GPR103b functions in the peripheral regulation of adipogenesis.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Molecular Endocrinology

• Publication date

  2010-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/me.2010-0010PMID 20534693PMCID PMC5417454
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The orexigenic activity of the hypothalamic neuropeptide 26RFa is mediated by the neuropeptide Y and proopiomelanocortin neurons of the arcuate nucleus.

  2009cited by this paper
• Central administration of the RFamide peptides, QRFP-26 and QRFP-43, increases high fat food intake in rats.

  2008influential reference
• Analgesic effects of intrathecally administered 26RFa, an intrinsic agonist for GPR103, on formalin test and carrageenan test in rats.

  2008cited by this paper
• Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats.

  2008cited by this paper
• RFamide neuropeptides inhibit murine and human adipose differentiation.

  2008cited by this paper
• Neuropeptide Y is produced in visceral adipose tissue and promotes proliferation of adipocyte precursor cells via the Y1 receptor

  2008cited by this paper
• The role of RFamide peptides in feeding.

  2007cited by this paper
• Role of adipocyte-derived lipoprotein lipase in adipocyte hypertrophy

  2007cited by this paper
• P518/Qrfp sequence polymorphisms in SAMP6 osteopenic mouse.

  2007cited by this paper
• Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome

  2007cited by this paper
• 26RFa, a novel orexigenic neuropeptide, inhibits insulin secretion in the rat pancreas.

  2007cited by this paper
• Fatty acid transport protein 1 and long-chain acyl coenzyme A synthetase 1 interact in adipocytes Published, JLR Papers in Press, December 15, 2005.

  2006cited by this paper
• Recent advances in mammalian RFamide peptides: the discovery and functional analyses of PrRP, RFRPs and QRFP.

  2006cited by this paper
• A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice.

  2006influential reference
• The G-Protein-Coupled Receptor GPR103 Regulates Bone Formation

  2006influential reference
• Novel role of 26RFa, a hypothalamic RFamide orexigenic peptide, as putative regulator of the gonadotropic axis

  2006cited by this paper
• Optimized conditions for measuring lipolysis in murine primary adipocytes Published, JLR Papers in Press, May 4, 2006.

  2006cited by this paper
• RFamide peptide QRFP43 causes obesity with hyperphagia and reduced thermogenesis in mice.

  2006influential reference
• Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor.

  2004cited by this paper
• Ghrelin and des-acyl ghrelin both inhibit isoproterenol-induced lipolysis in rat adipocytes via a non-type 1a growth hormone secretagogue receptor.

  2004cited by this paper
• Transcription suppression of peroxisome proliferator-activated receptor gamma2 gene expression by tumor necrosis factor alpha via an inhibition of CCAAT/ enhancer-binding protein delta during the early stage of adipocyte differentiation.

  2004cited by this paper
• The expanding family of ‐RFamide peptides and their effects on feeding behaviour

  2004cited by this paper
• Transcription Suppression of Peroxisome Proliferator-Activated Receptor γ2 Gene Expression by Tumor Necrosis Factor α via an Inhibition of CCAAT/ Enhancer-binding Protein δ during the Early Stage of Adipocyte Differentiation

  2004cited by this paper
• Do regional differences in adipocyte biology provide new pathophysiological insights?

  2003cited by this paper
• Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity

  2003influential reference
• Identification and Characterization of a Novel RF-amide Peptide Ligand for Orphan G-protein-coupled Receptor SP9155*

  2003cited by this paper
• A New Peptidic Ligand and Its Receptor Regulating Adrenal Function in Rats*

  2003influential reference
• Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans.

  2003cited by this paper
• The role of ghrelin and growth hormone secretagogues receptor on rat adipogenesis.

  2003cited by this paper
• Neuropeptide AF and FF Modulation of Adipocyte Metabolism

  2002cited by this paper
• Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes.

  2002cited by this paper
• Lipoprotein lipase Published, JLR Papers in Press, October 1, 2002. DOI 10.1194/jlr.R200015-JLR200

  2002cited by this paper
• Lipoprotein lipase: the regulation of tissue specific expression and its role in lipid and energy metabolism

  2002cited by this paper
• Rodent obesity models: An overview

  2001cited by this paper
• Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats

  2001cited by this paper
• Discovery and mapping of ten novel G protein-coupled receptor genes.

  2001cited by this paper
• Adipocyte differentiation and gene expression.

  2000cited by this paper
• The release of lipoprotein lipase from 3T3-L1 adipocytes is regulated by microvessel endothelial cells in an insulin-dependent manner.

  2000cited by this paper
• Ghrelin induces adiposity in rodents

  2000cited by this paper
• Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm.

  1999cited by this paper
• Localization of adipocyte long-chain fatty acyl-CoA synthetase at the plasma membrane.

  1999cited by this paper
• Molecular regulation of adipocyte differentiation.

  1999cited by this paper
• Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats.

  1997cited by this paper
• Fatty acids regulate the expression of lipoprotein lipase gene and activity in preadipose and adipose cells.

  1996cited by this paper
• Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa)

  1993cited by this paper
• Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa).

  1992cited by this paper
• Neuropeptide Y and peptide YY inhibit lipolysis in human and dog fat cells through a pertussis toxin-sensitive G protein.

  1990influential reference
• Insulin regulation of lipoprotein lipase activity in 3T3-L1 adipocytes is mediated at posttranscriptional and posttranslational levels.

  1989cited by this paper
• Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats. 1985.

  1985cited by this paper
• Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats.

  1984cited by this paper
• Insulin regulation of lipoprotein lipase activity and release in 3T3-L1 adipocytes. Separation and dependence of hormonal effects on hexose metabolism and synthesis of RNA and protein.

  1979cited by this paper

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  2025cites this paper
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  2025cites this paper
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  2024influential citation
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  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2017cites this paper
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• regulates function and protects

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