Medial temporal lobe connectivity and its associations with cognition in early Alzheimer’s disease

D. Berron,D. van Westen,R. Ossenkoppele,O. Strandberg,O. Hansson

Published 2020 in Brain : a journal of neurology

ABSTRACT

Berron et al. show that functional connectivity between the medial temporal lobe and the anterior-temporal system is reduced in the earliest stages of Alzheimer’s disease, before connectivity with the posterior-medial system is affected. The reduced functional connectivity is associated with impaired memory performance.

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