Rme-1 regulates the recycling of the cystic fibrosis transmembrane conductance regulator.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  American Journal of Physiology - Cell Physiology

• Publication date

  2003-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPCELL.00140.2003PMID 12839834
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Role of the C Terminus and Na+/H+ Exchanger Regulatory Factor in the Functional Expression of Cystic Fibrosis Transmembrane Conductance Regulator in Nonpolarized Cells and Epithelia*

  2003cited by this paper
• A Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Generates a Novel Internalization Sequence and Enhances Endocytic Rates*

  2003cited by this paper
• PDZ Domain Interaction Controls the Endocytic Recycling of the Cystic Fibrosis Transmembrane Conductance Regulator*

  2002cited by this paper
• Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart.

  2002cited by this paper
• Analysis of CFTR endocytosis by cell surface biotinylation.

  2002cited by this paper
• Evidence that RME-1, a conserved C. elegans EH-domain protein, functions in endocytic recycling

  2001cited by this paper
• The Metabolic and Molecular Bases of Inherited Disease

  2001cited by this paper
• Rme-1 regulates the distribution and function of the endocytic recycling compartment in mammalian cells

  2001cited by this paper
• μ2 Binding Directs the Cystic Fibrosis Transmembrane Conductance Regulator to the Clathrin-mediated Endocytic Pathway*

  2001cited by this paper
• The ΔF508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells

  2001cited by this paper
• Multiple endocytic signals in the C-terminal tail of the cystic fibrosis transmembrane conductance regulator.

  2001cited by this paper
• The Delta F508 mutation shortens the biochemical half-life of plasma membrane CFTR in polarized epithelial cells.

  2001cited by this paper
• Insulin-responsive Aminopeptidase Trafficking in 3T3-L1 Adipocytes*

  2000cited by this paper
• The Carboxyl Terminus of the Cystic Fibrosis Transmembrane Conductance Regulator Binds to AP-2 Clathrin Adaptors*

  2000cited by this paper
• EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins.

  2000cited by this paper
• Inhibition of cystic fibrosis transmembrane conductance regulator by novel interaction with the metabolic sensor AMP-activated protein kinase.

  2000cited by this paper
• Subcellular distribution of CFTR in rat intestine supports a physiologic role for CFTR regulation by vesicle traffic

  2000cited by this paper
• EHD1--an EH-domain-containing protein with a specific expression pattern.

  1999cited by this paper
• Syntaxin 1A inhibits regulated CFTR trafficking in xenopus oocytes.

  1999cited by this paper
• Efficient Endocytosis of the Cystic Fibrosis Transmembrane Conductance Regulator Requires a Tyrosine-based Signal*

  1999influential reference
• Intracellular CFTR: localization and function.

  1999cited by this paper
• Characterization of the internalization pathways for the cystic fibrosis transmembrane conductance regulator.

  1999cited by this paper
• A PDZ-interacting domain in CFTR is an apical membrane polarization signal.

  1999cited by this paper
• An Apical PDZ Protein Anchors the Cystic Fibrosis Transmembrane Conductance Regulator to the Cytoskeleton*

  1998cited by this paper
• G protein regulation of potassium ion channels.

  1998cited by this paper
• Peptide binding consensus of the NHE‐RF‐PDZ1 domain matches the C‐terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)

  1998cited by this paper
• Identification of an Insulin-responsive, Slow Endocytic Recycling Mechanism in Chinese Hamster Ovary Cells*

  1998cited by this paper
• Endocytosis.

  1997cited by this paper
• Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

  1997cited by this paper
• Constitutive internalization of cystic fibrosis transmembrane conductance regulator occurs via clathrin-dependent endocytosis and is regulated by protein phosphorylation.

  1997cited by this paper
• Membrane transport in the endocytic pathway.

  1995cited by this paper
• Studies of Transferrin Recycling Reconstituted in Streptolysin O Permeabilized Chinese Hamster Ovary Cells (*)

  1995cited by this paper
• Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles.

  1994cited by this paper
• Subcellular localization of CFTR to endosomes in a ductal epithelium.

  1994cited by this paper
• The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

  1993cited by this paper
• The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant of endosomal pH.

  1992cited by this paper
• The Cystic Fibrosis Transmembrane Regulator Is Present and Functional in Endosomes

  1992cited by this paper
• Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization

  1990cited by this paper
• Iterative fractionation of recycling receptors from lysosomally destined ligands in an early sorting endosome

  1989cited by this paper
• Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

  1989cited by this paper
• Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA

  1989cited by this paper
• Segregation of transferrin to a mildly acidic (pH 6.5) para-Golgi compartment in the recycling pathway.

  1984cited by this paper

• Amelioration of airway and GI disease in G551D-CF ferrets by AAV1 and AAV6

  2024cites this paper
• CFTR and Cystic Fibrosis: A Need for Personalized Medicine

  2020cites this paper
• Protein kinase Cε activation induces EHD-dependent degradation and downregulation of KATP channels: Implications for glucose stimulated insulin secretion

  2020influential citation
• Cystic Fibrosis, Cystic Fibrosis Transmembrane Conductance Regulator and Drugs: Insights from Cellular Trafficking.

  2018cites this paper
• Trafficking Ion Transporters to the Apical Membrane of Polarized Intestinal Enterocytes.

  2018cites this paper
• Targeting Trafficking in Drug Development

  2018cites this paper
• Sorting Nexin 27 (SNX27): A Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Trafficking

  2018cites this paper
• The role of intracellular Ca2+ in cigarette smoke-induced CFTR internalisation

  2017cites this paper
• Activation of TPA-response element present in human Lemur Tyrosine Kinase 2 (lmtk2) gene increases its expression

  2017cites this paper
• Modulate its Internalization Differently

  2016cites this paper
• From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking

  2016cites this paper
• Increased Expression of Eps15 Homology Domain 1 is Associated with Poor Prognosis in Resected Small Cell Lung Cancer

  2015cites this paper
• A Role for EHD Family Endocytic Regulators in Endothelial Biology

  2015cites this paper
• Renal Epithelial Cell Transport Regulation Sorting It Out in Endosomes: An Emerging Concept in

  2015cites this paper
• Functional characterization of the roles of endocytic recycling regulator EHD1 using in vivo and in vitro analyses

  2015cites this paper
• Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria*

  2015cites this paper
• Decreased expression and prognostic role of EHD2 in human breast carcinoma: correlation with E-cadherin

  2015cites this paper
• Biosynthesis of cystic fibrosis transmembrane conductance regulator.

  2014cites this paper
• Quantitative Proteomic Profiling Reveals Differentially Regulated Proteins in Cystic Fibrosis Cells

  2014cites this paper
• Regulated recycling of mutant CFTR is partially restored by pharmacological treatment

  2013influential citation
• Stimulation de cellules épithéliales bronchiques humaines par la GnRH : effet sur le transport ionique médié par le CFTR

  2013cites this paper
• Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR.

  2013cites this paper
• Can correcting the ΔF508-CFTR proteostasis-defect rescue CF lung disease?

  2012cites this paper
• TNAP and EHD1 Are Over-Expressed in Bovine Brain Capillary Endothelial Cells after the Re-Induction of Blood-Brain Barrier Properties

  2012cites this paper
• Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator.

  2012cites this paper
• The role of cystic fibrosis conductance regulator in the clearance of Burkholderia cenocepacia by macrophages

  2012cites this paper
• Trafficking of an endogenous potassium channel in adult ventricular myocytes.

  2012cites this paper
• Fluorescence Platform Development for Detection of Cystic Fibrosis Transmembrane Conductance Regulator Trafficking

  2011cites this paper
• Pre‐Sorting Endosomal Transport of the GPI‐Anchored Protein, CD59, is Regulated by EHD1

  2011cites this paper
• NRC Publications Archive Archives des publications du CNRC

  2011cites this paper
• The Cystic Fibrosis Transmembrane Conductance Regulator's Expanding SNARE Interactome

  2011cites this paper
• Les protéines Gα12 et Gα13 dans la mucoviscidose : Rôle dans la dégradation de la protéine CFTR mutée F508del et dans le contrôle des jonctions intercellulaires.

  2011cites this paper
• Physiological relevance of cell-specific distribution patterns of CFTR, NKCC1, NBCe1, and NHE3 along the crypt-villus axis in the intestine.

  2011cites this paper
• Rab11b and its effector Rip11 regulate the acidosis‐induced traffic of V‐ATPase in salivary ducts

  2011cites this paper
• Endocytic sorting of CFTR variants monitored by single-cell fluorescence ratiometric image analysis (FRIA) in living cells.

  2011cites this paper
• EHD2 mediates trafficking from the plasma membrane by modulating Rac1 activity.

  2011cites this paper
• COMMD1-Mediated Ubiquitination Regulates CFTR Trafficking

  2011cites this paper
• EHD proteins: key conductors of endocytic transport.

  2011cites this paper
• APLP1 and Rab5A Interact with the II-III loop of the Voltage-gated Ca2+-channel Cav2.3 and Modulate its Internalization Differently

  2011cites this paper
• Dab 2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator

  2011cites this paper
• Syntaxin 3 is necessary for cAMP- and cGMP-regulated exocytosis of CFTR: implications for enterotoxigenic diarrhea.

  2010cites this paper
• Syntaxin 16 Binds to Cystic Fibrosis Transmembrane Conductance Regulator and Regulates Its Membrane Trafficking in Epithelial Cells*

  2010cites this paper
• Sorting it out in endosomes: an emerging concept in renal epithelial cell transport regulation.

  2010cites this paper
• Recycling of the Ca2+-activated K+ Channel, KCa2.3, Is Dependent upon RME-1, Rab35/EPI64C, and an N-terminal Domain*

  2010cites this paper
• Collapsin Response Mediator Protein-2 (Crmp2) Regulates Trafficking by Linking Endocytic Regulatory Proteins to Dynein Motors*

  2010cites this paper
• Polarized traffic towards the cell surface: how to find the route

  2010cites this paper
• Genes and Nutrition

  2010cites this paper
• Regulation of the epithelial sodium channels (ENaC) by small G proteins and phosphatidylinositides

  2009cites this paper
• Regulation of the epithelial sodium channels by small G-proteins and phosphatidylinositides

  2009cites this paper
• Numb Regulates Post-endocytic Trafficking and Degradation of Notch1*

  2009cites this paper
• A model for the role of EHD1-containing membrane tubules in endocytic recycling

  2009cites this paper
• The recycling endosome is required for transport of retrograde toxins

  2009cites this paper
• EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology

  2009cites this paper
• Role of Membrane Tubulation in NPC1-Mediated Cholesterol Efflux

  2009cites this paper
• Potassium Channel Silencing by Constitutive Endocytosis and Intracellular Sequestration*

  2009cites this paper
• Eps15 homology domain 1-associated tubules contain phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate and are required for efficient recycling.

  2009cites this paper
• Regulation of the epithelial sodium channel by membrane trafficking.

  2009cites this paper
• Chemotoxicity of doxorubicin and surface expression of P-glycoprotein (MDR1) is regulated by the Pseudomonas aeruginosa toxin Cif.

  2008cites this paper
• EHDS are serine phosphoproteins: EHD1 phosphorylation is enhanced by serum stimulation

  2008cites this paper
• CFTR function and prospects for therapy.

  2008cites this paper
• Intracellular Neutralization of Shiga Toxin 2 by an A Subunit-Specific Human Monoclonal Antibody

  2008cites this paper
• A Role for EHD4 in the Regulation of Early Endosomal Transport

  2008cites this paper
• The Endocytic Recycling Protein EHD2 Interacts with Myoferlin to Regulate Myoblast Fusion*

  2008cites this paper
• BREK/LMTK2 is a myosin VI‐binding protein involved in endosomal membrane trafficking

  2008cites this paper
• Volume expansion stimulates monoubiquitination and endocytosis of surface-expressed skate anion-exchanger isoform.

  2008cites this paper
• Rôles des interactions interdomaines dans le comportement cellulaire de la protéine CFTR

  2008cites this paper
• Osmoregulation of chloride channels in epithelial cells

  2008cites this paper
• Restoration of cystic fibrosis transmembrane conductance regulator function to CF mutants by enhancing protein processing and channel activity

  2008cites this paper
• A Study of the Interactors of Eps15 Homology Domain and the Role of the EH Network in the Model System of Caenohabditis elegans

  2008cites this paper
• Mechanisms of EHD/RME‐1 Protein Function in Endocytic Transport

  2008cites this paper
• ATP depletion inhibits the endocytosis of ClC‐2

  2008cites this paper
• Ion Channel Regulation by Ras, Rho, and Rab Small GTPases

  2007cites this paper
• Shared as well as distinct roles of EHD proteins revealed by biochemical and functional comparisons in mammalian cells and C. elegans

  2007cites this paper
• A novel internal binding motif in the CFTR C-terminus enhances EBP50 multimerization and facilitates endocytic recycling

  2007cites this paper
• Cell surface dynamics of CFTR: the ins and outs.

  2007cites this paper
• Cholesterol Depletion and Genistein as Tools to Promote F508delCFTR Retention at the Plasma Membrane

  2007cites this paper
• EHD proteins are associated with tubular and vesicular compartments and interact with specific phospholipids.

  2007cites this paper
• CFTR surface expression and chloride currents are decreased by inhibitors of N-WASP and actin polymerization.

  2007cites this paper
• EHD1 and Eps15 Interact with Phosphatidylinositols via Their Eps15 Homology Domains*

  2007cites this paper
• Endocytic trafficking of CFTR in health and disease.

  2007influential citation
• Myosin Vb Is Required for Trafficking of the Cystic Fibrosis Transmembrane Conductance Regulator in Rab11a-specific Apical Recycling Endosomes in Polarized Human Airway Epithelial Cells*

  2007cites this paper
• Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosis.

  2007cites this paper
• EHD1 regulates β1 integrin endosomal transport: effects on focal adhesions, cell spreading and migration

  2007cites this paper
• Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment

  2007cites this paper
• The GLUT4 glucose transporter.

  2007cites this paper
• New insights into cystic fibrosis: molecular switches that regulate CFTR

  2006cites this paper
• New insights into cystic fibrosis: molecular switches that regulate CFTR

  2006cites this paper
• New insights into cystic fibrosis: molecular switches that regulate CFTR

  2006cites this paper
• Up-regulation of AMP-activated Kinase by Dysfunctional Cystic Fibrosis Transmembrane Conductance Regulator in Cystic Fibrosis Airway Epithelial Cells Mitigates Excessive Inflammation*

  2006cites this paper
• The regulation of CFTR by protein-protein interactions

  2006influential citation
• Recycling to the Plasma Membrane is Delayed in EHD1 Knockout Mice

  2006cites this paper
• Interactions between EHD proteins and Rab11-FIP2: a role for EHD3 in early endosomal transport.

  2005influential citation
• Differential Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by Interferon γ in Mast Cells and Epithelial Cells

  2005cites this paper
• C-terminal EH-domain-containing proteins: consensus for a role in endocytic trafficking, EH?

  2005cites this paper
• Processing of CFTR: Traversing the cellular maze—How much CFTR needs to go through to avoid cystic fibrosis?

  2005cites this paper
• Intracellular Processing of CFTR

  2005cites this paper
• Recycling and EH domain proteins at the synapse.

  2005cites this paper
• EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling.

  2005cites this paper
• Differential Regulation of CFTR by Interferon- γ in Mast Cells and Epithelial Cells

  2005cites this paper
• The Short Apical Membrane Half-life of Rescued ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Results from Accelerated Endocytosis of ΔF508-CFTR in Polarized Human Airway Epithelial Cells*

  2005cites this paper