Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation

The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil.

• Publication year

  2019

• Venue

  Brazilian Journal of Pharmaceutical Sciences

• Publication date

  Unknown publication date

• Fields of study

  Materials Science, Chemistry

• Identifiers
  DOI 10.1590/s2175-97902019000200261
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Alginate-based emulsion template containing high oil loading stabilized by nonionic surfactants.

  2015cited by this paper
• OPTIMIZATION AND CHARACTERIZATION OF CALCIUM ALGINATE/KONJAC GLUCOMANNAN BEADS AS ORAL PROTEIN DRUG DELIVERY SYSTEM

  2015cited by this paper
• Effect of ultrasonic treatment on extraction and fatty acid profile of flaxseed oil

  2015cited by this paper
• Optimization on the Stability of Linseed Oil-in-Water Nanoemulsions Generated by Ultrasonic Emulsification Using Response Surface Methodology (RSM)

  2015cited by this paper
• Alginate-pomegranate peels' polyphenols beads: effects of formulation parameters on loading efficiency

  2014influential reference
• Novel swellable polymer of orchidaceae family for gastroretentive drug delivery of famotidine

  2014cited by this paper
• Flax and flaxseed oil: an ancient medicine & modern functional food

  2014cited by this paper
• Encapsulation efficiency and oxidative stability of flaxseed oil microencapsulated by spray drying using different combinations of wall materials

  2013cited by this paper
• FORMULATION AND IN-VITRO RELEASE OF POMEGRANATE PEELS ’ POLYPHENOLS MICROBEADS

  2013cited by this paper
• Isolation, characterization and emulsion stabilizing properties of polysaccharides form orchid roots (salep)

  2012cited by this paper
• [Nutritional value and functional properties of flaxseed].

  2012cited by this paper
• Drug delivery using alginate and chitosan beads: An Overview

  2011cited by this paper
• Influence of emulsion composition and inlet air temperature on the microencapsulation of flaxseed oil by spray drying

  2011cited by this paper
• Preparation of Ca-alginate beads containing high oil content: Influence of process variables on encapsulation efficiency and bead properties

  2011influential reference
• N-3 Omega fatty acids: a review of current knowledge.

  2010cited by this paper
• Rheological characteristics of traditional salep drink flavored with cocoa powder.

  2010cited by this paper
• IONOTROPIC GELATION AND POLYELECTROLYTE COMPLEXATION : THE NOVEL TECHNIQUES TO DESIGN HYDROGEL PARTICULATE SUSTAINED , MODULATED DRUG DELIVERY SYSTEM : A REVIEW

  2010cited by this paper
• Effects of Two Emulsifiers on Yield and Storage of Flaxseed Oil Powder by Response Surface Methodology

  2009cited by this paper
• Flaxseed and Cardiovascular Health

  2009cited by this paper
• FORMULATION AND EVALUATION OF OIL ENTRAPPED FLOATING ALGINATE BEADS OF RANITIDINE HYDROCHLORIDE

  2009cited by this paper
• Prediction models for shape and size of ca-alginate macrobeads produced through extrusion-dripping method.

  2009cited by this paper
• Preparation of lactic acid bacteria-enclosing alginate beads in emulsion system: effect of preparation parameters on bead characteristics

  2009cited by this paper
• Fish oil encapsulation with chitosan using ultrasonic atomizer

  2008cited by this paper
• Microencapsulation of avocado oil by spray drying using whey protein and maltodextrin

  2008cited by this paper
• Effect of relative humidity on oxidation of flaxseed oil in spray dried whey protein emulsions.

  2008cited by this paper
• Dietary flaxseed inhibits atherosclerosis in the LDL receptor-deficient mouse in part through antiproliferative and anti-inflammatory actions.

  2007cited by this paper
• Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits.

  2006cited by this paper
• Maillard Reaction Products as Encapsulants for Fish Oil Powders

  2006cited by this paper
• Dietary flaxseed protects against ventricular fibrillation induced by ischemia-reperfusion in normal and hypercholesterolemic Rabbits.

  2004cited by this paper
• Oral colon-specific drug delivery for bee venom peptide: development of a coated calcium alginate gel beads-entrapped liposome.

  2003cited by this paper
• Pharmacokinetics of different routes of administration of misoprostol.

  2002cited by this paper
• Alginate-konjac glucomannan-chitosan beads as controlled release matrix.

  2002cited by this paper
• Preparation and in-vitro evaluation of alginate beads of flurbiprofen

  2002cited by this paper
• HYDROCOLLOIDS IN EMULSIONS: PARTICLE SIZE DISTRIBUTION AND INTERFACIAL ACTIVITY

  2001cited by this paper
• The effect of salep content on the rheological characteristics of a typical ice-cream mix

  2001cited by this paper
• Correlation of Drug Solubility with Trapping Efficiency and Release Characteristics of Alginate Beads

  1999cited by this paper
• Effect of aqueous polymer dispersions on properties of diclofenac/alginate beads and in vivo evaluation in rats

  1997cited by this paper
• Structure and behaviour in hydrophilic matrix sustained release dosage forms: 3. The influence of pH on the sustained-release performance and internal gel structure of sodium alginate matrices

  1995cited by this paper
• Rapid, sensitive, iron-based spectrophotometric methods for determination of peroxide values of food lipids.

  1994cited by this paper

• Valorization of hydroxycinnamic acids from corncob: synthesis of alkyl esters and encapsulation in alginate microparticles

  2026cites this paper
• Electrohydrodynamic encapsulation: A novel technique to enhance the stability of bioactive compounds in food

  2024cites this paper
• Insights from Syzygium aromaticum Essential Oil: Encapsulation, Characterization, and Antioxidant Activity

  2024cites this paper
• Development, characterization, and consumer acceptance evaluation of thermally stable capsule beads containing mixed extracts of green tea and turmeric

  2023cites this paper
• Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine: in-vitro optimization, skin histopathology and pharmacodynamic studies with in vitro/in vivo correlation

  2023cites this paper
• Development of an Encapsulation Method for Trapping the Active Materials from Sour Cherry Biowaste in Alginate Microcapsules

  2022cites this paper
• Encapsulated essential oils: a perspective in food preservation

  2022cites this paper
• Encapsulation of olive leaf antioxidants in microbeads: Application of alginate and chitosan as wall materials

  2022cites this paper
• Alginate-based hydrogels for trapping the polyphenols of Hibiscus sabdariffa: use of a statistical experimental design approach

  2022cites this paper
• Production of Freeze-Dried Flaxseed Oil Powders by Using Rocket Seed Gum as an Alternative Novel Encapsulation Agent to Improve Oxidative Stability

  2021cites this paper
• Lipases Immobilized onto Nanomaterials as Biocatalysts in Biodiesel Production: Scientific Context, Challenges, and Opportunities

  2021cites this paper
• Novel trends and opportunities for microencapsulation of flaxseed oil in foods: A review

  2021cites this paper
• Salep Glucomannan: Properties and Applications

  2021cites this paper
• Process optimization by response surface methodology for microencapsulation of pomegranate seed oil

  2021cites this paper