Transition Metal-Free 1,2-Carboboration of Unactivated Alkenes

A method for transition metal-free 1,2-carboboration of unactivated alkenes with bis(catecholato)diboron as the boron source in combination with alkyl halides as the alkyl component is introduced. The three-component reaction proceeds via a radical pathway on a broad range of unactivated alkenes, and the 1,2-carboboration products serve as valuable synthetic building blocks. Density functional theory calculations provide insights into the mechanism.

• Publication year

  2018

• Venue

  Journal of the American Chemical Society

• Publication date

  2018-05-09

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/jacs.8b03333PMID 29741375PMCID 6014685
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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