Enhanced molecular typing of treponema pallidum: geographical distribution of strain types and association with neurosyphilis.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Infectious Diseases

• Publication date

  2010-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1086/656533PMID 20868271PMCID PMC3114648
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular epidemiology of syphilis in Scotland

  2009cited by this paper
• Macrolide treatment failure in a case of secondary syphilis: a novel A2059G mutation in the 23S rRNA gene of Treponema pallidum subsp. pallidum.

  2009cited by this paper
• Macrolide resistance and molecular types of Treponema pallidum causing primary syphilis in Shanghai, China.

  2009influential reference
• Evaluation of azithromycin resistance in Treponema pallidum specimens from Madagascar.

  2009cited by this paper
• Molecular Subtyping of Treponema pallidum subsp. pallidum in Lisbon, Portugal

  2009cited by this paper
• Molecular Typing of Treponema pallidum Clinical Strains from Lisbon, Portugal

  2008cited by this paper
• HIV and Syphilis: When to Perform a Lumbar Puncture

  2007cited by this paper
• Antibiotic selection may contribute to increases in macrolide-resistant Treponema pallidum.

  2006cited by this paper
• Detection of Treponema pallidum subsp. pallidum from Skin Lesions, Serum, and Cerebrospinal Fluid in an Infant with Congenital Syphilis after Clindamycin Treatment of the Mother during Pregnancy

  2006cited by this paper
• Azithromycin-resistant syphilis infection: San Francisco, California, 2000-2004.

  2006cited by this paper
• TprK Sequence Diversity Accumulates during Infection of Rabbits with Treponema pallidum subsp. pallidum Nichols Strain

  2006cited by this paper
• [Molecular detection and subtyping of Treponema pallidum subsp. pallidum in clinical specimens].

  2006cited by this paper
• Molecular typing of Treponema pallidum strains from patients with neurosyphilis in Pretoria, South Africa

  2006cited by this paper
• Molecular Subtyping of Treponema pallidum from North and South Carolina

  2005cited by this paper
• Treponema pallidum strain-specific differences in neuroinvasion and clinical phenotype in a rabbit model.

  2005cited by this paper
• Resurgence in Infectious Syphilis in Ireland: An Epidemiological Study

  2004cited by this paper
• Macrolide resistance in Treponema pallidum in the United States and Ireland.

  2004cited by this paper
• Cerebrospinal fluid abnormalities in patients with syphilis: association with clinical and laboratory features.

  2004cited by this paper
• Subfamily I Treponema pallidum repeat protein family: sequence variation and immunity.

  2004cited by this paper
• Molecular Typing of Treponema pallidum in South Africa: Cross-Sectional Studies

  2002cited by this paper
• Molecular subtyping of Treponema pallidum in an Arizona County with increasing syphilis morbidity: use of specimens from ulcers and blood.

  2001cited by this paper
• Multiple Alleles of Treponema pallidumRepeat Gene D in Treponema pallidum Isolates

  2000cited by this paper
• Molecular Subtyping of Treponema pallidum Subspecies pallidum

  1998influential reference

• Treponema pallidum’s neural invasion: from blood-brain barrier breach to immune sabotage

  2026cites this paper
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  2026cites this paper
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  2025cites this paper
• Reported Neurologic Manifestations Among Persons with Syphilis by Stage of Infection-12 States, 2019 -2022.

  2025cites this paper
• Neurosyphilis.

  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2024cites this paper
• Serofast status in syphilis: Pathogenesis to therapeutics.

  2024cites this paper
• Neurosyphilis: insights into its pathogenesis, susceptibility, diagnosis, treatment, and prevention

  2024cites this paper
• Clinical Insights: Antimicrobial Therapy for Infectious Uveitis

  2024cites this paper
• Treponema pallidum ssp pallidum, spirochète responsable de la syphilis

  2024cites this paper
• Analysis of molecular subtypes and antibiotic resistance in Treponema pallidum isolates from blood donors in Khyber Pakhtunkhwa, Pakistan

  2024cites this paper
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  2024cites this paper
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  2024cites this paper
• Molecular characterization of Treponema pallidum isolates from Brazil.

  2024cites this paper
• Decoding and Unravelling Mpox, Herpes, and Syphilis Infections: A State of Art Review.

  2024cites this paper
• Determination of molecular types and resistance to macrolides in Treponema pallidum isolates isolated in the Russian Federation in 2022.

  2024cites this paper
• A novel pan-proteome array for high-throughput profiling of the humoral response to Treponema pallidum

  2024cites this paper
• Development of methods for studying Treponema pallidum in the Russian Federation

  2024cites this paper
• Prospective evaluation of non-invasive saliva specimens for the diagnosis of syphilis and molecular surveillance of Treponema pallidum

  2024cites this paper
• Low genetic diversity of Treponema pallidum ssp. pertenue (TPE) isolated from patients’ ulcers in Namatanai District of Papua New Guinea: Local human population is infected by three TPE genotypes

  2024cites this paper
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  2023cites this paper
• Molecular Diagnostic Tools for Treponema pallidum

  2023cites this paper
• Molecular Detection and Typing of Treponema pallidum in Non-Ocular Samples from Patients with Ocular Syphilis

  2023cites this paper
• Syphilis: A Modern Resurgence.

  2023cites this paper
• A Cluster of Ocular Syphilis Cases with a Common Sex Partner — Southwest Michigan, 2022

  2023cites this paper
• CARE-NS, a research strategy for neurosyphilis

  2023cites this paper
• Whole genome sequence of a Treponema pallidum strain from a formalin-fixed paraffin-embedded fine needle aspirate of a cervical lymph node.

  2023cites this paper
• Recombinant Treponema pallidum protein Tp47 promoted the phagocytosis of macrophages by activating NLRP3 inflammasome induced by PKM2‐dependent glycolysis

  2023cites this paper
• Genomic epidemiology of syphilis in England: a population-based study

  2023cites this paper
• High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

  2022influential citation
• Treponema pallidum Subspecies Pallidum Intrapatient Homogeneity at Various Body Locations in Men with Infectious Syphilis

  2022cites this paper
• Reported Neurologic, Ocular, and Otic Manifestations Among Syphilis Cases—16 States, 2019

  2022cites this paper
• Characterisation of Treponema pallidum lineages within the contemporary syphilis outbreak in Australia: a genomic epidemiological analysis.

  2022cites this paper
• Prevalence of the A2058G mutation in 23S rRNA gene, which determines Treponema pallidum macrolide resistance in Russian population

  2022cites this paper
• High frequency of Nichols-like strains and increased levels of macrolide resistance in Treponema pallidum in clinical samples from Buenos Aires, Argentina

  2022cites this paper
• Investigating the role of whole genome sequencing in syphilis epidemiology: an English case study

  2022cites this paper
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  2022cites this paper
• Detection of Treponema pallidum DNA in Oropharyngeal Swabs and Whole Blood for Syphilis Diagnosis

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
• Endogenous Endophthalmitis: Etiology and Treatment

  2021cites this paper
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  2021cites this paper
• Treponema pallidum Macrolide Resistance and Molecular Epidemiology in Southern Africa, 2008 to 2018

  2021influential citation
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  2021cites this paper
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  2021cites this paper
• Neurosyphilis Presenting As Status Epilepticus, Successively Hemiparesis And Aphasia

  2021cites this paper
• Molecular Characterization Based on MLST and ECDC Typing Schemes and Antibiotic Resistance Analyses of Treponema pallidum subsp. pallidum in Xiamen, China

  2021influential citation
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  2021cites this paper
• Condyloma lata in secondary syphilis

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
• Pathogenic Spirochetes in Monkeys: Stealthy Pathogens of Global Importance

  2020cites this paper
• Treponema pallidum tprII subfamily genes internal fragments sequencing

  2020cites this paper
• Molecular typing of T. pallidum clinical isolates and their resistance to macrolides in the Russian Federation during 2018–2019

  2020cites this paper
• Neuroimaging Features, Follow-Up Analyses, and Comparisons Between Asymptomatic and Symptomatic Neurosyphilis

  2020cites this paper
• Tabes dorsal y meningitis sifilítica en paciente con virus de inmunodeficiencia humana

  2020cites this paper
• Molecular diagnostic of syphilis.

  2020cites this paper
• Otosyphilis: A Review of the Literature

  2020cites this paper
• Gene Expression Profiling in Human Brain Microvascular Endothelial Cells in Response to Treponema pallidum Subspecies pallidum.

  2020cites this paper
• Advancing the understanding of treponemal disease in the past and present.

  2020cites this paper
• Neurological Complications of Syphilis

  2020cites this paper
• The comparison of molecular typing in Treponema pallidum: Review and meta-analysis.

  2020cites this paper
• Epidemiology, molecular strain types, and macrolide resistance of Treponema pallidum in Japan, 2017-2018.

  2020cites this paper
• The Arg753Gln Polymorphism of Toll-Like Receptor 2 Has a Lower Occurrence in Patients with Syphilis, Suggesting Its Protective Effect in Czech and Slovak Individuals

  2020cites this paper
• Molecular and Direct Detection Tests for Treponema pallidum Subspecies pallidum: A Review of the Literature, 1964–2017

  2020cites this paper
• Treponema

  2020cites this paper
• A novel tp0548 Gene Type of Treponema pallidum identified in Nanjing, China: Case Report and Review of Literature.

  2020influential citation
• Molecular and Immunological Strategies Against Treponema pallidum Infections

  2020cites this paper
• Characterisation of the novel clinical isolate X-4 containing a new tp0548 sequence-type

  2020cites this paper
• The Modern Epidemic of Syphilis.

  2020cites this paper
• Investigation of syphilis immunology and Treponema pallidum subsp. pallidum biology to improve clinical management and design a broadly protective vaccine: study protocol

  2020cites this paper
• Sexually Transmitted Infections: Advances in Understanding and Management

  2020cites this paper
• Diagnosis of neurosyphilis: modern scientific and applied approaches (in Russian only)

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Enhanced molecular typing and macrolide and tetracycline-resistance mutations of Treponema pallidum in Barcelona.

  2019cites this paper
• Methods to improve short fragment NGS analysis - with a focus on ancient DNA

  2019cites this paper
• Molecular diversity of Treponema pallidum subspecies pallidum isolates in Amsterdam, the Netherlands

  2019cites this paper
• ВАРИАБЕЛЬНОСТЬ НУКЛЕОТИДНЫХ ПОСЛЕДОВАТЕЛЬНОСТЕЙ ГЕНА arp У РОССИЙСКИХ ИЗОЛЯТОВ TREPONEMA PALLIDUM

  2019cites this paper
• Treponema pallidum subsp. pallidum DNA and RNA in semen of a syphilis patient without genital or anal lesions. Possible implications for disease transmissibility.

  2019cites this paper
• Early syphilis: risk factors and clinical manifestations focusing on HIV-positive patients

  2019influential citation
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper