Continuous intravenous administration of live genetically modified salmonella typhimurium in patients with metastatic melanoma.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of immunotherapy

• Publication date

  2003-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/00002371-200303000-00011PMID 12616110PMCID PMC2656370
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma.

  2002cited by this paper

• Flagella-overexpressing bacteria with inducible lysis capability delivering cGAMP intratracheally for enhanced anticancer immunotherapy.

  2026cites this paper
• Current status and future perspectives of multi‐modal bacteria‐based cancer therapies

  2025cites this paper
• Engineered Bacteria-Nano Hybrid System: The Intelligent Drug Factory for Next-Generation Cancer Immunotherapy

  2025cites this paper
• Attenuated Salmonella secreting interleukin-21 activates T-cells and induces anti-tumor effects

  2025cites this paper
• Targeting Cancers with Microrobots and Bacteriobots.

  2025cites this paper
• Stroma content in triple-negative breast cancer spheroid models regulates penetration and efficacy of tumor-targeting Salmonella typhimurium

  2025cites this paper
• Allosteric deimmunisation of a Salmonella phosphatase enhances catalytic function

  2025cites this paper
• Engineered bacteria and bacteria-derived nanomaterials for cancer therapy: Mechanisms, designs and advances

  2025cites this paper
• Harnessing live vectors for cancer vaccines: Advancing therapeutic immunotherapy

  2025cites this paper
• Tumor-stromal opening via S. typhimurium VNP20009 administration for complete inhibition of refractory tumor growth with liposomal anticancer drugs.

  2025cites this paper
• A scalable architecture for tuning multistate differentiation ratios in synthetic microbial consortia

  2025cites this paper
• Salmonella-Induced Cell Death in Cancer Immunotherapy: What Lies Beneath?

  2025cites this paper
• Engineered bacteria for cancer therapy: Advancements, challenges, and future directions

  2025cites this paper
• Innovative Applications of Bacteria and Their Derivatives in Targeted Tumor Therapy.

  2025cites this paper
• A Review of Engineered Bacterial Nanobots for Targeted Cancer Therapy

  2025cites this paper
• VNP20009-Abvec-Igκ-MIIP suppresses ovarian cancer progression by modulating Ras/MEK/ERK signaling pathway

  2024cites this paper
• Targeting clonal mutations with synthetic microbes.

  2024cites this paper
• Harnessing Bacterial Agents to Modulate the Tumor Microenvironment and Enhance Cancer Immunotherapy

  2024cites this paper
• Engineered VNP20009 expressing IL-15&15Rα augments anti-tumor immunity for bladder cancer treatment.

  2024cites this paper
• Flagellate bacteria‐mediated tumour antigen delivery: A novel approach to enhance dendritic cell activation for in situ cancer vaccination

  2024cites this paper
• Enhanced anti-cancer efficacy of arginine deaminase expressed by tumor-seeking Salmonella Gallinarum

  2024cites this paper
• Bacterial derivatives mediated drug delivery in cancer therapy: a new generation strategy

  2024cites this paper
• Genetic engineering of Salmonella spp. for novel vaccine strategies and therapeutics

  2024cites this paper
• Attenuated mutants of Salmonella enterica Typhimurium mediate melanoma regression via an immune response

  2024cites this paper
• Unveiling the intratumoral microbiota within cancer landscapes

  2024cites this paper
• Tumor Stroma Content Regulates Penetration and Efficacy of Tumor-targeting Bacteria

  2024cites this paper
• Hypoxia-Targeting Bacteria in Cancer Therapy.

  2024cites this paper
• Oncolytic mineralized bacteria as potent locally administered immunotherapeutics

  2024cites this paper
• Salmonella-mediated methionine deprivation drives immune activation and enhances immune checkpoint blockade therapy in melanoma

  2024cites this paper
• Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy

  2023cites this paper
• A Systemic Review on Fitness and Survival of Salmonella in Dynamic Environment and Conceivable Ways of Its Mitigation

  2023cites this paper
• Salmonella enterica and outer membrane vesicles are current and future options for cancer treatment

  2023cites this paper
• Bacterial immunotherapy: is it a weapon in our arsenal in the fight against cancer?

  2023cites this paper
• Clostridium Bacteria: The Team of Microscopic Oncologists

  2023cites this paper
• Engineered oncolytic bacteria HCS1 exerts high immune stimulation and safety profiles for cancer therapy

  2023cites this paper
• Designer probiotics: Opening the new horizon in diagnosis and prevention of human diseases

  2023cites this paper
• Surface engineering Salmonella with pH‐responsive polyserotonin and self‐activated DNAzyme for better microbial therapy of tumor

  2023cites this paper
• Bacteria-Driven Cancer Therapy: Exploring Advancements and Challenges.

  2023cites this paper
• Combination of bacterial-targeted delivery of gold-based AIEgen radiosensitizer for fluorescence-image-guided enhanced radio-immunotherapy against advanced cancer

  2023cites this paper
• Anticancer activity of Pseudomonas aeruginosa derived peptide with iRGD in colon cancer therapy

  2023cites this paper
• Targeted deprivation of methionine with engineered Salmonella leads to oncolysis and suppression of metastasis in broad types of animal tumor models

  2023cites this paper
• Tryptophanase Expressed by Salmonella Halts Breast Cancer Cell Growth In Vitro and Inhibits Production of Immunosuppressive Kynurenine

  2023cites this paper
• Engineering versatile nano-bacteria hybrids for efficient tumor therapy

  2023cites this paper
• Blautia coccoides JCM1395T Achieved Intratumoral Growth with Minimal Inflammation: Evidence for Live Bacterial Therapeutic Potential by an Optimized Sample Preparation and Colony PCR Method

  2023cites this paper
• Bacteria therapeutics for cancer oncology: a crossroads for new paradigms.

  2022cites this paper
• Chemically Enhanced Live Probiotic for In Vivo Tumor Targeting and Inhibition

  2022cites this paper
• Bacteria-mediated cancer therapy: A versatile bio-sapper with translational potential

  2022cites this paper
• Salmonella as a Promising Curative Tool against Cancer

  2022cites this paper
• Bacteriolytic therapy with Clostridium ghonii for experimental solid tumors.

  2022cites this paper
• Targeted Depletion of Hyaluronic Acid Mitigates Murine Breast Cancer Growth

  2022cites this paper
• Recent advances in bacterial therapeutics based on sense and response

  2022cites this paper
• Salmonella-mediated blood‒brain barrier penetration, tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy

  2022cites this paper
• Efficient toxic doxorubicin hydrochloride removal from aqueous solutions using facial alumina nanorods

  2022cites this paper
• Impact of tumoral structure and bacterial species on growth and biodistribution of live bacterial therapeutics in xenografted tumours

  2022cites this paper
• Utilizing Bacteria-Derived Components for Cancer Immunotherapy

  2022cites this paper
• Recent Advances in Bacteria-Based Cancer Treatment

  2022cites this paper
• Intratumor microbiome in cancer progression: current developments, challenges and future trends

  2022cites this paper
• Bacterially mediated drug delivery and therapeutics: strategies and advancements.

  2022cites this paper
• Biosensors, modern technology for the detection of cancer-associated bacteria

  2022cites this paper
• A computational framework for investigating bacteria transport in microvasculature

  2022cites this paper
• Pattern of F-18 FDG Uptake in Colon Cancer after Bacterial Cancer Therapy Using Engineered Salmonella Typhimurium: A Preliminary In Vivo Study

  2022cites this paper
• Advances in Salmonella Typhimurium-based drug delivery system for cancer therapy.

  2022cites this paper
• Recent Update on Bacteria as a Delivery Carrier in Cancer Therapy: From Evil to Allies

  2022cites this paper
• Integration of Salmonella into Combination Cancer Therapy

  2021cites this paper
• Synthetic Biology Medicine and Bacteria-Based Cancer Therapeutics.

  2021cites this paper
• Bacterial-Based Cancer Therapy (BBCT): Recent Advances, Current Challenges, and Future Prospects for Cancer Immunotherapy

  2021cites this paper
• Bacteria and bacterial derivatives as delivery carriers for immunotherapy.

  2021cites this paper
• Innovative Approaches of Engineering Tumor-Targeting Bacteria with Different Therapeutic Payloads to Fight Cancer: A Smart Strategy of Disease Management

  2021cites this paper
• Theranostic Approaches Using Live Bacteria

  2021cites this paper
• Bacterial-Based Methods for Cancer Treatment: What We Know and Where We Are

  2021cites this paper
• Avengers against cancer: A new era of nano-biomaterial-based therapeutics

  2021cites this paper
• Multidimensional Role of Bacteria in Cancer: Mechanisms Insight, Diagnostic, Preventive and Therapeutic Potential.

  2021cites this paper
• Robust and Repeatable Biofabrication of Bacteria‐Mediated Drug Delivery Systems: Effect of Conjugation Chemistry, Assembly Process Parameters, and Nanoparticle Size

  2021cites this paper
• Emerging Applications of Bacteria as Antitumor Agents.

  2021cites this paper
• Recent Progress in the Molecular Imaging of Tumor-Treating Bacteria

  2021cites this paper
• Aptamer-assisted tumor localization of bacteria for enhanced biotherapy

  2021cites this paper
• Single-celled bacteria as tool for cancer therapy

  2021cites this paper
• Kinetic and Equilibrium Studies of Doxorubicin Adsorption onto Carbon Nanotubes

  2020cites this paper
• Immunopathology and Immunotherapy of Hodgkin Lymphoma

  2020cites this paper
• Data-driven statistical modeling of the emergent behavior of biohybrid microrobots

  2020cites this paper
• Engineering probiotics as living diagnostics and therapeutics for improving human health

  2020cites this paper
• Development of Dual-Scale Fluorescence Endoscopy for In Vivo Bacteria Imaging in an Orthotopic Mouse Colon Tumor Model

  2020cites this paper
• Inhibition of acute leukemia with attenuated Salmonella typhimurium strain VNP20009.

  2020cites this paper
• p28 Bacterial Peptide, as an Anticancer Agent

  2020cites this paper
• Bacteria-triggered tumor-specific thrombosis to enable potent photothermal immunotherapy of cancer

  2020cites this paper
• Bacteria and bacterial anticancer agents as a promising alternative for cancer therapeutics.

  2020cites this paper
• Salmonella enterica Typhimurium engineered for nontoxic systemic colonization of autochthonous tumors

  2020cites this paper
• Bacteria‐Derived Nanoparticles: Multifunctional Containers for Diagnostic and Therapeutic Applications

  2020cites this paper
• Acquired Fanconi Syndrome in a Patient with Nontyphoidal Salmonella Bacteremia

  2020cites this paper
• Microbes in Oncology: Controllable Strategies for Bacteria Therapy

  2020cites this paper
• "Trojan Horse" Salmonella Enabling Tumor Homing of Silver Nanoparticles via Neutrophil Infiltration for Synergistic Tumor Therapy and Enhanced Biosafety.

  2020cites this paper
• Immunopathology and Immunotherapy of Non-Hodgkin Lymphoma

  2020cites this paper
• Use of Tumor Targeting Bacteria as Cancer Therapeutic Agents and Drug Delivery Vehicles: A Conceptual Approach

  2019cites this paper
• Bacterial Targeting of Tumors

  2019cites this paper
• Mapping Salmonella typhimurium pathways using 13C metabolic flux analysis.

  2019cites this paper
• Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models

  2019cites this paper
• Bacteria-cancer interactions: bacteria-based cancer therapy

  2019cites this paper
• Therapeutic bacteria to combat cancer; current advances, challenges, and opportunities

  2019cites this paper
• Salmonella Typhimurium as an Anticancer Therapy: Recent Advances and Perspectives

  2019cites this paper
• The microbiome, cancer, and cancer therapy

  2019cites this paper