating True Backbone Flexibility

  2008cites this paper
• Denaturation and unfolding of human anaphylatoxin C3a: an unusually low covalent stability of its native disulfide bonds.

  2008cites this paper
• Identification of ligand effector binding sites in transmembrane regions of the human G protein‐coupled C3a receptor

  2008influential citation
• Complement driven by conformational changes

  2008cites this paper
• Rational design of antimicrobial C3a analogues with enhanced effects against Staphylococci using an integrated structure and function-based approach.

  2008cites this paper
• Bioinformatics studies on sequence, structure and functional relationships of proteins involved in the complement system

  2007cites this paper
• Antimicrobial C3a--biology, biophysics, and evolution.

  2007cites this paper
• The Structure of OMCI, a Novel Lipocalin Inhibitor of the Complement System

  2007cites this paper
• The role of the complement anaphylatoxins in the recruitment of eosinophils.

  2007cites this paper
• Deciphering complement mechanisms: the contributions of structural biology.

  2007influential citation
• Structural insights into the central complement component C3.

  2007cites this paper
• Preservation of Antimicrobial Properties of Complement Peptide C3a, from Invertebrates to Humans*

  2007cites this paper
• Conformational complexity of complement component C3.

  2006cites this paper
• Structural transitions of complement component C3 and its activation products

  2006cites this paper
• Structures of complement component C3 provide insights into the function and evolution of immunity

  2005cites this paper
• Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure.

  2005cites this paper
• The Structures of Human Complement Fragments C3d and C4Ad and the Functional Insights That They Have Provided

  2005cites this paper
• Characterization of a C3-like cDNA in a coral: phylogenetic implications

  2005cites this paper
• Structure of the Anaphylatoxins C3a and C5a

  2005cites this paper
• The Building Blocks of the Complement System

  2005cites this paper
• Structural studies of SCR domains in multidomain complement proteins.

  2003cites this paper
• Fibulins: a versatile family of extracellular matrix proteins

  2003cites this paper
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  2003cites this paper
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  2003cites this paper
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  2002cites this paper
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  2001cites this paper
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  2001cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1998cites this paper
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  1998cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997influential citation
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  1996cites this paper
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  1996cites this paper
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  1996cites this paper
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  1994cites this paper
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  1994cites this paper
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  1994cites this paper
• Crystallization of human methylamine-treated complement C3 and C3b.

  1994cites this paper
• Site-specific mutagenesis of residues in the human C5a anaphylatoxin which are involved in possible interaction with the C5a receptor.

  1994cites this paper
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  1994cites this paper
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  1993cites this paper
• Tryptophan mutants of human C5a anaphylatoxin: a fluorescence anisotropy decay and energy transfer study.

  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
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  1993cites this paper
• Use of synthetic peptides in exploring and modifying complement reactivities

  1993cites this paper
• Biologic activity of synthetic analogues of C5a anaphylatoxin.

  1992cites this paper
• Identification of the disulfide bonds of the human complement component C3

  1992cites this paper
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  1992cites this paper
• Chapter 29. Macromolecular X-Ray Crystallography and NMR as Tools for Structure-based Drug Design

  1992cites this paper
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  1992cites this paper
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  1991cites this paper
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  1991cites this paper
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  1991cites this paper
• The complete exon-intron structure of a human complement component C4A gene. DNA sequences, polymorphism, and linkage to the 21-hydroxylase gene.

  1991cites this paper
• The structure of a complex of recombinant hirudin and human alpha-thrombin.

  1990cites this paper