Vitronectin is expressed in the ventral region of the neural tube and promotes the differentiation of motor neurons.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Development

• Publication date

  1997-12-15

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 9362471
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Textura del Sistema Nervioso del Hombre y de los Vertebrados, 1899–1904

  2019cited by this paper
• A series of normal stages in the development of the chick embryo. 1951.

  2012cited by this paper
• Pintallavis , a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis

  1999cited by this paper
• Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation.

  1996cited by this paper
• Laminin-1 selectively stimulates neuron generation from cultured retinal neuroepithelial cells.

  1996cited by this paper
• Vertebrate neural progenitor cells: subtypes and regulation.

  1996cited by this paper
• Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity.

  1996influential reference
• Developmentally regulated vitronectin influences cell differentiation, neuron survival and process outgrowth in the developing chicken retina.

  1995cited by this paper
• Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

  1995cited by this paper
• Control of epithelial morphogenesis by cell signaling and integrin molecules in the Drosophila foregut.

  1995cited by this paper
• Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo.

  1995cited by this paper
• The long and short of hedgehog signaling.

  1995cited by this paper
• Induction of midbrain dopaminergic neurons by Sonic hedgehog.

  1995cited by this paper
• Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm.

  1995cited by this paper
• Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation.

  1995cited by this paper
• Sonic hedgehog induces the differentiation of ventral forebrain neurons: a common signal for ventral patterning within the neural tube.

  1995cited by this paper
• Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis.

  1995cited by this paper
• Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube.

  1995cited by this paper
• Proteolytic processing yields two secreted forms of sonic hedgehog

  1995cited by this paper
• Vitronectin is not essential for normal mammalian development and fertility.

  1995cited by this paper
• Early stages of notochord and floor plate development in the chick embryo defined by normal and induced expression of HNF-3 beta.

  1995cited by this paper
• The role of the notochord and floor plate in inductive interactions.

  1995cited by this paper
• Distribution of vitronectin mRNA during murine development

  1995cited by this paper
• Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes.

  1994cited by this paper
• The tenascin gene family.

  1994cited by this paper
• αv Integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development

  1994cited by this paper
• Differentiation, extracellular matrix synthesis, and integrin assembly by Drosophila embryo cells cultured on vitronectin and laminin substrates

  1994cited by this paper
• Functional role of cytotactin/tenascin in morphogenesis: a modest proposal.

  1994cited by this paper
• Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.

  1994cited by this paper
• Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain.

  1994cited by this paper
• Alpha v integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development.

  1994cited by this paper
• Vitronectin and its receptors.

  1993cited by this paper
• A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos.

  1993cited by this paper
• Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.

  1993cited by this paper
• A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

  1993cited by this paper
• Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate.

  1993cited by this paper
• Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord.

  1993influential reference
• Gene knockouts of c-src, transforming growth factor beta 1, and tenascin suggest superfluous, nonfunctional expression of proteins

  1993cited by this paper
• Signal transduction from the extracellular matrix

  1993cited by this paper
• Regulation of development and differentiation by the extracellular matrix.

  1993cited by this paper
• Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis.

  1992cited by this paper
• Mice develop normally without tenascin.

  1992cited by this paper
• Vitronectin diversity in evolution but uniformity in ligand binding and size of the core polypeptide.

  1992cited by this paper
• P-domains as shuffled cysteine-rich modules in integumentary mucin C.1 (FIM-C.1) from Xenopus laevis. Polydispersity and genetic polymorphism.

  1992cited by this paper
• Drosophila PS2 integrin mediates RGD-dependent cell-matrix interactions.

  1992cited by this paper
• Integrins: versatility, modulation, and signaling in cell adhesion.

  1992cited by this paper
• Type XIV collagen is a variant of undulin.

  1992cited by this paper
• Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis.

  1992cited by this paper
• The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.

  1991cited by this paper
• Structure and biological role of vitronectin.

  1991influential reference
• Drosophila PS integrins recognize vertebrate vitronectin and function as cell-substratum adhesion receptors in vitro.

  1991cited by this paper
• Vitronectin and thrombospondin promote retinal neurite outgrowth: developmental regulation and role of integrins.

  1991cited by this paper
• Lineage analysis with a recombinant retrovirus: application to chick spinal motor neurons.

  1991cited by this paper
• Extracellular matrix molecules and their receptors: functions in neural development.

  1991cited by this paper
• A widely distributed antigen developmentally regulated in the nervous system.

  1990cited by this paper
• Monoclonal antibody EMR1a/212D recognizing site of deposition of extracellular lipid in atherosclerosis. Isolation and characterization of a cDNA clone for the antigen.

  1990cited by this paper
• Diversities in animal vitronectins. Differences in molecular weight, immunoreactivity and carbohydrate chains.

  1990cited by this paper
• Embryonic neural retinal cell response to extracellular matrix proteins: developmental changes and effects of the cell substratum attachment antibody (CSAT)

  1987cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• The development of the rat spinal cord.

  1984cited by this paper
• Developmental changes in unique cell surface antigens of chick embryo spinal motoneurons and ganglion cells.

  1984cited by this paper
• Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle.

  1983cited by this paper
• Serum spreading factor (vitronectin) is present at the cell surface and in tissues.

  1983cited by this paper
• DNA sequences, gene regulation and modular protein evolution in the Drosophila 68C glue gene cluster.

  1983influential reference
• Growth of a rat neuroblastoma cell line in serum-free supplemented medium.

  1979cited by this paper
• A series of normal stages in the development of the chick embryo

  1951cited by this paper

• Primary cilia are required for cell-type determination and angiogenesis in the pituitary development.

  2024cites this paper
• Role of Vitronectin and Its Receptors in Neuronal Function and Neurodegenerative Diseases

  2022cites this paper
• Vitronectin regulates the axon specification of mouse cerebellar granule cell precursors via αvβ5 integrin in the differentiation stage.

  2021cites this paper
• Vitronectin is Involved in the Morphological Transition of Neurites in Retinoic Acid-Induced Neurogenesis of Neuroblastoma Cell Line Neuro2a

  2019cites this paper
• αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors.

  2018cites this paper
• Vitronectin Regulates the Fibrinolytic System during the Repair of Cerebral Cortex in Stab-Wounded Mice

  2017cites this paper
• Vitronectin promotes the progress of the initial differentiation stage in cerebellar granule cells.

  2016cites this paper
• Nanofibrous Hydrogels with Spatially Patterned Biochemical Signals to Control Cell Behavior

  2015cites this paper
• The notochord: structure and functions

  2015cites this paper
• Engineering extracellular matrix signals into fibrous hyaluronic acid hydrogels

  2015cites this paper
• Lessons from the Embryonic Neural Stem Cell Niche for Neural Lineage Differentiation of Pluripotent Stem Cells

  2012cites this paper
• The extracellular matrix molecule tenascin C modulates expression levels and territories of key patterning genes during spinal cord astrocyte specification

  2011cites this paper
• Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.

  2011cites this paper
• Characterization of a human fetal spinal cord stem cell line, NSI‐566RSC, and its induction to functional motoneurons

  2010cites this paper
• Cell adhesion glycoprotein vitronectin during Xenopus laevis embryogenesis.

  2010cites this paper
• Developmental expression of prion protein and its ligands stress‐inducible protein 1 and vitronectin

  2009cites this paper
• Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells

  2009cites this paper
• The bladder extracellular matrix. Part I: architecture, development and disease

  2009cites this paper
• Expression and Purification of the Central Domain from Vitronectin

  2008cites this paper
• The vitronectin gene in rainbow trout: cloning, expression and phylogenetic analysis.

  2008cites this paper
• Cellular prion protein interaction with vitronectin supports axonal growth and is compensated by integrins

  2007cites this paper
• Signal dynamics in Sonic hedgehog tissue patterning

  2006cites this paper
• Vitronectin and Plasminogen Activator Inhibitor-1 Form Higher-Order Complexes that Localize to the Extracellular Matrix and Adopt Adhesive Properties

  2006cites this paper
• Poliovirus, pathogenesis of poliomyelitis, and apoptosis.

  2005cites this paper
• Differentiation of the vertebrate retina is coordinated by an FGF signaling center.

  2005cites this paper
• Genes controlling zebrafish development: Roles for Rabs and Glis.

  2004cites this paper
• Poliovirus and apoptosis.

  2004cites this paper
• Gene expression and regulation of hindbrain and spinal cord development.

  2004cites this paper
• Regulation of an inactivating potassium current (IA) by the extracellular matrix protein vitronectin in embryonic mouse hippocampal neurones

  2003cites this paper
• Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification.

  2003cites this paper
• Poliovirus-Induced Apoptosis Is Reduced in Cells Expressing a Mutant CD155 Selected during Persistent Poliovirus Infection in Neuroblastoma Cells

  2003cites this paper
• Developmental roles and clinical significance of hedgehog signaling.

  2003cites this paper
• Cell-type dependency of two Foxa/HNF3 sites in the regulation of vitronectin promoter activity.

  2002cites this paper
• Foxa (HNF3) up-regulates vitronectin expression during retinoic acid-induced differentiation in mouse neuroblastoma Neuro2a cells.

  2002influential citation
• Expression of the Human Poliovirus Receptor/CD155 Gene Is Activated by Sonic Hedgehog*

  2002cites this paper
• Caught in the matrix : how vitronectin controls neuronal differentiation

  2001cites this paper
• Identification of sonic hedgehog-responsive genes using cDNA microarray.

  2001cites this paper
• Substrate-bound human recombinant L1 selectively promotes neuronal attachment and outgrowth in the presence of astrocytes and fibroblasts.

  2001cites this paper
• Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation.

  2001cites this paper
• The poliovirus receptor CD155 mediates cell-to-matrix contacts by specifically binding to vitronectin.

  2001cites this paper
• Caught in the matrix: how vitronectin controls neuronal differentiation

  2001cites this paper
• Caught in the matrix: how vitronectin controls neuronal differentiation.

  2001cites this paper
• A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

  2001cites this paper
• Morphogenesis of neuron systems in tissue culture repeats evolutionarily simple nervous systems

  2000cites this paper
• Control of Shh activity and signaling in the neural tube

  2000cites this paper
• Development of specific connectivity between premotor neurons and motoneurons in the brain stem and spinal cord.

  2000cites this paper
• Gliogenesis in the central nervous system

  2000cites this paper
• Synaptic control of motoneuronal excitability.

  2000cites this paper
• Diverse mechanisms of osteoblast spreading on hydroxyapatite and titanium.

  2000cites this paper
• Sonic hedgehog synergizes with the extracellular matrix protein vitronectin to induce spinal motor neuron differentiation.

  2000influential citation
• Control of Shh activity and signaling in the neural tube.

  2000cites this paper
• COUP-TFI (chicken ovalbumin upstream promoter-transcription factor I) regulates cell migration and axogenesis in differentiating P19 embryonal carcinoma cells.

  2000cites this paper
• Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites.

  2000cites this paper
• The role of Sonic hedgehog in neural tube patterning

  2000cites this paper
• Patterning motoneurons in the vertebrate nervous system.

  1999cites this paper
• Identification of vitronectin as a novel insulin-like growth factor-II binding protein.

  1999cites this paper
• Neurogenesis in the developing neural tube

  1999cites this paper
• Sonic hedgehog (SHH) specifies muscle pattern at tissue and cellular chick level, in the chick limb bud.

  1999cites this paper
• Genetic and molecular analyses of motoneuron development.

  1998cites this paper
• Spinal Cord Neuronal Precursors Generate Multiple Neuronal Phenotypes in Culture

  1998cites this paper