Clinical Pharmacokinetics of Methadone

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Acta anaesthesiologica Scandinavica. Supplementum

• Publication date

  1982-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1399-6576.1982.tb01850.xPMID 6953740
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Important clinical pharmacologic considerations in the use of methadone in cancer patients.

  1979cited by this paper
• Pharmacokinetics of methadone during maintenance therapy: Pulse labeling with deuterated methadone in the steady state

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  1977cited by this paper
• Clinical effects and pharmacokinetics of racemic methadone and its optical isomers.

  1977cited by this paper
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  1975cited by this paper
• Disposition of methadone in methadone maintenance

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• The levels of methadone in the plasma in methadone maintenance

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• Quantitative determination of methadone concentrations in human blood, plasma and urine by gas chromatography.

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• Pharmacokinetics of methadone after intravenous and subcutaneous administration in domestic ferrets (Mustela putorius furo).

  2024cites this paper
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• Integrating in vitro data and physiologically based kinetic modeling-facilitated reverse dosimetry to predict human cardiotoxicity of methadone

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• The Use of Low-Dose Methadone as Add-On to Regular Opioid Therapy in Cancer-Related Pain at End of Life: A National Swedish Survey in Specialized Palliative Care

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• Comprehensive Review on Methadone-Induced QT Prolongation and Torsades

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• Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017

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• Inhibitory effect of isavuconazole, ketoconazole, and voriconazole on the pharmacokinetics of methadone in vivo and in vitro.

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• EML OPIOIDS FOR CANCER PAIN : A COMPARATIVE OVERVIEW General Index

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• Can Saliva and Plasma Methadone Concentrations Be Used for Enantioselective Pharmacokinetic and Pharmacodynamic Studies in Patients With Advanced Cancer?

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• Improved Pain Control in Terminally Ill Cancer Patients by Introducing Low-Dose Oral Methadone in Addition to Ongoing Opioid Treatment

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• In vitro assessment of 24 CYP2D6 allelic isoforms on the metabolism of methadone.

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• Metabolomics of methadone: clinical and forensic toxicological implications and variability of dose response

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• Methadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane Receptor

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• Animal studies trigger new insights on the use of methadone maintenance

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• Methadone Induces the Expression of Hepatic Drug-Metabolizing Enzymes through the Activation of Pregnane X Receptor and Constitutive Androstane Receptor

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• Interindividual Variability of Methadone Response

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• Einfluss des Cytochrom P450 Enzyms CYP2D6 auf den Metabolismus von Methadon

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• Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action

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• Metadona en el tratamiento del dolor por cáncer: experiencia del Hospital Los Montalvos, Salamanca

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• Steady-state pharmacokinetics of methadone in opioid addicts

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• Opiatentzug in Narkose

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• Methadone--metabolism, pharmacokinetics and interactions.

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• Pharmacokinetics of the oral narcotic analgesic bezitramide and preliminary observations on its effect on experimentally induced pain

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• Der opiatabhängige Patient

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• The pharmacokinetics of methadone in healthy subjects and opiate users.

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• An ad libitum schedule for conversion of morphine to methadone in advanced cancer patients: an open uncontrolled prospective study in a Chinese population

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• Muscular Atrophy in the Hemiplegic Thigh in Patients After Stroke

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• Disposition of nasal, intravenous, and oral methadone in healthy volunteers

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• Interindividual Variability of the Clinical Pharmacokinetics of Methadone

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• Exorphine (exogene Opioidpeptide) und β-Casomorphine

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• Continuous epidural infusion of racemic methadone results in effective postoperative analgesia and low plasma concentrations

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• Methadone: The Renaissance

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• Conversion From Intrathecal Morphine to Oral Methadone

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• De la metadona al LAAM: Nuevos perfiles terapéuticos. Utilidad de la monitorización terapéutica (MT)

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• Plasma concentrations of the enantiomers of methadone and therapeutic response in methadone maintenance treatment.

  2000cites this paper
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  1998cites this paper
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• An update on the clinical use of methadone for cancer pain

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• Clinical experience with oral methadone administration in the treatment of pain in 196 advanced cancer patients.

  1996cites this paper
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  1993influential citation
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  1991cites this paper
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  1990cites this paper
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  1989cites this paper
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  1987cites this paper
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  1986cites this paper
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  1986cites this paper
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