Many panels of ancestry informative single nucleotide polymorphisms have been proposed in recent years for various purposes including detecting stratification in biomedical studies and determining an individual's ancestry in a forensic context. All of the panels have limitations in their generality and efficiency for routine forensic work. Some panels have used only a few populations to validate them. Some panels are based on very large numbers of SNPs thereby limiting the ability of others to test different populations. We have been working toward an efficient and globally useful panel of ancestry informative markers that is comprised of a small number of highly informative SNPs. We have developed a panel of 55 SNPs analyzed on 73 populations from around the world. We present the details of the panel and discuss its strengths and limitations.
Progress toward an efficient panel of SNPs for ancestry inference.
K. Kidd,W. Speed,A. Pakstis,M. Furtado,Rixun Fang,Abeer Madbouly,M. Maiers,Mridu Middha,F. Friedlaender,J. Kidd
Published 2014 in Forensic Science International: Genetics
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- Publication year
2014
- Venue
Forensic Science International: Genetics
- Publication date
2014-05-01
- Fields of study
Biology, Medicine
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Semantic Scholar, PubMed
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