Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Cancer Research

• Publication date

  2002-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 12235002
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000influential reference
• Chemosensitisation of malignant melanoma by BCL2 antisense therapy.

  2000influential reference
• Angiogenesis in cancer and other diseases

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• Vascular-specific growth factors and blood vessel formation

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• ECM signalling: orchestrating cell behaviour and misbehaviour.

  1998cited by this paper
• bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

  1998influential reference
• Tumor induction of VEGF promoter activity in stromal cells.

  1998cited by this paper
• Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis.

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• ECM and Cell Surface Proteolysis: Minireview Regulating Cellular Ecology

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• ECM and cell surface proteolysis: regulating cellular ecology.

  1997cited by this paper
• Translating genomics information into therapeutics: A key role for oligonucleotides

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  1994cited by this paper
• Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse.

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  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1987cited by this paper
• Regulation of colony-stimulating factor 1 during pregnancy

  1986cited by this paper
• The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1.

  1985cited by this paper
• The multistep nature of cancer development.

  1984cited by this paper
• CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

  1983cited by this paper
• Metastatic potential correlates with enzymatic degradation of basement membrane collagen

  1980influential reference
• Activated macrophages induce vascular proliferation

  1977cited by this paper
• Antisense Oligonucleotides as Therapeutic Agents Is the Bullet Really Magical ?

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