GABAergic and glutamatergic efferents of the mouse ventral tegmental area

No abstract is available for this paper.

• Publication year

  2014

• Venue

  The Journal of comparative neurology

• Publication date

  2014-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/cne.23603PMID 24715505PMCID PMC4107038
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adenosine A2A receptor blockade reverts hippocampal stress-induced deficits and restores corticosterone circadian oscillation

  2013cited by this paper
• A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward.

  2013cited by this paper
• GABAergic neurons regulate lateral ventricular development via transcription factor Pax5

  2013cited by this paper
• Cocaine Disinhibits Dopamine Neurons by Potentiation of GABA Transmission in the Ventral Tegmental Area

  2013cited by this paper
• Activation of VTA GABA neurons disrupts reward consumption.

  2012cited by this paper
• Whole-brain mapping of direct inputs to midbrain dopamine neurons.

  2012cited by this paper
• Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning

  2012cited by this paper
• Characterization of axo‐axonic synapses in the piriform cortex of Mus musculus

  2012cited by this paper
• Ventral Tegmental Area Glutamate Neurons: Electrophysiological Properties and Projections

  2012influential reference
• GABA neurons of the VTA drive conditioned place aversion.

  2012influential reference
• The glutamatergic component of the mesocortical pathway emanating from different subregions of the ventral midbrain.

  2012cited by this paper
• Neuron-type specific signals for reward and punishment in the ventral tegmental area

  2011cited by this paper
• Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli.

  2011cited by this paper
• Negative Reward Signals from the Lateral Habenula to Dopamine Neurons Are Mediated by Rostromedial Tegmental Nucleus in Primates

  2011cited by this paper
• Mesocorticolimbic Glutamatergic Pathway

  2011influential reference
• Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons.

  2011cited by this paper
• Dopaminergic Terminals in the Nucleus Accumbens But Not the Dorsal Striatum Corelease Glutamate

  2010cited by this paper
• Brain reward circuitry beyond the mesolimbic dopamine system: a neurobiological theory.

  2010cited by this paper
• Glutamatergic Signaling by Mesolimbic Dopamine Neurons in the Nucleus Accumbens

  2010cited by this paper
• Neural bases for addictive properties of benzodiazepines

  2010cited by this paper
• Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo.

  2010cited by this paper
• Glutamatergic and Nonglutamatergic Neurons of the Ventral Tegmental Area Establish Local Synaptic Contacts with Dopaminergic and Nondopaminergic Neurons

  2010cited by this paper
• Dopamine neuron glutamate cotransmission: frequency-dependent modulation in the mesoventromedial projection.

  2009cited by this paper
• The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta

  2009influential reference
• Ultrastructural analysis of local collaterals of rat ventral tegmental area neurons: GABA phenotype and synapses onto dopamine and GABA cells

  2009cited by this paper
• Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system.

  2008cited by this paper
• Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

  2008cited by this paper
• Glutamatergic neurons are present in the rat ventral tegmental area

  2007cited by this paper
• Dopaminergic projections from the VTA substantially contribute to the mesohabenular pathway in the rat.

  2007cited by this paper
• Ventral tegmental area neurons in learned appetitive behavior and positive reinforcement.

  2007cited by this paper
• Efferent connections of the rostral linear nucleus of the ventral tegmental area in the rat.

  2007cited by this paper
• Topographical organization of GABAergic neurons within the ventral tegmental area of the rat

  2007cited by this paper
• Brain stimulation reward is integrated by a network of electrically coupled GABA neurons.

  2007cited by this paper
• Particular subpopulations of midbrain and hypothalamic dopamine neurons express vesicular glutamate transporter 2 in the rat brain

  2006cited by this paper
• Afferents of the ventral tegmental area in the rat‐anatomical substratum for integrative functions

  2005cited by this paper
• Vglut2 afferents to the medial prefrontal and primary somatosensory cortices: A combined retrograde tracing in situ hybridization

  2005cited by this paper
• Mesocortical Dopamine Neurons Operate in Distinct Temporal Domains Using Multimodal Signaling

  2005cited by this paper
• GABAergic projection from the ventral tegmental area and substantia nigra to the periaqueductal gray region and the dorsal raphe nucleus

  2004cited by this paper
• Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67‐GFP knock‐in mouse

  2003cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area

  2003cited by this paper
• Cellular and synaptic mechanisms of nicotine addiction.

  2002cited by this paper
• Lesions of the Tegmental Pedunculopontine Nucleus Block the Rewarding Effects and Reveal the Aversive Effects of Nicotine in the Ventral Tegmental Area

  2002cited by this paper
• Mu and kappa opioid agonists modulate ventral tegmental area input to the ventral pallidum

  2002cited by this paper
• SHORT COMMUNICATION Inhibition of GABAergic neurotransmission in the ventral tegmental area by cannabinoids

  2002cited by this paper
• Molecular and Physiological Diversity of Nicotinic Acetylcholine Receptors in the Midbrain Dopaminergic Nuclei

  2001cited by this paper
• Projections from the Rat Prefrontal Cortex to the Ventral Tegmental Area: Target Specificity in the Synaptic Associations with Mesoaccumbens and Mesocortical Neurons

  2000cited by this paper
• GABA‐containing neurons in the rat ventral tegmental area project to the prefrontal cortex

  2000cited by this paper
• Role and Origin of the GABAergic Innervation of Dorsal Raphe Serotonergic Neurons

  2000cited by this paper
• Regional expression of a gene encoding a neuron-specific Na(+)-dependent inorganic phosphate cotransporter (DNPI) in the rat forebrain.

  2000cited by this paper
• Localization of brain reinforcement mechanisms: intracranial self-administration and intracranial place-conditioning studies.

  1999cited by this paper
• Electrophysiological Characterization of GABAergic Neurons in the Ventral Tegmental Area

  1998cited by this paper
• Addictive drugs and brain stimulation reward.

  1996cited by this paper
• GABA-containing neurons in the ventral tegmental area project to the nucleus accumbens in rat brain.

  1995influential reference
• The sites of origin of dopaminergic afferent fibers to the lateral habenular nucleus in the rat

  1993cited by this paper
• Comparative localization of mRNAs encoding two forms of glutamic acid decarboxylase with nonradioactive in situ hybridization methods

  1993cited by this paper
• Inhibitory effects of ventral tegmental area stimulation on the activity of prefrontal cortical neurons: evidence for the involvement of both dopaminergic and GABAergic components.

  1992cited by this paper
• Topography and functional role of dopaminergic projections from the ventral mesencephalic tegmentum to the ventral pallidum.

  1992cited by this paper
• Opioids excite dopamine neurons by hyperpolarization of local interneurons

  1992cited by this paper
• Anatomical substrates of cholinergic‐autonomic regulation in the rat

  1990cited by this paper
• Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

  1988cited by this paper
• The projections of the ventral tegmental area and adjacent regions: a combined fluorescent retrograde tracer and immunofluorescence study in the rat.

  1982influential reference

• Stress resilience is associated with transcriptional remodeling in the VTA.

  2026cites this paper
• VTA-forebrain connectivity moderates adaptive behavior

  2026cites this paper
• Pharmacological recruitment of a VTA glutamatergic arousal circuit by the natural product BN3 drives broad-spectrum emergence from general anesthesia

  2026cites this paper
• A VTA-pontine GABA pathway biases backward locomotion via local and distal inhibition

  2026cites this paper
• An endogenous GLP-1 circuit engages VTA GABA neurons to regulate mesolimbic dopamine neurons and attenuate cocaine seeking

  2025cites this paper
• Translating stress systems: corticotropin releasing factor, its receptors, and the dopamine system in nonhuman primate models

  2025cites this paper
• Ventral tegmental area interneurons revisited: GABA and glutamate projection neurons make local synapses

  2025cites this paper
• Social stress increases anxiety by GluA1-dependent synaptic strengthening of ventral tegmental area inputs to the basolateral amygdala.

  2025cites this paper
• Ventral Tegmental Area Glutamatergic Neurons Suppress Hippocampal Sharp-wave Ripples and Induce Head Movements in Mice

  2025cites this paper
• Projection-defined ventral tegmental area neurons exhibit fentanyl-induced molecular and functional adaptations that differentially support drug-context associations

  2025cites this paper
• Superior Colliculus Projections Drive Dopamine Neuron Activity and Movement But Not Value

  2025cites this paper
• Chronic Fluoxetine Treatment Desensitizes Serotoninergic Inhibition of GABAergic Inputs and Intrinsic Excitability of Dorsal Raphe Serotonin Neurons

  2025cites this paper
• Stress resilience is associated with transcriptional remodeling in the VTA

  2025cites this paper
• Superior colliculus projections drive dopamine neuron activity and movement but not value

  2025cites this paper
• Cocaine and Morphine Converge to Disrupt Chloride Homeostasis in Ventral Tegmental Area GABA Neurons

  2025cites this paper
• Ventral tegmental area GABA neurons integrate positive and negative valence

  2025cites this paper
• Ventral tegmental area GABA neurons integrate positive and negative valence

  2024cites this paper
• Chronic fluoxetine treatment desensitizes serotoninergic inhibition of GABA inputs and the intrinsic excitability of dorsal raphe serotonin neurons

  2024cites this paper
• Midbrain glutamatergic circuit mechanism of resilience to socially transferred allodynia in male mice

  2024cites this paper
• Refining the circuits of drug addiction: The ventral pallidum.

  2024cites this paper
• The role of the GABAergic cells of the median raphe region in reinforcement-based learning

  2024cites this paper
• Connexin‐36‐positive gap junctions in ventral tegmental area GABA neurons sustain opiate dependence

  2024cites this paper
• Phasic dopamine signals are reduced in the spontaneously hypertensive rat and increased by methylphenidate

  2024cites this paper
• An endogenous GLP-1 circuit engages VTA GABA neurons to regulate mesolimbic dopamine neurons and attenuate cocaine seeking

  2024cites this paper
• Stress-induced anxiety-related behavior in mice is driven by enhanced excitability of ventral tegmental area GABA neurons

  2024influential citation
• Ventral tegmental area interneurons revisited: GABA and glutamate projection neurons make local synapses

  2024cites this paper
• Targeting the ventral pallidum in obesity

  2024cites this paper
• Midbrain KCC2 downregulation: Implications for stress-related and substance use behaviors.

  2024cites this paper
• GABAergic modulation of sleep-wake states.

  2023cites this paper
• Differential role of GABAergic and cholinergic ventral pallidal neurons in behavioral despair, conditioned fear memory and active coping.

  2023cites this paper
• A novel hypothalamic-midbrain circuit for model-based learning

  2023cites this paper
• Rewarding-unrewarding prediction signals under a bivalent context in the primate lateral hypothalamus

  2023cites this paper
• Atypical antipsychotics antagonize GABA_A receptors in the ventral tegmental area GABA neurons to relieve psychotic behaviors

  2023cites this paper
• Ventral tegmental area glutamate neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate opioid-seeking behavior

  2023cites this paper
• Ventral pallidal regulation of motivated behaviors and reinforcement

  2023cites this paper
• Effect of Deep Brain Stimulation in The Ventral Tegmental Area on Neuronal Activity in Local and Remote Brain Regions in Kindled Mice

  2023cites this paper
• Nicotine addiction: More than just dopamine.

  2023cites this paper
• epithalamic lateral habenula promotes rewarding behaviours independently

  2023cites this paper
• A preclinical study of deep brain stimulation in the ventral tegmental area for alleviating positive psychotic-like behaviors in mice

  2022cites this paper
• α2δ‐1 protein drives opioid‐induced conditioned reward and synaptic NMDA receptor hyperactivity in the nucleus accumbens

  2022influential citation
• Pharmacological modulation of ventral tegmental area neurons elicits changes in trigeminovascular sensory processing and is accompanied by glycemic changes: Implications for migraine

  2022cites this paper
• ACh signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms

  2022cites this paper
• Unbiased stereological estimates of dopaminergic and GABAergic neurons in the A10, A9, and A8 subregions in the young male Macaque

  2022cites this paper
• Anatomy and Function of Ventral Tegmental Area Glutamate Neurons

  2022cites this paper
• Differential Role of GABAergic and Cholinergic Ventral Pallidal Neurons in Behavioral Despair, Conditioned Fear Memory and Active Coping

  2022influential citation
• Control of Behavioral Arousal and Defense by a Glutamatergic Midbrain-Amygdala Pathway in Mice

  2022cites this paper
• Ventral Tegmental Area Glutamate Neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate prescription opioid-seeking behavior

  2022cites this paper
• Median raphe serotonergic neurons projecting to the interpeduncular nucleus control preference and aversion

  2022cites this paper
• Cav1.3 L-type Ca2+ channel-activated CaMKII/ERK2 pathway in the ventral tegmental area is required for cocaine conditioned place preference.

  2022cites this paper
• Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear

  2022cites this paper
• Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward

  2022influential citation
• Neural circuits provide insights into reward and aversion

  2022cites this paper
• Characterizing and TRAPing a Social Stress-Activated Neuronal Ensemble in the Ventral Tegmental Area

  2022cites this paper
• Mesoaccumbal glutamate neurons drive reward via glutamate release, but aversion via dopamine co-release

  2022cites this paper
• GABAB Receptors and Drug Addiction: Psychostimulants and Other Drugs of Abuse.

  2021cites this paper
• Genetic Probe for Visualizing Glutamatergic Synapses and Vesicles by 3D Electron Microscopy

  2021cites this paper
• Oxytocin and Addiction: Potential Glutamatergic Mechanisms

  2021cites this paper
• O-GlcNAcylation in Ventral Tegmental Area Dopaminergic Neurons Regulates Motor Learning and the Response to Natural Reward

  2021cites this paper
• Dopaminergic Regulation of Serotonergic Dorsal Raphe Neurons: Role in the Control of Wakefulness and REM Sleep

  2021cites this paper
• Systemic oxytocin increases glutamate efflux in the nucleus accumbens core of cocaine-experienced male and female rats but only increases dopamine efflux in males.

  2021cites this paper
• The circadian clock in the mouse habenula is set by catecholamines

  2021influential citation
• Diverse midbrain dopaminergic neuron subtypes and implications for complex clinical symptoms of Parkinson’s disease

  2021cites this paper
• Ventral pallidum cellular and pathway specificity in drug seeking.

  2021cites this paper
• HCN2 in cholinergic interneurons of the nucleus accumbens mediates reward response

  2021cites this paper
• Dopamine Cell Therapy: From Cell Replacement to Circuitry Repair

  2021cites this paper
• Central Nervous System Associated With Light Perception and Physiological Responses of Birds

  2021cites this paper
• Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking.

  2021cites this paper
• Genetically Targeted Connectivity Tracing Excludes Dopaminergic Inputs to the Interpeduncular Nucleus from the Ventral Tegmentum and Substantia Nigra

  2021cites this paper
• Mapping the subcortical connectivity of the human default mode network

  2021influential citation
• Molecular, Circuit, and Stress Response Characterization of Ventral Pallidum Npas1-Neurons

  2021cites this paper
• A Whole-Brain Connectivity Map of VTA and SNc Glutamatergic and GABAergic Neurons in Mice

  2021cites this paper
• Central amygdala circuits in valence and salience processing.

  2021cites this paper
• Top-down projections of the prefrontal cortex to the ventral tegmental area, laterodorsal tegmental nucleus, and median raphe nucleus

  2021cites this paper
• Dopamine Neurons That Cotransmit Glutamate, From Synapses to Circuits to Behavior

  2021cites this paper
• Activation of LH GABAergic inputs counteracts fasting-induced changes in tVTA/RMTG neurons

  2021cites this paper
• Incentive motivation: 'wanting' roles of central amygdala circuitry.

  2021cites this paper
• Acetaldehyde Excitation of Lateral Habenular Neurons via Multiple Cellular Mechanisms

  2021cites this paper
• From Benzodiazepine Prescription to Dependence: Learning Processes Involved

  2021cites this paper
• Neural Substrates for the Regulation of Sleep and General Anesthesia

  2021cites this paper
• A mutant vesicular stomatitis virus with reduced cytotoxicity and enhanced anterograde trans-synaptic efficiency

  2020cites this paper
• NSS_A_278026 1215..1223

  2020cites this paper
• The Rostromedial Tegmental Nucleus: Anatomical Studies and Roles in Sleep and Substance Addictions in Rats and Mice

  2020cites this paper
• Chemogenetic activation of mesoaccumbal Gamma-Aminobutyric Acid projections selectively tunes responses to predictive cues when reward value is abruptly decreased

  2020influential citation
• Excitatory VTA to DH projections provide a valence signal to memory circuits

  2020cites this paper
• Investigating the Role of Phox2B-expressing Glutamatergic Parafacial Zone Neurons in Sleep Wake Control

  2020cites this paper
• Connexin-36-expressing Gap Junctions in VTA GABA Neurons Sustain Opiate Dependence

  2020cites this paper
• Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior

  2020cites this paper
• Activation of VTA GABA Neurons Disrupts Reward Seeking by Altering Temporal Processing

  2020cites this paper
• Whole‐brain efferent and afferent connectivity of mouse ventral tegmental area melanocortin‐3 receptor neurons

  2020influential citation
• A genetic probe for visualizing glutamatergic synapses and vesicles by 3D electron microscopy

  2020cites this paper
• Basal forebrain GABAergic neurons promote arousal and predatory hunting.

  2020cites this paper
• Ventral tegmental area GABAergic neurons induce anxiety-like behaviors and promote palatable food intake.

  2020cites this paper
• Neurochemical Signaling of Reward and Aversion to Ventral Tegmental Area Glutamate Neurons

  2020cites this paper
• Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area

  2020cites this paper
• Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective

  2020cites this paper
• Oxytocin treatment for alcoholism: Potential neurocircuitry targets.

  2020cites this paper
• Cerebellar Activation Bidirectionally Regulates Nucleus Accumbens Core and Medial Shell

  2020cites this paper
• Whole-brain opto-fMRI map of mouse VTA dopaminergic activation reflects structural projections with small but significant deviations

  2020cites this paper
• Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine D2R-mediated Sleep Reduction

  2020cites this paper
• A Whole-Brain Map and Assay Parameter Analysis of Mouse VTA Dopaminergic Activation

  2020cites this paper