Contemporary Reviews in Cardiovascular Medicine Cardioprotective Effects of Insulin How Intensive Insulin Therapy May Benefit Cardiac Surgery Patients

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Comparison of insulin action on glucose versus potassium uptake in humans.

  2011cited by this paper
• The effect of tight glycaemic control, during and after cardiac surgery, on patient mortality and morbidity: A systematic review and meta-analysis

  2011cited by this paper
• High-dose insulin in experimental myocardial infarction in rabbits: protection against effects of hyperglycaemia.

  2011cited by this paper
• Endothelial-cardiomyocyte crosstalk enhances pharmacological cardioprotection.

  2011cited by this paper
• Glucose-insulin-potassium therapy in adult patients undergoing cardiac surgery: a meta-analysis.

  2011cited by this paper
• Meta-analysis of cohort and case-control studies of type 2 diabetes mellitus and risk of atrial fibrillation.

  2011cited by this paper
• Comparison of glucose-insulin-potassium and insulin-glucose as adjunctive therapy in acute myocardial infarction: a contemporary meta-analysis of randomised controlled trials

  2010cited by this paper
• Effect of perioperative glucose-insulin-potassium infusions on mortality and atrial fibrillation after coronary artery bypass grafting: a systematic review and meta-analysis.

  2010cited by this paper
• Oxidative stress and diabetic cardiovascular disorders: roles of mitochondria and NADPH oxidase.

  2010cited by this paper
• DNA Damage Links Mitochondrial Dysfunction to Atherosclerosis and the Metabolic Syndrome

  2010cited by this paper
• Effects of GIK (glucose-insulin-potassium) on stress-induced myocardial ischaemia.

  2010cited by this paper
• Endothelial Dysfunction, Inflammation, and Apoptosis in Diabetes Mellitus

  2010cited by this paper
• Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis.

  2010cited by this paper
• Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

  2010cited by this paper
• The link between diabetes and atrial fibrillation: cause or correlation?

  2010cited by this paper
• Hyperglycemia: a prothrombotic factor?

  2010cited by this paper
• Insulin attenuates myocardial ischemia/reperfusion injury via reducing oxidative/nitrative stress.

  2010cited by this paper
• Anti-inflammatory action of insulin via induction of Gadd45-β transcription by the mTOR signaling pathway

  2010cited by this paper
• High levels of glucose induce apoptosis in cardiomyocyte via epigenetic regulation of the insulin-like growth factor receptor.

  2010cited by this paper
• A meta-analysis of glucose-insulin-potassium therapy for treatment of acute myocardial infarction.

  2010cited by this paper
• High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c‐Jun N‐terminal kinase

  2010cited by this paper
• Insulin inhibits leukocyte-endothelium adherence via an Akt-NO-dependent mechanism in myocardial ischemia/reperfusion.

  2009cited by this paper
• Intensive versus Conventional Glucose Control in Critically Ill Patients

  2009cited by this paper
• Hyperglycaemia as part of the stress response: the underlying mechanisms.

  2009cited by this paper
• Hyperglycaemia as part of the stress response: the underlying mechanisms.

  2009cited by this paper
• Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data

  2009cited by this paper
• Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation.

  2009cited by this paper
• Insulin as an anti-inflammatory and antiatherogenic modulator.

  2009cited by this paper
• Mitochondrial hexokinase and cardioprotection of the intact heart

  2009cited by this paper
• Insulin inhibits myocardial ischemia-induced apoptosis and alleviates chronic adverse changes in post-ischemic cardiac structure and function

  2009cited by this paper
• High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation.

  2009cited by this paper
• Long-term outcomes in individuals with prolonged PR interval or first-degree atrioventricular block.

  2009cited by this paper
• Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study.

  2009cited by this paper
• Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

  2009cited by this paper
• The effect of glucose–insulin–potassium treatment on myocardial oxidative stress in patients with acute coronary syndromes undergoing percutaneous coronary intervention

  2008cited by this paper
• Insulin inhibits tumor necrosis factor-α induction in myocardial ischemia/reperfusion: Role of Akt and endothelial nitric oxide synthase phosphorylation*

  2008cited by this paper
• Insulin-induced myocardial protection in isolated ischemic rat hearts requires p38 MAPK phosphorylation of Hsp27.

  2008cited by this paper
• Glucose induces apoptosis of cardiomyocytes via microRNA-1 and IGF-1.

  2008cited by this paper
• Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels

  2008cited by this paper
• Hyperglycaemia blocks sevoflurane-induced postconditioning in the rat heart in vivo: cardioprotection can be restored by blocking the mitochondrial permeability transition pore.

  2008cited by this paper
• Atrial fibrosis and the mechanisms of atrial fibrillation.

  2007cited by this paper
• Insulin Antagonizes Interleukin-6 Signaling and Is Anti-inflammatory in 3T3-L1 Adipocytes*

  2007cited by this paper
• Cardiovascular actions of insulin.

  2007cited by this paper
• Survival benefits of intensive insulin therapy in critical illness: impact of maintaining normoglycemia versus glycemia-independent actions of insulin.

  2006cited by this paper
• The mTOR pathway in the control of protein synthesis.

  2006cited by this paper
• High glucose alters cardiomyocyte contacts and inhibits myofibrillar formation.

  2006cited by this paper
• Hyperglycemia is a marker for poor outcome in the postoperative pediatric cardiac patient*

  2006cited by this paper
• Signalling via the reperfusion injury signalling kinase (RISK) pathway links closure of the mitochondrial permeability transition pore to cardioprotection.

  2006cited by this paper
• Intensive insulin therapy in the medical ICU.

  2006cited by this paper
• Intensive insulin therapy in high-risk cardiac surgery patients: evidence from the Leuven randomized study.

  2006cited by this paper
• Cellular mechanisms responsible for the inotropic action of insulin on failing human myocardium.

  2006cited by this paper
• Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes.

  2006cited by this paper
• Reactive oxygen species have a causal role in multiple forms of insulin resistance

  2006cited by this paper
• Insulin Causes [Ca ]i-Dependent and [Ca ]i-Independent Positive Inotropic Effects in Failing Human Myocardium

  2005cited by this paper
• Insulin Causes [Ca2+]i-Dependent and [Ca2+]i-Independent Positive Inotropic Effects in Failing Human Myocardium

  2005cited by this paper
• Intensive insulin therapy protects the endothelium of critically ill patients.

  2005cited by this paper
• Impact of admission hyperglycemia on hospital mortality in various intensive care unit populations*

  2005cited by this paper
• Hyperglycemia is associated with adverse outcomes in patients receiving total parenteral nutrition.

  2005cited by this paper
• Insulin improves myocardial blood flow in patients with type 2 diabetes and coronary artery disease.

  2005cited by this paper
• Persistent hyperglycemia is predictive of outcome in critically ill trauma patients.

  2005cited by this paper
• Admission hyperglycemia is predictive of outcome in critically ill trauma patients.

  2005cited by this paper
• Glycemic and nonglycemic effects of insulin: how do they contribute to a better outcome of critical illness?

  2005cited by this paper
• Blockade of NF-κB improves cardiac function and survival without affecting inflammation in TNF-α-induced cardiomyopathy

  2005cited by this paper
• Effect of hyperglycemia and continuous intravenous insulin infusions on outcomes of cardiac surgical procedures: the Portland Diabetic Project.

  2004cited by this paper
• New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway.

  2004cited by this paper
• Effect of an intensive glucose management protocol on the mortality of critically ill adult patients.

  2004cited by this paper
• Impaired fasting glucose and cardiogenic shock in patients with acute myocardial infarction.

  2004cited by this paper
• Insulin resistance in adult cardiomyocytes undergoing dedifferentiation: role of GLUT4 expression and translocation

  2004cited by this paper
• Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense

  2004cited by this paper
• Effect of acute hyperglycaemia and diabetes mellitus with and without short-term insulin treatment on myocardial ischaemic late preconditioning in the rabbit heart in vivo

  2003cited by this paper
• Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients.

  2003cited by this paper
• Diabetes, oxidative stress, and antioxidants: A review

  2003cited by this paper
• Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species.

  2003cited by this paper
• Increased myocardial NADPH oxidase activity in human heart failure.

  2003cited by this paper
• Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts

  2003cited by this paper
• Intensive insulin therapy in critically ill patients.

  2002cited by this paper
• Effects of Insulin on Coronary Blood Flow in Anesthetized Pigs

  2002cited by this paper
• Regional myocardial blood flow and glucose utilization during fasting and physiological hyperinsulinemia in humans.

  2002cited by this paper
• Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

  2002cited by this paper
• Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans: Role of Oxidative Stress

  2002cited by this paper
• Ischemia-Reperfusion : The Roles of PI 3-Kinase , Akt , and Endothelial Nitric Oxide Nitric Oxide Mediates the Antiapoptotic Effect of Insulin in Myocardial

  2002cited by this paper
• Hyperglycemia Prevents Isoflurane-induced Preconditioning against Myocardial Infarction

  2002cited by this paper
• Effects of vitamin A and insulin on the antioxidative state of diabetic rat heart: a comparison study with combination treatment

  2002cited by this paper
• Mitochondrial Binding of Hexokinase II Inhibits Bax-induced Cytochrome c Release and Apoptosis*

  2002cited by this paper
• Hyperglycemia exaggerates ischemia-reperfusion-induced cardiomyocyte injury: reversal with endothelin antagonism.

  2002cited by this paper
• Insulin Inhibits NFκB and MCP-1 Expression in Human Aortic Endothelial Cells

  2001cited by this paper
• The Effect of Insulin Cardioplegia on Atrial Fibrillation After High-Risk Coronary Bypass Surgery: A Double-Blinded, Randomized, Controlled Trial

  2001cited by this paper
• Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site.

  2001cited by this paper
• Akt Activation Preserves Cardiac Function and Prevents Injury After Transient Cardiac Ischemia In Vivo

  2001cited by this paper
• Insulin inhibits NFkappaB and MCP-1 expression in human aortic endothelial cells.

  2001cited by this paper
• Insulin-stimulated Activation of eNOS Is Independent of Ca2+ but Requires Phosphorylation by Akt at Ser1179 *

  2001cited by this paper
• , Weidong Akt Activation of PI 3 Kinase / Induced Apoptosis Through − Insulin Prevents Cardiomyocytes From Oxidative Stress

  2000cited by this paper
• Effect of insulin on human aortic endothelial nitric oxide synthase.

  2000cited by this paper
• Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells.

  2000cited by this paper
• The mitochondrial permeability transition pore and its role in cell death.

  1999cited by this paper
• Nitric Oxide Inhibits Caspase-3 by S-Nitrosationin Vivo *

  1999cited by this paper
• ERK activation protects against DNA damage and apoptosis in hyperoxic rat AEC2.

  1999cited by this paper
• Influence of Age on Inotropic Response to Insulin and Insulin-Like Growth Factor I in Spontaneously Hypertensive Rats: Role of Nitric Oxide

  1999cited by this paper
• Acute hyperglycemia abolishes ischemic preconditioning in vivo.

  1998cited by this paper
• Role of binding proteins to IRS-1 in insulin signalling

  1998cited by this paper

• Carotid intima-media thickness measurement as a risk predictor of transient ischemic attack

  2011cites this paper
• Medición del espesor miointimal carotídeo como predictor de riesgo de accidente isquémico transitorio

  2011cites this paper