The immunogenicity of tumor cell death

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Current Opinion in Oncology

• Publication date

  2009-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/CCO.0b013e32831bc375PMID 19125021
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tumor cell metabolism: cancer's Achilles' heel.

  2008cited by this paper
• Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein.

  2008cited by this paper
• Molecular characteristics of immunogenic cancer cell death

  2008cited by this paper
• Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin

  2008cited by this paper
• The anticancer immune response: indispensable for therapeutic success?

  2008cited by this paper
• The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death

  2008cited by this paper
• NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy.

  2008cited by this paper
• Immunological aspects of cancer chemotherapy

  2008cited by this paper
• Calreticulin exposure dictates the immunogenicity of cancer cell death

  2007cited by this paper
• Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

  2007cited by this paper
• Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications.

  2007cited by this paper
• Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

  2007cited by this paper
• Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference

  2007cited by this paper
• Inhibitory effect of tumor cell-derived lactic acid on human T cells.

  2007cited by this paper
• Calreticulin exposure is required for the immunogenicity of γ-irradiation and UVC light-induced apoptosis

  2007cited by this paper
• IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-κB activation

  2007cited by this paper
• Indoleamine 2,3-dioxygenase and tumor-induced tolerance.

  2007cited by this paper
• Ecto‐calreticulin in immunogenic chemotherapy

  2007cited by this paper
• From cancer immunosurveillance to cancer immunotherapy

  2007cited by this paper
• Death, danger, and immunity: an infernal trio

  2007cited by this paper
• The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

  2007cited by this paper
• High‐mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity

  2007cited by this paper
• Recognition ligands on apoptotic cells: a perspective

  2006cited by this paper
• Pentraxins as a key component of innate immunity.

  2006cited by this paper
• Cancer despite immunosurveillance: immunoselection and immunosubversion

  2006cited by this paper
• DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

  2005cited by this paper
• The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

  2005cited by this paper
• Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

  2005cited by this paper
• The immune response under stress: the role of HSP-derived peptides.

  2004cited by this paper
• New aspects of natural-killer-cell surveillance and therapy of cancer

  2002cited by this paper
• Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA.

  1999cited by this paper
• Natural adjuvants: Endogenous activators of dendritic cells

  1999cited by this paper
• Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

  1998cited by this paper
• Immunological Aspects of Cancer Chemotherapy

  1980cited by this paper

• Emerging roles of apoptotic bodies in immune homeostasis and oral disease therapeutics

  2025cites this paper
• Therapeutic targeting of cell death-immune crosstalk in cancer to rewire the tumor immune microenvironment

  2025cites this paper
• Advancements in research and clinical management of interstitial lung injury associated with ADC drugs administration in breast cancer

  2024cites this paper
• Auger emitter in combination with Olaparib suppresses tumor growth via promoting antitumor immune responses in pancreatic cancer

  2024cites this paper
• Pyroptosis and chemical classification of pyroptotic agents

  2024cites this paper
• Manganese ion gradient liposomes modified by disulfide bond enhance cellular uptake and tumor immunity

  2023cites this paper
• Exploiting immunostimulatory mechanisms of immunogenic cell death to develop membrane-encapsulated nanoparticles as a potent tumor vaccine

  2023cites this paper
• Effects of Electrochemotherapy on Immunologically Important Modifications in Tumor Cells

  2023cites this paper
• Combining energy-based focal ablation and immune checkpoint inhibitors: preclinical research and clinical trials

  2023cites this paper
• Immune checkpoint inhibition: a future guided by radiology

  2023cites this paper
• Pyroptosis Provides New Strategies for the Treatment of Cancer

  2023cites this paper
• Involvement of splenic marginal zone macrophages in the recognition of systemically administered phosphatidylserine-coated liposomes in mice.

  2022cites this paper
• Systemic Delivery of an Adjuvant CXCR4-CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy.

  2022cites this paper
• Electroporation and Immunotherapy—Unleashing the Abscopal Effect

  2022influential citation
• The Lymphatic Endothelium in the Context of Radioimmuno-Oncology

  2022cites this paper
• Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer

  2022cites this paper
• Molecular subtypes and a prognostic model for hepatocellular carcinoma based on immune- and immunogenic cell death-related lncRNAs

  2022cites this paper
• Zoledronic Acid-Gadolinium Coordination Polymer Nanorods for Improved Tumor Radioimmunotherapy by Synergetically Inducing Immunogenic Cell Death and Reprogramming the Immunosuppressive Microenvironment.

  2021cites this paper
• Molekulare Prädiktoren des Tumoransprechens auf neoadjuvante Radiochemotherapie des Rektumkarzinoms

  2021cites this paper
• Immunogenic Cell Death Induced by Chemoradiotherapy of Novel pH-Sensitive Cargo-Loaded Polymersomes in Glioblastoma

  2021cites this paper
• Chemotherapeutic drug-induced immunogenic cell death for nanomedicine-based cancer chemo-immunotherapy.

  2021cites this paper
• Endoplasmic Reticulum Chaperones in Viral Infection: Therapeutic Perspectives

  2021cites this paper
• Sequentially pH-Responsive Drug-Delivery Nanosystem for Tumor Immunogenic Cell Death and Cooperating with Immune Checkpoint Blockade for Efficient Cancer Chemoimmunotherapy.

  2021cites this paper
• Radioimmunotherapy: future prospects from the perspective of brachytherapy

  2021cites this paper
• Systemic delivery of a CXCR4-CXCL12 signaling inhibitor encapsulated in synthetic protein nanoparticles for glioma immunotherapy

  2021cites this paper
• Transarterial Radioembolization Versus Systemic Treatment for Hepatocellular Carcinoma with Macrovascular Invasion: Analysis of the U.S. National Cancer Database

  2021cites this paper
• Role of pyroptosis in cancer cells and clinical applications.

  2021cites this paper
• Correlation between hematological parameters and outcome in patients with locally advanced cervical cancer treated by concomitant chemoradiotherapy

  2020cites this paper
• Calreticulin exploits TGF‐β for extracellular matrix induction engineering a tissue regenerative process

  2020cites this paper
• Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

  2020cites this paper
• Luciferase-assisted detection of extracellular ATP and ATP metabolites during immunogenic death of cancer cells.

  2019cites this paper
• Immunotherapy and the Interventional Oncologist: Challenges and Opportunities-A Society of Interventional Oncology White Paper.

  2019cites this paper
• Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer

  2019cites this paper
• Targeted BiTE Expression by an Oncolytic Vector Augments Therapeutic Efficacy Against Solid Tumors

  2018cites this paper
• Nanopulse Stimulation (NPS) Induces Tumor Ablation and Immunity in Orthotopic 4T1 Mouse Breast Cancer: A Review

  2018cites this paper
• Local Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine

  2018influential citation
• Novel anthracyclines with enhanced immunogenic effects against drug resistant osteosarcoma cells

  2018cites this paper
• Light It Up: A Pre-Clinical Fluorescent Model to Illustrate Immunogenic Cell Death

  2018cites this paper
• Tumor reductive therapies and antitumor immunity.

  2017cites this paper
• Tumor reductive therapies and antitumor immunity

  2017cites this paper
• Danger signals: Chemotherapy enhancers?

  2017cites this paper
• Upregulated ectonucleotidases in FADD- and RIP1-deficient Jurkat leukemia cells counteract extracellular ATP/AMP accumulation via pannexin-1 channels during chemotherapeutic drug- induced apoptosis

  2017cites this paper
• Alpha-integrin expression and function modify chemoresistance and immunogenicity of acute lymphoblastic leukemia

  2017cites this paper
• Use of nanotechnology for improved pharmacokinetics and activity of immunogenic cell death inducers used in cancer chemotherapy

  2017cites this paper
• Up-regulated Ectonucleotidases in Fas-Associated Death Domain Protein– and Receptor-Interacting Protein Kinase 1–Deficient Jurkat Leukemia Cells Counteract Extracellular ATP/AMP Accumulation via Pannexin-1 Channels during Chemotherapeutic Drug-Induced Apoptosis

  2017cites this paper
• Combining dendritic cells and B cells for presentation of oxidised tumour antigens to CD8+ T cells

  2017cites this paper
• Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses

  2017cites this paper
• Efferocytosis of dying cells differentially modulate immunological outcomes in tumor microenvironment

  2017cites this paper
• Two Heads Are Better Than One: The Combination of Dendritic Cells & B Cells Yields An Improved T Cell Response Over Dendritic Cells Alone When Presenting Tumour Lysate Antigens

  2016cites this paper
• T-cell mediated anti-tumor immunity after photodynamic therapy: why does it not always work and how can we improve it?

  2015cites this paper
• Autophagy, a major adaptation pathway shaping cancer cell death and anticancer immunity responses following photodynamic therapy

  2015cites this paper
• Optimisation d'un vaccin thérapeutique dans les tumeurs des voies aérodigestives supérieures associées aux papillomavirus : rôle de l'induction d'une immunité muqueuse et de la combinaison à la radiothérapie

  2015cites this paper
• ANTI-TUMOR IMMUNE RESPONSES INDUCED BY RADIOTHERAPY: A REVIEW.

  2015cites this paper
• Autophagy Induced by Photodynamic Therapy (PDT): Shaping Resistance Against Cell Death and Anti-Tumor Immunity

  2015cites this paper
• Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation

  2015cites this paper
• Tumor infiltrating CD8+ T lymphocyte count is independent of tumor TLR9 status in treatment naïve triple negative breast cancer and renal cell carcinoma

  2015cites this paper
• Modeling the Specific CD4+ T Cell Response against a Tumor Neoantigen

  2015cites this paper
• Resistance to Photodynamic Therapy in Cancer

  2015cites this paper
• Mechanisms of Nanosecond Pulsed Electric Field (NsPEF)-Induced Cell Death in Cells and Tumors

  2015cites this paper
• Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

  2015influential citation
• Mechanisms of Nanosecond Pulsed Electric Field (NsPEF)-Induced Cell Death in Cells and Tumors

  2015cites this paper
• RIG-I Enhanced Interferon Independent Apoptosis upon Junin Virus Infection

  2014cites this paper
• A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

  2014cites this paper
• The Progression of Cell Death Affects the Rejection of Allogeneic Tumors in Immune-Competent Mice – Implications for Cancer Therapy

  2014cites this paper
• Neonatal Fc receptors for IgG drive CD8+ T cell-mediated anti-cancer immunosurveillance at tolerogenic mucosal sites

  2014cites this paper
• Chemotherapeutic Drugs Induce ATP Release via Caspase-gated Pannexin-1 Channels and a Caspase/Pannexin-1-independent Mechanism*

  2014cites this paper
• Co-expression of cancer testis antigens and topoisomerase 2-alpha in triple negative breast carcinomas.

  2014cites this paper
• Proposed mechanisms of action for prostate cancer vaccines

  2013cites this paper
• Antiapoptotic activity of argon and xenon

  2013cites this paper
• A calreticulin/gC1qR complex prevents cells from dying: a conserved mechanism from arthropods to humans.

  2013cites this paper
• Caractérisation biochimique et fonctionnelle de nouveaux anticorps monoclonaux anti-galectine-9 en vue d'applications diagnostiques et thérapeutiques

  2013cites this paper
• Caractérisation de la mort cellulaire induite par un anticorps trifonctionnel

  2013cites this paper
• Targeting ER stress induced apoptosis and inflammation in cancer.

  2013cites this paper
• Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer.

  2013cites this paper
• Antitumor Virotherapy by Attenuated Measles Virus (MV)

  2013cites this paper
• Harnessing the Potential of Radiation-Induced Immune Modulation for Cancer Therapy

  2013cites this paper
• Immunogenic tumor cell death induced by chemoradiotherapy: molecular mechanisms and a clinical translation

  2013cites this paper
• TNFR-1 on tumor cells contributes to the sensitivity of fibrosarcoma to chemotherapy

  2013cites this paper
• Dendritic Cells for Cancer Immunotherapy

  2013cites this paper
• Use of anti-cancer drugs, mitocans, to enhance the immune responses against tumors.

  2013cites this paper
• The novel cancer-testis antigen A-kinase anchor protein 4 (AKAP4) is a potential target for immunotherapy of ovarian serous carcinoma

  2013influential citation
• The secret ally: immunostimulation by anticancer drugs

  2012cites this paper
• Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity

  2012influential citation
• Células dendríticas II, utilización clínica en vacunación antitumoral

  2012cites this paper
• TLR/MyD88 signaling in B cells suppresses T cell-mediated CNS autoimmunity

  2012cites this paper
• ER stress-induced inflammation: does it aid or impede disease progression?

  2012cites this paper
• Contribution of ER Stress to Immunogenic Cancer Cell Death

  2012cites this paper
• Cell death programs in Yersinia immunity and pathogenesis

  2012cites this paper
• Oncogenic BRAF(V600E) Promotes Stromal Cell-Mediated Immunosuppression Via Induction of Interleukin-1 in Melanoma

  2012cites this paper
• BRAF(V600) Inhibitor GSK2118436 Targeted Inhibition of Mutant BRAF in Cancer Patients Does Not Impair Overall Immune Competency

  2012cites this paper
• A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

  2012cites this paper
• The interactions of therapeutic antibodies with Fc receptors.

  2012cites this paper
• Immunogenic tumor cell death induced by chemoradiotherapy in patients with esophageal squamous cell carcinoma.

  2012cites this paper
• Radiation combined with hyperthermia induces HSP70-dependent maturation of dendritic cells and release of pro-inflammatory cytokines by dendritic cells and macrophages.

  2011cites this paper
• Oncosuppressive Functions of Autophagy

  2011cites this paper
• ROLES FOR BRAF KINASE ACTIVATING MUTATIONS IN MELANOMA: MICROENVIRONMENTAL IMMUNOSUPPRESSION

  2011cites this paper
• Cell death in the neighbourhood: direct microenvironmental effects of apoptosis in normal and neoplastic tissues

  2011cites this paper
• Nitric oxide: role in tumour biology and iNOS/NO-based anticancer therapies

  2011cites this paper
• Integration of host-related signatures with cancer cell-derived predictors for the optimal management of anticancer chemotherapy.

  2010cites this paper
• The Polypeptide Binding Conformation of Calreticulin Facilitates Its Cell-surface Expression under Conditions of Endoplasmic Reticulum Stress*

  2010cites this paper