Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Nature

• Publication date

  1995-05-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/375322A0PMID 7753196
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A series of normal stages in the development of the chick embryo. 1951.

  2012cited by this paper
• The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

  1995cited by this paper
• Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing.

  1995cited by this paper
• Control of neuronal diversity by the floor plate: contact-mediated induction of midbrain dopaminergic neurons.

  1995cited by this paper
• Proteolytic processing yields two secreted forms of sonic hedgehog

  1995cited by this paper
• Drosophila hedgehog acts as a morphogen in cellular patterning.

  1994cited by this paper
• Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs

  1994cited by this paper
• Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

  1994cited by this paper
• Products, genetic linkage and limb patterning activity of a murine hedgehog gene.

  1994cited by this paper
• Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes.

  1994cited by this paper
• The hedgehog gene family in Drosophila and vertebrate development.

  1994cited by this paper
• Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs.

  1994cited by this paper
• Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.

  1994cited by this paper
• Autoproteolysis in hedgehog protein biogenesis.

  1994cited by this paper
• The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye.

  1993cited by this paper
• A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos.

  1993cited by this paper
• Sonic hedgehog mediates the polarizing activity of the ZPA.

  1993cited by this paper
• Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.

  1993cited by this paper
• Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo

  1993cited by this paper
• Dorso-ventral patterning in the neural tube.

  1993cited by this paper
• Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate.

  1993cited by this paper
• Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.

  1992cited by this paper
• Controlling basal expression in an inducible T7 expression system by blocking the target T7 promoter with lac repressor.

  1991cited by this paper
• Control of cell pattern in the developing nervous system: polarizing activity of the floor plate and notochord.

  1991cited by this paper
• The homeodomain LIM protein Isl-1 is expressed in subsets of neurons and endocrine cells in the adult rat.

  1991cited by this paper
• Requirements for hedgehog, a segmental polarity gene, in patterning larval and adult cuticle of Drosophila.

  1988cited by this paper
• Developmental changes in unique cell surface antigens of chick embryo spinal motoneurons and ganglion cells.

  1984cited by this paper
• A series of normal stages in the development of the chick embryo

  1951cited by this paper

• Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

  2026cites this paper
• Early spinal cord development: from neural tube formation to neurogenesis

  2025cites this paper
• Shh signaling directs dorsal ventral patterning in the regenerating X. tropicalis spinal cord.

  2025cites this paper
• Coordinating tissue development to build body and brain: Lessons from the gastrula organiser and its derivatives.

  2025cites this paper
• A perfect islet: reviewing recent protocol developments and proposing strategies for stem cell derived functional pancreatic islets

  2025cites this paper
• scRNA-seq analysis of cells comprising the amphioxus notochord.

  2024cites this paper
• Shh signaling directs dorsal ventral patterning in the regenerating X. tropicalis spinal cord

  2024cites this paper
• Organizing activities of axial mesoderm.

  2024cites this paper
• Design of neural organoids engineered by mechanical forces

  2024cites this paper
• From signalling to form: the coordination of neural tube patterning.

  2024cites this paper
• Cell mechanics in early vertebrate development: Yap mechanotransduction controls notochord formation and neural tube patterning

  2023cites this paper
• The Potential Therapeutic Application of Simvastatin for Brain Complications and Mechanisms of Action

  2023cites this paper
• Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression

  2023cites this paper
• An in vivo drug screen in zebrafish reveals that cyclooxygenase 2‐derived prostaglandin D2 promotes spinal cord neurogenesis

  2023cites this paper
• Constitutive and conditional gene knockout mice for the study of intervertebral disc degeneration: Current status, decision considerations, and future possibilities

  2023cites this paper
• Concurrent temporal patterning of neural stem cells in the fly visual system

  2022cites this paper
• Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals

  2022cites this paper
• Generating neural diversity through spatial and temporal patterning.

  2022cites this paper
• Early development of the breathing network.

  2022cites this paper
• Transcription factors regulating the specification of brainstem respiratory neurons

  2022cites this paper
• Is There a Prechordal Region and an Acroterminal Domain in Amphioxus?

  2022cites this paper
• Single Transcription Factor-Based Differentiation Allowing Fast and Efficient Oligodendrocyte Generation via SOX10 Overexpression.

  2021cites this paper
• Non-Syndromic Intellectual Disability and Its Pathways: A Long Noncoding RNA Perspective

  2021cites this paper
• Expression of the hippocampal PTCH during early abstinence is associated with drinking patterns in a rat model of voluntary alcohol intake

  2021cites this paper
• Role of SHH in Patterning Human Pluripotent Cells towards Ventral Forebrain Fates

  2021cites this paper
• Stem Cell Neurodevelopmental Solutions for Restorative Treatments of the Human Trunk and Spine

  2021cites this paper
• Human neural organoids: Models for developmental neurobiology and disease.

  2021cites this paper
• Development of the central nervous system

  2021cites this paper
• The Pleiotropic Intricacies of Hedgehog Signaling: From Craniofacial Patterning to Carcinogenesis

  2021cites this paper
• Temporal single-cell transcriptomes of zebrafish spinal cord pMN progenitors reveal distinct neuronal and glial progenitor populations

  2021cites this paper
• Neural induction: Historical views and application to pluripotent stem cells

  2020cites this paper
• Investigating the role of ZEB2 in the establishment of neuroepithelial architecture and axon tract formation

  2020cites this paper
• Developmental Genes and Malformations in the Hypothalamus

  2020cites this paper
• Development of the locomotor system—Chick embryo

  2020cites this paper
• The role of Shh signalling pathway in central nervous system development and related diseases

  2020cites this paper
• Transcriptome profiles of sturgeon lateral line electroreceptor and mechanoreceptor during regeneration

  2020cites this paper
• Effect of sonic hedgehog on motor neuron positioning in the spinal cord during chicken embryonic development

  2019cites this paper
• SHH signaling mediated by a prechordal and brain enhancer controls forebrain organization

  2019cites this paper
• Establishing neuronal diversity in the spinal cord: a time and a place

  2019cites this paper
• Distinct temporal requirements for Sonic hedgehog signaling in development of the tuberal hypothalamus

  2018influential citation
• Gene-environment interactions in the causation and prevention of neural tube defects

  2018influential citation
• A Scube2-Shh feedback loop links morphogen release and spread to morphogen signaling to enable scale invariant patterning of the ventral neural tube

  2018cites this paper
• Dynarrestin, a Novel Inhibitor of Cytoplasmic Dynein.

  2018influential citation
• The role of Schwann cell c-Jun in restoring axon regeneration deficits in the peripheral nervous system

  2018cites this paper
• Sonic Hedgehog Regulation of the Neural Precursor Cell Fate During Chicken Optic Tectum Development

  2018cites this paper
• - 08-07 Hedgehog Signaling in Cancer

  2018cites this paper
• Sonic hedgehog protects endometrial hyperplasial cells against oxidative stress via suppressing mitochondrial fission protein dynamin‐like GTPase (Drp1)☆

  2018cites this paper
• Histology Atlas of the Developing Prenatal and Postnatal Mouse Central Nervous System, with Emphasis on Prenatal Days E7.5 to E18.5

  2017cites this paper
• The effect of sonic hedgehog on motor neuron positioning in the spinal cord during chicken embryo development

  2017cites this paper
• IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture

  2017cites this paper
• Novel Mechanisms that Antagonize Hedgehog Signaling at the Cell Surface During Vertebrate Embryogenesis

  2017influential citation
• Membrane-bound full-length Sonic Hedgehog identifies cancer stem cells in human non-small cell lung cancer

  2017cites this paper
• Targeting sonic hedgehog signaling in neurological disorders

  2017cites this paper
• Morphogen interpretation: concentration, time, competence, and signaling dynamics

  2017cites this paper
• IFT 56 regulates vertebrate developmental patterning by maintaining IFTB integrity and ciliary microtubule architecture

  2017cites this paper
• Development of the hypothalamus: conservation, modification and innovation

  2017influential citation
• Shh-mediated centrosomal recruitment of PKA promotes symmetric proliferative neuroepithelial cell division

  2017cites this paper
• The effect of sonic hedgehog on motor neuron positioning in the 1 spinal cord during chicken embryo development

  2017cites this paper
• FORMATION OF THREE DIMIENSIONAL CARTILAGE MATRICES

  2017cites this paper
• Microfluidics and imaging techniques for high-throughput studies of early embryonic development

  2016cites this paper
• Efficient derivation of dopaminergic neurons from SOX1− floor plate cells under defined culture conditions

  2016cites this paper
• Two Stories of Neurodevelopment: Exosome-Mediated Secretion of Sonic Hedgehog and Somatic Mutation in Disorders of DNA Damage Repair

  2016cites this paper
• Title Efficient derivation of dopaminergic neurons from SOX 1 (-) floorplate cells under defined culture conditions

  2016cites this paper
• Mécanismes cellulaires et moléculaires régulés par SLITRK2 et SLITRK5 dans la formation des circuits dopaminergiques du mésencéphale

  2016cites this paper
• Gene regulation in the ventral midbrain of the developing chick embryo

  2016cites this paper
• Hedgehog Signaling Modulates the Release of Gliotransmitters from Cultured Cerebellar Astrocytes

  2016cites this paper
• Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function

  2015cites this paper
• Notochord manipulation does not impact oesophageal and tracheal formation from isolated foregut in 3D explant culture

  2015cites this paper
• Hedgehog Acyltransferase as a target in estrogen receptor positive, HER2 amplified, and tamoxifen resistant breast cancer cells

  2015cites this paper
• Desert and Sonic Hedgehog Signalling in T cell Differentiation

  2015cites this paper
• Nanotissue Engineering of Neural Cells

  2015cites this paper
• Generating Diverse Spinal Motor Neuron Subtypes from Human Pluripotent Stem Cells

  2015cites this paper
• A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo

  2015cites this paper
• Ciliary adenylyl cyclases control the Hedgehog pathway

  2015cites this paper
• An emerging role for prdm family genes in dorsoventral patterning of the vertebrate nervous system

  2015cites this paper
• Sonic hedgehog processing and release are regulated by glypican heparan sulfate proteoglycans

  2015cites this paper
• Sonic hedgehog processing and release are regulated by glypican heparan sulfate proteoglycans

  2015cites this paper
• Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties.

  2015cites this paper
• A conserved role for Notch in priming the cellular response to Shh through ciliary localisation of the key Shh transducer , Smoothened

  2015influential citation
• How to make a midbrain dopaminergic neuron

  2015cites this paper
• Sonic hedgehog overexpression regulates the neuroepithelial cells proliferation in the spinal cord of dorsal regions during chicken embryo development.

  2015cites this paper
• Design and characterization of a photo-activatable hedgehog probe that mimics the natural lipidated form.

  2015cites this paper
• Optochemical dissection of T-box gene-dependent medial floor plate development.

  2015cites this paper
• Morphogen rules: design principles of gradient-mediated embryo patterning

  2015cites this paper
• Methods affecting neuronal differentiation of human adult and pluripotent stem cells

  2015cites this paper
• Identification of TULP3 as a negative regulator of Hedgehog signalling in the mouse

  2015cites this paper
• Investigation of the SHH gradient during limb development through quantitation of transcriptional regulation, expression, and protein distribution.

  2015influential citation
• Secreted HHIP 1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function

  2015cites this paper
• Hedgehog Signaling in Cancer

  2015cites this paper
• Motor neurons and the generation of spinal motor neuron diversity

  2014cites this paper
• An Epigenetic Biomarker Panel for Glioblastoma Multiforme Personalized Medicine through DNA Methylation Analysis of Human Embryonic Stem Cell-like Signature

  2014influential citation
• Transcription Factor‐Induced Lineage Programming of Noradrenaline and Motor Neurons from Embryonic Stem Cells

  2014cites this paper
• Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland.

  2014cites this paper
• Sonic hedgehog signalling pathway: a complex network

  2014cites this paper
• Geminin loss causes neural tube defects through disrupted progenitor specification and neuronal differentiation.

  2014cites this paper
• Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cord

  2014cites this paper
• T-cell TGF-β signaling abrogation restricts medulloblastoma progression

  2014cites this paper
• Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells

  2014cites this paper
• Ocular involvement in fetal alcohol spectrum disorder: a review.

  2014cites this paper
• Lentivirus-mediated delivery of sonic hedgehog into the striatum stimulates neuroregeneration in a rat model of Parkinson disease

  2014cites this paper