Molecular insights and therapeutic targets for diabetic endothelial dysfunction.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Circulation

• Publication date

  2009-09-29

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/CIRCULATIONAHA.108.835223PMID 19786641PMCID PMC2910587
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Metformin Prevents Progression of Heart Failure in Dogs: Role of AMP-Activated Protein Kinase

  2009cited by this paper
• Interactions between ROS and AMP kinase activity in the regulation of PGC-1alpha transcription in skeletal muscle cells.

  2009cited by this paper
• In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I

  2009cited by this paper
• AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

  2009cited by this paper
• Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase.

  2009cited by this paper
• Berberine suppresses proinflammatory responses through AMPK activation in macrophages.

  2009cited by this paper
• Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction

  2009cited by this paper
• Endothelium-Specific GTP Cyclohydrolase I Overexpression Attenuates Blood Pressure Progression in Salt-Sensitive Low-Renin Hypertension

  2008cited by this paper
• Acute Inhibition of Guanosine Triphosphate Cyclohydrolase 1 Uncouples Endothelial Nitric Oxide Synthase and Elevates Blood Pressure

  2008cited by this paper
• Reliable endothelial function testing: at our fingertips?

  2008cited by this paper
• Vascular Peptide Endothelin-1 Links Fat Accumulation With Alterations of Visceral Adipocyte Lipolysis

  2008cited by this paper
• Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes

  2008cited by this paper
• Molecular mechanisms of ghrelin-mediated endothelial nitric oxide synthase activation.

  2008cited by this paper
• Endothelin-1 levels and albuminuria in patients with type 2 diabetes mellitus.

  2008cited by this paper
• Cilostazol activates AMP-activated protein kinase and restores endothelial function in diabetes.

  2008cited by this paper
• Reactive Nitrogen Species Is Required for the Activation of the AMP-activated Protein Kinase by Statin in Vivo*

  2008cited by this paper
• Berberine improves glucose metabolism through induction of glycolysis.

  2008cited by this paper
• Oscillating Glucose Is More Deleterious to Endothelial Function and Oxidative Stress Than Mean Glucose in Normal and Type 2 Diabetic Patients

  2008cited by this paper
• Suppression of the JNK Pathway by Induction of a Metabolic Stress Response Prevents Vascular Injury and Dysfunction

  2008cited by this paper
• Thromboxane Receptor Activates the AMP-Activated Protein Kinase in Vascular Smooth Muscle Cells via Hydrogen Peroxide

  2008cited by this paper
• AMP‐ACTIVATED PROTEIN KINASE ACTIVATION AS A STRATEGY FOR PROTECTING VASCULAR ENDOTHELIAL FUNCTION

  2008cited by this paper
• AMPK and Raptor: matching cell growth to energy supply.

  2008cited by this paper
• Adiponectin protects against myocardial ischaemia-reperfusion injury via AMP-activated protein kinase, Akt, and nitric oxide.

  2008cited by this paper
• NADPH Oxidases, Reactive Oxygen Species, and Hypertension Clinical implications and therapeutic possibilities

  2008cited by this paper
• NADPH Oxidases, Reactive Oxygen Species, and Hypertension

  2008cited by this paper
• Genetics and molecular biology--protein kinase C-zeta as an AMP-activated protein kinase kinase kinase: the protein kinase C-zeta-LKB1-AMP-activated protein kinase pathway.

  2008cited by this paper
• AMPK: a key regulator of energy balance in the single cell and the whole organism

  2008cited by this paper
• Cross-Sectional Relations of Digital Vascular Function to Cardiovascular Risk Factors in the Framingham Heart Study

  2008cited by this paper
• Adenosine 5′-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype1

  2008cited by this paper
• PROactive 07: pioglitazone in the treatment of type 2 diabetes: results of the PROactive study

  2007cited by this paper
• Cellular and molecular basis of wound healing in diabetes.

  2007cited by this paper
• Evaluation of C-Reactive Protein, Endothelin-1, Adhesion Molecule(s), and Lipids as Inflammatory Markers in Type 2 Diabetes Mellitus Patients

  2007cited by this paper
• AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.

  2007cited by this paper
• Vitamin E Supplementation Reduces Cardiovascular Events in a Subgroup of Middle-Aged Individuals With Both Type 2 Diabetes Mellitus and the Haptoglobin 2-2 Genotype: A Prospective Double-Blinded Clinical Trial

  2007cited by this paper
• Role of Oxidants and Antioxidants in Atherosclerosis: Results of In Vitro and In Vivo Investigations

  2007cited by this paper
• Rosiglitazone Reduces Glucose-Induced Oxidative Stress Mediated by NAD(P)H Oxidase via AMPK-Dependent Mechanism

  2007cited by this paper
• Proteasome-Dependent Degradation of Guanosine 5-Triphosphate Cyclohydrolase I Causes Tetrahydrobiopterin Deficiency in Diabetes Mellitus

  2007cited by this paper
• Fluid Shear Stress and NO Decrease the Activity of the Hydroxy-Methylglutaryl Coenzyme A Reductase in Endothelial Cells via the AMP-Activated Protein Kinase and FoxO1

  2007cited by this paper
• Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

  2007cited by this paper
• Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes

  2007cited by this paper
• Nicotine-induced Activation of AMP-activated Protein Kinase Inhibits Fatty Acid Synthase in 3T3L1 Adipocytes

  2007cited by this paper
• Reactive Nitrogen Species Induced by Hyperglycemia Suppresses Akt Signaling and Triggers Apoptosis by Upregulating Phosphatase PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) in an LKB1-Dependent Manner

  2007cited by this paper
• Inflammation and Endothelial Activation Is Evident at Birth in Offspring of Mothers With Type 1 Diabetes

  2007cited by this paper
• Proteasome-Dependent Degradation of Guanosine 5′-Triphosphate Cyclohydrolase I Causes Tetrahydrobiopterin Deficiency in Diabetes Mellitus

  2007cited by this paper
• AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production

  2007cited by this paper
• Pioglitazone Use and Heart Failure in Patients With Type 2 Diabetes and Preexisting Cardiovascular Disease

  2007cited by this paper
• Peroxynitrite and protein tyrosine nitration of prostacyclin synthase.

  2007cited by this paper
• High Glucose Attenuates Protein S-Nitrosylation in Endothelial Cells

  2007cited by this paper
• Endothelial dysfunction in diabetes mellitus

  2007cited by this paper
• Endothelial function and dysfunction: testing and clinical relevance.

  2007cited by this paper
• A perspective on coronary revascularization in the PROactive 05 study.

  2007cited by this paper
• Nitric oxide and peroxynitrite in health and disease.

  2007cited by this paper
• Diabetic impairments in NO-mediated endothelial progenitor cell mobilization and homing are reversed by hyperoxia and SDF-1 alpha.

  2007cited by this paper
• Endothelial Nitric Oxide Synthase in Vascular Disease: From Marvel to Menace

  2006cited by this paper
• AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update endorsed by the National Heart, Lung, and Blood Institute.

  2006cited by this paper
• Endothelial Nitric Oxide Synthase–Dependent Tyrosine Nitration of Prostacyclin Synthase in Diabetes In Vivo

  2006cited by this paper
• Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthesis in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase.

  2006cited by this paper
• Nitric Oxide in the Pathogenesis of Cardiac Disease

  2006cited by this paper
• Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes.

  2006cited by this paper
• The thromboxane receptor antagonist S18886 attenuates renal oxidant stress and proteinuria in diabetic apolipoprotein E-deficient mice.

  2006cited by this paper
• Uncoupling of Endothelial Nitric Oxidase Synthase by Hypochlorous Acid: Role of NAD(P)H Oxidase–Derived Superoxide and Peroxynitrite

  2006cited by this paper
• The Efficacy and Safety of Multivitamin and Mineral Supplement Use To Prevent Cancer and Chronic Disease in Adults: A Systematic Review for a National Institutes of Health State-of-the-Science Conference

  2006cited by this paper
• Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells.

  2006cited by this paper
• Insulin sensitivity during oral glucose tolerance test and its relations to parameters of glucose metabolism and endothelial function in type 2 diabetic subjects under metformin and thiazolidinedione

  2006cited by this paper
• Statins Activate AMP-Activated Protein Kinase In Vitro and In Vivo

  2006cited by this paper
• Metformin Inhibits Cytokine-Induced Nuclear Factor &kgr;B Activation Via AMP-Activated Protein Kinase Activation in Vascular Endothelial Cells

  2006cited by this paper
• 5‐aminoimidazole‐4‐carboxamide‐1‐beta‐4‐ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial–monocyte interaction

  2006cited by this paper
• AMP-Activated Protein Kinase Is Involved in Endothelial NO Synthase Activation in Response to Shear Stress

  2006cited by this paper
• AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute.

  2006cited by this paper
• Activation of Protein Kinase Cζ by Peroxynitrite Regulates LKB1-dependent AMP-activated Protein Kinase in Cultured Endothelial Cells*

  2006cited by this paper
• Metformin Improves Endothelial Vascular Reactivity in First-Degree Relatives of Type 2 Diabetic Patients With Metabolic Syndrome and Normal Glucose Tolerance

  2006cited by this paper
• Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction: Molecular and Pathophysiological Mechanisms

  2006cited by this paper
• Differential Modulation of AMPK Signaling Pathways by Low or High Levels of Exogenous Reactive Oxygen Species in Colon Cancer Cells

  2006cited by this paper
• Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension.

  2005cited by this paper
• Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.

  2005cited by this paper
• Vascular complications in diabetes mellitus: the role of endothelial dysfunction.

  2005cited by this paper
• Diabetes Mellitus Receptor Antagonist S 18886 Prevents Enhanced Atherogenesis 2 The Thromboxane

  2005cited by this paper
• Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation

  2005cited by this paper
• Metformin improves endothelial function in patients with metabolic syndrome

  2005cited by this paper
• Estradiol-Mediated Endothelial Nitric Oxide Synthase Association With Heat Shock Protein 90 Requires Adenosine Monophosphate-Dependent Protein Kinase

  2005cited by this paper
• Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver.

  2005cited by this paper
• Wound healing and its impairment in the diabetic foot.

  2005cited by this paper
• Of the renin-angiotensin system and reactive oxygen species Type 2 diabetes and angiotensin II inhibition.

  2005cited by this paper
• Insulin resistance, obesity and the metabolic syndrome. Is there a therapeutic role for endothelin-1 antagonists?

  2005cited by this paper
• Effect of insulin treatment on prostacyclin in experimental diabetes

  2005cited by this paper
• Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial.

  2005cited by this paper
• Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of Hypertension.

  2005cited by this paper
• The PROactive study: some answers, many questions.

  2005cited by this paper
• TP receptors regulate renal hemodynamics during angiotensin II slow pressor response.

  2004cited by this paper
• Oxidative stress, antioxidants, and endothelial function.

  2004cited by this paper
• Superoxide dismutase entrapped-liposomes restore the impaired endothelium-dependent relaxation of resistance arteries in experimental diabetes.

  2004cited by this paper
• Peroxynitrite and vascular endothelial dysfunction in diabetes mellitus.

  2004influential reference
• Vascular effects of improving metabolic control with metformin or rosiglitazone in type 2 diabetes.

  2004cited by this paper
• GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats

  2004cited by this paper
• Endothelial Progenitor Cells: Characterization and Role in Vascular Biology

  2004cited by this paper
• Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

  2004cited by this paper
• AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells.

  2004cited by this paper
• 5-Aminoimidazole-4-Carboxamide-1-β-4-Ribofuranoside Inhibits Proinflammatory Response in Glial Cells: A Possible Role of AMP-Activated Protein Kinase

  2004cited by this paper
• Regulation of Endothelial Nitric Oxide Synthase by Tetrahydrobiopterin in Vascular Disease

  2004cited by this paper
• Inflammation: the link between insulin resistance, obesity and diabetes.

  2004cited by this paper

• SIRT5 promotes vascular regeneration in peripheral muscle ischemia by regulating malonylation and glycolysis.

  2026cites this paper
• Circadian rhythm and the molecular clock in endothelial function of the cardiovascular system.

  2026cites this paper
• A Road Map to Understanding Cardiovascular Disease in Diabetes: From the AHA Strategically Focused Research Network in Cardiometabolic Health and Type 2 Diabetes.

  2026cites this paper
• Endothelial Metabolic Reprogramming Links Diabetes to Atherosclerosis.

  2026cites this paper
• 7,4′‐dimethoxy‐3‐hydroxyflavone, a protease‐activated receptor 4 (PAR4) inhibitor with antioxidant activity, ameliorates diabetic endothelial dysfunction

  2025cites this paper
• Aspalathin-Rich Unfermented Aspalathus linearsis Extract Mitigates Vascular Endothelial Inflammation by Inhibiting the TNF-α/Hexokinase 2/NF-κB Signaling Pathway

  2025cites this paper
• The molecular determinants regulating redox signaling in diabetic endothelial cells

  2025cites this paper
• Regeneration of Vascular Endothelium in Different Large Vessels

  2025cites this paper
• Human Breast Milk Extracellular Vesicles Mitigate Endothelial Dysfunction

  2025cites this paper
• Therapeutic potential of mulberry (Morus alba L.) byproducts for cardiovascular diseases

  2025cites this paper
• Beneficial effects of food-medicine homologous herbs for patients with diabetic kidney disease

  2025cites this paper
• Moringa oleifera and Blood Pressure: Evidence and Potential Mechanisms

  2025cites this paper
• Trends of atherosclerosis-related mortality in adults with diabetes: A cross-sectional analysis of U.S. national data

  2025cites this paper
• Diabetes-induced edothelial dysfuction: Molecular pathways and clinical implication

  2025cites this paper
• Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPARδ in obesity and diabetes

  2025cites this paper
• Endothelial Activation Stress Index predicts all‐cause and cardiovascular mortality in patients with diabetes: A nationwide study

  2025cites this paper
• Immune Checkpoint Restoration as a Therapeutic Strategy to Halt Diabetes-Driven Atherosclerosis

  2025cites this paper
• Association between early blood glucose dynamic trajectory and mortality for critically ill patients with heart failure: Insights from real-world data.

  2024cites this paper
• Activation of heme oxygenase‐1 by laminar shear stress ameliorates high glucose‐induced endothelial cell and smooth muscle cell dysfunction

  2024cites this paper
• Endothelial KLF11 is a novel protector against diabetic atherosclerosis

  2024cites this paper
• SGLT2 inhibitor improves the prognosis of patients with coronary heart disease and prevents in-stent restenosis

  2024cites this paper
• MicroRNA‐409‐3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice

  2024cites this paper
• Design, synthesis, biological evaluations and in silico studies of (Z)-2-(2,4-dioxothiazolidin-5-ylidene)methyl)-2-ethoxyphenyl-alkyl/arylsulfonates as potential α-glucosidase inhibitors.

  2024cites this paper
• Endothelial versus Metabolic Insulin Resistance, A Descriptive Review.

  2024cites this paper
• Antioxidant, antidiabetic, and anti-inflammatory activities of flavonoid-rich fractions of Solanum anguivi Lam. fruit: In vitro and ex vivo studies

  2024cites this paper
• Endothelial dysfunction in vascular complications of diabetes: a comprehensive review of mechanisms and implications

  2024cites this paper
• Exploring the Molecular Modalities in the Pathogenesis of Diabetic Kidney Disease with a Focus on the Potential Therapeutic Implications

  2024cites this paper
• Syndecan-1 as a prognostic biomarker in COVID-19 patients: a retrospective study of a Japanese cohort

  2024cites this paper
• Predictors of non-obstructive coronary slow flow in poorly controlled type 2 diabetes mellitus: a cross-sectional study

  2024cites this paper
• Circulating levels of C1q/TNF-α‐related protein 6 (CTRP6) in coronary artery disease and its correlation with inflammatory markers

  2024cites this paper
• Intercellular adhesion molecules as novel markers of endothelial function in patients with diabetes mellitus in the South Indian population

  2024cites this paper
• Licorice Extract Isoliquiritigenin Protects Endothelial Function in Type 2 Diabetic Mice

  2024influential citation
• Protective effect of ellagic acid against high-glucose-induced injury in human umbilical venous endothelial cells

  2024cites this paper
• Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α-amylase, and α-glucosidase: synthesis, molecular docking, and ADMET studies

  2024influential citation
• Differences Between Brachial-Ankle Pulse Wave Velocity and Lower Leg Circumference Ratio in Patients With and Without Type 2 Diabetes Mellitus

  2024cites this paper
• Scavenger receptor a mediates glycated LDL transcytosis across endothelial cells to promote atherosclerosis.

  2023cites this paper
• An ischemic area-targeting, peroxynitrite-responsive, biomimetic carbon monoxide nanogenerator for preventing myocardial ischemia-reperfusion injury

  2023cites this paper
• ETV2 Enhances CXCL5 Secretion from Endothelial Cells, Leading to the Promotion of Vascular Smooth Muscle Cell Migration

  2023cites this paper
• Neuraminidase inhibition improves endothelial function in diabetic mice.

  2023cites this paper
• Dynamics of endothelial function indexes in patients with post-Covid syndrome using a combination drug of ethylmethylhydroxyperidine succinate/vitamin B6

  2023cites this paper
• Relationship between inflammatory markers and coronary slow flow in type 2 diabetic patients

  2023cites this paper
• Effect of Low Protein Diet Supplemented with Ketoanalogs on Endothelial Function and Protein-Bound Uremic Toxins in Patients with Chronic Kidney Disease

  2023cites this paper
• Ameliorating diabetes-associated atherosclerosis and diabetic nephropathy through modulation of soluble guanylate cyclase

  2023cites this paper
• The beneficial effects of astragaloside IV on ameliorating diabetic kidney disease.

  2023cites this paper
• Tripeptide IRW Improves AMPK/eNOS Signaling Pathway via Activating ACE2 in the Aorta of High-Fat-Diet-Fed C57BL/6 Mice

  2023cites this paper
• Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X

  2023cites this paper
• Impact of Glycemic Control on Coronary Inflammation Evaluated by Computed Tomography Pericoronary Fat Attenuation Index in Patients with Acute Coronary Syndrome

  2023cites this paper
• Reactive Oxygen Species in the Aorta and Perivascular Adipose Tissue Precedes Endothelial Dysfunction in the Aorta of Mice with a High-Fat High-Sucrose Diet and Additional Factors

  2023influential citation
• Stem cell-derived exosomes from human exfoliated deciduous teeth promote angiogenesis in hyperglycemic-induced human umbilical vein endothelial cells

  2023cites this paper
• Association between glycated hemoglobin and functional outcomes in patients with intracranial large artery atherosclerotic disease-related acute ischemic stroke: identifying the magic number

  2023cites this paper
• Advances in Fabrication Technologies for the Development of Next-Generation Cardiovascular Stents

  2023cites this paper
• A Reassessment of the Causal Effects of Dysglycemia on Atherosclerotic and Thrombotic Events.

  2022cites this paper
• The dual role of the hexosamine biosynthetic pathway in cardiac physiology and pathophysiology

  2022cites this paper
• Canagliflozin Inhibits Human Endothelial Cell Inflammation through the Induction of Heme Oxygenase-1

  2022cites this paper
• Role of platelet-derived growth factor c on endothelial dysfunction in cardiovascular diseases.

  2022cites this paper
• Total White Blood Cell Count is Associated with Arterial Stiffness Among Hypertensive Patients

  2022cites this paper
• Elevated Glycated Hemoglobin Levels Are Associated With Poor Outcome in Acute Ischemic Stroke

  2022cites this paper
• Divergent effect of blood glucose dysregulation on long-term clinical outcome in acute decompensated heart failure: A reappraisal in contemporary practice.

  2022cites this paper
• Old and Novel Therapeutic Approaches in the Management of Hyperglycemia, an Important Risk Factor for Atherosclerosis

  2022cites this paper
• Thermal dysregulation in patients with multiple sclerosis during SARS-CoV-2 infection. The potential therapeutic role of exercise

  2022cites this paper
• Structurally diverse polycyclic polyprenylated acylphloroglucinols with protective effect on human vein endothelial cells injured by high-glucose from Hypericum acmosepalum N. Robson.

  2022cites this paper
• Preparation of thermo-responsive polymer encapsulated exosomes and its role as a therapeutic agent for blood clot lysis.

  2022cites this paper
• Identification of Risk Factors for Coronary Artery Disease in Asymptomatic Patients with Type 2 Diabetes Mellitus

  2022cites this paper
• The expression profile of circANKRD36 and ANKRD36 as diagnostic biomarkers of chronic kidney disease in patients with type 2 diabetes mellitus

  2021cites this paper
• Relevance of N6-methyladenosine regulators for transcriptome: Implications for development and the cardiovascular system.

  2021cites this paper
• Relationship of Homocysteine Plasma Levels with Mild Cognitive Impairment, Alzheimer’s Disease, Vascular Dementia, Psychobehavioral, and Functional Complications

  2021cites this paper
• Isoliquiritigenin attenuates inflammation and modulates Nrf2/caspase-3 signalling in STZ-induced aortic injury.

  2021cites this paper
• Investigation of the impacts of zamzam water on streptozotocin-induced diabetic nephropathy in rats. In-vivo and in-vitro study.

  2021cites this paper
• Peroxidasin promotes diabetic vascular endothelial dysfunction induced by advanced glycation end products via NOX2/HOCl/Akt/eNOS pathway

  2021cites this paper
• Herbal medicine use to treat andrological problems: Asian and Indian subcontinent: Ginkgo biloba, Curcuma longa, and Camellia sinensis

  2021cites this paper
• COVID-19 and Venous Thromboembolism: From Pathological Mechanisms to Clinical Management

  2021cites this paper
• Overexpression of E3 ubiquitin ligase Cbl attenuates endothelial dysfunction in diabetes mellitus by inhibiting the JAK2/STAT4 signaling and Runx3-mediated H3K4me3

  2021cites this paper
• Silent coronary artery disease in type 2 diabetes: a narrative review on epidemiology, risk factors, and clinical studies

  2021cites this paper
• Endothelial mineralocorticoid receptor ablation confers protection towards endothelial dysfunction in experimental diabetes in mice

  2021cites this paper
• A GLP-1 analog lowers ER stress and enhances protein folding to ameliorate homocysteine-induced endothelial dysfunction

  2021cites this paper
• Low Vitamin D Levels are Associated with Vascular Endothelial Dysfunction in Patients with Poorly Controlled Type 2 Diabetes: A Retrospective Study

  2021cites this paper
• Higher susceptibility to heme oxidation and lower protein stability of the rare α1C517Yβ1 sGC variant associated with moyamoya syndrome.

  2021cites this paper
• The nexus between redox state and intermediary metabolism

  2021cites this paper
• Nutrition and Periodontal Health in the Patients with Diabetes Mellitus: a Review from the Viewpoint of Endothelial Function

  2021cites this paper
• Assessment of heart rate variability (HRV) in subjects with type 2 diabetes mellitus with and without diabetic foot: correlations with endothelial dysfunction indices and markers of adipo-inflammatory dysfunction

  2021cites this paper
• Effects of Sodium-Glucose Co-Transporter 2 Inhibitors on Vascular Cell Function and Arterial Remodeling

  2021cites this paper
• Adipose Tissue-Endothelial Cell Interactions in Obesity-Induced Endothelial Dysfunction

  2021cites this paper
• Impact of glycemic control on the association of endothelial dysfunction and coronary artery disease in patients with type 2 diabetes mellitus

  2021cites this paper
• Adenosine Monophosphate-Activated Protein Kinase, Oxidative Stress, and Diabetic Endothelial Dysfunction

  2021cites this paper
• Perspectives on the Potential Benefits of Antihypertensive Peptides towards Metabolic Syndrome

  2020influential citation
• C1q/TNF-related protein 5 contributes to diabetic vascular endothelium dysfunction through promoting Nox-1 signaling

  2020cites this paper
• Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction

  2020cites this paper
• Type 1 diabetes increases retention of

  2020cites this paper
• Glucose-insulin-potassium infusion for the treatment of acute aluminum phosphide poisoning: an open-label pilot study

  2020cites this paper
• The Vascular Consequences of Metabolic Syndrome: Rodent Models, Endothelial Dysfunction, and Current Therapies

  2020cites this paper
• Low-concentration exposure to organochlorine pesticides (OCPs) in L6 myotubes and RIN-m5F pancreatic beta cells induces disorders of glucose metabolism.

  2020cites this paper
• The Endothelial Dysfunction and Pyroptosis Might Drive the SARS-CoV-2 Lung Injury to the Systemic Immunothrombosis

  2020cites this paper
• Potential cardiovascular benefits of GLP-1 analogues : evidence and implications for type 2 diabetes management

  2020cites this paper
• Recent efforts in drug discovery on vascular inflammation and consequent atherosclerosis

  2020influential citation
• New molecular biomarkers in precise diagnosis and therapy of Type 2 diabetes

  2020cites this paper
• Endothelial Dysfunction and Thrombosis in Patients With COVID-19—Brief Report

  2020cites this paper
• Canagliflozin impedes ischemic hind-limb recovery in the setting of diabetes

  2020cites this paper
• Weight reduction ameliorates inflammatory cytokines, adipocytokines and endothelial dysfunction biomarkers among Saudi patients with type 2 diabetes

  2020cites this paper
• Vascular Protection by Exercise in Obesity: Inflammasome-associated Mechanisms

  2020cites this paper
• Plant compounds for the treatment of diabetes, a metabolic disorder: NF-κB as therapeutic target.

  2020cites this paper