Human Cdc14A Reverses CDK1 Phosphorylation of Cdc25A on Serines 115 and 320

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Cell Cycle

• Publication date

  2006-11-27

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.4161/cc.5.24.3566PMID 17172867
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers

  2006influential reference
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  2005cited by this paper
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  2004influential reference
• The CDC-14 phosphatase controls developmental cell-cycle arrest in C. elegans

  2004cited by this paper
• Fission yeast Clp1p phosphatase affects G2/M transition and mitotic exit through Cdc25p inactivation

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• Relocation of Aurora B from centromeres to the central spindle at the metaphase to anaphase transition requires MKlp2

  2004influential reference
• A role for the Cdc14-family phosphatase Flp1p at the end of the cell cycle in controlling the rapid degradation of the mitotic inducer Cdc25p in fission yeast

  2004cited by this paper
• Xenopus Cdc14α/β are localized to the nucleolus and centrosome and are required for embryonic cell division

  2004cited by this paper
• Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage.

  2003influential reference
• Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

  2003influential reference
• Chk1 Mediates S and G2 Arrests through Cdc25A Degradation in Response to DNA-damaging Agents*

  2003influential reference
• Dual mode of degradation of Cdc25 A phosphatase

  2002influential reference
• Regulation of G2/M events by Cdc25A through phosphorylation‐dependent modulation of its stability

  2002influential reference
• The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo

  2002influential reference
• Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation

  2002influential reference
• Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

  2002influential reference
• Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase.

  2002influential reference
• Flp1, a fission yeast orthologue of the s. cerevisiae CDC14 gene, is not required for cyclin degradation or rum1p stabilisation at the end of mitosis.

  2001cited by this paper
• The ATM–Chk2–Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

  2001influential reference
• Regulation of the Anaphase-promoting Complex by the Dual Specificity Phosphatase Human Cdc14a*

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• Fission yeast Clp1p phosphatase regulates G2/M transition and coordination of cytokinesis with cell cycle progression.

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• The Human Cdc14 Phosphatases Interact with and Dephosphorylate the Tumor Suppressor Protein p53*

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• Cfi1 prevents premature exit from mitosis by anchoring Cdc14 phosphatase in the nucleolus

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• Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.

  1999influential reference
• CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase

  1999influential reference
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  1999influential reference
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  1998influential reference
• A Family of Putative Tumor Suppressors Is Structurally and Functionally Conserved in Humans and Yeast*

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  1991influential reference
• The cdc25 protein contains an intrinsic phosphatase activity.

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• Targeting CDK1 in cancer: mechanisms and implications

  2023cites this paper
• A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

  2021cites this paper
• A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

  2021cites this paper
• Cdc14a has a role in spermatogenesis, sperm maturation and male fertility.

  2020cites this paper
• Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine-induced liver cancer via inhibition of cell division cycle 25A

  2020cites this paper
• Phosphorylation of CDC25A on SER283 in late S/G2 by CDK/cyclin complexes accelerates mitotic entry

  2016cites this paper
• Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategies

  2016cites this paper
• Oncoprotein YAP Regulates the Spindle Checkpoint Activation in a Mitotic Phosphorylation-dependent Manner through Up-regulation of BubR1*

  2015cites this paper
• Elucidating Human Phosphatase-Substrate Networks

  2013cites this paper
• Phosphorylation Mediated Regulation of Cdc25 Activity, Localization and Stability

  2012influential citation
• Phospho-regulation of KIBRA by CDK1 and CDC14 phosphatase controls cell-cycle progression.

  2012cites this paper
• Human Cdc14A becomes a cell cycle gene in controlling Cdk1 activity at the G2/M transition

  2011cites this paper
• Human Cdc14B Promotes Progression through Mitosis by Dephosphorylating Cdc25 and Regulating Cdk1/Cyclin B Activity

  2011influential citation
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  2010cites this paper
• Human Cdc14A Phosphatase Modulates the G2/M Transition through Cdc25A and Cdc25B

  2010cites this paper
• Cdc14: a highly conserved family of phosphatases with non-conserved functions?

  2010cites this paper
• C-terminal domain phosphorylation of ERK3 controlled by Cdk1 and Cdc14 regulates its stability in mitosis.

  2010cites this paper
• Human Cdc25A phosphatase has a non‐redundant function in G2 phase by activating Cyclin A‐dependent kinases

  2009cites this paper
• Characterization of Human Cdc14B's function in centrosome cycle control

  2008cites this paper
• Cds1 controls the release of Cdc14-like phosphatase Flp1 from the nucleolus to drive full activation of the checkpoint response to replication stress in fission yeast.

  2008cites this paper
• The Flp1/Clp1 phosphatase cooperates with HECT-type Pub1/2 protein-ubiquitin ligases in Schizosaccharomyces pombe

  2008cites this paper
• Cellular and Biochemical Regulation of Cdc25A Phosphatase by Nitrosative Stress

  2008cites this paper
• Systems Biology of Mitosis

  2008cites this paper
• CDC25A: a rebel within the CDC25 phosphatases family?

  2008cites this paper
• Regulation of the Rab5 GTPase-activating Protein RN-tre by the Dual Specificity Phosphatase Cdc14A in Human Cells*

  2007cites this paper