Plasma cell karyotype in multiple myeloma.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Blood

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1182/blood.v71.2.453.453PMID 3337907
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1988cited by this paper
• The role of chromosomal translocations in B- and T-cell neoplasia.

  1987cited by this paper
• Chromosome findings in multiple myeloma.

  1987cited by this paper
• Translocation (14;18) found in a patient with multiple myeloma.

  1987cited by this paper
• Analysis of G banded karyotypes in myeloma cells.

  1986cited by this paper
• Prognostic implications of tumor cell DNA and RNA content in multiple myeloma

  1985cited by this paper
• Cytoplasmic immunoglobulin content in multiple myeloma.

  1985cited by this paper
• Prognostic implications of tumor cell DNA and RNA content in multiple myeloma.

  1985cited by this paper
• The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis.

  1985cited by this paper
• Chromosome abnormalities in malignant hematologic disorders.

  1985cited by this paper
• Genes and chromosomes in human cancer.

  1985cited by this paper
• Cytogenetic study in multiple myeloma.

  1984cited by this paper
• Non‐random chromosomal aberrations associated with multiple myeloma

  1984cited by this paper
• High incidence of chromosome abnormalities in IgG3 myeloma.

  1984cited by this paper
• High-dose melphalan for multiple myeloma.

  1983cited by this paper
• A Burkitt-type 8;14 translocation in a case of plasma cell leukemia.

  1983cited by this paper
• Myeloma protein kinetics following chemotherapy.

  1982cited by this paper
• Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

  1982cited by this paper
• Ploidy and proliferative characteristics in monoclonal gammopathies.

  1982cited by this paper
• Chromosomes and survival in multiple myeloma. A banding study of 25 cases

  1980cited by this paper
• Characterization of hematologic malignancies by flow cytometry.

  1980cited by this paper
• Chromosomes of monoclonal gammopathies

  1980cited by this paper
• Characterization of hematologic malignancies by flow cytometry.

  1980cited by this paper
• Karyotypic abnormalities and clinical aspects of patients with multiple myeloma and related paraproteinemic disorders

  1979cited by this paper
• Correlation of DNA distribution abnormalities with cytogenetic findings in human adult leukemia and lymphoma.

  1977cited by this paper
• G-banding analysis of complex aneuploidy in multiple myeloma bone marrow cells.

  1976cited by this paper
• Chromosome banding techniques.

  1976cited by this paper

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• Multiple Myeloma: Methods and Protocols

  2020cites this paper
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  2018cites this paper
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  2018cites this paper
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  2014cites this paper
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  2014cites this paper
• Cytogenetic classification in Korean multiple myeloma patients: prognostic significance of hyperdiploidy with 47–50 chromosomes and the number of structural abnormalities

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  2012cites this paper
• Prognostic power of abnormal cytogenetics for multiple myeloma: a multicenter study in China.

  2012cites this paper
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  2010cites this paper
• Multiple myeloma: biology of the disease.

  2010cites this paper
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  2009cites this paper
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  2009cites this paper
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• Treatment of newly diagnosed multiple myeloma based on Mayo Stratification of Myeloma and Risk-adapted Therapy (mSMART): consensus statement.

  2007cites this paper
• [Comparison of the rate of detection of immunoglobulin heavy chain gene rearrangement by fluoresecence in situ hybridization probes in multiple myeloma.].

  2006cites this paper
• Cytogenetics and molecular cytogenetics in multiple myeloma.

  2006cites this paper
• Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma

  2005cites this paper
• Genetics of multiple myeloma.

  2005cites this paper
• Genetic heterogeneity in multiple myeloma

  2005cites this paper
• A neurotrophin axis in myeloma: TrkB and BDNF promote tumor-cell survival.

  2005cites this paper
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• Frequent gains of the short arm of chromosome 9 in multiple myeloma with normal G-banded karyotype detected by comparative genomic hybridization.

  2004cites this paper
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  2004cites this paper
• B‐prolymphocytic leukaemia with t(11;14) revisited: a splenomegalic form of mantle cell lymphoma evolving with leukaemia

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• Induction of CD28 on the new myeloma cell line MOLP-8 with t(11;14)(q13;q32) expressing delta/lambda type immunoglobulin.

  2004cites this paper
• Genetics and Cytogenetics of Multiple Myeloma: A Workshop Report

  2004cites this paper
• A pooled analysis of karyotypic patterns, breakpoints and imbalances in 783 cytogenetically abnormal multiple myelomas reveals frequently involved chromosome segments as well as significant age‐ and sex‐related differences

  2003cites this paper
• MDS‐type abnormalities within myeloma signature karyotype (MM‐MDS): only 13% 1‐year survival despite tandem transplants

  2003cites this paper
• Heterogeneous pattern of chromosomal breakpoints involving the MYC locus in multiple myeloma

  2003cites this paper
• Cytogenetics of multiple myeloma: interpretation of fluorescence in situ hybridization results

  2003cites this paper
• [Cytogenetic abnormalities in malignant lymphoma and multiple myeloma].

  2003cites this paper
• Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization‐defined chromosome 13 deletion in multiple myeloma: early results of total therapy II

  2003cites this paper
• Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy.

  2002influential citation
• Molecular aspects of multiple myeloma

  2002cites this paper
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• Detection of 13q abnormalities in multiple myeloma using immunomagnetically selected plasma cells.

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  2000cites this paper
• ROLE OF INTERLEUKIN‐6 IN THE PATHOGENESIS OF MULTIPLE MYELOMA

  2000cites this paper
• Molecular aspects of multiple myeloma.

  2000cites this paper
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  2000cites this paper
• High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH.

  2000influential citation
• The biology of multiple myeloma

  2000cites this paper
• Diagnostic and Therapeutic Advances in Hematologic Malignancies

  1999influential citation
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  1998cites this paper
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• Bcl-1/cyclin D1 in malignant lymphoma.

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