Haplotypes of beta S chromosomes among patients with sickle cell anemia from Georgia.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Hemoglobin

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3109/03630268609036566PMID 2435679
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Association of the level of G gamma chain in the fetal hemoglobin of normal adults with specific haplotypes.

  1986cited by this paper
• Hematological observations on Arabian SS patients with a homozygosity or heterozygosity for a beta S chromosome with haplotype #31.

  1985cited by this paper
• Hematologically and genetically distinct forms of sickle cell anemia in Africa. The Senegal type and the Benin type.

  1985cited by this paper
• Common haplotype dependency of high G gamma-globin gene expression and high Hb F levels in beta-thalassemia and sickle cell anemia patients.

  1985cited by this paper
• A genetic marker for elevated levels of haemoglobin F in homozygous sickle cell disease?

  1985cited by this paper
• Five adults with mild sickle cell anemia share a βs chromosome with the same haplotype

  1985cited by this paper
• DNA sequence variation associated with elevated fetal G gamma globin production.

  1985cited by this paper
• The frequency of the gamma chain variant A gamma T in different populations, and its use in evaluating gamma gene expression in association with thalassemia.

  1985cited by this paper
• The rare alpha-thalassemia-1 of blacks is a zeta alpha-thalassemia-1 associated with deletion of all alpha- and zeta-globin genes

  1984cited by this paper
• The rare alpha-thalassemia-1 of blacks is a zeta alpha-thalassemia-1 associated with deletion of all alpha- and zeta-globin genes.

  1984cited by this paper
• Two novel arrangements of the human fetal globin genes: G gamma-G gamma and A gamma-A gamma.

  1984cited by this paper
• Heterogeneity in the molecular basis of three types of hereditary persistence of fetal hemoglobin and the relative synthesis of the G gamma and A gamma types of gamma chain.

  1984cited by this paper
• Two independent genetic factors in the beta-globin gene cluster are associated with high G gamma-levels in the HbF of SS patients.

  1984cited by this paper
• Evidence for the multicentric origin of the sickle cell hemoglobin gene in Africa.

  1984cited by this paper
• Origin of the beta S-globin gene in blacks: the contribution of recurrent mutation or gene conversion or both.

  1984cited by this paper
• The mutation and polymorphism of the human beta-globin gene and its surrounding DNA.

  1984cited by this paper
• Dutch beta 0-thalassaemia: a 10 kilobase DNA deletion associated with significant gamma-chain production.

  1984cited by this paper
• Two novel arrangements of the human fetal globin genes: Gγ-Gγ and Aγ-Aγ

  1984cited by this paper
• Dutch β°‐thalassaemia: a 10 kilobase DNA deletion associated with significant γ‐chain production

  1984cited by this paper
• High Performance Liquid Cbromatographic Separation of Globin Chains on a Large-Pore C4 Column

  1984cited by this paper
• Two independent genetic factors in the beta-globin gene cluster are associated with high G gamma-levels in the HbF of SS patients

  1984cited by this paper
• The occurrence of different levels of G gamma chain and of the A gamma T variant of fetal hemoglobin in newborn babies from several countries.

  1983cited by this paper
• The occurrence of different levels of Gγ chain and of the AγT variant of fetal hemoglobin in newborn babies from several countries

  1983cited by this paper
• A new high-performance liquid chromatographic procedure for the separation and quantitation of various hemoglobin variants in adults and newborn babies.

  1983cited by this paper
• Gamma thalassemia resulting from the deletion of a gamma-globin gene

  1983cited by this paper
• Construction of human gene libraries from small amounts of peripheral blood: analysis of beta-like globin genes.

  1982cited by this paper
• Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster.

  1982cited by this paper
• Concurrent sickle-cell anemia and alpha-thalassemia: effect on severity of anemia.

  1982cited by this paper
• The interaction of alpha-thalassemia and homozygous sickle-cell disease.

  1982cited by this paper
• Neonatal screening of β‐thalassemias by thin layer isoelectric focusing

  1982cited by this paper
• Concurrent Sickle-Cell Anemia and α-Thalassemia: Effect on Severity of Anemia

  1982cited by this paper
• The heterogeneity of the gamma-chain of fetal hemoglobin in HbS heterozygotes.

  1982cited by this paper
• Neonatal screening of beta-thalassemias by thin layer isoelectric focusing.

  1982cited by this paper
• Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

  1982cited by this paper
• Quantitation of three types of gamma chain of HbF by high pressure liquid chromatography; application of this method to the HbF of patients with sickle cell anemia or the S-HPFH condition.

  1981cited by this paper
• The Chromatography of Hemoglobin

  1980cited by this paper
• Human T gamma globin chain is a variant of A gamma chain (A gamma Sardinia).

  1979cited by this paper
• The chemical heterogeneity of human hemoglobin F: Direct evidence for the existence of three types of γ chain, the GγI, AγI, and AγT chains

  1979cited by this paper
• The chemical heterogeneity of human hemoglobin F. Direct evidence for the existence of three types of gamma chain, the G gamma I, A gamma I, and A gamma T chains.

  1979cited by this paper
• Further Nodification of the Mtcrochromatographic Deternination of Hemoglobin A

  1977cited by this paper
• The hemoglobinopathies: Techniques of identification

  1977cited by this paper
• Further modification of the microchromatographic determination of hemoglobin A2.

  1977cited by this paper
• A New Hb Variant: Hb F Sardinia γ75 (e 19) Isoieucine→Threonine Found in a Family with Hb G Philadelphia, β-Chain Deficiency and a Lepore-Like Haemoglobin Indistinguishable from Hb A2

  1975cited by this paper
• A new Hb variant: Hb F Sardinia gamma75(E19) isoleucine leads to threonine found in a family with Hb G Philadelphia, beta-chain deficiency and a Lepore-like haemoglobin indistinguishable from Hb A2.

  1975cited by this paper
• Evidence for multiple structural genes for the gamma chain of human fetal hemoglobin.

  1968cited by this paper
• Estimation of small percentages of foetal haemoglobin.

  1959cited by this paper
• Estimation of Small Percentages of Fœtal Hæmoglobin

  1959cited by this paper

• Microarray Technique for Studying Genetic Diversity in Saudi Sickle Cell Patients

  2022cites this paper
• Innovative Therapies for Hemoglobin Disorders

  2020cites this paper
• Manipulation of Developmental Gamma-Globin Gene Expression: an Approach for Healing Hemoglobinopathies

  2020cites this paper
• Genetic comparison of sickle cell anaemia cohorts from Brazil and the United States reveals high levels of divergence

  2019cites this paper
• Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding

  2018cites this paper
• Wake-up Sleepy Gene: Reactivating Fetal Globin for β-Hemoglobinopathies.

  2018cites this paper
• The origin of HTLV-1 in southern Bahia by phylogenetic, mtDNA and β-globin analysis

  2015cites this paper
• The origin of HTLV-1 in southern Bahia by b , go b , phylogenetic , mtDNA and β-globin analysis

  2015cites this paper
• HTLV EM GESTANTES DE DOIS MUNICÍPIOS DA REGIÃO SUL DA BAHIA E AVALIAÇÃO DA TRANSMISSÃO MATERNO-INFANTIL

  2014cites this paper
• Can STOP Trial Velocity Criteria Be Applied to Iranian Children with Sickle Cell Disease?

  2014influential citation
• Transcranial doppler ultrasonography in children with sickle cell anemia: Clinical and laboratory correlates for elevated blood flow velocities

  2014influential citation
• HTLV EM GESTANTES DE DOIS MUNICÍPIOS DA

  2014cites this paper
• Is Sickle Cell Trait a Risk Factor for Stroke and Cerebral Small Vessel Disease

  2014cites this paper
• Sickle cell anemia: clinical diversity and beta S-globin haplotypes

  2013cites this paper
• Characterization of Two Types of Fetal Hemoglobin: cy2'y2 and cy2*y2

  2013cites this paper
• probes identification of the types by hybridization of amplified DNA with synthetic Mild and severe beta-thalassemia among homozygotes from Turkey:

  2013cites this paper
• Acute chest syndrome is associated with single nucleotide polymorphism‐defined beta globin cluster haplotype in children with sickle cell anaemia

  2013cites this paper
• Identification and Reporting of Common Hemoglobin Disorders: A review

  2012cites this paper
• hemoglobin expression in human adults Upstream promoter mutation associated with a modest elevation of fetal

  2011cites this paper
• Micro-albuminuria in Ugandan children with sickle cell anaemia: a cross-sectional study

  2011cites this paper
• Importncia da avaliao da hemoglobina fetal na clnica da anemia falciforme

  2008cites this paper
• The importance of the evaluation of fetal hemoglobin in the clinical assessment of sickle cell disease

  2008cites this paper
• Confirmation of an Association Between the TNF(−308) Promoter Polymorphism and Stroke Risk in Children With Sickle Cell Anemia

  2007cites this paper
• Confirmation of an Association Between the TNF(−308) Promoter Polymorphism and Stroke Risk in Children With Sickle Cell Anemia

  2007cites this paper
• Developmental Effect of the XmnI Site on Gγ-Globin Gene Expression Among Newborn Hb F-Malta-I [Gγ117(G19)His→Arg, CAT→CGT] Heterozygotes and Adult β+-Thalassemia Homozygotes

  2007cites this paper
• Developmental effect of the XmnI site on Ggamma-globin gene expression among newborn Hb F-Malta-I [Ggamma117(G19)His-->Arg, CAT-->CGT] heterozygotes and adult beta+ -Thalassemia homozygotes.

  2007cites this paper
• G y and ly Globin Genes are Identical from -471 of the Promoter Midway through yIVSII in a Benin is Haplotype Associated with Elevated Fetal Hemoglobin

  2006cites this paper
• Predicting clinical severity in sickle cell anaemia

  2005cites this paper
• Clinical and Genetic Heterogeneity in Black Patients With Homozygous fi-Thalassemia From the Southeastern United States

  2005cites this paper
• Mortality in sickle cell patients on hydroxyurea therapy.

  2005cites this paper
• A Novel Approach to Rapid Determination of βS‐Globin Haplotypes: Sequencing of the Aγ‐IVS‐II Region

  2004cites this paper
• A novel approach to rapid determination of betaS-globin haplotypes: sequencing of the Agamma-IVS-II region.

  2004cites this paper
• Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen

  2003cites this paper
• Beta‐globin gene cluster haplotypes as evidence of African gene flow to the northeastern coast of Venezuela

  2003cites this paper
• Globin haplotypes of human T-cell lymphotropic virus type I-infected individuals in Salvador, Bahia, Brazil, suggest a post-Columbian African origin of this virus.

  2003cites this paper
• Characterization of β-globin haplotypes using blood spots from a population-based cohort of newborns with homozygous HbS

  2002cites this paper
• FORTY-FOUR YEARS (1955–1999) DEVOTED TO HEMOGLOBIN RESEARCH: TITUS H. J. HUISMAN (1923–1999)

  2001influential citation
• Evidence that microdeletions in the alpha globin gene protect against the development of sickle cell glomerulopathy in humans.

  1999cites this paper
• Comparison of the Relative Quantities of γ-mRNAs and Fetal Hemoglobin in SS Patients with Different Haplotypes

  1998cites this paper
• Hematological effects of atypical and cameroon β‐globin gene haplotypes in adult sickle cell anemia

  1998cites this paper
• Génétique des populations et histoire du peuplement de l'Afrique. Essai d'historiographie et d'épistémologie.

  1998cites this paper
• Hematological effects of atypical and Cameroon beta-globin gene haplotypes in adult sickle cell anemia.

  1998cites this paper
• Differential regulation of A gamma and G gamma fetal hemoglobin mRNA levels by hydroxyurea and butyrate.

  1998cites this paper
• Hydroxyurea therapy in sickle cell anemia patients in Curaçao, The Netherlands Antilles.

  1997cites this paper
• Hydroxyurea and Sickle Cell Anemia Clinical Utility of a Myelosuppressive “Switching” Agent

  1996cites this paper
• beta S haplotypes, alpha-globin gene status, and hematological data of sickle cell disease patients in Guadeloupe (F.W.I.).

  1996cites this paper
• βs Haplotypes, α-Globin Gene Status, and Hematological Data of Sickle Cell Disease Patients in Guadeloupe (F.W.I.)

  1996cites this paper
• Modulation of the phenotypic diversity of sickle cell anemia.

  1996cites this paper
• Frequency of haplotypes in the beta globin gene cluster in a selected sample of the mexican population

  1995cites this paper
• Genetic Modulation of Sickle Cell Anemia

  1995cites this paper
• Gender and haplotype effects upon hematological manifestations of adult sickle cell anemia

  1995cites this paper
• Fetal hemoglobin synthesis in sickle cell anemia: Some molecular considerations

  1994cites this paper
• The in vivo expression of the globin genes of theβ cistron in γ-,δ-, andδβ-thalassemia heterozygotes

  1994cites this paper
• Beta-S gene cluster haplotypes modulate hematologic and hemorheologic expression in sickle cell anemia. Use in predicting clinical severity.

  1994cites this paper
• Sickle cell disease in a Brazilian population from Sao Paulo: a study of the beta s haplotypes.

  1994cites this paper
• βS‐gene‐cluster haplotypes in sickle cell anemia patients from two regions of Brazil

  1994cites this paper
• The in vivo expression of the globin genes of the beta cistron in gamma-, delta-, and delta beta-thalassemia heterozygotes.

  1994cites this paper
• A novel deletion of approximately 27 kb including the beta-globin gene and the locus control region 3'HS-1 regulatory sequence: beta zero-thalassemia or hereditary persistence of fetal hemoglobin?

  1994cites this paper
• GγAγ(β+) hereditary persistence of fetal hemoglobin: The Gγ – 158 C → T mutation in cis to the − 175 T → C mutation of the Aγ‐globin gene results in increased Gγ‐globin synthesis

  1993cites this paper
• Sickle Cell Anemia: βs Gene Cluster Haplotypes as Genetic Markers for Severe Disease Expression

  1993cites this paper
• Multisystem damage associated with tricorporal priapism in sickle cell disease.

  1993cites this paper
• G gamma A gamma (beta+) hereditary persistence of fetal hemoglobin: the G gamma -158 C-->T mutation in cis to the -175 T-->C mutation of the A gamma-globin gene results in increased G gamma-globin synthesis.

  1993cites this paper
• Level of fetal hemoglobin in children with sickle cell anemia: influence of gender, haplotype and alpha-thalassemia-2 trait.

  1993cites this paper
• The structure and function of normal and abnormal haemoglobins.

  1993cites this paper
• Molecular characterisation of Vietnamese HPFH

  1993cites this paper
• Hb F in sickle cell anemia

  1993cites this paper
• Bantu βs cluster haplotype predominates among Brazilian Blacks

  1992cites this paper
• Haplotypes in SS patients from Nigeria; characterization of one atypical βS haplotype no. 19 (Benin) associated with elevated HB F and highGγ levels

  1992cites this paper
• β-Thalassemia Intermedia with Exceptionally High Hemoglobin A2: Relationship to Mutations in the β-Gene Promoter

  1992cites this paper
• Bantu beta s cluster haplotype predominates among Brazilian blacks.

  1992cites this paper
• Clinical, hematological, and molecular features in sicilians with Hb S‐β‐thalassemia

  1992cites this paper
• Clinical, hematological, and molecular features in Sicilians with Hb S-beta-thalassemia.

  1992cites this paper
• Sequence variations in the 5' hypersensitive site-2 of the locus control region of beta S chromosomes are associated with different levels of fetal globin in hemoglobin S homozygotes.

  1992cites this paper
• Black β‐thalassemia homozygotes with specific sequence variations in the 5′ hypersensitive site‐2 of the locus control region have high levels of fetal hemoglobin

  1992cites this paper
• Beta-thalassemia intermedia with exceptionally high hemoglobin A2: relationship to mutations in the beta-gene promoter.

  1992cites this paper
• Haplotypes in SS patients from Nigeria; characterization of one atypical beta S haplotype no. 19 (Benin) associated with elevated HB F and high G gamma levels.

  1992cites this paper
• βs Haplotypes in various world populations

  1992cites this paper
• Beta S haplotypes in various world populations.

  1992cites this paper
• Sickle cell anemia: beta s-gene-cluster haplotypes as prognostic indicators of vital organ failure.

  1991cites this paper
• Effect of beta-globin gene cluster haplotype on the hematological and clinical features of sickle cell anemia.

  1991cites this paper
• G gamma and A gamma globin genes are identical from -471 of the promoter midway through gamma IVSII in a Benin beta s haplotype associated with elevated fetal hemoglobin.

  1991cites this paper
• Sequence variations in the 5' flanking and IVS-II regions of the G gamma- and A gamma-globin genes of beta S chromosomes with five different haplotypes.

  1991cites this paper
• Sickle cell anemia in the Tunisian population: haplotyping and HB F expression.

  1991cites this paper
• The Xmn I site (-158, C----T) 5' to the G gamma gene: correlation with the Senegalese haplotype and G gamma globin expression.

  1991cites this paper
• Certain mutations observed in the 5' sequences of the G gamma- and A gamma-globin genes of beta S chromosomes are specific for chromosomes with major haplotypes.

  1991cites this paper
• Hb Mizuho or alpha 2 beta (2)68(E12)Leu----Pro in a Caucasian boy with high levels of Hb F; identification by sequencing of amplified DNA.

  1991cites this paper
• Effect of β‐Globin gene cluster haplotype on the hematological and clinical features of sickle cell anemia

  1991cites this paper
• Beta s-gene-cluster haplotypes in sickle cell anemia. Clinical and hematologic features.

  1991cites this paper
• Hemoglobinopathies Among the Gond Tribal Groups of Central India; Interaction of α- and β-Thalassemia with β Chain Variants

  1991cites this paper
• Hemoglobinopathies among the Gond tribal groups of central India; interaction of alpha- and beta-thalassemia with beta chain variants.

  1991cites this paper
• HB Mizuho or α2β268(E12)Leu→pro in a Caucasian Boy with high levels of HB F; Identification by Sequencing of Amplified DNA

  1991cites this paper
• Relationship of foetal haemoglobin levels and βs haplotypes in homozygous sickle cell disease

  1990cites this paper
• Beta S-gene-cluster haplotypes in sickle cell anemia: clinical implications.

  1990cites this paper
• Analysis of 5' flanking regions of the gamma globin genes from major African haplotype backgrounds associated with sickle cell disease.

  1990cites this paper
• Characterization of two types of fetal hemoglobin: alpha 2G gamma 2 and alpha 2A gamma 2.

  1990cites this paper
• The variable expression of sickle cell disease is genetically determined.

  1990cites this paper
• Sickle cell trait revisited.

  1989cites this paper
• The Influence of Fetal Hemoglobin on the Clinical Expression of Sickle Cell Anemia a

  1989cites this paper
• Homozygous beta-thalassemia without anemia.

  1989cites this paper
• Application of high-performance liquid chromatographic methodology to the analysis of hemoglobins synthesized in erythroid progenitor cells.

  1989cites this paper