Bone regeneration by implantation of purified, culture‐expanded human mesenchymal stem cells

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Journal of Orthopaedic Research

• Publication date

  1998-03-01

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1002/JOR.1100160202PMID 9621889
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phenotypic and functional comparison of cultures of marrow‐derived mesenchymal stem cells (MSCs) and stromal cells

  1998cited by this paper
• Growth kinetics, self‐renewal, and the osteogenic potential of purified human mesenchymal stem cells during extensive subcultivation and following cryopreservation

  1997cited by this paper
• Culture-Expanded, Bone Marrow-Derived Mesenchymal Stem Cells Can Regenerate a Critical-Sized Segmental Bone Defect

  1997cited by this paper
• The Effect of Aging on Bone Formation in Porous Hydroxyapatite: Biochemical and Histological Analysis

  1997cited by this paper
• Single‐Colony Derived Strains of Human Marrow Stromal Fibroblasts Form Bone After Transplantation In Vivo

  1997cited by this paper
• Monoclonal antibodies reactive with human osteogenic cell surface antigens.

  1997cited by this paper
• Culture expanded canine mesenchymal stem cells possess osteochondrogenic potential in vivo and in vitro.

  1997cited by this paper
• Osteogenic differentiation of purified, culture‐expanded human mesenchymal stem cells in vitro

  1997cited by this paper
• Cytokine expression by human marrow‐derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL‐1α

  1996cited by this paper
• Stimulation of new bone formation by direct transfer of osteogenic plasmid genes.

  1996cited by this paper
• Qualitative and quantitative analysis of orthotopic bone regeneration by marrow

  1996cited by this paper
• Effect of recombinant human osteogenic protein-1 on healing of segmental defects in non-human primates.

  1995cited by this paper
• Age-related bone loss. A hypothesis and initial assessment in mice.

  1995cited by this paper
• Myogenic Expression of Mesenchymal Stem Cells within Myotubes of mdx Mice in Vitro and in Vivo

  1995cited by this paper
• Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice.

  1995cited by this paper
• Bone progenitor cell deficits and the age-associated decline in bone repair capacity

  1995cited by this paper
• Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5‐azacytidine

  1995cited by this paper
• Repair of Articular Cartilage Defects Using Mesenchymal Stem Cells

  1995cited by this paper
• Induction of bone by a demineralized bone matrix gel: A study in a rat femoral defect model

  1995cited by this paper
• Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage.

  1994cited by this paper
• Mesenchymal stem cells in bone development, bone repair, and skeletal regenaration therapy

  1994cited by this paper
• The effect of osteogenin (a bone morphogenetic protein) on the formation of bone in orthotopic segmental defects in rats.

  1994cited by this paper
• Healing of large segmental defects in rat femurs is aided by RhBMP-2 in PLGA matrix.

  1994cited by this paper
• Lymphocyte activation

  1994cited by this paper
• Histomorphometric analysis of the repair of a segmental diaphyseal defect with ceramic and titanium fibermetal implants: Effects of bone marrow

  1994cited by this paper
• Osteogenesis in Marrow-Derived Mesenchymal Cell Porous Ceramic Composites Transplanted Subcutaneously: Effect of Fibronectin and Laminin on Cell Retention and Rate of Osteogenic Expression

  1992cited by this paper
• Characterization of cells with osteogenic potential from human marrow.

  1992cited by this paper
• The rnu (Rowett Nude) and rnuN ( nznu, New Zealand Nude) Rat: An Update

  1992cited by this paper
• The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats.

  1992cited by this paper
• Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies.

  1992cited by this paper
• Culture‐expanded human periosteal‐derived cells exhibit osteochondral potential in vivo

  1991cited by this paper
• Mesenchymal Stem Cells

  1991cited by this paper
• The origin of bone formed in composite grafts of porous calcium phosphate ceramic loaded with marrow cells.

  1991cited by this paper
• The osteogenic potential of culture-expanded rat marrow mesenchymal cells assayed in vivo in calcium phosphate ceramic blocks.

  1991cited by this paper
• Effects of donor age on osteogenic cells of rat bone marrow in vitro.

  1990cited by this paper
• A monoclonal antibody against the surface of osteoblasts recognizes alkaline phosphatase isoenzymes in bone, liver, kidney, and intestine.

  1990cited by this paper
• Repair of bone defects with marrow cells and porous ceramic. Experiments in rats.

  1989cited by this paper
• Novel regulators of bone formation: molecular clones and activities.

  1988cited by this paper
• Hydroxyapatite and tricalcium phosphate bone graft substitutes.

  1987cited by this paper
• Porous hydroxyapatite as a bone graft substitute in diaphyseal defects: A histometric study

  1987cited by this paper
• Bone deficit in ovariectomized rats. Functional contribution of the marrow stromal cell population and the effect of oral dihydrotachysterol treatment.

  1986cited by this paper
• The healing of segmental bone defects induced by demineralized bone matrix. A radiographic and biomechanical study.

  1984cited by this paper
• The role of bone marrow in bone morphogenetic protein-induced repair of femoral massive diaphyseal defects.

  1982cited by this paper

• Revolutionizing Nonunion Treatment: The Expanding Role of Local Biological Therapies.

  2025cites this paper
• The Evolving Role of Stem Cells in Oral Health and Regeneration: A Systematic Review

  2025cites this paper
• Revolutionizing bone regeneration and wound healing: Mechanical stromal vascular fraction and hyaluronic acid in a mouse calvarial defect model

  2025cites this paper
• Mesenchymal Stem Cells-Derived Exosomes Combined With Bone Grafts Ameliorate Bone Regeneration in Mandibular Defects

  2025cites this paper
• Histological changes in the experimentally damaged bone tissue of rabbits following injection of stem cells

  2025cites this paper
• Designer micro/nano-crumpled MXene multilayer coatings accelerate osteogenesis and regulate macrophage polarization

  2024cites this paper
• Advances in self-powered biomaterials for bone defect repair

  2024cites this paper
• KDELR2 promotes bone marrow mesenchymal stem cell osteogenic differentiation via GSK3β/β-catenin signaling pathway

  2024cites this paper
• Scalable manufacture of therapeutic mesenchymal stromal cell products on customizable microcarriers in vertical wheel bioreactors that improve direct visualization, product harvest, and cost

  2024cites this paper
• Graphene and its hybrid nanocomposite: A Metamorphoses elevation in the field of tissue engineering

  2024cites this paper
• Cell membrane vesicles derived from hBMSCs and hUVECs enhance bone regeneration

  2024cites this paper
• Current application of dexamethasone-incorporated drug delivery systems for enhancing bone formation

  2023cites this paper
• Exogenously delivered iPSCs disrupt the natural repair response of endogenous MPCs after bone injury

  2023cites this paper
• Adherence and activation of human mesenchymal stromal cells on brushite coated porous titanium

  2023cites this paper
• TMT-Based Quantitative Proteomics Analysis Reveals Differentially Expressed Proteins between Different Sources of hMSCs

  2023cites this paper
• The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

  2022cites this paper
• A Systematic Review of Bone Marrow Stromal Cells and Periosteum-Derived Cells for Bone Regeneration

  2022cites this paper
• Mesenchymal Stem Cell Therapeutic Potential in Regenerative Medicine and Its Future Direction

  2022cites this paper
• Impact of Fluid Dynamics on the Viability and Differentiation Capacity of 3D-Cultured Jaw Periosteal Cells

  2022cites this paper
• Novel Techniques and Future Perspective for Investigating Critical-Size Bone Defects

  2022cites this paper
• Intravenous Transplantation of Human Hair Follicle-Derived Mesenchymal Stem Cells Ameliorates Trabecular Bone Loss in Osteoporotic Mice

  2022cites this paper
• Regulatory Mechanisms in Biosystems

  2022cites this paper
• Partial load-bearing rabbit ulnar segmental defects are regenerated with biocompatible grafts with or without bone marrow-derived mesenchymal stem cells

  2022influential citation
• Effects of transplanted mesenchymal stem cells on repair of the lung tissue of rats with experimental pulmonary fibrosis

  2022cites this paper
• Adipose-derived stromal/stem cells for bone tissue engineering applications

  2022cites this paper
• Comparative characteristic study from bone marrow-derived mesenchymal stem cells

  2021cites this paper
• Effect of mesenchymal stem cells on cytochrome-c release and inflammation in colon 1 cancer induced by 1,2-dimethylhydrazine in Wistar albino rats

  2021cites this paper
• Extracellular Vesicles as Intercellular Communication Vehicles in Regenerative Medicine

  2021cites this paper
• Potency analysis of cellular therapies: the role of molecular assays

  2021cites this paper
• Effect of mesenchymal stem cells on cytochrome-c release and inflammation in colon cancer induced by 1,2-dimethylhydrazine in Wistar albino rats

  2021cites this paper
• Sternal Bone Marrow Harvesting and Culturing Techniques from Patients Undergoing Cardiac Surgery

  2021cites this paper
• Adipose-derived mesenchymal stem cells combined with platinum nanoparticles accelerate fracture healing in a rat tibial fracture model

  2021cites this paper
• Biomaterial-based strategies for maxillofacial tumour therapy and bone defect regeneration

  2021cites this paper
• Comparative analysis of plasma-derived albumin scaffold, alveolar osteoblasts and synthetic membrane in critical mandibular bone defects: An experimental study on rats

  2021cites this paper
• A Cell-Based Approach to Dental Pulp Regeneration Using Mesenchymal Stem Cells: A Scoping Review

  2021cites this paper
• Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard

  2021cites this paper
• Controlled Osteogenic Differentiation of Human Mesenchymal Stem Cells Using Dexamethasone-Loaded Light-Responsive Microgels.

  2021cites this paper
• A Comparative In Vitro and In Vivo Study of Osteogenicity by Using Two Biomaterials and Two Human Mesenchymal Stem Cell Subtypes

  2021cites this paper
• Novel chitosan-based bone substitute. A summary of in vitro and in vivo evaluation

  2021cites this paper
• Coculture of Endothelial and Stromal Cells to Promote Concurrent Osteogenesis and Vasculogenesis

  2021cites this paper
• Coupling Osteogenesis and Vasculogenesis in Engineered Orthopedic Tissues

  2020cites this paper
• Mesenchymal stem cells could be considered as a candidate for further studies in cell-based therapy of Alzheimer's disease via targeting the signaling pathways.

  2020cites this paper
• Mesenchymal stem cell/multipotent stromal cell augmentation of wound healing: lessons from the physiology of matrix and hypoxia support.

  2020cites this paper
• Longtime Outcome After Intraosseous Application of Autologous Mesenchymal Stromal Cells in Pediatric Patients and Young Adults with Avascular Necrosis After Steroid or Chemotherapy

  2020cites this paper
• Role of mesenchymal stem cells in bone fracture repair and regeneration

  2020cites this paper
• Development of a Cost-effective Xeno-free Conditioned Medium Containing Human Basic Fibroblast Growth Factor for the Expansion of Human Mesenchymal Stem Cell

  2020cites this paper
• Mesenchymal stromal cells; a new horizon in regenerative medicine

  2020cites this paper
• The Habitat Assay, a Platform to Study In Vivo Properties of Human Mesenchymal Stem Cells

  2020cites this paper
• Skeletal tissue engineering

  2020cites this paper
• Tissue Engineering Strategies for Tooth and Dento-alveolar Region with Engineered Biomaterial and Stem Cells

  2020cites this paper
• Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells

  2020cites this paper
• Peripheral Blood Stem Cells

  2019cites this paper
• Sulfonated Polyrotaxane Surfaces with Basic Fibroblast Growth Factor Alter the Osteogenic Potential of Human Mesenchymal Stem Cells in Short-Term Culture.

  2019cites this paper
• Mesenchymal stem cell seeded, biomimetic 3D printed scaffolds induce complete bridging of femoral critical sized defects.

  2019cites this paper
• Bibliometric Analysis of the Journal of Orthopaedic Research from 1991 To 2018

  2019cites this paper
• Regenerative Medicine

  2019cites this paper
• In situ miRNA delivery from a hydrogel promotes osteogenesis of encapsulated mesenchymal stromal cells

  2019cites this paper
• Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles

  2019cites this paper
• Advanced Functional Biomaterials for Stem Cell Delivery in Regenerative Engineering and Medicine

  2019cites this paper
• Calcified Algae for Tissue Engineering

  2019cites this paper
• a novel hybrid compound llP2a-alendronate accelerates open fracture healing in a rabbit model

  2019cites this paper
• Effect of SDF-1 with biphasic ceramic-like bone graft on the repair of rabbit radial defect

  2019cites this paper
• Exosomes in the Repair of Bone Defects: Next-Generation Therapeutic Tools for the Treatment of Nonunion

  2019cites this paper
• Engineered Mesenchymal Stem Cells for Targeting Solid Tumors: Therapeutic Potential beyond Regenerative Therapy

  2019cites this paper
• Strategy for the Generation of Engineered Bone Constructs Based on Umbilical Cord Mesenchymal Stromal Cells Expanded with Human Platelet Lysate

  2019cites this paper
• Macrophage Transplantation Fails to Improve Repair of Critical-Sized Calvarial Defects.

  2019cites this paper
• Perfusion Bioreactor Culture of Bone Marrow Stromal Cells Enhances Cranial Defect Regeneration

  2019cites this paper
• Predictive Factors and Rates of Fusion in Minimally Invasive Transforaminal Lumbar Interbody Fusion Utilizing rhBMP-2 or Mesenchymal Stem Cells

  2019cites this paper
• Polymer-based calcium phosphate scaffolds for tissue engineering applications

  2019cites this paper
• A novel hybrid compound LLP2A-alendronate accelerates open fracture healing in a rabbit model

  2019cites this paper
• Platelet lysate outperforms FCS and human serum for co-culture of primary human macrophages and hMSCs

  2019cites this paper
• LOC103691336/miR‐138‐5p/BMPR2 axis modulates Mg‐mediated osteogenic differentiation in rat femoral fracture model and rat primary bone marrow stromal cells

  2019cites this paper
• Biocompatibility of the human mesenchymal stem cells with bovine bone tissue at the cellular level in vitro

  2018cites this paper
• Development of an innovative bioreactor system for human bone tissue engineering

  2018cites this paper
• Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas

  2018cites this paper
• Engineering the Surface of Therapeutic "Living" Cells.

  2018cites this paper
• Bone Marrow Cell Therapy on 1,2-Dimethylhydrazine (DMH)-Induced Colon Cancer in Rats

  2018cites this paper
• The Effects of Platelet-Derived Growth Factor-BB on Bone Marrow Stromal Cell-Mediated Vascularized Bone Regeneration

  2018cites this paper
• Human Bone Marrow Mesenchymal Stromal Cells Promote Bone Regeneration in a Xenogeneic Rabbit Model: A Preclinical Study

  2018cites this paper
• Caveolae-mediated mesenchymal stem cell labelling by PSS-coated PLGA PFOB nano-contrast agent for MRI

  2018cites this paper
• Cytotherapy using stromal cells: Current and advance multi-treatment approaches.

  2018cites this paper
• Growth Factors for Site Preparation: Current Science, Indications, and Practice

  2018cites this paper
• Interacción entre las vías hif, notch y sumo y su implicación en la biología de las hmscs

  2018cites this paper
• Imaging in Clinical and Preclinical Practice

  2018cites this paper
• Effect of Poly(sophorolipid) Functionalization on Human Mesenchymal Stem Cell Osteogenesis and Immunomodulation.

  2018cites this paper
• Diaphyseal long bone nonunions — types, aetiology, economics, and treatment recommendations

  2018cites this paper
• Maxillary Sinus Augmentation Procedures

  2018cites this paper
• Isolation, cultivation, and characterization of human mesenchymal stem cells

  2018cites this paper
• STAT-3 regulation of CXCR4 is necessary for the prenylflavonoid Icaritin to enhance mesenchymal stem cell proliferation, migration and osteogenic differentiation.

  2018cites this paper
• Cell aggregation enhances bone formation by human mesenchymal stromal cells.

  2017cites this paper
• In vitro Generated Mesenchymal Stem Cells: Suitable Tools to Target Insulin Dependent Diabetes Mellitus?

  2017cites this paper
• Evaluation of the effects of the combination of autologous mesenchymal stem cells and platelet-rich plasma on structural bone allograft healing

  2017cites this paper
• Interleukin-25 primed mesenchymal stem cells achieve better therapeutic effects on dextran sulfate sodium-induced colitis via inhibiting Th17 immune response and inducing T regulatory cell phenotype.

  2017cites this paper
• Preliminary studies on the use of exosomes as dendrimer carriers

  2017cites this paper
• Angiogenic conditioning of peripheral blood mononuclear cells promotes fracture healing

  2017cites this paper
• Cytocompatibility testing of hydrogels toward bioprinting of mesenchymal stem cells.

  2017cites this paper
• Histopathological evaluation of the effect of systemic thymoquinone administration on healing of bone defects in rat tibia

  2017cites this paper
• Bone Regeneration Using Adipose-Derived Stem Cells with Fibronectin in Dehiscence-Type Defects Associated with Dental Implants: An Experimental Study in a Dog Model.

  2017cites this paper
• The Top 50 Most Cited Articles in Cartilage Regeneration

  2017cites this paper
• Bone regeneration in mandibular fractures after the application of autologous mesenchymal stem cells, a randomized clinical trial

  2017cites this paper