Role of carbohydrates in glycoprotein hormone signal transduction

No abstract is available for this paper.

• Publication year

  1989

• Venue

  The FASEB Journal

• Publication date

  1989-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1096/fasebj.3.8.2542111PMID 2542111
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Site specificity of the chorionic gonadotropin N-linked oligosaccharides in signal transduction.

  1989cited by this paper
• The role of the asparagine-linked oligosaccharides of the alpha subunit in the secretion and assembly of human chorionic gonadotrophin

  1988cited by this paper
• Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin. II. Distributions of sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.

  1988influential reference
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  1988cited by this paper
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  1988cited by this paper
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  1988cited by this paper
• Biochemical and Biological Characterization of LH and FSH Expressed by Recombinant DNA Technology

  1988cited by this paper
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  1988cited by this paper
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  1988cited by this paper
• Effect of deglycosylation on the structure and hormone-binding activity of the lutropin receptor.

  1988cited by this paper
• Asparagine-linked oligosaccharides on lutropin, follitropin, and thyrotropin. I. Structural elucidation of the sulfated and sialylated oligosaccharides on bovine, ovine, and human pituitary glycoprotein hormones.

  1988cited by this paper
• Conformation of the β subunit of deglycosylated human chorionic gonadotropin in the interaction at receptor sites

  1988cited by this paper
• The glycoprotein hormones: recent studies of structure‐function relationships

  1988cited by this paper
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  1988cited by this paper
• Glycosylation at specific sites of erythropoietin is essential for biosynthesis, secretion, and biological function.

  1988cited by this paper
• Naturally occurring antihormones: secretion of FSH antagonists by women treated with a GnRH analog.

  1988cited by this paper
• Co-localization of LHβ and FSHβ mRNAs in the porcine anterior pituitary by insitu hybridization with biotinylated probes

  1988cited by this paper
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  1988cited by this paper
• Antibody binding to the beta-subunit of deglycosylated chorionic gonadotropin converts the antagonist to an agonist.

  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
• Glycoprotein Hormone Genes

  1987cited by this paper
• Inhibition of adenylyl cyclase activity in rat corpora luteal tissue by glycopeptides of human chorionic gonadotropin and the alpha-subunit of human chorionic gonadotropin.

  1985cited by this paper
• 9 – Protein Glycosylation and Receptor–Ligand Interactions

  1985cited by this paper
• Characterization of gonadotropin-sensitive adenylate cyclase activity in human testis: uncoupling of the receptor-cyclase complex by specific hormonal antagonist.

  1985cited by this paper
• A role for glycosylation of the alpha subunit in transduction of biological signal in glycoprotein hormones.

  1985cited by this paper
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  1985cited by this paper
• An oligosaccharide of the O-linked type distinguishes the free from the combined form of hCG alpha subunit.

  1984cited by this paper
• Deglycosylated human chorionic gonadotropin. An antagonist to desensitization and down-regulation of the gonadotropin receptor-adenylate cyclase system.

  1983cited by this paper
• Naturally occurring forms of thyrotropin with low bioactivity and altered carbohydrate content act as competitive antagonists to more bioactive forms.

  1983cited by this paper
• Role of carbohydrate in human chorionic gonadotropin. Effect of deglycosylation on the subunit interaction and on its in vitro and in vivo biological properties.

  1983cited by this paper
• Purification of an alternate form of the alpha subunit of the glycoprotein hormones from bovine pituitaries and identification of its O-linked oligosaccharide.

  1983cited by this paper
• Chemically deglycosylated human chorionic gonadotropin subunits: characterization and biological properties.

  1983cited by this paper
• The alpha subunit of pituitary glycoprotein hormones. Formation of three-dimensional structure during cell-free biosynthesis.

  1983cited by this paper
• Biosynthesis and secretion of follicle-stimulating hormone.

  1983cited by this paper
• 1 – Gonadotropic Hormones: Relationship between Structure and Function with Emphasis on Antagonists

  1983cited by this paper
• Characterization and biological properties of chemically deglycosylated human chorionic gonadotropin. Role of carbohydrate moieties in adenylate cyclase activation.

  1982cited by this paper
• Biochemical, biological, and immunological properties of chemically deglycosylated human choriogonadotropin.

  1982cited by this paper
• Enzymatic deglycosylation of the subunits of chorionic gonadotropin. Effects on formation of tertiary structure and biological activity.

  1982cited by this paper
• Combination of rat lutropin subunits occurs early in the secretory pathway.

  1982cited by this paper
• Studies on pituitary follitropin. X. Biochemical, receptor binding and immunological properties of deglycosylated ovine hormone.

  1982cited by this paper
• Characterization of several clonal lines of cultured Leydig tumor cells: gonadotropin receptors and steroidogenic responses.

  1981cited by this paper
• Glycoprotein hormones: structure and function.

  1981cited by this paper
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  1979cited by this paper
• Receptor binding, biological, and immunological properties of chemically deglycosylated pituitary lutropin.

  1979cited by this paper
• Action of PMSG and asialo-PMSG on rat Leydig and granulosa cells.

  1978cited by this paper
• Role of carbohydrate of human chorionic gonadotropin in the mechanism of hormone action.

  1975cited by this paper

• Multiple mechanisms of allosteric regulation of the luteninizing hormone receptor

  2024cites this paper
• Hormonal and Allosteric Regulation of the Luteinizing Hormone/Chorionic Gonadotropin Receptor.

  2024cites this paper
• Single-chain human follicle-stimulating hormone with a di-N-glycosylated linker.

  2024cites this paper
• Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq

  2024cites this paper
• Differential effects of follicle-stimulating hormone glycoforms on the transcriptome profile of cultured rat granulosa cells as disclosed by RNA-seq

  2023cites this paper
• Glycoprotein hormone receptors in GtoPdb v.2023.1

  2023cites this paper
• Crystal structure of LGR ligand α2/β5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones

  2022cites this paper
• Glycoprotein G-protein Coupled Receptors in Disease: Luteinizing Hormone Receptors and Follicle Stimulating Hormone Receptors

  2020cites this paper
• In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity

  2020cites this paper
• 1,3-Dipolar cycloaddition reaction on carbohydrate template: Stereoselective synthesis of glycospiroheterocycles

  2020cites this paper
• Hyperglycosylated hCG activates LH/hCG-receptor with lower activity than hCG.

  2019cites this paper
• Glycoprotein hormone receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

  2019cites this paper
• Gonadotropin Hormones and Their Receptors

  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
• Preparation, characterization and application of long-acting FSH analogs for assisted reproduction.

  2017cites this paper
• Boron-based small molecules in disease detection and treatment (2013–2016)

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• Clinical Applications of Gonadotropins in the Male.

  2016cites this paper
• The Follitropin Receptor: Matching Structure and Function

  2016cites this paper
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  2016cites this paper
• Discovery and Development of Small Molecule Allosteric Modulators of Glycoprotein Hormone Receptors

  2015cites this paper
• Purification of equine chorionic gonadotropin (eCG) using magnetic ion exchange adsorbents in combination with high‐gradient magnetic separation

  2015cites this paper
• Structure–Function Relationships of Glycoprotein Hormones and Their Subunits’ Ancestors

  2015cites this paper
• Chemical Synthesis of the β-Subunit of Human Luteinizing (hLH) and Chorionic Gonadotropin (hCG) Glycoprotein Hormones

  2014cites this paper
• Posttranslational Modifications to Improve Biopharmaceuticals

  2013cites this paper
• Oligomers of beta-L-arabinosides of hydroxyproline : synthesis of the carbohydrate epitope of the Art v 1 allergen

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• The Concise Guide to Pharmacology 2013/14: G Protein-Coupled Receptors

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• Ovotoxic Effects of Galactose Involve Attenuation of Follicle-Stimulating Hormone Bioactivity and Up-Regulation of Granulosa Cell p53 Expression

  2012cites this paper
• Probing the frontiers of glycoprotein synthesis: the fully elaborated β-subunit of the human follicle-stimulating hormone.

  2012cites this paper
• Guide to Receptors and Channels (GRAC), 5th edition

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• A novel glycosylation signal regulates transforming growth factor beta receptors as evidenced by endo-beta-galactosidase C expression in rodent cells.

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  2010cites this paper
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• Toward fully synthetic homogeneous beta-human follicle-stimulating hormone (beta-hFSH) with a biantennary N-linked dodecasaccharide. synthesis of beta-hFSH with chitobiose units at the natural linkage sites.

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  2008cites this paper
• Mise au point Les glycoprotéines placentaires chez les mammifères Placental glycoproteins in the mammals

  2008cites this paper
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  2008cites this paper
• Expression of a novel follicle-stimulating hormone glycoform relating to fertility

  2008cites this paper
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  2006cites this paper
• Conjugated Estrogens and Tibolone Modify the Gonadotrophin Glycosylation Pattern in Postmenopausal Women

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  2005cites this paper
• A Single-Chain Tetradomain Glycoprotein Hormone Analog Elicits Multiple Hormone Activities In Vivo1

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• Role of the Carbohydrate Chain and Two Phosphate Moieties in the Heat-Induced Aggregation of Hen Ovalbumin

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  2003cites this paper
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  2003cites this paper
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  2002cites this paper
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• Mobilities of the inner three core residues and the Man(alpha 1--6) branch of the glycan at Asn78 of the alpha-subunit of human chorionic gonadotropin are restricted by the protein.

  1998cites this paper