Anti‐hyperalgesic and anti‐allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Pain

• Publication date

  1998-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0304-3959(98)00071-2PMID 9718257
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Photochemically‐induced ischemia of the rat sciatic nerve produces a dose‐dependent and highly reproducible mechanical, heat and cold allodynia, and signs of spontaneous pain

  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1992cited by this paper
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• The threshold for the depressive effect of intrathecal morphine on the spinal nociceptive flexor reflex is increased during autotomy after sciatic nerve section in rats

  1991cited by this paper
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  1991cited by this paper
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• The Therapeutic Potential of Dual NMR (NOP/MOP) Agonism in Pain Management

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• Antinociceptive Effects of Sinomenine Combined With Ligustrazine or Paracetamol in Animal Models of Incisional and Inflammatory Pain

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• Single Cell Transcriptomic Analysis of Spinal Dmrt3 Neurons in Zebrafish and Mouse Identifies Distinct Subtypes and Reveal Novel Subpopulations Within the dI6 Domain

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• Nociceptin/orphanin FQ peptide receptor-related ligands as novel analgesics.

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• The nociceptin/orphanin FQ receptor system as a target to alleviate cancer‐induced bone pain in rats: Model validation and pharmacological evaluation

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• Evaluation of cebranopadol, a dually acting nociceptin/orphanin FQ and opioid receptor agonist in mouse models of acute, tonic, and chemotherapy-induced neuropathic pain

  2017cites this paper
• N/OFQ system in brain areas of nerve‐injured mice: its role in different aspects of neuropathic pain

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• Bifunctional opioid/nociceptin hybrid KGNOP1 effectively attenuates pain‐related behaviour in a rat model of neuropathy

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  2016cites this paper
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• A Review of the NOP (ORL-1)-Nociceptin/Orphanin FQ System Covering Receptor Structure, Distribution, Role in Analgesia and Reward and Interactions with Other Receptors

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• Nociceptin / orphanin FQ (NOP) receptors as novel potential target in the treatment of gastrointestinal diseases.

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• Comparison between Different Modulated Electrical Current on Painful Foot in Diabetic Polyneuropathic Patients

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• Role of spinal opioid receptor on the antiallodynic effect of intrathecal nociceptin in neuropathic rat.

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• Discovery of 1-(β-amino substituted-β-alanyl)-N,N-dimethylindoline-2-carboxamides as novel nonpeptide antagonists of nociceptin/orphanin FQ receptor: efficient design, synthesis, and structure-activity relationship studies.

  2012cites this paper
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  2011cites this paper
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• Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice

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• Antinociceptive effects of spinally administered nociceptin/orphanin FQ and its N-terminal fragments on capsaicin-induced nociception.

  2011cites this paper
• Minocycline reduces the injury-induced expression of prodynorphin and pronociceptin in the dorsal root ganglion in a rat model of neuropathic pain.

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• Nociceptin (1–13)NH2 Inhibits Stimulated Calcitonin-Gene-Related-Peptide Release From Primary Cultures of Rat Trigeminal Ganglia Neurones

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• The opioid peptide nociceptin/orphanin FQ mediates prostaglandin E2‐induced allodynia, tactile pain associated with nerve injury

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• Quantitative analysis of nociceptin in blood of patients with acute and chronic pain

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• Activation of spinal ORL‐1 receptors prevents acute cutaneous neurogenic inflammation: role of nociceptin‐induced suppression of primary afferent depolarization

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