Hedgehog signaling via angiopoietin1 is required for developmental vascular stability.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Mechanisms of Development

• Publication date

  2010-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.mod.2010.02.001PMID 20156556
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of vascular mural cells during zebrafish development.

  2009cited by this paper
• olig1 expression identifies developing oligodendrocytes in zebrafish and requires hedgehog and notch signaling

  2009cited by this paper
• The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation

  2009cited by this paper
• Sonic hedgehog is required for the assembly and remodeling of branchial arch blood vessels

  2008cited by this paper
• FoxH1 negatively modulates flk1 gene expression and vascular formation in zebrafish.

  2007cited by this paper
• Compensatory signalling induced in the yolk sac vasculature by deletion of TGFβ receptors in mice

  2007cited by this paper
• The Tol2kit: A multisite gateway‐based construction kit for Tol2 transposon transgenesis constructs

  2007cited by this paper
• Sonic hedgehog inversely regulates the expression of angiopoietin-1 and angiopoietin-2 in fibroblasts.

  2007cited by this paper
• Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling.

  2006cited by this paper
• Faculty Opinions recommendation of The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling.

  2006cited by this paper
• Angiogenesis within the developing mouse neural tube is dependent on sonic hedgehog signaling: possible roles of motor neurons

  2005cited by this paper
• Craniofacial Anomalies of the Cultured Mouse Embryo Induced by Inhibition of Sonic Hedgehog Signaling: An Animal Model of Holoprosencephaly

  2005cited by this paper
• Angiopoietin 1 causes vessel enlargement, without angiogenic sprouting, during a critical developmental period

  2005cited by this paper
• Notch3 is required for arterial identity and maturation of vascular smooth muscle cells.

  2004cited by this paper
• iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo.

  2004cited by this paper
• The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling

  2004cited by this paper
• Notch 3 is required for arterial identity and maturation of vascular smooth muscle cells

  2004cited by this paper
• Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

  2004cited by this paper
• Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

  2002cited by this paper
• Hedgehog is required for murine yolk sac angiogenesis.

  2002cited by this paper
• Angiopoietin 2 stimulates migration and tube-like structure formation of murine brain capillary endothelial cells through c-Fes and c-Fyn.

  2002cited by this paper
• Defective Associations between Blood Vessels and Brain Parenchyma Lead to Cerebral Hemorrhage in Mice Lacking αv Integrins

  2002cited by this paper
• sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation.

  2002influential reference
• Isolation and expression analysis of three zebrafish angiopoietin genes

  2001cited by this paper
• The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

  2001cited by this paper
• Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2.

  2001cited by this paper
• Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway

  2000cited by this paper
• Developmental Biology of the Vascular Smooth Muscle Cell: Building a Multilayered Vessel Wall

  1999cited by this paper
• Cloning and characterization of vascular endothelial growth factor (VEGF) from zebrafish, Danio rerio.

  1998cited by this paper
• TIE1 and TIE2 receptor tyrosine kinases inversely regulate embryonic angiogenesis by the mechanism of intussusceptive microvascular growth.

  1998cited by this paper
• High-frequency generation of transgenic zebrafish which reliably express GFP in whole muscles or the whole body by using promoters of zebrafish origin.

  1997cited by this paper
• Pericyte loss and microaneurysm formation in PDGF-B-deficient mice.

  1997cited by this paper
• Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.

  1997influential reference
• Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.

  1996influential reference
• Mutations affecting somite formation and patterning in the zebrafish, Danio rerio.

  1996cited by this paper
• Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis.

  1996cited by this paper
• Blood vessel formation: what is its molecular basis?

  1996cited by this paper
• Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2.

  1996cited by this paper
• The zebrafish book : a guide for the laboratory use of zebrafish (Danio rerio)

  1995influential reference
• Stages of embryonic development of the zebrafish

  1995influential reference
• Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo.

  1994cited by this paper
• Whole-mount in situ hybridizations on zebrafish embryos using a mixture of digoxigenin- and fluorescein-labelled probes.

  1994cited by this paper
• Edinburgh Research Explorer Analysis of talpid3 and wild-type chicken embryos reveals roles for Hedgehog signalling in development of the limb bud vasculature

  year unknowncited by this paper

• Comparative Proteomic Analysis Reveals Altered Ciliary Proteins in Sickle Cell Disease.

  2025cites this paper
• Cd248a regulates pericyte development and viability in zebrafish

  2025cites this paper
• Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish.

  2024cites this paper
• Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish

  2023cites this paper
• Cilia proteins are biomarkers of altered flow in the vasculature

  2022cites this paper
• Endothelial cilia dysfunction in pathogenesis of hereditary hemorrhagic telangiectasia

  2022cites this paper
• A cilium-independent role for intraflagellar transport 88 in regulating angiogenesis.

  2021cites this paper
• Cells responding to hedgehog signaling contribute to the theca of ovarian follicles.

  2021cites this paper
• Cerebrovascular development: mechanisms and experimental approaches

  2021cites this paper
• Nanocomposite scaffolds for accelerating chronic wound healing by enhancing angiogenesis

  2021cites this paper
• Tek (Tie2) is not required for cardiovascular development in zebrafish

  2020cites this paper
• MicroRNA26 attenuates vascular smooth muscle maturation via endothelial BMP signalling

  2019cites this paper
• Primary cilia are present on endothelial cells of the hyaloid vasculature but are not required for the development of the blood-retinal barrier

  2019cites this paper
• Role of Hedgehog Signaling in Vasculature Development, Differentiation, and Maintenance

  2019cites this paper
• foxc1 is required for embryonic head vascular smooth muscle differentiation in zebrafish.

  2019cites this paper
• The role of endothelial cilia in postembryonic vascular development

  2019cites this paper
• Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish (Danio rerio)

  2018cites this paper
• Pericyte Biology in Zebrafish.

  2018cites this paper
• Morphogenesis and differentiation of embryonic vascular smooth muscle cells in zebrafish

  2018influential citation
• MicroRNA regulation of BMP signaling; cross-talk between endothelium and vascular smooth muscle cells

  2018cites this paper
• Dose dependent effects of cadmium on tumor angiogenesis

  2017cites this paper
• Ftr82 Is Critical for Vascular Patterning during Zebrafish Development

  2017cites this paper
• Coral-Derived Natural Marine Compound GB9 Impairs Vascular Development in Zebrafish

  2017cites this paper
• Mitotic control by mRNA splicing regulators ensures primary cilia formation

  2017cites this paper
• Patterning mechanisms of the sub-intestinal venous plexus in zebrafish.

  2016cites this paper
• Etiology of intracerebral hemorrhage (ICH): novel insights from Zebrafish embryos.

  2016cites this paper
• Expression change in Angiopoietin-1 underlies change in relative brain size in fish

  2015cites this paper
• Renin expression in developing zebrafish is associated with angiogenesis and requires the Notch pathway and endothelium.

  2015cites this paper
• Comparative analysis of genes regulated by Dzip1/iguana and hedgehog in zebrafish

  2015influential citation
• Endothelial cilia are essential for developmental vascular integrity in zebrafish.

  2015cites this paper
• An α-Smooth Muscle Actin (acta2/αsma) Zebrafish Transgenic Line Marking Vascular Mural Cells and Visceral Smooth Muscle Cells

  2014cites this paper
• Nuclear Receptor Subfamily 2 Group F Member 1a (nr2f1a) Is Required for Vascular Development in Zebrafish

  2014cites this paper
• Biological insight, high-throughput datasets and the nature of neuro-degenerative disorders.

  2013cites this paper
• Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish

  2012cites this paper
• The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β.

  2012cites this paper
• Characterization of the Arterial Adventitia as a Sonic Hedgehog Responsive Niche

  2012cites this paper
• Rare Copy Number Variations in Adults with Tetralogy of Fallot Implicate Novel Risk Gene Pathways

  2012cites this paper
• Overactivation of Hedgehog Signaling Alters Development of the Ovarian Vasculature in Mice1

  2012cites this paper
• Rôle de la protéine Sonic Hedgehog dans la migration des cellules musculaires lisses et le recrutement des cellules murales sur les néovaisseaux : implication dans l’action de PDGF BB

  2012cites this paper
• Zebrafish as a model for hemorrhagic stroke.

  2011cites this paper
• Pericytes: developmental, physiological, and pathological perspectives, problems, and promises.

  2011cites this paper
• Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease

  2011cites this paper
• Growth Factor Expression in Atherosclerosis and Gene Transfer for Therapeutic Angiogenesis

  2011cites this paper