Effects of Endogenous Oxytocin Receptor Signaling in Nucleus Tractus Solitarius on Satiation‐Mediated Feeding and Thermogenic Control in Male Rats

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Endocrinology

• Publication date

  2017-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1210/en.2017-00200PMID 28575174PMCID PMC5659667
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2016influential reference
• Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

  2016cited by this paper
• Oxytocin's inhibitory effect on food intake is stronger in obese than normal-weight men

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• Chronic oxytocin administration inhibits food intake, increases energy expenditure, and produces weight loss in fructose-fed obese rhesus monkeys.

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• Brown Adipose Tissue Has Sympathetic-Sensory Feedback Circuits

  2015cited by this paper
• Medial nucleus tractus solitarius oxytocin receptor signaling and food intake control: the role of gastrointestinal satiation signal processing.

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  2015cited by this paper
• Translational and therapeutic potential of oxytocin as an anti-obesity strategy: Insights from rodents, nonhuman primates and humans.

  2015cited by this paper
• Amylin Modulates the Mesolimbic Dopamine System to Control Energy Balance

  2015cited by this paper
• Oxytocin reduces caloric intake in men

  2015influential reference
• Control of Food Intake and Energy Expenditure by Nos1 Neurons of the Paraventricular Hypothalamus

  2014cited by this paper
• Leptin receptor signaling in the lateral parabrachial nucleus contributes to the control of food intake.

  2014cited by this paper
• Oxytocin in the ventromedial hypothalamic nucleus reduces feeding and acutely increases energy expenditure.

  2014cited by this paper
• Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcuate POMC neurons in hypothalamus

  2014cited by this paper
• Oxytocin receptor in the hypothalamus is sufficient to rescue normal thermoregulatory function in male oxytocin receptor knockout mice.

  2013cited by this paper
• Oxytocin Reduces Reward-Driven Food Intake in Humans

  2013cited by this paper
• A New Horizon: Oxytocin as a Novel Therapeutic Option for Obesity and Diabetes.

  2013influential reference
• Decreased intestinal nutrient response in diet-induced obese rats: role of gut peptides and nutrient receptors

  2013cited by this paper
• Oxytocin action in the ventral tegmental area affects sucrose intake.

  2013cited by this paper
• Vagal afferent fibres determine the oxytocin‐induced modulation of gastric tone

  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
• Differential Contribution of Hypothalamic MAPK Activity to Anxiety-Like Behaviour in Virgin and Lactating Rats

  2012influential reference
• Inactivation of Socs3 in the Hypothalamus Enhances the Hindbrain Response to Endogenous Satiety Signals via Oxytocin Signaling

  2012cited by this paper
• Ablation of Sim1 Neurons Causes Obesity through Hyperphagia and Reduced Energy Expenditure

  2012cited by this paper
• CCK-induced reduction of food intake and hindbrain MAPK signaling are mediated by NMDA receptor activation.

  2012influential reference
• An Obligate Role of Oxytocin Neurons in Diet Induced Energy Expenditure

  2012cited by this paper
• Reduction of food intake by cholecystokinin requires activation of hindbrain NMDA-type glutamate receptors.

  2011cited by this paper
• Circadian intervention of obesity development via resting-stage feeding manipulation or oxytocin treatment.

  2011cited by this paper
• Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation.

  2010cited by this paper
• Nutrient Specific Feeding and Endocrine Effects of Jejunal Infusions

  2010cited by this paper
• A new oxytocin-saporin cytotoxin for lesioning oxytocin-receptive neurons in the rat hindbrain.

  2010cited by this paper
• Mediobasal Hypothalamic Leucine Sensing Regulates Food Intake through Activation of a Hypothalamus–Brainstem Circuit

  2009cited by this paper
• New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behaviour and control of energy balance.

  2008cited by this paper
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  2008cited by this paper
• Oxytocin Enhances Cranial Visceral Afferent Synaptic Transmission to the Solitary Tract Nucleus

  2008cited by this paper
• Oxytocin receptor-deficient mice developed late-onset obesity

  2008cited by this paper
• Energetic responses are triggered by caudal brainstem melanocortin receptor stimulation and mediated by local sympathetic effector circuits.

  2008cited by this paper
• Vasopressin Inhibits Glutamate Release via Two Distinct Modes in the Brainstem

  2006cited by this paper
• Evidence that paraventricular nucleus oxytocin neurons link hypothalamic leptin action to caudal brain stem nuclei controlling meal size.

  2004cited by this paper
• Elevated plasma cholecystokinin and appetitive ratings after consumption of a liquid meal in humans.

  2003cited by this paper
• Oxytocin innervation of caudal brainstem nuclei activated by cholecystokinin.

  2003cited by this paper
• The oxytocin receptor system: structure, function, and regulation.

  2001cited by this paper
• Oxytocinergic inputs to the nucleus of the solitary tract and dorsal motor nucleus of the vagus in neonatal rats

  1998cited by this paper
• d-fenfluramine anorexia: dissociation of ingestion rate, meal duration, and meal size effects.

  1997cited by this paper
• The direct and indirect controls of meal size.

  1996cited by this paper
• Daily caloric intake in intact and chronic decerebrate rats.

  1993cited by this paper
• Enhanced social interactions in rats following chronic, centrally infused oxytocin.

  1992cited by this paper
• Gastric motility in conscious rats given oxytocin and an oxytocin antagonist centrally.

  1992cited by this paper
• Oxytocin, oxytocin antagonist, TRH, and hypothalamic paraventricular nucleus stimulation effects on gastric motility.

  1987cited by this paper
• Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction.

  1985cited by this paper
• Cholecystokinin persistently suppresses meal size but not food intake in free-feeding rats.

  1984cited by this paper
• Glucoreceptors controlling feeding and blood glucose: location in the hindbrain.

  1981cited by this paper
• Observations on the relationship between oxytocin and adrenaline in milk ejection in the sow.

  1952influential reference
• Printed in U.S.A. Copyright © 1997 by The Endocrine Society Central Oxytocin Administration Reduces Stress- Induced Corticosterone Release and Anxiety Behavior in Rats*

  year unknowninfluential reference

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• Vagal Oxytocin Receptors as Molecular Targets in Gut–Brain Signaling: Implications for Appetite, Satiety, Obesity, and Esophageal Motility—A Narrative Review

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• Oxytocin neurons in the paraventricular and supraoptic hypothalamic nuclei bidirectionally modulate food intake

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• Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of OT-elicited reductions of body weight gain and adiposity in male diet-induced obese rats

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• Viscerosensory signalling to the nucleus accumbens via the solitary tract nucleus

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• Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of oxytocin-elicited reductions of body weight and adiposity in male diet-induced obese mice

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• Neuroendocrine gut-brain signaling in obesity.

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• Systemic Co-Administration of Low-Dose Oxytocin and Glucagon-Like Peptide 1 Additively Decreases Food Intake and Body Weight

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• Hippocampus oxytocin signaling promotes prosocial eating in rats

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• Oxytocin increased intragastric pressure in the forestomach of rats via the dorsal vagal complex.

  2023cites this paper
• Modulation of the thermosensory system by oxytocin

  2023cites this paper
• Oxytocin as a potential pharmacological tool to combat obesity

  2022cites this paper
• Behavioral plasticity: Role of neuropeptides in shaping feeding responses.

  2022cites this paper
• Morpho-Electric Properties and Diversity of Oxytocin Neurons in Paraventricular Nucleus of Hypothalamus in Female and Male Mice

  2022cites this paper
• Oxytocin as an Anti-obesity Treatment

  2021cites this paper
• Chronic Hindbrain Administration of Oxytocin Elicits Weight Loss in Male Diet-Induced Obese Mice.

  2021cites this paper
• Central Neural Circuits Orchestrating Thermogenesis, Sleep-Wakefulness States and General Anesthesia States

  2021cites this paper
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  2021cites this paper
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• Oxytocin and Food Intake Control: Neural, Behavioral, and Signaling Mechanisms

  2021cites this paper
• Hindbrain Administration of Oxytocin Reduces Food Intake, Weight Gain and Activates Catecholamine Neurons in the Hindbrain Nucleus of the Solitary Tract in Rats

  2021cites this paper
• Oxytocin signaling in the posterior hypothalamus prevents hyperphagic obesity in mice

  2021cites this paper
• Peripheral insulin administration enhances the electrical activity of oxytocin and vasopressin neurones in vivo

  2020cites this paper
• NTS and VTA oxytocin reduces food motivation and food seeking.

  2020cites this paper
• The role of oxytocin in regulation of appetitive behaviour, body weight and glucose homeostasis

  2020cites this paper
• Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues in male rats

  2020cites this paper
• Sex Differences and Estrous Influences on Oxytocin Control of Food Intake.

  2019cites this paper
• Exposure to chlorpyrifos at different ages triggers APOE genotype-specific responses in social behavior, body weight and hypothalamic gene expression.

  2019cites this paper
• Long-Acting and Selective Oxytocin Peptide Analogs Show Antidiabetic and Antiobesity Effects in Male Mice

  2019cites this paper
• Convergent neuronal projections from paraventricular nucleus, parabrachial nucleus, and brainstem onto gastrocnemius muscle, white and brown adipose tissue in male rats

  2019cites this paper
• Oxytocin treatment reduced food intake and body fat and ameliorated obesity in ovariectomized female rats.

  2019cites this paper
• The relationship between oxytocin, dietary intake and feeding: A systematic review and meta-analysis of studies in mice and rats.

  2019cites this paper
• The osmoresponsiveness of oxytocin and vasopressin neurones: Mechanisms, allostasis and evolution

  2019cites this paper
• Metabolic Effects of Oxytocin.

  2019cites this paper
• The hypothalamus to brainstem circuit suppresses late-onset body weight gain

  2019cites this paper
• Oxytocin neurons: integrators of hypothalamic and brainstem circuits in the regulation of macronutrient-specific satiety

  2019cites this paper
• The Anorexigenic Neural Pathways of Oxytocin and Their Clinical Implication

  2018cites this paper
• Interplay between Oxytocin and Sensory Systems in the Orchestration of Socio-Emotional Behaviors.

  2018cites this paper
• Effects of Chronic Oxytocin Administration and Diet Composition on Oxytocin and Vasopressin 1a Receptor Binding in the Rat Brain.

  2018cites this paper
• MicroRNAs in the hypothalamic control of energy homeostasis

  2018cites this paper
• Central Oxytocin and Energy Balance: More Than Feelings.

  2017influential citation