Expression and prognostic role of E2F transcription factors in high‐grade glioma

Patients with high‐grade glioma (HGG) suffered poor survival due to inherent or acquired therapeutic resistance and refractory recurrence. The outcome of HGG patients has improved little during the past decade. Therefore, molecular signatures are urgently needed for improving diagnosis, survival prediction and identification of therapeutic targets for HGG. E2F transcription factors (E2Fs), a family of transcription factors recognized as master regulators of cell proliferation, have been found to be involved in the pathogenesis of various tumor types.

• Publication year

  2020

• Venue

  CNS Neuroscience & Therapeutics

• Publication date

  2020-02-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/cns.13295PMID 32064771PMCID 7299000
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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