FRET-based polymer materials for detection of cellular microenvironments

Abstract Effective detection of cellular microenvironments and understanding of physiological activities in living cells remain a considerable challenge. In recent years, fluorescence (or Forster) resonance energy transfer (FRET) technology has emerged as a valuable method for real-time imaging of intracellular environment with high sensitivity, specificity and spatial resolution. Particularly, polymer-based imaging systems show enhanced stability, improved biodistribution, increased dye payloads, and amplified signal/noise ratio compared with small molecular sensors. This review summarizes the recent progress in FRET-based polymeric systems for probing the physiological environments in cells.

• Publication year

  2020

• Venue

  Chinese Chemical Letters

• Publication date

  2020-06-01

• Fields of study

  Biology, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/j.cclet.2019.11.009
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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