Dopamine neuron glutamate cotransmission: frequency-dependent modulation in the mesoventromedial projection.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Neuroscience

• Publication date

  2009-12-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.neuroscience.2009.08.057PMID 19729052PMCID PMC2783216
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Dopamine Signaling Differences in the Nucleus Accumbens and Dorsal Striatum Exploited by Nicotine

  2009cited by this paper
• Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli

  2009cited by this paper
• Controls of Tonic and Phasic Dopamine Transmission in the Dorsal and Ventral Striatum

  2009cited by this paper
• Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

  2009cited by this paper
• Two types of dopamine neuron distinctly convey positive and negative motivational signals

  2009cited by this paper
• Developmental and Target-Dependent Regulation of Vesicular Glutamate Transporter Expression by Dopamine Neurons

  2008cited by this paper
• Individual dopamine midbrain neurons: functional diversity and flexibility in health and disease.

  2008cited by this paper
• The vesicular glutamate transporter VGLUT3 synergizes striatal acetylcholine tone

  2008cited by this paper
• Opposing Patterns of Signaling Activation in Dopamine D1 and D2 Receptor-Expressing Striatal Neurons in Response to Cocaine and Haloperidol

  2008cited by this paper
• Recurrent Collateral Connections of Striatal Medium Spiny Neurons Are Disrupted in Models of Parkinson's Disease

  2008cited by this paper
• Midbrain Dopamine Neurons: Projection Target Determines Action Potential Duration and Dopamine D2 Receptor Inhibition

  2008cited by this paper
• Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors.

  2008cited by this paper
• Co-transmission of dopamine and GABA in periglomerular cells.

  2008cited by this paper
• D2 dopamine modulation of corticoaccumbens synaptic responses changes during adolescence

  2008cited by this paper
• Glutamate in dopamine neurons: synaptic versus diffuse transmission.

  2008cited by this paper
• Drd1a-tdTomato BAC Transgenic Mice for Simultaneous Visualization of Medium Spiny Neurons in the Direct and Indirect Pathways of the Basal Ganglia

  2008cited by this paper
• Chemical transmission between dopaminergic neuron pairs

  2008cited by this paper
• Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system.

  2008cited by this paper
• Glutamate receptors on dopamine neurons control the persistence of cocaine seeking.

  2008cited by this paper
• Presynaptic regulation of dendrodendritic dopamine transmission

  2007cited by this paper
• Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits

  2007cited by this paper
• Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.

  2007cited by this paper
• Altered expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in Parkinson disease.

  2007cited by this paper
• Topographical organization of GABAergic neurons within the ventral tegmental area of the rat

  2007cited by this paper
• Cocaine-Conditioned Place Preference by Dopamine-Deficient Mice Is Mediated by Serotonin

  2007cited by this paper
• Glutamatergic neurons are present in the rat ventral tegmental area

  2007cited by this paper
• The ability of the mesocortical dopamine system to operate in distinct temporal modes

  2007cited by this paper
• The debate over dopamine’s role in reward: the case for incentive salience

  2007cited by this paper
• Expression of the vesicular glutamate transporter vGluT2 in a subset of cones of the mouse retina

  2006cited by this paper
• Allosteric changes of the NMDA receptor trap diffusible dopamine 1 receptors in spines.

  2006cited by this paper
• Particular subpopulations of midbrain and hypothalamic dopamine neurons express vesicular glutamate transporter 2 in the rat brain

  2006cited by this paper
• Expression of vesicular glutamate transporter-2 in gonadotrope and thyrotrope cells of the rat pituitary. Regulation by estrogen and thyroid hormone status.

  2006cited by this paper
• Dopamine D(2) receptor modulation of K(+) channel activity regulates excitability of nucleus accumbens neurons at different membrane potentials.

  2006cited by this paper
• The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons?

  2006cited by this paper
• Neural systems of reinforcement for drug addiction: from actions to habits to compulsion

  2005cited by this paper
• Targeted gene expression in dopamine and serotonin neurons of the mouse brain.

  2005cited by this paper
• Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection.

  2005cited by this paper
• Molecular and Cellular Diversity of Neuronal G-Protein-Gated Potassium Channels

  2005cited by this paper
• Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior

  2005cited by this paper
• Mesocortical Dopamine Neurons Operate in Distinct Temporal Domains Using Multimodal Signaling

  2005cited by this paper
• Vglut2 afferents to the medial prefrontal and primary somatosensory cortices: A combined retrograde tracing in situ hybridization

  2005cited by this paper
• Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons.

  2004cited by this paper
• Dopamine Neurons Mediate a Fast Excitatory Signal via Their Glutamatergic Synapses

  2004influential reference
• Real‐time decoding of dopamine concentration changes in the caudate–putamen during tonic and phasic firing

  2004cited by this paper
• Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals.

  2004cited by this paper
• Systematic presence of GABA-immunoreactivity in the tubero-infundibular and tubero-hypophyseal dopaminergic axonal systems: an ultrastructural immunogold study on several mammals

  2004cited by this paper
• Dopamine neurons in culture express VGLUT2 explaining their capacity to release glutamate at synapses in addition to dopamine

  2004cited by this paper
• Frequency-dependent modulation of dopamine release by nicotine

  2004cited by this paper
• Dopaminergic Modulation of Prefrontal Cortical Input to Nucleus Accumbens Neurons In Vivo

  2004cited by this paper
• Functional diversity of ventral midbrain dopamine and GABAergic neurons

  2004cited by this paper
• DAncing past the DAT at a DA synapse.

  2004cited by this paper
• Cooperative activation of dopamine D1 and D2 receptors increases spike firing of nucleus accumbens neurons via G-protein betagamma subunits.

  2003cited by this paper
• Real‐time decoding of dopamine concentration changes in the caudate–putamen during tonic and phasic firing

  2003cited by this paper
• Presynaptic regulation of dopaminergic neurotransmission

  2003cited by this paper
• Dopaminergic Modulation of Axon Collaterals Interconnecting Spiny Neurons of the Rat Striatum

  2003cited by this paper
• Cooperative Activation of Dopamine D1 and D2 Receptors Increases Spike Firing of Nucleus Accumbens Neurons via G-Protein βγ Subunits

  2003cited by this paper
• Altered Dopamine Release and Uptake Kinetics in Mice Lacking D2 Receptors

  2002cited by this paper
• Time window of autoreceptor‐mediated inhibition of limbic and striatal dopamine release

  2002cited by this paper
• Inhibition of Dopamine Release Via Presynaptic D2 Receptors: Time Course and Functional Characteristics In Vivo

  2001cited by this paper
• Ionic channels of excitable membranes

  2001cited by this paper
• Differential Expression of the Small-Conductance, Calcium-Activated Potassium Channel SK3 Is Critical for Pacemaker Control in Dopaminergic Midbrain Neurons

  2001cited by this paper
• Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

  2001cited by this paper
• The adolescent brain and age-related behavioral manifestations.

  2000cited by this paper
• Mesoaccumbens dopamine neuron synapses reconstructed in vitro are glutamatergic.

  2000cited by this paper
• Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons

  2000cited by this paper
• Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens.

  2000cited by this paper
• Unveiling synaptic plasticity: a new graphical and analytical approach.

  2000cited by this paper
• Striatonigrostriatal Pathways in Primates Form an Ascending Spiral from the Shell to the Dorsolateral Striatum

  2000cited by this paper
• Postmortem elevation in extracellular glutamate in the rat hippocampus when brain temperature is maintained at physiological levels: implications for the use of human brain autopsy tissues.

  1999cited by this paper
• Dopamine Neurons Make Glutamatergic Synapses In Vitro

  1998cited by this paper
• A subset of ventral tegmental area neurons is inhibited by dopamine, 5-hydroxytryptamine and opioids.

  1997cited by this paper
• Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area.

  1992cited by this paper
• Membrane properties and synaptic responses of rat striatal neurones in vitro.

  1991cited by this paper
• Evidence for coexistence of GABA and dopamine in neurons of the rat olfactory bulb

  1987cited by this paper

• VGLUT2 in Parkinson’s disease: an emerging therapeutic target

  2026cites this paper
• Aging disrupts the coordination between mRNA and protein expression in mouse and human midbrain

  2025cites this paper
• Dopamine-Glutamate and Dopamine-GABA Co-release.

  2025cites this paper
• GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABAA receptors

  2024cites this paper
• Aging disrupts the coordination between mRNA and protein expression in mouse and human midbrain

  2024cites this paper
• Investigation of neural functional connectivity in thick acute mouse brain slices with novel multi-region 3D neural probe arrays

  2024cites this paper
• A mini-review of the role of vesicular glutamate transporters in Parkinson’s disease

  2023cites this paper
• Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration

  2023cites this paper
• CRISPR/Cas9-based QF2 knock-in at the tyrosine hydroxylase (th) locus reveals novel th-expressing neuron populations in the zebrafish mid- and hindbrain

  2023cites this paper
• Relevance of interactions between dopamine and glutamate neurotransmission in schizophrenia

  2022cites this paper
• Sodium hydrogen sulfide upregulates cystathionine β-synthase and protects striatum against 3-nitropropionic acid-induced neurotoxicity in rats.

  2021cites this paper
• Deletion of VGLUT2 in Midbrain Dopamine Neurons Attenuates Dopamine and Glutamate Responses to Methamphetamine in Mice.

  2021cites this paper
• Glutamic Acid Transporters: Targets for Neuroprotective Therapies in Parkinson’s Disease

  2021cites this paper
• Dopamine Neurons That Cotransmit Glutamate, From Synapses to Circuits to Behavior

  2021cites this paper
• Vesicular glutamate transporter modulates sex differences in dopamine neuron vulnerability to age‐related neurodegeneration

  2021cites this paper
• Roles of dopamine and glutamate co‐release in the nucleus accumbens in mediating the actions of drugs of abuse

  2020cites this paper
• VTA Glutamate Neuron Activity Drives Positive Reinforcement Absent Dopamine Co-release.

  2020cites this paper
• Developments from Bulk Optogenetics to Single-Cell Strategies to Dissect the Neural Circuits that Underlie Aberrant Motivational States.

  2020cites this paper
• Pharmacology of GABA and Its Receptors

  2020cites this paper
• Glutamate homeostasis and dopamine signaling: implications for psychostimulant addiction behavior.

  2020cites this paper
• Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner

  2020cites this paper
• Opposing Ventral Striatal Medium Spiny Neuron Activities Shaped by Striatal Parvalbumin-Expressing Interneurons during Goal-Directed Behaviors.

  2020cites this paper
• Anatomical and computational models of the role of phasic dopamine signaling in intracranial self-stimulation: psychophysical and electrochemical tests

  2019cites this paper
• Imaging Neuronal Pathways of the Rat Basal Ganglia System with 52Mn PET and MEMRI

  2019cites this paper
• The role of co-neurotransmitters in sleep and wake regulation

  2018cites this paper
• Modulation des Kontrollnetzwerkes für Nahrungsaufnahme: Eine kombinierte fMRT- und rTMS-Studie an gesunden Probanden

  2018cites this paper
• Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio

  2018cites this paper
• l-Carnosine as Adjunctive Therapy in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

  2018cites this paper
• Genetic deletion of vesicular glutamate transporter in dopamine neurons increases vulnerability to MPTP-induced neurotoxicity in mice

  2018cites this paper
• Fronto-Striatal Glutamate in TS and/or ADHD

  2017cites this paper
• Amphetamine and Methamphetamine Increase NMDAR-GluN2B Synaptic Currents in Midbrain Dopamine Neurons

  2017cites this paper
• Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT.

  2017cites this paper
• Structual and neurochemical correlates of Tourette’s disorder and attention-deficit hyperactivity disorder

  2017cites this paper
• The Effects of Dopamine on Frequency Dependent Short Term Synaptic Plasticity: A Comparison of Layer Contributions and Rhythmic Dynamics

  2017cites this paper
• Subtype‐specific effects of dopaminergic D2 receptor activation on synaptic trains in layer V pyramidal neurons in the mouse prefrontal cortex

  2017cites this paper
• Regulation of System Xc-by the Neuropeptide PACAP: Implications for Glutamate Transmission in Drug Addiction

  2017cites this paper
• Compulsivity and glutamate in neurodevelopment

  2017cites this paper
• Metabotropic Glutamate Receptors and Parkinson’s Disease: Basic and Preclinical Neuroscience

  2017cites this paper
• Fronto-striatal glutamate in children with Tourette's disorder and attention-deficit/hyperactivity disorder☆

  2016cites this paper
• Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain

  2016cites this paper
• Ventral Tegmental Area Afferents and Drug-Dependent Behaviors

  2016cites this paper
• Multiplexed neurochemical signaling by neurons of the ventral tegmental area.

  2016cites this paper
• Title The ever-changing brain : Clinical implications Introduction Permalink

  2016cites this paper
• Limbic-Basal Ganglia Circuits Parallel and Integrative Aspects

  2016cites this paper
• The neural substrates for the rewarding and dopamine-releasing effects of medial forebrain bundle stimulation have partially discrepant frequency responses.

  2016cites this paper
• Relating the midbrain dopaminergic system to hippocampal cell assembly dynamics associated with spatial memory function

  2015cites this paper
• Attenuation Of Methamphetamine And Nmda-Induced Toxicity By Leptin In Murine Striatum

  2015cites this paper
• A 40-bp VNTR polymorphism in the 3′-untranslated region of DAT1/SLC6A3 is associated with ADHD but not with alcoholism

  2015cites this paper
• Co-localization of Gamma-Aminobutyric Acid and Glutamate in Neurons of the Spider Central Nervous System

  2015cites this paper
• GLAST But Not Least—Distribution, Function, Genetics and Epigenetics of l-Glutamate Transport in Brain—Focus on GLAST/EAAT1

  2015cites this paper
• Brainstem system of hippocampal theta induction: The role of the ventral tegmental area

  2015cites this paper
• Neuromodulation of spinal networks in embryonic and larval zebrafish

  2015cites this paper
• vglut2 and gad expression reveal distinct patterns of dual GABAergic versus glutamatergic cotransmitter phenotypes of dopaminergic and noradrenergic neurons in the zebrafish brain

  2014influential citation
• GABAergic and glutamatergic efferents of the mouse ventral tegmental area

  2014cites this paper
• Quantitative Multi-modal Brain Autoradiography of Glutamatergic, Dopaminergic, Cannabinoid, and Nicotinic Receptors in Mutant Disrupted-In-Schizophrenia-1 (DISC1) Mice

  2014cites this paper
• An update on the connections of the ventral mesencephalic dopaminergic complex.

  2014cites this paper
• Delineating midbrain circuits underlying motivated behaviors

  2014cites this paper
• Dual-transmitter neurons: functional implications of co-release and co-transmission.

  2014cites this paper
• Reward and aversion in a heterogeneous midbrain dopamine system.

  2014cites this paper
• Local control of striatal dopamine release

  2014cites this paper
• Glutamate neurons within the midbrain dopamine regions.

  2014influential citation
• Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system.

  2013cites this paper
• Levodopa–induced dyskinesias in the absence of nigrostriatal degeneration

  2013cites this paper
• Olfactory Bulb Short Axon Cell Release of GABA and Dopamine Produces a Temporally Biphasic Inhibition–Excitation Response in External Tufted Cells

  2013cites this paper
• Improved techniques for examining rapid dopamine signaling with iontophoresis.

  2013cites this paper
• Quantitative unit classification of ventral tegmental area neurons in vivo.

  2012cites this paper
• Optogenetic strategies to dissect the neural circuits that underlie reward and addiction.

  2012cites this paper
• Induction of hippocampal theta rhythm by electrical stimulation of the ventral tegmental area and its loss after septum inactivation.

  2012cites this paper
• The dopaminergic innervation of the macaque prefrontal cortex

  2012cites this paper
• Dopamine's role in risk taking: a specific look at dopamine deficiency and gambling

  2012cites this paper
• Insights to drug addiction derived from ultrastructural views of the mesocorticolimbic system

  2012cites this paper
• Properties of dopaminergic neurons in organotypic mesencephalic–striatal co‐cultures – evidence for a facilitatory effect of dopamine on the glutamatergic input mediated by α‐1 adrenergic receptors

  2011influential citation
• Mizumori spatial learning Ventral tegmental area and substantia nigra neural correlates of

  2011cites this paper
• Dopaminergic axons in different divisions of the adult rat striatal complex do not express vesicular glutamate transporters

  2011cites this paper
• Mesocorticolimbic Glutamatergic Pathway

  2011cites this paper
• Glutamatergic signaling by midbrain dopaminergic neurons: recent insights from optogenetic, molecular and behavioral studies.

  2011cites this paper
• Functional Mapping of the Neural Circuitry of Rat Maternal Motivation: Effects of Site‐Specific Transient Neural Inactivation

  2011cites this paper
• Ventral tegmental area and substantia nigra neural correlates of spatial learning.

  2011cites this paper
• Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate

  2010cites this paper
• Expression of NMDA receptor subunits in human peripheral blood lymphocytes in opioid addiction.

  2010cites this paper
• Glutamatergic Signaling by Mesolimbic Dopamine Neurons in the Nucleus Accumbens

  2010influential citation
• Development of an Embryonic Stem Cell-Based Therapy for Replacement of Spiral Ganglion Neurons.

  2010cites this paper
• Electrophysiological evidence of mediolateral functional dichotomy in the rat nucleus accumbens during cocaine self‐administration II: phasic firing patterns

  2010cites this paper
• Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo.

  2010cites this paper
• Dopamine in motivational control: rewarding, aversive, and alerting.

  2010cites this paper
• In vitro identification and electrophysiological characterization of dopamine neurons in the ventral tegmental area.

  2010cites this paper
• Computational models of reinforcement learning: the role of dopamine as a reward signal

  2010cites this paper
• Electrophysiological evidence of mediolateral functional dichotomy in the rat accumbens during cocaine self‐administration: tonic firing patterns

  2009cites this paper
• Universidade Federal do Rio Grande do Sul Instituto de Ciências Básicas da Saúde Programa de Pós-Graduação em Ciências Biológicas: Bioquímica

  2008cites this paper
• List of papers

  1995cites this paper
• Optogenetic Strategies to Dissect the Neural Circuits That Underlie Reward and Addiction Opsins and Hardware to Control Specific Neuronal Pathways with Light Optogenetic Strategies

  year unknowncites this paper