Role of the cytoskeleton in flow (shear stress)-induced dilation and remodeling in resistance arteries

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Medical and Biological Engineering and Computing

• Publication date

  2008-02-02

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1007/s11517-008-0306-2PMID 18246377PMCID PMC2566739
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• New approaches in the therapy of cardiomyopathy in muscular dystrophy.

  2007cited by this paper
• Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell.

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• Phenotypic Heterogeneity of the Endothelium: I. Structure, Function, and Mechanisms

  2007cited by this paper
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• The role of the renin-angiotensin system and oxidative stress in spontaneously hypertensive rat mesenteric collateral growth impairment.

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• Expression and function of utrophin associated protein complex in stretched endothelial cells: dissociation and activation of eNOS.

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• Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats.

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• Phenotypic Heterogeneity of the Endothelium: II. Representative Vascular Beds

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• Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm.

  2007cited by this paper
• Heparin Impairs Glycocalyx Barrier Properties and Attenuates Shear Dependent Vasodilation in Mice

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• Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture).

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• Readthrough strategies for stop codons in Duchenne muscular dystrophy.

  2006cited by this paper
• Rho kinases in cardiovascular physiology and pathophysiology.

  2006cited by this paper
• Role of Small GTPases in Endothelial Cytoskeletal Dynamics and the Shear Stress Response

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• Key Role of the NO-Pathway and Matrix Metalloprotease-9 in High Blood Flow-Induced Remodeling of Rat Resistance Arteries

  2006cited by this paper
• Opsoclonus-myoclonus associated with celiac disease.

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• Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels.

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• Molecular mechanisms of the vascular responses to haemodynamic forces

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• The endothelial glycocalyx: a potential barrier between health and vascular disease

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• Making up and breaking up: the tortuous ways of the vascular wall.

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• Pressure and flow-dependent tone in resistance arteries. Role of myogenic tone.

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• Shear Stress Biology of the Endothelium

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• Mechanotransduction in endothelial cell migration

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• p47phox-Dependent NADPH Oxidase Regulates Flow-Induced Vascular Remodeling

  2005influential reference
• Role of Focal Adhesion Kinase in Flow-Induced Dilation of Coronary Arterioles

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• The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma.

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• Association between platelet endothelial cellular adhesion molecule 1 (PECAM-1/CD31) polymorphisms and acute myocardial infarction: a study in patients from Sicily.

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• The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a "bumper-car" model.

  2004influential reference
• Coordinating cytoskeletal tracks to polarize cellular movements

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• Role of the Rhoa/Rho Kinase System in Flow-Related Remodeling of Rat Mesenteric Small Arteries in Vivo

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• Mechanotransduction and flow across the endothelial glycocalyx

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• Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro.

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• Chronic hydralazine improves flow (shear stress)-induced endothelium-dependent dilation in mouse mesenteric resistance arteries in vitro.

  2002cited by this paper
• Defect in Microvascular Adaptation to Chronic Changes in Blood Flow in Mice Lacking the Gene Encoding for Dystrophin

  2002influential reference
• Impaired collateral development in mature rats.

  2002influential reference
• Fluid Shear Stress Activates Proline-Rich Tyrosine Kinase via Reactive Oxygen Species–Dependent Pathway

  2002cited by this paper
• Small artery remodeling and significance in the development of hypertension.

  2002cited by this paper
• Role of protein kinase C- or RhoA-induced Ca(2+) sensitization in stretch-induced myogenic tone.

  2002cited by this paper
• Pressure‐induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior

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• Excessive Microvascular Adaptation to Changes in Blood Flow in Mice Lacking Gene Encoding for Desmin

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• Adaptation of Resistance Arteries to Increases in Pressure

  2002cited by this paper
• Mechanical Signaling and the Cellular Response to Extracellular Matrix in Angiogenesis and Cardiovascular Physiology

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• Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology.

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• Endothelial microtubule disruption blocks flow-dependent dilation of arterioles.

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• Smooth Muscle Cell Changes During Flow-Related Remodeling of Rat Mesenteric Resistance Arteries

  2001cited by this paper
• Flow Pulsatility Is a Critical Determinant of Oxidative Stress in Endothelial Cells

  2001cited by this paper
• Flow (Shear Stress)–Induced Endothelium-Dependent Dilation Is Altered in Mice Lacking the Gene Encoding for Dystrophin

  2001influential reference
• Endothelial Barrier Function under Laminar Fluid Shear Stress

  2000cited by this paper
• Altered flow-induced arterial remodeling in vimentin-deficient mice.

  2000influential reference
• Rapid displacement of vimentin intermediate filaments in living endothelial cells exposed to flow.

  2000cited by this paper
• Tissue angiotensin II and endothelin‐1 modulate differently the response to flow in mesenteric resistance arteries of normotensive and spontaneously hypertensive rats

  2000cited by this paper
• Vascular remodelling of resistance vessels: can we define this?

  1999cited by this paper
• Activation of AT(2) receptors by endogenous angiotensin II is involved in flow-induced dilation in rat resistance arteries.

  1999cited by this paper
• Flow-induced arterial remodeling in rat mesenteric vasculature.

  1998cited by this paper
• Correlation of endothelial vimentin content with hemodynamic parameters

  1998cited by this paper
• Chronic endothelin-1-induced changes in vascular reactivity in rat resistance arteries and aorta.

  1998cited by this paper
• Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts.

  1998cited by this paper
• Flow-induced arterial remodeling in rat mesenteric vasculature.

  1998cited by this paper
• Vasomotor responses in chronically hyperperfused and hypoperfused rat mesenteric arteries.

  1998cited by this paper
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  1997cited by this paper
• Structural properties of rat mesenteric small arteries after 4-wk exposure to elevated or reduced blood flow.

  1997cited by this paper
• Integrin signaling transduces shear stress--dependent vasodilation of coronary arterioles.

  1997cited by this paper
• Nitric oxide induces heat-shock protein 70 expression in vascular smooth muscle cells via activation of heat shock factor 1.

  1997cited by this paper
• In vitro modulation of a resistance artery diameter by the tissue renin-angiotensin system of a large donor artery.

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• Structural properties of rat mesenteric small arteries after 4-wk exposure to elevated or reduced blood flow.

  1997cited by this paper
• Impaired flow-induced dilation in mesenteric resistance arteries from mice lacking vimentin.

  1997influential reference
• Wall remodeling during luminal expansion of mesenteric arterial collaterals in the rat.

  1996cited by this paper
• Anionic biopolymers as blood flow sensors.

  1996cited by this paper
• Arterial remodeling: relation to hemodynamics.

  1996cited by this paper
• Mechanotransduction through the endothelial cytoskeleton: mediation of flow‐ but not agonist‐induced EDRF release

  1996cited by this paper
• Fluid shear stress induces the phosphorylation of small heat shock proteins in vascular endothelial cells.

  1996cited by this paper
• Flow-mediated endothelial mechanotransduction.

  1995cited by this paper
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  1995cited by this paper
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• Exercise training augments flow-dependent dilation in rat skeletal muscle arterioles. Role of endothelial nitric oxide and prostaglandins.

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  1994cited by this paper
• Mice lacking vimentin develop and reproduce without an obvious phenotype.

  1994cited by this paper
• Pharmacological implications of the flow-dependence of vascular smooth muscle tone.

  1994influential reference
• Vascular free radical release. Ex vivo and in vivo evidence for a flow-dependent endothelial mechanism.

  1994cited by this paper
• Role of Ca2+ and protein kinase C in shear stress-induced actin depolymerization and endothelin 1 gene expression.

  1994cited by this paper
• Dystrophin as a mechanochemical transducer in skeletal muscle.

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• EDRF-mediated shear-induced dilation opposes myogenic vasoconstriction in small rabbit arteries.

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• Blood vessel wall matrix flow sensor: evidence and speculation.

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  1980cited by this paper

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