Cleavage of cohesin rings coordinates the separation of centrioles and chromatids

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Nature Cell Biology

• Publication date

  2011-07-10

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1038/ncb2280PMID 21743463
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells.

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  2009cited by this paper
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  2008cited by this paper
• Cohesin protein SMC1 is a centrosomal protein.

  2008cited by this paper
• The cohesin ring concatenates sister DNA molecules

  2008cited by this paper
• sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1.

  2008cited by this paper
• Phosphorylation-dependent Binding of Cyclin B1 to a Cdc6-like Domain of Human Separase*

  2008cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• Cyclin-B1-mediated inhibition of excess separase is required for timely chromosome disjunction

  2006cited by this paper
• Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase.

  2006cited by this paper
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  2006cited by this paper
• Shugoshin collaborates with protein phosphatase 2A to protect cohesin

  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• Stringent doxycycline-dependent control of gene activities using an episomal one-vector system

  2005cited by this paper
• Dissociation of Cohesin from Chromosome Arms and Loss of Arm Cohesion during Early Mitosis Depends on Phosphorylation of SA2

  2005cited by this paper
• Shugoshin Prevents Dissociation of Cohesin from Centromeres During Mitosis in Vertebrate Cells

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  2004cited by this paper
• Human Bub1 protects centromeric sister-chromatid cohesion through Shugoshin during mitosis

  2004cited by this paper
• Regulation of sister chromatid cohesion between chromosome arms.

  2004cited by this paper
• Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles.

  2003cited by this paper
• Centrosome number is controlled by a centrosome-intrinsic block to reduplication

  2003cited by this paper
• Chromosomal cohesin forms a ring.

  2003cited by this paper
• The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase.

  2002cited by this paper
• Dual inhibition of sister chromatid separation at metaphase.

  2001cited by this paper
• Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

  2001cited by this paper
• A Potential Role for Human Cohesin in Mitotic Spindle Aster Assembly*

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• Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

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• Live Cell Monitoring of Separase Activity, a Key Enzymatic Reaction for Chromosome Segregation, with Chimeric FRET-Based Molecular Sensor upon Cell Cycle Progression

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• Balancing Plk1 activity levels: The secret of synchrony between the cell and the centrosome cycle

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• Loss of the mitochondrial protein SPD-3 elevates PLK-1 levels and dysregulates mitotic events

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• Sgo1 interacts with CENP-A to guide accurate chromosome segregation in mitosis

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• Alström Syndrome protein Alms1 is required for maintaining meiotic centriole engagement in spermatocytes of Drosophila

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• Hornerin mediates phosphorylation of the polo-box domain in Plk1 by Chk1 to induce death in mitosis

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• Gene Expression Pattern of ESPL1, PTTG1 and PTTG1IP Can Potentially Predict Response to TKI First-Line Treatment of Patients with Newly Diagnosed CML

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• Separase and Roads to Disengage Sister Chromatids during Anaphase

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• Mitotic events depend on regulation of PLK-1 levels by the mitochondrial protein SPD-3

  2023cites this paper
• Identification of Novel Small Molecules Targeting the Protease Activity of Separase

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• Mapping separase-mediated cleavage in situ

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• Piezo mechanosensory channels regulate centrosome integrity and mitotic entry

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• Cartwheel disassembly regulated by CDK1-cyclin B kinase allows human centriole disengagement and licensing

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• Role of Polo-like Kinases Plk1 and Plk4 in the Initiation of Centriole Duplication—Impact on Cancer

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