Worldwide mycotoxins contamination has a significant impact on animal and human health, and leads to economic losses accounted for billions of dollars annually. Since the application of pre- and post- harvest strategies, including chemical or physical removal, are not sufficiently effective, biological transformation is considered the most promising yet challenging approach to reduce mycotoxins accumulation. Although several microorganisms were reported to degrade mycotoxins, only a few enzymes have been identified, purified and characterized for this activity. This review focuses on the biotransformation of mycotoxins performed with purified enzymes isolated from bacteria, fungi and plants, whose activity was validated in in vitro and in vivo assays, including patented ones and commercial preparations. Furthermore, we will present some applications for detoxifying enzymes in food, feed, biogas and biofuel industries, describing their limitation and potentialities.
Mycotoxin Biotransformation by Native and Commercial Enzymes: Present and Future Perspectives
M. Loi,F. Fanelli,V. C. Liuzzi,A. Logrieco,G. Mulè
Published 2017 in Toxins
ABSTRACT
PUBLICATION RECORD
- Publication year
2017
- Venue
Toxins
- Publication date
2017-03-24
- Fields of study
Biology, Medicine, Chemistry, Environmental Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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