Genomic cloning and chromosomal assignment of rat regucalcin gene

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Molecular and Cellular Biochemistry

• Publication date

  1995-10-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF01322338PMID 8569761
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Specific species and tissue differences for the gene expression of calcium-binding protein regucalcin

  1995cited by this paper
• Expression of hepatic calcium-binding protein regucalcin mRNA is elevated by refeeding of fasted rats: Involvement of glucose, insulin and calcium as stimulating factors

  1995cited by this paper
• 17β-Estradiol stimulates the expression of hepatic calcium-binding protein regucalcin mRNA in rats

  1995cited by this paper
• Application of fluorescence in situ hybridization in genome analysis of the mouse

  1995cited by this paper
• Expression of hepatic calcium-binding protein regucalcin mRNA is decreased by phenobarbital administration in rats

  1994cited by this paper
• Hepatic calcium-binding protein regucalcin is released into the serum of rats administered orally carbon tetrachloride

  1994cited by this paper
• Expression of calcium-binding protein regucalcin mRNA in rat liver is stimulated by calcitonin: The hormonal effect is mediated through calcium

  1994cited by this paper
• Serum release of hepatic calcium-binding protein regucalcin by liver injury with galactosamine administration in rats

  1994cited by this paper
• Molecular cloning and sequencing of the cDNA coding for a calcium‐binding protein regucalcin from rat liver

  1993cited by this paper
• Expression of hepatic calcium‐binding protein regucalcin mRNA is mediated through Ca2+/calmodulin in rat liver

  1993cited by this paper
• A novel Ca^ -binding protein regucalcin and calcium inhibition: regulatory role in liver cell function.

  1992cited by this paper
• Calcium administration stimulates the expression of calcium‐binding protein regucalcin mRNA in rat liver

  1992cited by this paper
• Location of the mouse complement factor H gene (cfh) by FISH analysis and replication R-banding.

  1992cited by this paper
• Inhibitory effect of calcium-binding protein regucalcin on Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase activity in rat liver cytosol

  1991cited by this paper
• Inhibitory effect of calcium‐binding protein regucalcin on Ca2+‐activated DNA fragmentation in rat liver nuclei

  1991cited by this paper
• Inhibitory effect of calcium-binding protein regucalcin on protein kinase C activity in rat liver cytosol.

  1990cited by this paper
• High resolution chromosome banding in the Norway rat, Rattus norvegicus.

  1989influential reference
• The high resolution R-banded karyotype of Rattus norvegicus.

  1987influential reference
• Studies and perspectives of protein kinase C.

  1986cited by this paper
• Dideoxy sequencing method using denatured plasmid templates.

  1986cited by this paper
• Identifier sequences are transcribed specifically in brain

  1984cited by this paper
• Characterization of genomic poly(dT-dG).poly(dC-dA) sequences: structure, organization, and conformation

  1984cited by this paper
• The role of calcium ions in the mechanism of action of alpha-adrenergic agonists in rat liver.

  1984cited by this paper
• A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

  1983influential reference
• A catalogue of splice junction sequences.

  1982cited by this paper
• Properties of calcium-binding protein isolated from the soluble fraction of normal rat liver.

  1981cited by this paper
• Role of calcium in the hormonal regulation of liver metabolism.

  1981cited by this paper
• Calmodulin plays a pivotal role in cellular regulation.

  1980cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper

• Threonine and tyrosine kinase promotes multiple myeloma progression by regulating regucalcin expression.

  2025cites this paper
• Extracellular Regucalcin: A Potent Suppressor in the Cancer Cell Microenvironment

  2025cites this paper
• Extracellular regucalcin reveals anti-cancer activity by suppressing cell growth and metastatic activity by blocking EGF signaling pathway in human glioblastoma cells in vitro.

  2025cites this paper
• Functional pleiotropy of calcium binding protein Regucalcin in signaling and diseases.

  2022cites this paper
• The overexpressed regucalcin represses the growth via regulating diverse pathways linked to EGF signaling in human ovarian cancer SK-OV-3 cells: Involvement of extracellular regucalcin.

  2022cites this paper
• Extracellular Regucalcin Suppresses the Growth, Migration, Invasion, and Adhesion of Metastatic Human Prostate Cancer Cells

  2022cites this paper
• Overexpression of regucalcin blocks the migration, invasion, and bone metastatic activity of human prostate cancer cells: Crosstalk between cancer cells and bone cells

  2022cites this paper
• The calcium channel agonist Bay K 8644 promotes the growth of human liver cancer HepG2 cells in vitro: suppression with overexpressed regucalcin

  2020cites this paper
• Extracellular regucalcin suppresses colony formation and growth independent of tumor suppressor p53 in human mammary epithelial cells.

  2020cites this paper
• Progression-free survival of prostate cancer patients is prolonged with a higher regucalcin expression in the tumor tissues: Overexpressed regucalcin suppresses the growth and bone activity in human prostate cancer cells

  2020cites this paper
• Serum regucalcin is a useful indicator of liver injury severity in patients with hepatitis B virus-related liver diseases

  2019cites this paper
• Overexpression of Regucalcin Suppresses the Growth of Human Osteosarcoma Cells in Vitro: Repressive Effect of Extracellular Regucalcin

  2019cites this paper
• Prolonged survival of renal cancer patients is concomitant with a higher regucalcin gene expression in tumor tissues: Overexpression of regucalcin suppresses the growth of human renal cell carcinoma cells in vitro.

  2018cites this paper
• Regucalcin confers resistance to amyloid‐β toxicity in neuronally differentiated PC12 cells

  2018cites this paper
• Characterization of the testicular transcriptome of transgenic rat overexpressing regucalcin: insights into (in)fertility

  2018cites this paper
• Prolonged survival of patients with colorectal cancer is associated with a higher regucalcin gene expression: Overexpression of regucalcin suppresses the growth of human colorectal carcinoma cells in vitro.

  2018cites this paper
• Involvement of Regucalcin in Human Carcinogenesis Prevention

  2017cites this paper
• Biological evidence of the protective role of regucalcin in breast cancer

  2016cites this paper
• Increased regucalcin gene expression extends survival in breast cancer patients: Overexpression of regucalcin suppresses the proliferation and metastatic bone activity in MDA-MB-231 human breast cancer cells in vitro.

  2016cites this paper
• Regucalcin , an inhibitor of cell signaling and transcription activity , is involved in suppression of human carcinogenesis

  2016cites this paper
• Prolonged survival in pancreatic cancer patients with increased regucalcin gene expression: Overexpression of regucalcin suppresses the proliferation in human pancreatic cancer MIA PaCa-2 cells in vitro.

  2016cites this paper
• Exogenous regucalcin suppresses the proliferation of human breast cancer MDA-MB-231 bone metastatic cells in vitro

  2015cites this paper
• Exogenous regucalcin suppresses the proliferation of human breast cancer MDA-MB-231 bone metastatic cells in vitro.

  2015cites this paper
• Suppressive effects of exogenous regucalcin on the proliferation of human pancreatic cancer MIA PaCa-2 cells in vitro.

  2015cites this paper
• The Regucalcin Gene may be a Key in Depression of Human Carcinogenesis

  2015cites this paper
• Regucalcin Transgenic Rat: A Novel Animal Model for Metabolic Disorder Associated with Osteoporosis

  2015cites this paper
• Involvement of Regucalcin in Protein Synthesis and Proteolysis: Regulation of the Enzyme Activity in the Cytoplasm and Nucleus

  2015cites this paper
• Involvement of regucalcin as a suppressor protein in human carcinogenesis: insight into the gene therapy

  2015cites this paper
• The role of regucalcin in bone homeostasis: involvement as a novel cytokine.

  2014cites this paper
• The SCF/c-KIT system and imatinib actions in prostate cancer: a cross-talk with RGN?

  2014cites this paper
• Regulatory role of regucalcin in heart calcium signaling: Insight into cardiac failure (Review)

  2014cites this paper
• The suppression of regucalcin gene expression may lead to hepatocarcinogenesis

  2014cites this paper
• Alternatively spliced variants of the regucalcin gene in various human normal and tumor tissues.

  2014cites this paper
• Regucalcin as a potential biomarker for metabolic and neuronal diseases

  2014cites this paper
• Suppressive role of regucalcin in liver cell proliferation: involvement in carcinogenesis

  2013cites this paper
• Role of regucalcin in cell nuclear regulation: involvement as a transcription factor

  2013cites this paper
• Involvement of regucalcin in lipid metabolism and diabetes.

  2013cites this paper
• Calcium Regulatory Protein, Regucalcin, may be a Key Molecule in Brain Disease

  2013cites this paper
• Suppressive role of regucalcin in protein output in liver cells

  2013cites this paper
• The anti-apoptotic effect of regucalcin is mediated through multisignaling pathways

  2013cites this paper
• Hormonal regulation of regucalcin gene expression: involvement in cell metabolism

  2013cites this paper
• Androgens in breast cancer cells physiology A connection with calcium homeostasis

  2012cites this paper
• Regucalcin, cell signaling-related protein: its multifunctional role in kidney cell regulation

  2012cites this paper
• Role of regucalcin in brain calcium signaling: involvement in aging.

  2012cites this paper
• Regucalcin: new development on biotechnology

  2012cites this paper
• Regucalcin, a calcium-binding protein with a role in male reproduction?

  2012cites this paper
• Regucalcin and cell regulation: role as a suppressor protein in signal transduction

  2011cites this paper
• Regucalcin and metabolic disorders: osteoporosis and hyperlipidemia are induced in regucalcin transgenic rats

  2010cites this paper
• The transcriptional regulation of regucalcin gene expression

  2010cites this paper
• Novel protein RGPR-p117: its role as the regucalcin gene transcription factor

  2009cites this paper
• Regucalcin increases Ca2+‐ATPase activity in the mitochondria of brain tissues of normal and transgenic rats

  2008cites this paper
• Hormonal regulation of regucalcin mRNA expression in osteoblastic MC3T3-E1 cells.

  2008cites this paper
• Overexpression of regucalcin suppresses gene expression of insulin signaling-related proteins in cloned rat hepatoma H4-II-E cells: involvement of insulin resistance.

  2007cites this paper
• Suppression of regucalcin mRNA expression in the hearts of rats administered with free radical compound: the administration-induced death is accelerated in regucalcin transgenic rats.

  2007cites this paper
• Change in lipid components in the adipose and liver tissues of regucalcin transgenic rats with increasing age: suppression of leptin and adiponectin gene expression.

  2007cites this paper
• Overexpression of regucalcin suppresses cell response for tumor necrosis factor‐α or transforming growth factor‐β1 in cloned normal rat kidney proximal tubular epithelial NRK52E cells

  2007cites this paper
• Overexpression of regucalcin enhances glucose utilization and lipid production in cloned rat hepatoma H4‐II‐E cells: Involvement of insulin resistance

  2006cites this paper
• Overexpression of regucalcin enhances its nuclear localization and suppresses L‐type Ca2+ channel and calcium‐sensing receptor mRNA expressions in cloned normal rat kidney proximal tubular epithelial NRK52E cells

  2006cites this paper
• Regucalcin increases Ca2+-ATPase activity in the heart mitochondria of normal and regucalcin transgenic rats.

  2006cites this paper
• Regulatory effect of exogenous regucalcin on cell function in osteoblastic MC3T3-E1 cells: involvement of intracellular signaling factor.

  2006cites this paper
• Overexpression of regucalcin suppresses cell death and apoptosis in cloned rat hepatoma H4‐II‐E cells induced by insulin or insulin‐like growth factor‐I

  2005cites this paper
• Overexpression of regucalcin suppresses cell proliferation of cloned normal rat kidney proximal tubular epithelial NRK52E cells.

  2005cites this paper
• Hormonal regulation on regucalcin mRNA expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells

  2005cites this paper
• Overexpression of regucalcin suppresses apoptotic cell death in cloned normal rat kidney proximal tubular epithelial NRK52E cells: Change in apoptosis‐related gene expression

  2005cites this paper
• Regucalcin stimulates osteoclast‐like cell formation in mouse marrow cultures

  2005cites this paper
• Overexpression of regucalcin suppresses cell proliferation in cloned rat hepatoma H4‐II‐E cells: Involvement of intracellular signaling factors and cell cycle‐related genes

  2005cites this paper
• Role of regucalcin in maintaining cell homeostasis and function (review).

  2005cites this paper
• Suppressive effect of regucalcin on cell differentiation and mineralization in osteoblastic MC3T3‐E1 cells

  2005cites this paper
• Overexpression of regucalcin suppresses apoptotic cell death in the cloned rat hepatoma H4-II-E cells induced by a naturally occurring isothiocyanate sulforaphane.

  2005cites this paper
• Tissue-specific binding of nuclear factors to the 5′-flanking region of rat gene for calcium-binding protein regucalcin

  2004cites this paper
• Expression of regucalcin in rat bone marrow cells: involvement of osteoclastic bone resorption in regucalcin transgenic rats.

  2004cites this paper
• Regucalcin increases superoxide dismutase activity in the heart cytosol of normal and regucalcin transgenic rats.

  2004cites this paper
• Overexpression of regucalcin suppresses cell death in cloned rat hepatoma H4‐II‐E cells induced by tumor necrosis factor‐α or thapsigargin

  2004cites this paper
• Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats.

  2004cites this paper
• Regucalcin increases superoxide dismutase activity in rat liver cytosol.

  2004cites this paper
• Expression of calcium-binding protein regucalcin mRNA in fetal rat liver is stimulated by calcium administration

  2004cites this paper
• Overexpression of regucalcin suppresses cell death and apoptosis in cloned rat hepatoma H4‐II‐E cells induced by lipopolysaccharide, PD 98059, dibucaine, or Bay K 8644

  2004cites this paper
• Bone loss in regucalcin transgenic rats: enhancement of osteoclastic cell formation from bone marrow of rats with increasing age.

  2004cites this paper
• Stimulatory effect of calcium administration on regucalcin mRNA expression is attenuated in the kidney cortex of rats ingested with saline

  2004cites this paper
• Hyperlipidemia is induced in regucalcin transgenic rats with increasing age.

  2004cites this paper
• Suppressive effect of regucalcin on protein phosphatase activity in the heart cytosol of normal and regucalcin transgenic rats.

  2004cites this paper
• Novel protein RGPR‐p117: The gene expression in physiologic state and the binding activity to regucalcin gene promoter region in rat liver

  2003cites this paper
• Inhibitory role of regucalcin in the regulation of nitric oxide synthase activity in rat brain cytosol: involvement of aging.

  2003cites this paper
• Structure and evolution of the luciferin‐regenerating enzyme (LRE) gene from the firefly Photinus pyralis

  2003cites this paper
• Role of endogenous regucalcin in bone metabolism: bone loss is induced in regucalcin transgenic rats.

  2002cites this paper
• Molecular cloning and expression of the cDNAs encoding luciferin-regenerating enzyme from Luciola cruciata and Luciola lateralis.

  2002cites this paper
• Role of regucalcin as an activator of sarcoplasmic reticulum Ca2+‐ATPase activity in rat heart muscle

  2002cites this paper
• Role of endogenous regucalcin in transgenic rats: Suppression of kidney cortex cytosolic protein phosphatase activity and enhancement of heart muscle microsomal Ca2+‐ATPase activity

  2002cites this paper
• Potential role of regucalcin as a specific biochemical marker of chronic liver injury with carbon tetrachloride administration in rats

  2002cites this paper
• Identification of transcription factor in the promoter region of rat regucalcin gene: Binding of nuclear factor I‐A1 to TTGGC motif

  2002cites this paper
• Suppressive role of endogenous regucalcin in the enhancement of protein kinase activity with proliferation of cloned rat hepatoma cells (H4‐II‐E)

  2001cites this paper
• Stimulatory effect of regucalcin on mitochondrial ATP‐dependent calcium uptake activity in rat kidney cortex

  2001cites this paper
• Regulatory role of endogenous regucalcin in the enhancement of nuclear deoxyribonuleic acid synthesis with proliferation of cloned rat hepatoma cells (H4‐II‐E)

  2001cites this paper
• Involvement of nuclear factor-I (NF1) binding motif in the regucalcin gene expression of rat kidney cortex: The expression is suppressed by cisplatin administration

  2001cites this paper
• Enhancement of protein tyrosine phosphatase activity in the proliferation of cloned rat hepatoma H4-II-E cells: suppressive role of endogenous regucalcin.

  2000cites this paper
• The role of regucalcin in nuclear regulation of regenerating liver.

  2000cites this paper
• Intracellular signaling factors--enhanced hepatic nuclear protein binding to TTGGC sequence in the rat regucalcin gene promoter: involvement of protein phosphorylation.

  2000cites this paper
• The gene of Ca2+-binding protein regucalcin is highly conserved in vertebrate species.

  2000cites this paper
• Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.

  2000cites this paper
• Role of regucalcin in calcium signaling.

  2000cites this paper