Cytogenetics in multiple myeloma: a multicenter study of 24 patients with t(11;14)(q13;q32) or its variant.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Cancer Genetics and Cytogenetics

• Publication date

  1998-07-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0165-4608(97)00469-XPMID 9666807
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• International System for Human Cytogenetic Nomenclature

  2020cited by this paper
• 2 translocations, t(11;14) and t(1;6), in a patient with plasma cell leukaemia and 2 populations of plasma cells.

  2009cited by this paper
• The t(11;14) (q13;q32) in multiple myeloma cell line KMS12 has its 11q13 breakpoint 330 kb centromeric from the cyclin D1 gene.

  1997cited by this paper
• Non-random chromosomal rearrangements and their implications in clinical features and outcome of multiple myeloma and plasma cell leukemia.

  1996cited by this paper
• Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines.

  1996cited by this paper
• MULTIPLE MYELOMA: ALMOST ALL PATIENTS ARE CYTOGENETICALLY ABNORMAL

  1996cited by this paper
• Cytogenetic findings in 200 patients with multiple myeloma.

  1995cited by this paper
• The retinoblastoma gene (RB-1) status in multiple myeloma: a report on 35 cases.

  1995cited by this paper
• Overexpression of the PRAD1 oncogene in a patient with multiple myeloma and t(11;14)(q13;q32).

  1995cited by this paper
• Nonrandom karyotype abnormalities in 36 multiple myeloma patients.

  1995cited by this paper
• Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis.

  1995cited by this paper
• Molecular breakpoints of t(11;14)(q13;q32) in multiple myeloma.

  1995cited by this paper
• Cytogenetic study in multiple myeloma at diagnosis: comparison of two techniques

  1995cited by this paper
• Der(16)t(1;16)(q10;p10) in multiple myeloma: a new non-random abnormality that is frequently associated with Burkitt's-type translocations.

  1995cited by this paper
• Nonrandom chromosomal rearrangements of 14q32.3 and 19p13.3 and preferential deletion of 1p in 21 patients with multiple myeloma and plasma cell leukemia.

  1994cited by this paper
• Deletion of the retinoblastoma gene in multiple myeloma.

  1994cited by this paper
• Improved cytogenetic analysis of bone marrow plasma cells after cytokine stimulation in multiple myeloma: a report on 46 patients

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• Karyotype in multiple myeloma and plasma cell leukaemia.

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• Chromosome 11 translocation breakpoints at the PRAD1/cyclin D1 gene locus in centrocytic lymphoma.

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• Chromosome studies in plasma cell leukemia and multiple myeloma in transformation

  1992cited by this paper
• PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.

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• Translocation (11;14): A cytogenetic anomaly associated with B‐cell lymphomas of non‐follicle centre cell lineage

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• Ras oncogene mutation in multiple myeloma

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• Plasma cell karyotype in multiple myeloma.

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• Occurrence and type of chromosomal abnormalities in consecutive malignant monoclonal gammopathies: correlation with survival.

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• Plasma Cell Karyotype in Multiple Myeloma

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• Analysis of G banded karyotypes in myeloma cells.

  1986cited by this paper
• The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis.

  1985cited by this paper
• Non‐random chromosomal aberrations associated with multiple myeloma

  1984cited by this paper
• Translocation t(11;14) and trisomy 11q13----qter in multiple myeloma.

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• Cytogenetic study in multiple myeloma.

  1984cited by this paper
• Cytogenetic studies and clinical aspects of patients with plasma cell leukemia and leukemic macroglobulinemia.

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• Staging and kinetics of multiple myeloma.

  1982cited by this paper
• Karyotypic abnormalities and clinical aspects of patients with multiple myeloma and related paraproteinemic disorders

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• Future of Personalized Therapy Targeting Aberrant Signaling Pathways in Multiple Myeloma.

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• [The clinic and pathologic significance of plasma cell myeloma with CCND1].

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• immunoglobulin loci in multiple myeloma Cyclin D3 at 6p21 is dysregulated by recurrent chromosomal translocations to

  2013cites this paper
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• Double-hit myeloma with IGH/MYC and IGH/CCND1 translocations

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• Breakthroughs in the Management of Multiple Myeloma

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• Increased expression of cyclin‐D1 on trephine bone marrow biopsies independently predicts for shorter overall survival in patients with multiple myeloma treated with novel agents

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  2011cites this paper
• Article Title: A compendium of myeloma associated chromosomal copy number abnormalities and their prognostic value Short Title: SNP-based genome mapping in myeloma

  2010cites this paper
• Title : A compendium of myeloma associated chromosomal copy number abnormalities and their prognostic value Short Title : SNP-based genome mapping in myeloma

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• A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value.

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• Prognostic factors for multiple myeloma in the era of novel agents.

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• SPOTLIGHT REVIEW Pathogenesis and progression of monoclonal gammopathy of undetermined significance

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• Role of genetics in prognostication in myeloma.

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• Mieloma múltiple quiescente: Historia natural y caracterización clínica y citogenética del tipo progresivo

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• CARATTERIZZAZIONE CITOGENETICO- MOLECOLARE IN PAZIENTI CON MIELOMA MULTIPLO. IMPLICAZIONI PROGNOSTICHE DELLE DELEZIONI DEL CROMOSOMA 13 E DEL CROMOSOMA 17

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• Prognostic impact of cytogenetic aberrations in patients with multiple myeloma or monoclonal gammopathy of unknown significance

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• Clinical Significance of Cytogenetics in Multiple Myeloma and Chronic Lymphocytic Leukemia

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• Molecular biology and cytogenetics

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• Acquired Robertsonian translocations are not rare events in acute leukemia and lymphoma.

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• The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant

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• A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age‐ and sex‐related differences

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• Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy.

  2002influential citation
• TPA stimulation culture for improved detection of t(11;14)(q13;q32) in mantle cell lymphoma.

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• Establishment of CD7+ Human Myeloma Sister Cell Lines, KMS-21-PE and KMS-21-BM, Carrying t(11;14) and t(8;14)

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• Cyclin D 3 at 6 p 21 is dysregulated by recurrent chromosomal translocations to immunoglobulin loci in multiple myeloma

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• Immunohistochemical analysis of cyclin D1 shows deregulated expression in multiple myeloma with the t(11;14).

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• Expression of fibroblast growth factor and FGF-receptor family genes in human myeloma cells, including lines possessing t(4;14)(q16.3;q32. 3) and FGFR3 translocation.

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• 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma. Intergroupe Francophone du Myélome.

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• Clinical significance of the translocation (11;14)(q13;q32) in multiple myeloma.

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• Multiple myeloma and the translocation t(11;14)(q13;q32): a report on 13 cases

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• Cytogenetic analysis of 280 patients with multiple myeloma and related disorders: Primary breakpoints and clinical correlations

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