Cnidarian-microbe interactions and the origin of innate immunity in metazoans.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Annual Review of Microbiology

• Publication date

  2013-09-11

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1146/annurev-micro-092412-155626PMID 23808329
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• A pathway that links reproductive status to lifespan in Caenorhabditis elegans

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• Inter-kingdom signalling: communication between bacteria and their hosts

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• Cryptic complexity captured: the Nematostella genome reveals its secrets.

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• Horizontal gene transfer in eukaryotic evolution

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• FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system.

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• Long-term maintenance of species-specific bacterial microbiota in the basal metazoan Hydra

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• Reduced Paneth cell alpha-defensins in ileal Crohn's disease.

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• Antimicrobial peptides in Drosophila: structures, activities and gene regulation.

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• Embryogenesis in hydra.

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