Vascular Microphysiological Systems to Model Diseases.

Human vascular microphysiological systems (MPS) represent promising three-dimensional in vitro models of normal and diseased vascular tissue. These systems build upon advances in tissue engineering, microfluidics, and stem cell differentiation and replicate key functional units of organs and tissues. Vascular models have been developed for the microvasculature as well as medium-size arterioles. Key functions of the vascular system have been reproduced and stem cells offer the potential to model genetic diseases and population variation in genes that may increase individual risk for cardiovascular disease. Such systems can be used to evaluate new therapeutics options.

• Publication year

  2020

• Venue

  Cell and Gene Therapy Insights

• Publication date

  2020-02-14

• Fields of study

  Biology, Medicine, Engineering

• Identifiers
  DOI 10.18609/cgti.2020.012PMID 32431950PMCID PMC7236815
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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