Effect of epiregulin on pancreatic beta cell growth and insulin secretion

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Growth Factors

• Publication date

  2005-01-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1080/08977190500233367PMID 16338791
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Epiregulin

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  2005cited by this paper
• Epiregulin is more potent than EGF or TGFα in promoting in vitro wound closure due to enhanced ERK/MAPK activation

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• Somatostatin inhibits glucagon-like peptide-1-induced insulin secretion and proliferation of RINm5F insulinoma cells.

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• Epiregulin is Up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth.

  2000cited by this paper
• Epiregulin, a Novel Member of the Epidermal Growth Factor Family, Is an Autocrine Growth Factor in Normal Human Keratinocytes*

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• Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors.

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• Short- and long-term effects of β-cellulin and transforming growth factor-α on β-cell function in cultured fetal rat pancreatic islets

  1999cited by this paper
• Short- and long-term effects of beta-cellulin and transforming growth factor-alpha on beta-cell function in cultured fetal rat pancreatic islets.

  1999cited by this paper
• Signaling through fibroblast growth factor receptor 2b plays a key role in the development of the exocrine pancreas.

  1999cited by this paper
• Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha.

  1999cited by this paper
• Effects of epidermal growth factor on neonatal pancreatic growth in the guinea pig

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• Soluble dominant‐negative receptor uncovers essential roles for fibroblast growth factors in multi‐organ induction and patterning

  1998cited by this paper
• Growth factor-mediated proliferation and differentiation of insulin-producing INS-1 and RINm5F cells: identification of betacellulin as a novel beta-cell mitogen.

  1998influential reference
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  1997cited by this paper
• Systemic treatment with epidermal growth factor in pigs induces ductal proliferations in the pancreas.

  1997cited by this paper
• Mechanisms involved in the effect of nitric oxide synthase inhibition on L‐arginine‐induced insulin secretion

  1997cited by this paper
• Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells.

  1996cited by this paper
• Expression of keratinocyte growth factor in embryonic liver of transgenic mice causes changes in epithelial growth and differentiation resulting in polycystic kidneys and other organ malformations.

  1996cited by this paper
• PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin

  1996cited by this paper
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  1996cited by this paper
• A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth.

  1996cited by this paper
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  1995influential reference
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  1995cited by this paper
• Molecular cloning of mouse epiregulin, a novel epidermal growth factor‐related protein, expressed in the early stage of development

  1995cited by this paper
• Epiregulin

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• A Second Pathway for Regeneration of Adult Exocrine and Endocrine Pancreas: A Possible Recapitulation of Embryonic Development

  1993cited by this paper
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• Induction of Islet Cytodifferentiation by Fetal Mesenchyme in Adult Pancreatic Ductal Epithelium

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  1983cited by this paper
• A new approach to the induction of duct epithelial hyperplasia and nesidioblastosis by cellophane wrapping of the hamster pancreas.

  1983cited by this paper
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  1982cited by this paper
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• Epitheliomesenchymal interaction in pancreatic morphogenesis.

  1962cited by this paper

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• Beta-cell adaptation unveiled: The role of myokines in insulin-resistant mice.

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  2023cites this paper
• Epiregulin as an Alternative Ligand for Leptin Receptor Alleviates Glucose Intolerance without Change in Obesity

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• Epiregulin induces leptin secretion and energy expenditure in high-fat diet-fed mice.

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• Neuregulin 1 improves complex 2-mediated mitochondrial respiration in skeletal muscle of healthy and diabetic mice

  2017cites this paper
• Expression and Function of the Epidermal Growth Factor Receptor in Physiology and Disease.

  2016cites this paper
• Epidermal growth factor receptor in pancreatic beta cell mass regulation

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• Human β-Cell Proliferation and Intracellular Signaling Part 2: Still Driving in the Dark Without a Road Map

  2014cites this paper
• Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor.

  2013cites this paper
• Betacellulin-Induced Beta Cell Proliferation and Regeneration Is Mediated by Activation of ErbB-1 and ErbB-2 Receptors

  2011cites this paper
• Analysis of a new transgenic mouse model with ß-cell-specific overexpression of human betacellulin

  2010cites this paper
• Analysis of a new transgenic mouse model with β-cell-specific overexpression of human betacellulin

  2009cites this paper
• Trefoil factor 3 stimulates human and rodent pancreatic islet beta-cell replication with retention of function.

  2008cites this paper