Coordinating cytoskeletal tracks to polarize cellular movements

For many years after the discovery of actin filaments and microtubules, it was widely assumed that their polymerization, organization, and functions were largely distinct. However, in recent years it has become increasingly apparent that coordinated interactions between microtubules and filamentous actin are involved in many polarized processes, including cell shape, mitotic spindle orientation, motility, growth cone guidance, and wound healing. In the past few years, significant strides have been made in unraveling the intricacies that govern these intertwined cytoskeletal rearrangements.

• Publication year

  2004

• Venue

  Journal of Cell Biology

• Publication date

  2004-10-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.200408047PMID 15504907PMCID 2172533
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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