This in vivo time-lapse imaging study in zebrafish reveals how changes to brain blood flow drive vessel pruning via endothelial cell migration, and how pruning leads to the simplification of the brain vasculature during development.
Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish
Qi Chen,Luan Jiang,Chun Xing Li,Dan Hu,Ji-wen Bu,D. Cai,Jiu-Lin Du
Published 2012 in PLoS Biology
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- Publication year
2012
- Venue
PLoS Biology
- Publication date
2012-08-01
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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