Pinoresinol–lariciresinol reductase gene expression and secoisolariciresinol diglucoside accumulation in developing flax (Linum usitatissimum) seeds

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Planta

• Publication date

  2006-05-31

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s00425-006-0308-yPMID 16794840
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Genetic analysis of seed coat development in Arabidopsis.

  2005influential reference
• Role of Mammalian Lignans in the Prevention and Treatment of Prostate Cancer

  2005cited by this paper
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  2003cited by this paper
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• Flax seed lignan in disease prevention and health promotion

  2003influential reference
• Identification and stereochemical characterization of lignans in flaxseed and pumpkin seeds.

  2003cited by this paper
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  2003influential reference
• Biosynthesis of podophyllotoxin in Linum album cell cultures

  2002cited by this paper
• PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences

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  2001influential reference
• Isolation of a flax pectin methylesterase promoter and its expression in transgenic tobacco.

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  2001influential reference
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  2000influential reference
• Early nuclear events in plant defence signalling: rapid gene activation by WRKY transcription factors

  1999cited by this paper
• Evolution of Plant Defense Mechanisms

  1999cited by this paper
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  1997cited by this paper
• Efficient PCR walking on plant genomic DNA

  1997influential reference
• TATA box and initiator functions in the accurate transcription of a plant minimal promoter in vitro.

  1995cited by this paper
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  1995cited by this paper
• A flower‐specific Myb protein activates transcription of phenylpropanoid biosynthetic genes.

  1994cited by this paper
• Isolation of plant DNA from fresh tissue

  1990cited by this paper
• An improved assay for β-glucuronidase in transformed cells: methanol almost completely suppresses a putative endogenous β-glucuronidase activity.

  1990cited by this paper
• GUS fusions: beta‐glucuronidase as a sensitive and versatile gene fusion marker in higher plants.

  1987cited by this paper
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  1962cited by this paper

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