Magnetic and Quantum Dot Nanoparticles for Drug Delivery and Diagnostic Systems

Nanoparticles are being used tremendously in biomedical sciences due to their promising chemical and physical properties. Magnetic nanoparticles and quantum dot nanocrystals are two of the main nanoparticle types used in the biomedical industry. The surface of these nanoparticles is further modified in order to obtain biocompatibility and surface functionalization. Magnetic properties, fluorescence, nanometer size, and availability of sites to modify its surface for bioconjugation provide greater potential to use these nanoparticles in targeted drug delivery technique and diagnostics. As a result, these nanoparticles create massive developments in the industrial operations. In this chapter, an overview of the nanoparticles used in drug delivery and diagnostic systems will be discussed. In addition, advantages in encapsulation of magnetic and quantum dot nanoparticles for bioconjugation and different methods of drug delivery will be addressed.

• Publication year

  2019

• Venue

  Colloid Science in Pharmaceutical Nanotechnology

• Publication date

  2019-12-17

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.5772/intechopen.88611
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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• Perspectives In Micro- And Nanotechnology For Biomedical Applications

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